scholarly article | Q13442814 |
P50 | author | Peter Dervan | Q907746 |
Christian Dose | Q74956528 | ||
P2093 | author name string | John W Phillips | |
David M Chenoweth | |||
Daniel A Harki | |||
P2860 | cites work | A cell-permeable synthetic transcription factor mimic | Q79919848 |
Suppression of androgen receptor-mediated gene expression by a sequence-specific DNA-binding polyamide | Q24669875 | ||
Crystal structures of nucleosome core particles in complex with minor groove DNA-binding ligands | Q27640403 | ||
Structural basis for G.C recognition in the DNA minor groove | Q27748839 | ||
A structural basis for recognition of A.T and T.A base pairs in the minor groove of B-DNA | Q27765390 | ||
Recognition of the DNA minor groove by pyrrole-imidazole polyamides | Q28182798 | ||
Molecular recognition of DNA by small molecules | Q28216029 | ||
Pharmacokinetics in drug discovery | Q28236553 | ||
Recognition of the four Watson-Crick base pairs in the DNA minor groove by synthetic ligands | Q28261362 | ||
Recognition of DNA by designed ligands at subnanomolar concentrations | Q28284127 | ||
Cellular uptake of N-methylpyrrole/N-methylimidazole polyamide-dye conjugates | Q31099903 | ||
Nuclear localization of pyrrole–imidazole polyamide–fluorescein conjugates in cell culture | Q33193534 | ||
Improved nuclear localization of DNA-binding polyamides | Q33266897 | ||
Next generation hairpin polyamides with (R)-3,4-diaminobutyric acid turn unit | Q33331950 | ||
Quantitating the concentration of Py-Im polyamide-fluorescein conjugates in live cells | Q33340423 | ||
Completion of a Programmable DNA-Binding Small Molecule Library | Q33348532 | ||
Molecular recognition of the nucleosomal "supergroove". | Q33781158 | ||
Cyclic polyamides for recognition in the minor groove of DNA | Q33840166 | ||
Influence of structural variation on nuclear localization of DNA-binding polyamide-fluorophore conjugates | Q34334052 | ||
In vivo imaging of pyrrole-imidazole polyamides with positron emission tomography | Q36861667 | ||
Solution-phase synthesis of pyrrole-imidazole polyamides | Q37209301 | ||
Binding of a hairpin polyamide in the minor groove of DNA: sequence-specific enthalpic discrimination | Q37400189 | ||
Structural basis of androgen receptor binding to selective androgen response elements. | Q37414946 | ||
Inhibition of vascular endothelial growth factor with a sequence-specific hypoxia response element antagonist | Q37695740 | ||
Footprinting methods for analysis of pyrrole-imidazole polyamide/DNA complexes | Q38298047 | ||
NMR structure of a cyclic polyamide-DNA complex | Q38339789 | ||
Accessibility of Nuclear Chromatin by DNA Binding Polyamides | Q38349766 | ||
Modulating hypoxia-inducible transcription by disrupting the HIF-1-DNA interface | Q41857906 | ||
Sequence-specific recognition of DNA in the nucleosome by pyrrole-imidazole polyamides | Q43633078 | ||
Controlling the intracellular localization of fluorescent polyamide analogues in cultured cells | Q44406422 | ||
Synthesis of N-methylpyrrole and N-methylimidazole amino acids suitable for solid-phase synthesis | Q45139863 | ||
Discrimination of A/T sequences in the minor groove of DNA within a cyclic polyamide motif | Q46538655 | ||
Novel gene silencer pyrrole-imidazole polyamide targeting lectin-like oxidized low-density lipoprotein receptor-1 attenuates restenosis of the artery after injury | Q46562572 | ||
Development of gene silencing pyrrole-imidazole polyamide targeting the TGF-beta1 promoter for treatment of progressive renal diseases | Q46863385 | ||
Suppression of VEGF transcription in renal cell carcinoma cells by pyrrole-imidazole hairpin polyamides targeting the hypoxia responsive element. | Q54605056 | ||
Fmoc solid phase synthesis of polyamides containing pyrrole and imidazole amino acids | Q73868156 | ||
The thermodynamics of polyamide-DNA recognition: hairpin polyamide binding in the minor groove of duplex DNA | Q74456843 | ||
P433 | issue | 20 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 7182-7188 | |
P577 | publication date | 2009-05-01 | |
P1433 | published in | Journal of the American Chemical Society | Q898902 |
P1476 | title | Cyclic pyrrole-imidazole polyamides targeted to the androgen response element | |
P478 | volume | 131 |
Q38009888 | Androgen receptor antagonists: a patent review (2008-2011). |
Q38116575 | Androgen receptor modulators: a marriage of chemistry and biology |
Q36063723 | Androgen receptor: structure, role in prostate cancer and drug discovery |
Q37210876 | Animal toxicity of hairpin pyrrole-imidazole polyamides varies with the turn unit |
Q36339494 | Arrangement of Proteinogenic α-Amino Acids on a Cyclic Peptide Comprising Alternate Biphenyl-Cored ζ-Amino Acids. |
Q38076345 | Beyond the ligand-binding pocket: targeting alternate sites in nuclear receptors. |
Q41911133 | Binding of hairpin pyrrole and imidazole polyamides to DNA: relationship between torsion angle and association rate constants |
Q33717554 | Binding studies of a large antiviral polyamide to a natural HPV sequence. |
Q42034857 | Catch and Release DNA Decoys: Capture and Photochemical Dissociation of NF-κB Transcription Factors. |
Q36031605 | Characterization and solubilization of pyrrole-imidazole polyamide aggregates |
Q39624806 | Comparative Analysis of DNA-Binding Selectivity of Hairpin and Cyclic Pyrrole-Imidazole Polyamides Based on Next-Generation Sequencing. |
Q35617220 | Complexity in the binding of minor groove agents: netropsin has two thermodynamically different DNA binding modes at a single site. |
Q33710833 | Comprehensive survey of chemical libraries for drug discovery and chemical biology: 2009. |
Q51804811 | Conformational preferences of furan- and thiophene-based arylamides: a combined computational and experimental study. |
Q35823735 | Enhancing the cellular uptake of Py-Im polyamides through next-generation aryl turns |
Q35367751 | Expanding the repertoire of natural product-inspired ring pairs for molecular recognition of DNA. |
Q34421960 | Guiding the design of synthetic DNA-binding molecules with massively parallel sequencing |
Q40765155 | Interactions of two large antiviral polyamides with the long control region of HPV16. |
Q33720013 | Investigation and improvement of DNA cleavage models of polyamide + Cu(II) nuclease + OOH- ligands bound to DNA |
Q36002250 | Microwave assisted synthesis of Py-Im polyamides |
Q33780204 | Minireview: Not picking pockets: nuclear receptor alternate-site modulators (NRAMs) |
Q52659701 | New Opportunities for Targeting the Androgen Receptor in Prostate Cancer. |
Q34338685 | Noncanonical mechanisms to regulate nuclear receptor signaling |
Q37329318 | Oligomerization route to Py-Im polyamide macrocycles |
Q42217171 | Pyrrole-imidazole polyamides distinguish between double-helical DNA and RNA. |
Q34313126 | Replication stress by Py-Im polyamides induces a non-canonical ATR-dependent checkpoint response |
Q38310371 | Sequence-specific DNA recognition by cyclic pyrrole-imidazole cysteine-derived polyamide dimers. |
Q36275422 | Single-dose pharmacokinetic and toxicity analysis of pyrrole-imidazole polyamides in mice |
Q35598295 | Solution formulation development and efficacy of MJC13 in a preclinical model of castration-resistant prostate cancer |
Q27664249 | Structural Basis for Cyclic Py-Im Polyamide Allosteric Inhibition of Nuclear Receptor Binding |
Q37518681 | Structure-dependent inhibition of the ETS-family transcription factor PU.1 by novel heterocyclic diamidines |
Q34459196 | Synthesis of cyclic Py-Im polyamide libraries |
Q36749396 | Targeting a DNA binding motif of the EVI1 protein by a pyrrole-imidazole polyamide |
Q38924256 | The application of fluorescence-conjugated pyrrole/imidazole polyamides in the characterization of protein-DNA complex formation |
Q35842218 | Tumor Repression of VCaP Xenografts by a Pyrrole-Imidazole Polyamide |
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