Pharmacologically Counteracting a Phenotypic Difference in Cerebellar GABAA Receptor Response to Alcohol Prevents Excessive Alcohol Consumption in a High Alcohol-Consuming Rodent Genotype

scientific article published on August 2016

Pharmacologically Counteracting a Phenotypic Difference in Cerebellar GABAA Receptor Response to Alcohol Prevents Excessive Alcohol Consumption in a High Alcohol-Consuming Rodent Genotype is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1523/JNEUROSCI.0042-16.2016
P932PMC publication ID5005716
P698PubMed publication ID27581446

P50authorBen D RichardsonQ83379461
P2093author name stringMichelle A Nipper
David James Rossi
Deborah Ann Finn
Jeremiah Jensen
Josh Steven Kaplan
Melinda Helms
P2860cites workSpecialization of gene expression during mouse brain developmentQ21092512
Food reward, hyperphagia, and obesityQ24609658
Scheduled access alcohol drinking by alcohol-preferring (P) and high-alcohol-drinking (HAD) rats: modeling adolescent and adult binge-like drinkingQ27000166
A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010.Q27860879
Redefining the cerebellar cortex as an assembly of non-uniform Purkinje cell microcircuitsQ28083529
Opposite actions of alcohol on tonic GABA(A) receptor currents mediated by nNOS and PKC activityQ33616871
Alcohol-induced motor impairment caused by increased extrasynaptic GABA(A) receptor activityQ33787183
Molecular and behavioral aspects of the actions of alcohol on the adult and developing brainQ34191211
Mouse inbred strain differences in ethanol drinking to intoxication.Q34603439
Altered fronto-cerebellar connectivity in alcohol-naïve youth with a family history of alcoholismQ35148123
Molecular basis for the high THIP/gaboxadol sensitivity of extrasynaptic GABA(A) receptorsQ35326774
Effect of nucleus accumbens shell infusions of ganaxolone or gaboxadol on ethanol consumption in miceQ35546332
Cerebellar volume in offspring from multiplex alcohol dependence familiesQ35820311
Voluntary ethanol consumption in 22 inbred mouse strainsQ36676346
Impaired control over alcohol use: An under-addressed risk factor for problem drinking in young adults?Q36732134
Is autism a disease of the cerebellum? An integration of clinical and pre-clinical research.Q36833588
Consensus Paper: Cerebellar Development.Q36840256
Effect of ganaxolone and THIP on operant and limited-access ethanol self-administration.Q36851428
Neural Plasticity, Human Genetics, and Risk for Alcohol DependenceQ37021965
Primate cerebellar granule cells exhibit a tonic GABAAR conductance that is not affected by alcohol: a possible cellular substrate of the low level of response phenotype.Q37342572
Connecting the dots of the cerebro-cerebellar role in cognitive function: neuronal pathways for cerebellar modulation of dopamine release in the prefrontal cortex.Q37372356
Cerebellar modulation of frontal cortex dopamine efflux in mice: relevance to autism and schizophreniaQ37372557
Increased drinking during withdrawal from intermittent ethanol exposure is blocked by the CRF receptor antagonist D-Phe-CRF(12-41).Q48220534
PVN infusion of GLP-1-(7-36) amide suppresses feeding but does not induce aversion or alter locomotion in ratsQ48540815
Identification of genetic markers for initial sensitivity and rapid tolerance to ethanol-induced ataxia using quantitative trait locus analysis in BXD recombinant inbred miceQ48985680
Paleocerebellar stimulation induces in vivo release of endogenously synthesized [3H]dopamine and [3H]norepinephrine from rat caudal dorsomedial nucleus accumbensQ69159830
Ethanol-induced changes in body sway in men at high alcoholism riskQ70068801
P433issue35
P407language of work or nameEnglishQ1860
P921main subjectpharmacologyQ128406
alcohol consumptionQ2647488
P304page(s)9019-9025
P577publication date2016-08-01
P1433published inJournal of NeuroscienceQ1709864
P1476titlePharmacologically Counteracting a Phenotypic Difference in Cerebellar GABAA Receptor Response to Alcohol Prevents Excessive Alcohol Consumption in a High Alcohol-Consuming Rodent Genotype
P478volume36

Reverse relations

cites work (P2860)
Q47901530Alcohol and the Brain: Neuronal Molecular Targets, Synapses, and Circuits.
Q90315996Diverse types of genomic evidence converge on alcohol use disorder risk genes
Q38851626Recreational concentrations of alcohol enhance synaptic inhibition of cerebellar unipolar brush cells via pre- and postsynaptic mechanisms.
Q88599123The Cerebellar GABAAR System as a Potential Target for Treating Alcohol Use Disorder

Search more.