The biology and therapeutic potential of natural regulatory T-cells in the bone marrow transplant setting

scientific article published on October 2008

The biology and therapeutic potential of natural regulatory T-cells in the bone marrow transplant setting is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1080/10428190802272684
P698PubMed publication ID18661393

P50authorJonathan S. SerodyQ38327188
Timothy P MoranQ57011491
James M CoghillQ63136136
P2093author name stringMichael J Carlson
P2860cites workDisruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouseQ24290693
JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndromeQ24626901
Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3Q24672849
Clinical and molecular features of the immunodysregulation, polyendocrinopathy, enteropathy, X linked (IPEX) syndromeQ24679039
Control of regulatory T cell development by the transcription factor Foxp3Q27860489
Foxp3 programs the development and function of CD4+CD25+ regulatory T cellsQ27860714
Chemotherapy compared with autologous or allogeneic bone marrow transplantation in the management of acute myeloid leukemia in first remissionQ28290182
Cutting edge: TGF-beta induces a regulatory phenotype in CD4+CD25- T cells through Foxp3 induction and down-regulation of Smad7Q28591451
Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survivalQ29547865
CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cellsQ29618394
An essential role for Scurfin in CD4+CD25+ T regulatory cellsQ29618395
The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3Q29619324
CD4+CD25+ Immunoregulatory T Cells Suppress Polyclonal T Cell Activation In Vitro by Inhibiting Interleukin 2 ProductionQ29619536
Leukocyte migration and graft-versus-host diseaseQ30479618
Recipient-type specific CD4+CD25+ regulatory T cells favor immune reconstitution and control graft-versus-host disease while maintaining graft-versus-leukemiaQ33629928
An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammationQ33876035
Acute graft-vs-host disease: pathobiology and managementQ33940061
Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-toleranceQ34111451
CD4(+)CD25(+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptorQ34116317
Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4.Q34509694
Human T regulatory cells can use the perforin pathway to cause autologous target cell deathQ34551876
Suppression of natural killer cell-mediated bone marrow cell rejection by CD4+CD25+ regulatory T cellsQ34600272
Thymus and Reproduction: Sex-Linked Dysgenesia of the Gonad after Neonatal Thymectomy in MiceQ34705919
Chronic graft versus host diseaseQ35772587
Reduced frequency of FOXP3+ CD4+CD25+ regulatory T cells in patients with chronic graft-versus-host diseaseQ35848361
Critical role for CCR5 in the function of donor CD4+CD25+ regulatory T cells during acute graft-versus-host diseaseQ35848458
Reconstitution of FOXP3+ regulatory T cells (Tregs) after CD25-depleted allotransplantation in elderly patients and association with acute graft-versus-host disease.Q35989486
Regulatory functions of CD8+CD28– T cells in an autoimmune disease modelQ36001202
Acute graft versus host diseaseQ36059671
Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cellsQ36228688
Myeloid suppressor cells in cancer: recruitment, phenotype, properties, and mechanisms of immune suppressionQ36259867
Donor-type CD4(+)CD25(+) regulatory T cells suppress lethal acute graft-versus-host disease after allogeneic bone marrow transplantationQ36370863
In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetesQ36399048
CD4+CD25+ regulatory T cells inhibit natural killer cell functions in a transforming growth factor-beta-dependent mannerQ36403637
Graft-versus-host diseaseQ36793622
Large-scale in vitro expansion of polyclonal human CD4(+)CD25high regulatory T cells.Q40565739
Post-hematopoietic cell transplantation control of graft-versus-host disease by donor CD425 T cells to allow an effective graft-versus-leukemia responseQ40651436
CCR6 regulates the function of alloreactive and regulatory CD4+ T cells during acute graft-versus-host diseaseQ43449016
CD4+CD25+ regulatory T cells preserve graft-versus-tumor activity while inhibiting graft-versus-host disease after bone marrow transplantationQ44408941
Association of Foxp3 regulatory gene expression with graft-versus-host diseaseQ44917891
Cutting Edge: CD28 Controls Peripheral Homeostasis of CD4+CD25+ Regulatory T CellsQ46025217
A comparison of allogeneic and autologous bone marrow transplantation for lymphoblastic lymphomaQ47614903
L-Selectin(hi) but not the L-selectin(lo) CD4+25+ T-regulatory cells are potent inhibitors of GVHD and BM graft rejectionQ50796687
In vivo peripheral expansion of naive CD4+CD25high FoxP3+ regulatory T cells in patients with multiple myelomaQ51985543
Regulatory T-cells in the graft and the risk of acute graft-versus-host disease after allogeneic stem cell transplantationQ53557826
In vivo dynamics of regulatory T-cell trafficking and survival predict effective strategies to control graft-versus-host disease following allogeneic transplantationQ53589050
The expression of the regulatory T cell-specific forkhead box transcription factor FoxP3 is associated with poor prognosis in ovarian cancer.Q53646174
Immunosuppressive regulatory T cells are abundant in the reactive lymphocytes of Hodgkin lymphomaQ56903494
P433issue10
P921main subjectbone marrowQ546523
P304page(s)1860-1869
P577publication date2008-10-01
P13046publication type of scholarly workreview articleQ7318358
P1433published inLeukemia & LymphomaQ6534493
P1476titleThe biology and therapeutic potential of natural regulatory T-cells in the bone marrow transplant setting
P478volume49