| review article | Q7318358 |
| scholarly article | Q13442814 |
| P50 | author | Katrin Zeilinger | Q56961667 |
| P2093 | author name string | Daniel Seehofer | |
| Fanny Knöspel | |||
| Georg Damm | |||
| Nora Freyer | |||
| P2860 | cites work | The canals of Hering and hepatic stem cells in humans | Q73208585 |
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| Long-term culture and cryopreservation does not affect the stability and functionality of human embryonic stem cell-derived hepatocyte-like cells | Q86527261 | ||
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| Embryonic stem cell lines derived from human blastocysts | Q27861010 | ||
| Differences in the Epigenetic Regulation of Cytochrome P450 Genes between Human Embryonic Stem Cell-Derived Hepatocytes and Primary Hepatocytes | Q28546589 | ||
| Development and characterization of a new human hepatic cell line. | Q30391217 | ||
| Contribution of hepatic lineage stage-specific donor memory to the differential potential of induced mouse pluripotent stem cells | Q33595592 | ||
| Modeling inherited metabolic disorders of the liver using human induced pluripotent stem cells. | Q33672762 | ||
| Dynamic interplay of flow and collagen stabilizes primary hepatocytes culture in a microfluidic platform. | Q33675139 | ||
| Efficient endoderm induction from human pluripotent stem cells by logically directing signals controlling lineage bifurcations. | Q33711163 | ||
| Effect of cell-cell interactions in preservation of cellular phenotype: cocultivation of hepatocytes and nonparenchymal cells. | Q33764015 | ||
| Explanted diseased livers - a possible source of metabolic competent primary human hepatocytes | Q33855523 | ||
| Isolation of primary human hepatocytes from normal and diseased liver tissue: a one hundred liver experience | Q33867498 | ||
| Gene expression profiling of extracellular matrix as an effector of human hepatocyte phenotype in primary cell culture | Q33901799 | ||
| DNA methylation dynamics in human induced pluripotent stem cells over time | Q33921145 | ||
| Stem cells in gastroenterology and hepatology | Q33989211 | ||
| Modeling host interactions with hepatitis B virus using primary and induced pluripotent stem cell-derived hepatocellular systems. | Q34082747 | ||
| The promotion of hepatic maturation of human pluripotent stem cells in 3D co-culture using type I collagen and Swiss 3T3 cell sheets | Q39374697 | ||
| Hepatic 3D cultures but not 2D cultures preserve specific transporter activity for acetaminophen-induced hepatotoxicity | Q39409174 | ||
| Construction and characterization of hepatocyte nuclear factor HNF4alpha1 over-expressing cell line derived from human hepatoma HepG2 cells | Q39483588 | ||
| Cytochrome P450-dependent metabolism in HepaRG cells cultured in a dynamic three-dimensional bioreactor | Q39570948 | ||
| Hepatic differentiation of human embryonic stem cells is promoted by three-dimensional dynamic perfusion culture conditions | Q39611494 | ||
| Cryopreservation of human vascular umbilical cord cells under good manufacturing practice conditions for future cell banks | Q39616839 | ||
| HepaRG human hepatic cell line utility as a surrogate for primary human hepatocytes in drug metabolism assessment in vitro | Q39705178 | ||
| Properties of hepatocyte-like cell clusters from human adipose tissue-derived mesenchymal stem cells | Q39785968 | ||
| Human parenchymal and non-parenchymal liver cell isolation, culture and characterization | Q40706779 | ||
| Characterization of primary human hepatocyte spheroids as a model system for drug-induced liver injury, liver function and disease | Q40770241 | ||
| Gene networks and transcription factor motifs defining the differentiation of stem cells into hepatocyte-like cells. | Q41196554 | ||
| Investigation of omeprazole and phenacetin first-pass metabolism in humans using a microscale bioreactor and pharmacokinetic models | Q41441454 | ||
| Multipotent adult progenitor cells from bone marrow differentiate into functional hepatocyte-like cells | Q34129368 | ||
| Mechanisms of acetaminophen-induced cell death in primary human hepatocytes. | Q34225946 | ||
| Cryopreservation and Enumeration of Human Endothelial Progenitor and Endothelial Cells for Clinical Trials | Q34322794 | ||
| Sandwich-cultured hepatocytes: utility for in vitro exploration of hepatobiliary drug disposition and drug-induced hepatotoxicity | Q34330504 | ||
| A comparative study of genome-wide transcriptional profiles of primary hepatocytes in collagen sandwich and monolayer cultures | Q34334983 | ||
| An algorithm that predicts the viability and the yield of human hepatocytes isolated from remnant liver pieces obtained from liver resections. | Q34337858 | ||
| Small-molecule-driven hepatocyte differentiation of human pluripotent stem cells | Q34474853 | ||
| Prediction of interindividual differences in hepatic functions and drug sensitivity by using human iPS-derived hepatocytes. | Q34601581 | ||
| Multi-cell type human liver microtissues for hepatotoxicity testing | Q34645248 | ||
| HHEX promotes hepatic-lineage specification through the negative regulation of eomesodermin. | Q35126482 | ||
| Human iPSC-derived hepatocyte-like cells support Plasmodium liver-stage infection in vitro | Q35222586 | ||
| High throughput micro-well generation of hepatocyte micro-aggregates for tissue engineering | Q35227071 | ||
| Promotion of mesenchymal-to-epithelial transition by Rac1 inhibition with small molecules accelerates hepatic differentiation of mesenchymal stromal cells | Q35549853 | ||
| DMSO efficiently down regulates pluripotency genes in human embryonic stem cells during definitive endoderm derivation and increases the proficiency of hepatic differentiation | Q35557287 | ||
| Hepatocyte culture in autologous decellularized spleen matrix. | Q35558171 | ||
| Prediction of Drug-Induced Liver Injury in Micropatterned Co-cultures Containing iPSC-Derived Human Hepatocytes | Q35567915 | ||
| Development and characterization of human-induced pluripotent stem cell-derived cholangiocytes | Q35661071 | ||
| Efficient generation of functional hepatocytes from human embryonic stem cells and induced pluripotent stem cells by HNF4α transduction. | Q35665145 | ||
| Design of a Vitronectin-Based Recombinant Protein as a Defined Substrate for Differentiation of Human Pluripotent Stem Cells into Hepatocyte-Like Cells | Q35755765 | ||
| Cost-effective differentiation of hepatocyte-like cells from human pluripotent stem cells using small molecules | Q35756499 | ||
| Modeling hepatitis C virus infection using human induced pluripotent stem cells | Q35787014 | ||
| All-In-One: Advanced preparation of Human Parenchymal and Non-Parenchymal Liver Cells | Q35788567 | ||
| Characterization of primary human hepatocytes, HepG2 cells, and HepaRG cells at the mRNA level and CYP activity in response to inducers and their predictivity for the detection of human hepatotoxins | Q35828228 | ||
| Preclinical Evaluation of Liposomal C8 Ceramide as a Potent anti-Hepatocellular Carcinoma Agent | Q35884228 | ||
| Genetic Variability Overrides the Impact of Parental Cell Type and Determines iPSC Differentiation Potential | Q35896332 | ||
| Development of complex-shaped liver multicellular spheroids as a human-based model for nanoparticle toxicity assessment in vitro | Q35908689 | ||
| Improved cryopreservation of human hepatocytes using a new xeno free cryoprotectant solution | Q36002026 | ||
| Dual-Purpose Bioreactors to Monitor Noninvasive Physical and Biochemical Markers of Kidney and Liver Scaffold Recellularization | Q36123284 | ||
| Subtoxic Concentrations of Hepatotoxic Drugs Lead to Kupffer Cell Activation in a Human In Vitro Liver Model: An Approach to Study DILI. | Q36146271 | ||
| Human hepatic stem cells from fetal and postnatal donors | Q36229597 | ||
| Recombinant Laminins Drive the Differentiation and Self-Organization of hESC-Derived Hepatocytes | Q36379726 | ||
| Hepatic differentiation induced by oncostatin M attenuates fetal liver hematopoiesis | Q36393788 | ||
| Involvement of cell junctions in hepatocyte culture functionality | Q36523471 | ||
| The importance of the interaction between hepatocyte and hepatic stellate cells in fibrogenesis induced by fatty accumulation | Q41657711 | ||
| Featured Article: Isolation, characterization, and cultivation of human hepatocytes and non-parenchymal liver cells | Q42430038 | ||
| In-depth physiological characterization of primary human hepatocytes in a 3D hollow-fiber bioreactor. | Q42485953 | ||
| Regulation of cell morphology and cytochrome P450 expression in human hepatocytes by extracellular matrix and cell-cell interactions | Q42512073 | ||
| Polarized location of SLC and ABC drug transporters in monolayer-cultured human hepatocytes | Q42702058 | ||
| Use of micropatterned cocultures to detect compounds that cause drug-induced liver injury in humans | Q42714258 | ||
| Hepatic differentiation of human embryonic stem cells as microscaled multilayered colonies leading to enhanced homogeneity and maturation | Q42798977 | ||
| Hepatic differentiation from human embryonic stem cells using stromal cells | Q42807201 | ||
| Generation of functional hepatocytes from human embryonic stem cells under chemically defined conditions that recapitulate liver development | Q43124071 | ||
| Generation of functional cholangiocyte-like cells from human pluripotent stem cells and HepaRG cells. | Q43130050 | ||
| A simple isolation and cryopreservation method for adult human hepatocytes. | Q43234725 | ||
| Suppression of hepatocyte CYP1A2 expression by Kupffer cells via AhR pathway: the central role of proinflammatory cytokines | Q43425840 | ||
| Characterization of hepatic markers in human Wharton's Jelly-derived mesenchymal stem cells | Q43623142 | ||
| A comprehensive evaluation of metabolic activity and intrinsic clearance in suspensions and monolayer cultures of cryopreserved primary human hepatocytes | Q43988351 | ||
| Morphological behaviour and metabolic capacity of cryopreserved human primary hepatocytes cultivated in a perfused multiwell device | Q44179560 | ||
| Enhanced in vitro maturation of fetal mouse liver cells with oncostatin M, nicotinamide, and dimethyl sulfoxide | Q44181753 | ||
| Immunohistochemical evidence for hepatic progenitor cells in liver diseases | Q44187117 | ||
| Human hepatocytes and endothelial cells in organotypic membrane systems | Q44318937 | ||
| 3D spheroid culture of hESC/hiPSC-derived hepatocyte-like cells for drug toxicity testing | Q45231872 | ||
| Isolation and characterization of adult human liver progenitors from ischemic liver tissue derived from therapeutic hepatectomies | Q46183577 | ||
| Serum-free culture of primary human hepatocytes in a miniaturized hollow-fibre membrane bioreactor for pharmacological in vitro studies | Q46467026 | ||
| A long-term three dimensional liver co-culture system for improved prediction of clinically relevant drug-induced hepatotoxicity | Q46648491 | ||
| Cryopreservation of hepatic stellate cells | Q46708534 | ||
| Oxidative stress triggers cytokinesis failure in hepatocytes upon isolation | Q46763677 | ||
| Native umbilical cord matrix stem cells express hepatic markers and differentiate into hepatocyte-like cells. | Q46776375 | ||
| Evaluation of human hepatocytes cultured by three-dimensional spheroid systems for drug metabolism | Q47889610 | ||
| Vascularized and functional human liver from an iPSC-derived organ bud transplant | Q48453997 | ||
| Characterization of rat and human Kupffer cells after cryopreservation. | Q50471715 | ||
| The protective effects of carvacrol and thymol against paracetamol-induced toxicity on human hepatocellular carcinoma cell lines (HepG2). | Q50888253 | ||
| Incubation with dimethyl sulfoxide prior to cryopreservation improves functionality of thawed human primary hepatocytes. | Q50908128 | ||
| A liver-on-a-chip platform with bioprinted hepatic spheroids. | Q51472011 | ||
| A microfluidically perfused three dimensional human liver model. | Q51483766 | ||
| Time course of primary liver cell reorganization in three-dimensional high-density bioreactors for extracorporeal liver support: an immunohistochemical and ultrastructural study. | Q51617067 | ||
| Tissue collection, transport and isolation procedures required to optimize human hepatocyte isolation from waste liver surgical resections. A multilaboratory study. | Q51637422 | ||
| Stiffness of hyaluronic acid gels containing liver extracellular matrix supports human hepatocyte function and alters cell morphology. | Q51644762 | ||
| Effect of human patient plasma ex vivo treatment on gene expression and progenitor cell activation of primary human liver cells in multi-compartment 3D perfusion bioreactors for extra-corporeal liver support. | Q51775511 | ||
| Use of primary human liver cells originating from discarded grafts in a bioreactor for liver support therapy and the prospects of culturing adult liver stem cells in bioreactors: a morphologic study | Q51822426 | ||
| The phenotypes of pluripotent human hepatic progenitors. | Q52020121 | ||
| A micropatterned hepatocyte coculture model for assessment of liver toxicity using high-content imaging analysis. | Q52765200 | ||
| Analysis of drug metabolism activities in a miniaturized liver cell bioreactor for use in pharmacological studies. | Q52887959 | ||
| Scaling down of a clinical three-dimensional perfusion multicompartment hollow fiber liver bioreactor developed for extracorporeal liver support to an analytical scale device useful for hepatic pharmacological in vitro studies. | Q52899422 | ||
| Induced pluripotent stem cell-derived hepatocytes and endothelial cells in multi-component hydrogel fibers for liver tissue engineering. | Q53563428 | ||
| Reconstruction of hepatic organoid by rat small hepatocytes and hepatic nonparenchymal cells. | Q53815640 | ||
| Human primary cultured hepatic stellate cells can be cryopreserved | Q54416913 | ||
| Directed differentiation of murine-induced pluripotent stem cells to functional hepatocyte-like cells | Q56777683 | ||
| Pancreatic progenitor-derived hepatocytes are viable and functional in a 3D high density bioreactor culture system | Q56963127 | ||
| Human Hepatocytes: Isolation, Culture, and Quality Procedures | Q57767532 | ||
| Ammonia inhibition of protein degradation in isolated rat hepatocytes. Quantitative ultrastructural alterations in the lysosomal system | Q67756304 | ||
| Culture matrix configuration and composition in the maintenance of hepatocyte polarity and function | Q71359240 | ||
| Molecular mechanisms underlying the dedifferentiation process of isolated hepatocytes and their cultures. | Q36569873 | ||
| Cholangiocytes derived from human induced pluripotent stem cells for disease modeling and drug validation | Q36621970 | ||
| The human hepatoma HepaRG cells: a highly differentiated model for studies of liver metabolism and toxicity of xenobiotics | Q36714606 | ||
| Directed assembly of cell-laden microgels for fabrication of 3D tissue constructs | Q36775306 | ||
| Highly efficient differentiation of hESCs to functional hepatic endoderm requires ActivinA and Wnt3a signaling | Q36843548 | ||
| Production of hepatocyte-like cells from human pluripotent stem cells. | Q36904417 | ||
| Hepatocyte polarity | Q36972087 | ||
| Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME. | Q37121662 | ||
| Recent advances in the morphological and functional heterogeneity of the biliary epithelium | Q37662251 | ||
| AR42J-B-13 cell: an expandable progenitor to generate an unlimited supply of functional hepatocytes. | Q37777830 | ||
| Stem cells in pharmaceutical biotechnology | Q37929232 | ||
| The HepaRG cell line: a unique in vitro tool for understanding drug metabolism and toxicology in human | Q38008484 | ||
| Primary hepatocyte cultures as prominent in vitro tools to study hepatic drug transporters. | Q38077993 | ||
| "Epigenetic memory" phenomenon in induced pluripotent stem cells | Q38181118 | ||
| Development of novel tools for the in vitro investigation of drug-induced liver injury. | Q38544071 | ||
| Induction of MITF expression in human cholangiocarcinoma cells and hepatocellular carcinoma cells by cyclopamine, an inhibitor of the Hedgehog signaling | Q38803094 | ||
| Micropatterned coculture of primary human hepatocytes and supportive cells for the study of hepatotropic pathogens. | Q38818466 | ||
| Toxicogenomics-based prediction of acetaminophen-induced liver injury using human hepatic cell systems. | Q38825405 | ||
| Development of HepG2-derived cells expressing cytochrome P450s for assessing metabolism-associated drug-induced liver toxicity | Q38827021 | ||
| One Standardized Differentiation Procedure Robustly Generates Homogenous Hepatocyte Cultures Displaying Metabolic Diversity from a Large Panel of Human Pluripotent Stem Cells | Q38834246 | ||
| Bioprinting Cellularized Constructs Using a Tissue-specific Hydrogel Bioink | Q38868772 | ||
| Establishment of a hepatocyte-kupffer cell coculture model for assessment of proinflammatory cytokine effects on metabolizing enzymes and drug transporters | Q38903502 | ||
| Phenotypic and functional analyses show stem cell-derived hepatocyte-like cells better mimic fetal rather than adult hepatocytes. | Q38933941 | ||
| Human Hepatocyte Isolation: Does Portal Vein Embolization Affect the Outcome? | Q38955155 | ||
| HepaRG microencapsulated spheroids in DMSO-free culture: novel culturing approaches for enhanced xenobiotic and biosynthetic metabolism | Q38967712 | ||
| Long-term chronic toxicity testing using human pluripotent stem cell-derived hepatocytes | Q38979558 | ||
| Critical differences in toxicity mechanisms in induced pluripotent stem cell-derived hepatocytes, hepatic cell lines and primary hepatocytes | Q38986528 | ||
| Generation of hepatocyte-like cells from human induced pluripotent stem (iPS) cells by co-culturing embryoid body cells with liver non-parenchymal cell line TWNT-1. | Q39027784 | ||
| Enhancing the functional maturity of induced pluripotent stem cell-derived human hepatocytes by controlled presentation of cell-cell interactions in vitro | Q39094576 | ||
| Newly established human liver cell line: a potential cell source for the bioartificial liver in the future | Q39135603 | ||
| Evaluating the Effects of Dithiothreitol and Fructose on Cell Viability and Function of Cryopreserved Primary Rat Hepatocytes and HepG2 Cell Line. | Q39166511 | ||
| Application of three-dimensional culture conditions to human embryonic stem cell-derived definitive endoderm cells enhances hepatocyte differentiation and functionality | Q39273051 | ||
| Hepatic differentiation and maturation of human embryonic stem cells cultured in a perfused three-dimensional bioreactor | Q39280479 | ||
| Accurate prediction of drug-induced liver injury using stem cell-derived populations | Q39283236 | ||
| P433 | issue | 15 | |
| P304 | page(s) | 1684-1698 | |
| P577 | publication date | 2016-07-05 | |
| P1433 | published in | Experimental Biology and Medicine | Q15716535 |
| P1476 | title | Cell sources for in vitro human liver cell culture models | |
| P478 | volume | 241 |
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