The hepatitis E virus open reading frame 3 product interacts with microtubules and interferes with their dynamics

scientific article published on 15 April 2009

The hepatitis E virus open reading frame 3 product interacts with microtubules and interferes with their dynamics is …
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scholarly articleQ13442814

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P356DOI10.1128/JVI.02571-08
P932PMC publication ID2698551
P698PubMed publication ID19369329

P2093author name stringIoannis Bossis
Yan-Jin Zhang
Deendayal Patel
Harilakshmi Kannan
Sumin Fan
P2860cites workMolecular characterization of the 50-kD subunit of dynactin reveals function for the complex in chromosome alignment and spindle organization during mitosisQ24315967
The open reading frame 3 gene of hepatitis E virus contains a cis-reactive element and encodes a protein required for infection of macaquesQ24524173
Hepatitis E virus transmission from wild boar meatQ24610916
Inhibition of replication and transcription activator and latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus by morpholino oligomersQ27486093
Herpes simplex virus type 1 capsid protein VP26 interacts with dynein light chains RP3 and Tctex1 and plays a role in retrograde cellular transportQ28259269
Cytoplasmic dynein and LIS1 are required for microtubule advance during growth cone remodeling and fast axonal outgrowthQ28569366
Post-translational modifications regulate microtubule functionQ29036830
The ORF3 protein of hepatitis E virus binds to Src homology 3 domains and activates MAPK.Q30167985
Cytoplasmic dynein mediates adenovirus binding to microtubulesQ30448880
The ORF3 protein of hepatitis E virus interacts with liver-specific alpha1-microglobulin and its precursor alpha1-microglobulin/bikunin precursor (AMBP) and expedites their export from the hepatocyteQ33200018
The 41-amino-acid C-terminal region of the hepatitis E virus ORF3 protein interacts with bikunin, a kunitz-type serine protease inhibitorQ33222771
Hepatitis E virus (HEV): molecular cloning and sequencing of the full-length viral genomeQ33415661
Genetic and experimental evidence for cross-species infection by swine hepatitis E virusQ33786012
The dynein microtubule motorQ33866598
Recombinant hepatitis E virus genomes infectious for primates: importance of capping and discovery of a cis-reactive elementQ33953116
Solute and macromolecule diffusion in cellular aqueous compartmentsQ33956896
Genetic identification and characterization of a novel virus related to human hepatitis E virus from chickens with hepatitis-splenomegaly syndrome in the United StatesQ34091688
Intact microtubules support adenovirus and herpes simplex virus infectionsQ34347524
Neuritic transport of herpes simplex virus in rat sensory neurons in vitro. Effects of substances interacting with microtubular function and axonal flow [nocodazole, taxol and erythro-9-3-(2-hydroxynonyl)adenine].Q34387862
A novel virus in swine is closely related to the human hepatitis E virusQ34437217
A bicistronic subgenomic mRNA encodes both the ORF2 and ORF3 proteins of hepatitis E virusQ34651218
Initiation at the third in-frame AUG codon of open reading frame 3 of the hepatitis E virus is essential for viral infectivity in vivoQ35784950
MAP 1C is a microtubule-activated ATPase which translocates microtubules in vitro and has dynein-like propertiesQ36217545
Microtubule-dependent plus- and minus end-directed motilities are competing processes for nuclear targeting of adenovirusQ36255836
The ORF3 protein of hepatitis E virus is a phosphoprotein that associates with the cytoskeleton.Q36548587
The hepatitis E virus Orf3 protein protects cells from mitochondrial depolarization and death.Q36738014
The hepatitis E virus open reading frame 3 protein activates ERK through binding and inhibition of the MAPK phosphataseQ36739811
In vitro replication of hepatitis E virus (HEV) genomes and of an HEV replicon expressing green fluorescent proteinQ37422576
Identification of a novel microtubule binding and assembly domain in the developmentally regulated inter-repeat region of tau.Q38310577
African swine fever virus protein p54 interacts with the microtubular motor complex through direct binding to light-chain dynein.Q39604439
Role of microtubule-associated proteins in the control of microtubule assemblyQ40370781
Vaccinia virus infection disrupts microtubule organization and centrosome function.Q40392464
Zoonotic transmission of hepatitis E virus from deer to human beingsQ40569571
Monoclonal antibodies against conformationally dependent epitopes on porcine reproductive and respiratory syndrome virusQ40988966
A sensitive method for measuring polymerized and depolymerized forms of tubulin in tissuesQ41229629
Coupling cell division and cell death to microtubule dynamicsQ41678512
The phosphorylated form of the ORF3 protein of hepatitis E virus interacts with its non-glycosylated form of the major capsid protein, ORF2.Q42673813
Complete or near-complete nucleotide sequences of hepatitis E virus genome recovered from a wild boar, a deer, and four patients who ate the deerQ43218429
Sporadic acute or fulminant hepatitis E in Hokkaido, Japan, may be food-borne, as suggested by the presence of hepatitis E virus in pig liver as foodQ45722237
Effects of vanadate on the assembly and disassembly of purified tubulinQ48402530
Early events in the interaction of adenoviruses with HeLa cells. IV. Association with microtubules and the nuclear pore complex during vectorial movement of the inoculumQ64382838
P433issue13
P407language of work or nameEnglishQ1860
P921main subjecthepatitis E virusQ5731737
hepatitis EQ326643
P304page(s)6375-6382
P577publication date2009-04-15
P1433published inJournal of VirologyQ1251128
P1476titleThe hepatitis E virus open reading frame 3 product interacts with microtubules and interferes with their dynamics
P478volume83

Reverse relations

cites work (P2860)
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Q33630128Wsv023 interacted with Litopenaeus vannamei γ-tubulin complex associated proteins 2, and decreased the formation of microtubules.
Q46237020Zoonotic Hepatitis E Virus: An Ignored Risk for Public Health

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