The Changes of P-glycoprotein Activity by Interferon-γ and Tumor Necrosis Factor-α in Primary and Immortalized Human Brain Microvascular Endothelial Cells

scientific article published on May 2012

The Changes of P-glycoprotein Activity by Interferon-γ and Tumor Necrosis Factor-α in Primary and Immortalized Human Brain Microvascular Endothelial Cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.4062/BIOMOLTHER.2012.20.3.293
P932PMC publication ID3794526
P698PubMed publication ID24130926
P5875ResearchGate publication ID257840236

P2093author name stringPeter Rieckmann
Na-Young Lee
Young-Sook Kang
P2860cites workSynergistic activation of NF-kappaB by tumor necrosis factor alpha and gamma interferon via enhanced I kappaB alpha degradation and de novo I kappaBbeta degradationQ28571179
Transporters on demand: intrahepatic pools of canalicular ATP binding cassette transporters in rat liverQ31672347
Effect of tumor necrosis factor-alpha and interferon-gamma on intestinal P-glycoprotein expression, activity, and localization in Caco-2 cellsQ33202588
Synergistic action of pro-inflammatory agents: cellular and molecular aspects.Q33824865
Transporter-mediated permeation of drugs across the blood-brain barrierQ34051724
Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugsQ34059522
Molecular physiology and pathophysiology of tight junctions in the blood-brain barrierQ34446031
Micronutrient homeostasis in mammalian brain and cerebrospinal fluidQ38713141
Recent advances in blood-brain barrier transportQ39647214
Regulation of BCRP (ABCG2) and P-glycoprotein (ABCB1) by cytokines in a model of the human blood-brain barrierQ39821262
Rat brain vascular distribution of interleukin-1 type-1 receptor immunoreactivity: relationship to patterns of inducible cyclooxygenase expression by peripheral inflammatory stimuliQ40538176
Tumor necrosis factor-alpha (TNFalpha) regulates the epithelial barrier in the human intestinal cell line HT-29/B6.Q40990210
The blood-brain barrier and the inflammatory response.Q41576061
Synergy between interferon-gamma and tumor necrosis factor-alpha in transcriptional activation is mediated by cooperation between signal transducer and activator of transcription 1 and nuclear factor kappaB.Q42439020
Cytokine-regulated adhesion between encephalitogenic T lymphocytes and cerebrovascular endothelial cellsQ42497572
Interleukin 6 production in the central nervous system during experimental autoimmune encephalomyelitisQ43815260
Rapid regulation of P-glycoprotein at the blood-brain barrier by endothelin-1.Q45025173
Nitric oxide mediates increased P-glycoprotein activity in interferon-{gamma}-stimulated human intestinal cellsQ45108354
IFN-gamma down-regulates ABCA1 expression by inhibiting LXRalpha in a JAK/STAT signaling pathway-dependent mannerQ46370240
Influence of tumor necrosis factor-alpha on the expression and function of P-glycoprotein in an immortalised rat brain capillary endothelial cell line, GPNT.Q48231688
Tumor necrosis factor alpha and endothelin-1 increase P-glycoprotein expression and transport activity at the blood-brain barrierQ48355279
Selective expression of adhesion molecules on human brain microvascular endothelial cellsQ48697836
Rapid modulation of P-glycoprotein-mediated transport at the blood-brain barrier by tumor necrosis factor-alpha and lipopolysaccharideQ48702178
Reduced levels of antiinflammatory cytokines in patients with chronic widespread pain.Q54590339
Interferon-gamma up-regulates expression and activity of P-glycoprotein in human peripheral blood monocyte-derived macrophagesQ59491332
Influence of cytokines on mdr1 expression in human colon carcinoma cell lines: increased cytotoxicity of MDR relevant drugsQ72526525
Cytokine-induced modulation of cellular adhesion to human cerebral endothelial cells is mediated by soluble vascular cell adhesion molecule-1Q73585970
Effect of interferons on P-glycoprotein-mediated rhodamine-123 efflux in cultured rat hepatocytesQ74777568
TNF activates P-glycoprotein in cerebral microvascular endothelial cellsQ81550792
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectendotheliumQ111140
microvascular endothelial cellQ107137234
P304page(s)293-298
P577publication date2012-05-01
P1433published inBiomolecules & therapeuticsQ20020559
P1476titleThe Changes of P-glycoprotein Activity by Interferon-γ and Tumor Necrosis Factor-α in Primary and Immortalized Human Brain Microvascular Endothelial Cells
P478volume20

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cites work (P2860)
Q33655911A Novel Urotensin II Receptor Antagonist, KR-36996 Inhibits Smooth Muscle Proliferation through ERK/ROS Pathway
Q37235264Blockade of Urotensin II Receptor Prevents Vascular Dysfunction
Q41181941Chrysin Attenuates VCAM-1 Expression and Monocyte Adhesion in Lipopolysaccharide-Stimulated Brain Endothelial Cells by Preventing NF-κB Signaling
Q37301192Glutathione Depletion by L-Buthionine-S,R-Sulfoximine Induces Apoptosis of Cardiomyocytes through Activation of PKC-δ.
Q37286280Inhibitory Effect of an Urotensin II Receptor Antagonist on Proinflammatory Activation Induced by Urotensin II in Human Vascular Endothelial Cells
Q38844563Oxidative Stress Induced by Cigarette Smoke Extracts in Human Brain Cells (T98G) and Human Brain Microvascular Endothelial Cells (HBMEC) in Mono- and Co-Culture.
Q64948209RNA-seq analysis of blood of valproic acid-responsive and non-responsive pediatric patients with epilepsy.
Q38619057Transporter assays as useful in vitro tools in drug discovery and development

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