Mechanisms of action of infliximab in inflammatory bowel disease: an anti-inflammatory multitasker

scientific article published on July 2008

Mechanisms of action of infliximab in inflammatory bowel disease: an anti-inflammatory multitasker is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S1590-8658(08)60530-7
P698PubMed publication ID18598993

P2093author name stringS Danese
P2860cites workTNF-alpha blockade down-regulates the CD40/CD40L pathway in the mucosal microcirculation: a novel anti-inflammatory mechanism of infliximab in Crohn's disease.Q52568596
Impaired On/Off Regulation of TNF Biosynthesis in Mice Lacking TNF AU-Rich ElementsQ62819809
INFLIXIMAB DOWNREGULATES INTERFERON-γ PRODUCTION IN ACTIVATED GUT T-LYMPHOCYTES FROM PATIENTS WITH CROHN'S DISEASEQ63727345
Infliximab induces apoptosis in monocytes from patients with chronic active Crohn's disease by using a caspase-dependent pathwayQ77061247
Functional modulation of Crohn's disease myofibroblasts by anti-tumor necrosis factor antibodiesQ80611351
Serum bFGF and VEGF correlate respectively with bowel wall thickness and intramural blood flow in Crohn's diseaseQ80837962
TNF/TNFR family members in costimulation of T cell responsesQ28240053
TNF-alpha neutralization ameliorates the severity of murine Crohn's-like ileitis by abrogation of intestinal epithelial cell apoptosisQ30310991
Review article: targeting TNF alpha as a key cytokine in the inflammatory processes of Crohn's disease--the mechanisms of action of infliximabQ33793922
Etiopathogenesis of inflammatory bowel diseasesQ33866988
Anti-tumor necrosis factor treatment restores the gut barrier in Crohn's diseaseQ34145454
Defective mucosal T cell death is sustainably reverted by infliximab in a caspase dependent pathway in Crohn's diseaseQ35596219
The CD40/CD40L costimulatory pathway in inflammatory bowel diseaseQ35596631
Increased gut permeability in Crohn's disease: is TNF the link?Q35948456
Adhesion molecules in inflammatory bowel disease: therapeutic implications for gut inflammation.Q36259898
Alterations of mesenchymal and endothelial cells in inflammatory bowel diseasesQ36451319
Immune regulation by microvascular endothelial cells: directing innate and adaptive immunity, coagulation, and inflammationQ36809550
Inflammation and the mucosal microcirculation in inflammatory bowel disease: the ebb and flowQ36838888
Infliximab treatment induces apoptosis of lamina propria T lymphocytes in Crohn's disease.Q41941349
Impact of infliximab on serum leptin levels in patients with Crohn's diseaseQ46398438
Inflammatory bowel disease: etiology and pathogenesisQ47899867
P921main subjectinflammationQ101991
inflammatory bowel diseasesQ917447
P304page(s)S225-8
P577publication date2008-07-01
P1433published inDigestive and Liver DiseaseQ15766194
P1476titleMechanisms of action of infliximab in inflammatory bowel disease: an anti-inflammatory multitasker
P478volume40 Suppl 2

Reverse relations

cites work (P2860)
Q38788593A 53-year-old man with dyspnoea, respiratory failure, consistent with infliximab-induced acute interstitial pneumonitis after an accelerated induction dosing schedule
Q37816445Adalimumab in ulcerative colitis: hypes and hopes
Q60313563Anti-TNF-α Therapy Suppresses Proinflammatory Activities of Mucosal Neutrophils in Inflammatory Bowel Disease
Q46495260Balancing inflammatory, lipid, and xenobiotic signaling pathways by VSL#3, a biotherapeutic agent, in the treatment of inflammatory bowel disease
Q92589685Capturing the Biologic Onset of Inflammatory Bowel Diseases: Impact on Translational and Clinical Science
Q26994776Clinical use and mechanisms of infliximab treatment on inflammatory bowel disease: a recent update
Q54318216Decreased mucosal sulfide detoxification is related to an impaired butyrate oxidation in ulcerative colitis.
Q42632507Early diagnosis and treatment of postoperative endoscopic recurrence of Crohn's disease: partial benefit by infliximab--a pilot study.
Q91631853Endothelial MT1-MMP targeting limits intussusceptive angiogenesis and colitis via TSP1/nitric oxide axis
Q51584924Evaluation of a daily practice composite score for the assessment of Crohn's disease: the treatment impact of certolizumab pegol.
Q39426072Genetics and immunodysfunction underlying Behçet's disease and immunomodulant treatment approaches
Q37310621Immunomodulatory and anti-inflammatory effects of chondroitin sulphate
Q57265340Impaired butyrate oxidation in ulcerative colitis is due to decreased butyrate uptake and a defect in the oxidation pathway*
Q37586911Maintenance treatment with infliximab for the management of Crohn's disease in adults
Q42029056Malignant melanoma of the ileo-anal pouch anastomosis after restorative proctocolectomy for ulcerative colitis: report of a case
Q37547257Overview of biologic therapy for Crohn's disease
Q26776139Promising biological therapies for ulcerative colitis: A review of the literature
Q64911664Reproducing the human mucosal environment ex vivo: inflammatory bowel disease as a paradigm.
Q34167771Response to biologic therapy in Crohn's disease is improved with early treatment: an analysis of health claims data
Q38104578State-of-the-art medical prevention of postoperative recurrence of Crohn's disease
Q38191334Stopping anti-TNF agents in patients with Crohn's disease in remission: is it a feasible long-term strategy?
Q47368079Switching from infliximab innovator to biosimilar in patients with inflammatory bowel disease: a 12-month multicentre observational prospective cohort study.
Q58611213The first World Health Organization International Standard for infliximab products: A step towards maintaining harmonized biological activity
Q38881849The molecular biology of matrix metalloproteinases and tissue inhibitors of metalloproteinases in inflammatory bowel diseases
Q45839795Therapeutic Targets for Emerging Biologic Therapies in IBD.
Q92875750Towards the Oral Treatment of Ileo-Colonic Inflammatory Bowel Disease with Infliximab Tablets: Development and Validation of the Production Process
Q39020790Tumor necrosis factor suppresses NR5A2 activity and intestinal glucocorticoid synthesis to sustain chronic colitis

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