Cyclic pyrrole-imidazole polyamides targeted to the androgen response element

scientific article published on May 2009

Cyclic pyrrole-imidazole polyamides targeted to the androgen response element is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1021/JA901309Z
P932PMC publication ID2689155
P698PubMed publication ID19413319
P5875ResearchGate publication ID24399692

P50authorPeter DervanQ907746
Christian DoseQ74956528
P2093author name stringJohn W Phillips
David M Chenoweth
Daniel A Harki
P2860cites workA cell-permeable synthetic transcription factor mimicQ79919848
Suppression of androgen receptor-mediated gene expression by a sequence-specific DNA-binding polyamideQ24669875
Crystal structures of nucleosome core particles in complex with minor groove DNA-binding ligandsQ27640403
Structural basis for G.C recognition in the DNA minor grooveQ27748839
A structural basis for recognition of A.T and T.A base pairs in the minor groove of B-DNAQ27765390
Recognition of the DNA minor groove by pyrrole-imidazole polyamidesQ28182798
Molecular recognition of DNA by small moleculesQ28216029
Pharmacokinetics in drug discoveryQ28236553
Recognition of the four Watson-Crick base pairs in the DNA minor groove by synthetic ligandsQ28261362
Recognition of DNA by designed ligands at subnanomolar concentrationsQ28284127
Cellular uptake of N-methylpyrrole/N-methylimidazole polyamide-dye conjugatesQ31099903
Nuclear localization of pyrrole–imidazole polyamide–fluorescein conjugates in cell cultureQ33193534
Improved nuclear localization of DNA-binding polyamidesQ33266897
Next generation hairpin polyamides with (R)-3,4-diaminobutyric acid turn unitQ33331950
Quantitating the concentration of Py-Im polyamide-fluorescein conjugates in live cellsQ33340423
Completion of a Programmable DNA-Binding Small Molecule LibraryQ33348532
Molecular recognition of the nucleosomal "supergroove".Q33781158
Cyclic polyamides for recognition in the minor groove of DNAQ33840166
Influence of structural variation on nuclear localization of DNA-binding polyamide-fluorophore conjugatesQ34334052
In vivo imaging of pyrrole-imidazole polyamides with positron emission tomographyQ36861667
Solution-phase synthesis of pyrrole-imidazole polyamidesQ37209301
Binding of a hairpin polyamide in the minor groove of DNA: sequence-specific enthalpic discriminationQ37400189
Structural basis of androgen receptor binding to selective androgen response elements.Q37414946
Inhibition of vascular endothelial growth factor with a sequence-specific hypoxia response element antagonistQ37695740
Footprinting methods for analysis of pyrrole-imidazole polyamide/DNA complexesQ38298047
NMR structure of a cyclic polyamide-DNA complexQ38339789
Accessibility of Nuclear Chromatin by DNA Binding PolyamidesQ38349766
Modulating hypoxia-inducible transcription by disrupting the HIF-1-DNA interfaceQ41857906
Sequence-specific recognition of DNA in the nucleosome by pyrrole-imidazole polyamidesQ43633078
Controlling the intracellular localization of fluorescent polyamide analogues in cultured cellsQ44406422
Synthesis of N-methylpyrrole and N-methylimidazole amino acids suitable for solid-phase synthesisQ45139863
Discrimination of A/T sequences in the minor groove of DNA within a cyclic polyamide motifQ46538655
Novel gene silencer pyrrole-imidazole polyamide targeting lectin-like oxidized low-density lipoprotein receptor-1 attenuates restenosis of the artery after injuryQ46562572
Development of gene silencing pyrrole-imidazole polyamide targeting the TGF-beta1 promoter for treatment of progressive renal diseasesQ46863385
Suppression of VEGF transcription in renal cell carcinoma cells by pyrrole-imidazole hairpin polyamides targeting the hypoxia responsive element.Q54605056
Fmoc solid phase synthesis of polyamides containing pyrrole and imidazole amino acidsQ73868156
The thermodynamics of polyamide-DNA recognition: hairpin polyamide binding in the minor groove of duplex DNAQ74456843
P433issue20
P407language of work or nameEnglishQ1860
P304page(s)7182-7188
P577publication date2009-05-01
P1433published inJournal of the American Chemical SocietyQ898902
P1476titleCyclic pyrrole-imidazole polyamides targeted to the androgen response element
P478volume131

Reverse relations

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