Functional disruption of the dystrophin gene in rhesus monkey using CRISPR/Cas9.

scientific article published on 09 April 2015

Functional disruption of the dystrophin gene in rhesus monkey using CRISPR/Cas9. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1093/HMG/DDV120
P932PMC publication ID5007610
P698PubMed publication ID25859012
P5875ResearchGate publication ID275227284

P50authorWeizhi JiQ44845569
P2093author name stringYongchang Chen
Hong Wang
Xiangyu Guo
Xiao-Jiang Li
Shihua Li
Yu Kang
Yinghui Zheng
Shang-Hsun Yang
Chenyang Si
Yuyu Niu
Ruxiao Xing
Weili Yang
Zhuchi Tu
Xiuqiong Pu
P2860cites workDevelopment and applications of CRISPR-Cas9 for genome engineeringQ28241526
X chromosome-linked muscular dystrophy (mdx) in the mouseQ28589078
One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineeringQ29547524
High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cellsQ29616045
Dystrophin: the protein product of the Duchenne muscular dystrophy locusQ29618077
Genetic engineering of human pluripotent cells using TALE nucleasesQ29619830
Timely translation during the mouse oocyte-to-embryo transition.Q30898601
TALEN-mediated gene mutagenesis in rhesus and cynomolgus monkeysQ33625156
Dystrophin and mutations: one gene, several proteins, multiple phenotypesQ34278933
Mammalian models of Duchenne Muscular Dystrophy: pathological characteristics and therapeutic applicationsQ34497055
The formation of skeletal muscle: from somite to limbQ35066903
Feline muscular dystrophy with dystrophin deficiencyQ35817354
The value of mammalian models for duchenne muscular dystrophy in developing therapeutic strategiesQ37383091
The paradox of muscle hypertrophy in muscular dystrophy.Q37975319
The medical genetics of dystrophinopathies: molecular genetic diagnosis and its impact on clinical practiceQ38057078
Generation of gene-modified cynomolgus monkey via Cas9/RNA-mediated gene targeting in one-cell embryos.Q39028341
Duchenne muscular dystrophy: Pathogenetic aspects and genetic preventionQ40170529
Generation of a monkey with MECP2 mutations by TALEN-based gene targetingQ41458178
Dystrophin-deficient mdx mice display a reduced life span and are susceptible to spontaneous rhabdomyosarcoma.Q51761621
The mdx mouse diaphragm reproduces the degenerative changes of Duchenne muscular dystrophyQ59051261
The homologue of the Duchenne locus is defective in X-linked muscular dystrophy of dogsQ59051983
An error in dystrophin mRNA processing in golden retriever muscular dystrophy, an animal homologue of Duchenne muscular dystrophyQ59416437
Dystrophin deficiency causes lethal muscle hypertrophy in catsQ68020670
Dystrophy-like myopathy in the catQ69549711
Muscle hypertrophy in Duchenne muscular dystrophy. A pathological and morphometric studyQ69943407
Skeletal muscle pathology in X chromosome-linked muscular dystrophy (mdx) mouseQ70039598
The mdx mouse skeletal muscle myopathy: I. A histological, morphometric and biochemical investigationQ70054992
Muscle development in mdx mutant miceQ70804155
The muscular dystrophiesQ77731754
P4510describes a project that usesCRISPR-Cas methodQ17310682
P433issue13
P921main subjectCRISPRQ412563
Cas9Q16965677
CRISPR-Cas methodQ17310682
P304page(s)3764-3774
P577publication date2015-04-09
P1433published inHuman Molecular GeneticsQ2720965
P1476titleFunctional disruption of the dystrophin gene in rhesus monkey using CRISPR/Cas9
P478volume24

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