review article | Q7318358 |
scholarly article | Q13442814 |
P2093 | author name string | Matthias Klugmann | |
Karen K Szumlinski | |||
P2860 | cites work | Mouse brain and muscle tissues constitutively express high levels of Homer proteins | Q73395510 |
Taurine blocks the glutamate increase in the nucleus accumbens microdialysate of ethanol-dependent rats | Q73444520 | ||
Prenatal and postnatal exposure to ethanol induces changes in the shape of the dendritic spines from hippocampal CA1 pyramidal neurons of the rat | Q73816066 | ||
Targeted retrograde gene delivery for neuronal protection | Q77474905 | ||
Differential control of postsynaptic density scaffolds via actin-dependent and -independent mechanisms | Q79948920 | ||
Surface clustering of metabotropic glutamate receptor 1 induced by long Homer proteins | Q21262045 | ||
Homer binds a novel proline-rich motif and links group 1 metabotropic glutamate receptors with IP3 receptors | Q22007971 | ||
Homer regulates the association of group 1 metabotropic glutamate receptors with multivalent complexes of homer-related, synaptic proteins | Q22008754 | ||
Shank, a novel family of postsynaptic density proteins that binds to the NMDA receptor/PSD-95/GKAP complex and cortactin | Q22010466 | ||
Homer Binds TRPC Family Channels and Is Required for Gating of TRPC1 by IP3 Receptors | Q24295021 | ||
Membrane-associated heparan sulfate proteoglycan is a receptor for adeno-associated virus type 2 virions | Q24531466 | ||
Structure of the Homer EVH1 domain-peptide complex reveals a new twist in polyproline recognition | Q27622377 | ||
Coupling of mGluR/Homer and PSD-95 complexes by the Shank family of postsynaptic density proteins | Q28141190 | ||
Homer 1b regulates the trafficking of group I metabotropic glutamate receptors | Q28143150 | ||
Inhibition of dendritic spine morphogenesis and synaptic transmission by activity-inducible protein Homer1a | Q28187839 | ||
Coincidence in dendritic clustering and synaptic targeting of homer proteins and NMDA receptor complex proteins NR2B and PSD95 during development of cultured hippocampal neurons | Q28188723 | ||
Rapid redistribution of the postsynaptic density protein PSD-Zip45 (Homer 1c) and its differential regulation by NMDA receptors and calcium channels. | Q43819953 | ||
Development and optimization of adeno-associated virus vector transfer into the central nervous system | Q43943045 | ||
Distribution of cystine/glutamate exchange transporter, system x(c)-, in the mouse brain. | Q44132586 | ||
Excitatory and inhibitory amino acid changes during repeated episodes of ethanol withdrawal: an in vivo microdialysis study | Q44275833 | ||
Synaptic targeting of PSD-Zip45 (Homer 1c) and its involvement in the synaptic accumulation of F-actin. | Q44276056 | ||
Effects of acamprosate on excitatory amino acids during multiple ethanol withdrawal periods. | Q44377070 | ||
Synaptic scaffolding protein Homer1a protects against chronic inflammatory pain | Q44385678 | ||
Prefrontal glutamate release into the core of the nucleus accumbens mediates cocaine-induced reinstatement of drug-seeking behavior. | Q44419020 | ||
Vesl/Homer proteins regulate ryanodine receptor type 2 function and intracellular calcium signaling | Q28190523 | ||
Homer regulates gain of ryanodine receptor type 1 channel complex | Q28201200 | ||
Agonist-independent activation of metabotropic glutamate receptors by the intracellular protein Homer | Q28202988 | ||
PI3 kinase enhancer–Homer complex couples mGluRI to PI3 kinase, preventing neuronal apoptosis | Q28207557 | ||
Tetrameric hub structure of postsynaptic scaffolding protein homer | Q28258271 | ||
Homer: a protein that selectively binds metabotropic glutamate receptors | Q28305877 | ||
Signaling complex formation of phospholipase Cbeta4 with metabotropic glutamate receptor type 1alpha and 1,4,5-trisphosphate receptor at the perisynapse and endoplasmic reticulum in the mouse brain | Q28511349 | ||
Novel members of the Vesl/Homer family of PDZ proteins that bind metabotropic glutamate receptors | Q28569381 | ||
The interaction of phospholipase C-beta3 with Shank2 regulates mGluR-mediated calcium signal | Q28574773 | ||
An N-terminal sequence specific for a novel Homer1 isoform controls trafficking of group I metabotropic glutamate receptor in mammalian cells | Q28584758 | ||
Homer proteins regulate sensitivity to cocaine | Q28587355 | ||
Cupidin, an isoform of Homer/Vesl, interacts with the actin cytoskeleton and activated rho family small GTPases and is expressed in developing mouse cerebellar granule cells | Q28590952 | ||
Mena, a relative of VASP and Drosophila Enabled, is implicated in the control of microfilament dynamics | Q28590972 | ||
Homer 2 tunes G protein-coupled receptors stimulus intensity by regulating RGS proteins and PLCbeta GAP activities | Q28592983 | ||
PDZ domain proteins of synapses | Q29616399 | ||
Pharmacology and functions of metabotropic glutamate receptors | Q29619150 | ||
Regulation of dendritic spine morphology and synaptic function by Shank and Homer | Q30014842 | ||
Homers regulate drug-induced neuroplasticity: implications for addiction | Q30491852 | ||
AAV vector-mediated RNAi of mutant huntingtin expression is neuroprotective in a novel genetic rat model of Huntington's disease | Q30549911 | ||
Synaptic activity-induced conversion of intronic to exonic sequence in Homer 1 immediate early gene expression. | Q30697805 | ||
Adeno-associated virus serotypes: vector toolkit for human gene therapy | Q33249130 | ||
Characterization of adeno-associated virus genomes isolated from human tissues | Q34142848 | ||
Gene therapy: trials and tribulations | Q34186665 | ||
Ethanol and NMDA receptor signaling | Q34186902 | ||
AAV8, 9, Rh10, Rh43 vector gene transfer in the rat brain: effects of serotype, promoter and purification method | Q34330377 | ||
Unmanageable motivation in addiction: a pathology in prefrontal-accumbens glutamate transmission | Q34400155 | ||
Viral-based gene transfer to the mammalian CNS for functional genomic studies | Q34446026 | ||
Association of a polymorphism in the Homer1 gene with cocaine dependence in an African American population. | Q34471095 | ||
Human fibroblast growth factor receptor 1 is a co-receptor for infection by adeno-associated virus 2. | Q34486856 | ||
AlphaVbeta5 integrin: a co-receptor for adeno-associated virus type 2 infection | Q34486863 | ||
Behavioral and neurochemical interactions between Group 1 mGluR antagonists and ethanol: potential insight into their anti-addictive properties. | Q34525273 | ||
Gene therapy for cystic fibrosis lung disease: current status and future perspectives | Q34578342 | ||
Aberrant synaptic activation of N-methyl-D-aspartate receptors underlies ethanol withdrawal hyperexcitability. | Q34603130 | ||
Psychomotor stimulant addiction: a neural systems perspective. | Q34616133 | ||
Neuroadaptations in cystine-glutamate exchange underlie cocaine relapse | Q44460612 | ||
Homer1 proteins and AMPA receptors modulate cocaine‐induced behavioural plasticity | Q44597465 | ||
Activity-inducible protein Homer1a/Vesl-1S promotes redistribution of postsynaptic protein Homer1c/Vesl-1L in cultured rat hippocampal neurons | Q44708409 | ||
Restoration of aspartoacylase activity in CNS neurons does not ameliorate motor deficits and demyelination in a model of Canavan disease. | Q44719583 | ||
Anticonvulsant and antiepileptogenic effects mediated by adeno-associated virus vector neuropeptide Y expression in the rat hippocampus. | Q44814719 | ||
Differential expression of Homer family proteins in the developing mouse brain | Q44873450 | ||
Recombinant AAV viral vectors pseudotyped with viral capsids from serotypes 1, 2, and 5 display differential efficiency and cell tropism after delivery to different regions of the central nervous system | Q45007196 | ||
Cocaine increases medial prefrontal cortical glutamate overflow in cocaine-sensitized rats: a time course study | Q45049931 | ||
Chronic ethanol induces synaptic but not extrasynaptic targeting of NMDA receptors. | Q45050785 | ||
Quantitative comparison of expression with adeno-associated virus (AAV-2) brain-specific gene cassettes. | Q45735544 | ||
In vivo transduction of cerebellar Purkinje cells using adeno-associated virus vectors | Q45739687 | ||
Strain differences in alcohol-induced neurochemical plasticity: a role for accumbens glutamate in alcohol intake | Q45743679 | ||
Quantitative analysis of the packaging capacity of recombinant adeno-associated virus | Q45766162 | ||
Recombinant AAV serotype 1 transduction efficiency and tropism in the murine brain | Q45864411 | ||
Influence of promoter and WHV post-transcriptional regulatory element on AAV-mediated transgene expression in the rat brain | Q45869654 | ||
Comparison of promoter strengths on gene delivery into mammalian brain cells using AAV vectors | Q45881872 | ||
Complex, multimodal behavioral profile of the Homer1 knockout mouse. | Q45990816 | ||
Regional differences in the effects of withdrawal from repeated cocaine upon Homer and glutamate receptor expression: a two-species comparison. | Q46010338 | ||
Accumbens neurochemical adaptations produced by binge-like alcohol consumption. | Q46032431 | ||
Prenatal stress alters limbo-corticostriatal Homer protein expression. | Q46036771 | ||
Ethanol exposure decreases glutamate uptake in the nucleus accumbens | Q46381488 | ||
Homer expression in the Xenopus tadpole nervous system | Q46463678 | ||
Key role of the postsynaptic density scaffold proteins Shank and Homer in the functional architecture of Ca2+ homeostasis at dendritic spines in hippocampal neurons. | Q46472740 | ||
Behavioral and neurochemical phenotyping of Homer1 mutant mice: possible relevance to schizophrenia. | Q46596359 | ||
Homer2 is necessary for EtOH-induced neuroplasticity. | Q46622590 | ||
Homer isoforms differentially regulate cocaine-induced neuroplasticity. | Q46701582 | ||
A novel role of circadian transcription factor DBP in hippocampal plasticity. | Q46780685 | ||
Homer interactions are necessary for metabotropic glutamate receptor-induced long-term depression and translational activation | Q46815693 | ||
Distinct roles for different Homer1 isoforms in behaviors and associated prefrontal cortex function. | Q46851475 | ||
A complex program of striatal gene expression induced by dopaminergic stimulation. | Q47892574 | ||
Isolation of PSD-Zip45, a novel Homer/vesl family protein containing leucine zipper motifs, from rat brain | Q48006881 | ||
Hippocampal gene expression profiling reveals the possible involvement of Homer1 and GABA(B) receptors in scopolamine-induced amnesia. | Q48150837 | ||
On the regional distribution of heparan sulfate proteoglycan immunoreactivity in the rat brain | Q48175852 | ||
Cocaine induces the expression of homer 1b/c, homer 3a/b, and hsp 27 proteins in rat cerebellum | Q48190511 | ||
In vivo regulation of Homer1a expression in the striatum by cocaine | Q48305377 | ||
Central effects of acamprosate: part 1. Acamprosate blocks the glutamate increase in the nucleus accumbens microdialysate in ethanol withdrawn rats | Q48386138 | ||
Conditional deletion of hypothalamic Y2 receptors reverts gonadectomy-induced bone loss in adult mice | Q48492969 | ||
Ibotenic acid lesions of the dorsal prefrontal cortex disrupt the expression of behavioral sensitization to cocaine | Q48534288 | ||
Homer-dependent cell surface expression of metabotropic glutamate receptor type 5 in neurons. | Q48563098 | ||
Dose and promoter effects of adeno-associated viral vector for green fluorescent protein expression in the rat brain | Q48563498 | ||
Interactions between ethanol and agents that act on the NMDA-type glutamate receptor | Q48874007 | ||
Effects of ethanol and anesthetics on type 1 and 5 metabotropic glutamate receptors expressed in Xenopus laevis oocytes | Q48947223 | ||
Repeated cocaine augments excitatory amino acid transmission in the nucleus accumbens only in rats having developed behavioral sensitization. | Q49116012 | ||
Signaling proteins in raft-like microdomains are essential for Ca2+ wave propagation in glial cells. | Q52572812 | ||
Acute ethanol increases taurine but neither glutamate nor GABA in the nucleus accumbens of male rats: a microdialysis study | Q72384610 | ||
Biphasic effect of ethanol on extracellular accumulation of glutamate in the hippocampus and the nucleus accumbens | Q72396807 | ||
Homer proteins regulate coupling of group I metabotropic glutamate receptors to N-type calcium and M-type potassium channels | Q73011082 | ||
Functional genomics and rat models | Q73198566 | ||
Dendritic and axonal targeting of type 5 metabotropic glutamate receptor is regulated by homer1 proteins and neuronal excitation | Q73258556 | ||
Up-regulation of cortical AMPA receptor binding in the fawn-hooded rat following ethanol withdrawal | Q73302793 | ||
Promoters and regulatory elements that improve adeno-associated virus transgene expression in the brain | Q34987192 | ||
Elevated levels of GluR1 in the midbrain: a trigger for sensitization to drugs of abuse? | Q35006478 | ||
Alcoholism: allostasis and beyond | Q35073089 | ||
Viral vectors for gene delivery to the nervous system | Q35120134 | ||
The genetics of adult-onset neuropsychiatric disease: complexities and conundra? | Q35573426 | ||
The Homer family and the signal transduction system at glutamatergic postsynaptic density: potential role in behavior and pharmacotherapy | Q35580028 | ||
NMDA receptor antagonism and the ethanol intoxication signal: from alcoholism risk to pharmacotherapy | Q35611019 | ||
Homer 1a uncouples metabotropic glutamate receptor 5 from postsynaptic effectors | Q35749646 | ||
Chronic alcohol drinking alters neuronal dendritic spines in the brain reward center nucleus accumbens | Q35762266 | ||
Cytogenetics and gene discovery in psychiatric disorders. | Q36019357 | ||
Recombinant adeno-associated viral vectors in the nervous system | Q36184768 | ||
Cloning of adeno-associated virus into pBR322: rescue of intact virus from the recombinant plasmid in human cells | Q36288360 | ||
Cortical mechanisms of cocaine sensitization | Q36523332 | ||
Dynamic regulation of ryanodine receptor type 1 (RyR1) channel activity by Homer 1 | Q36529038 | ||
NMDA receptors inhibit synapse unsilencing during brain development | Q36535421 | ||
Phosphorylation of glutamate receptors: a potential mechanism for the regulation of receptor function and psychostimulant action | Q36597439 | ||
Airway epithelium directed gene therapy for cystic fibrosis | Q36612211 | ||
Stable in vivo expression of the cystic fibrosis transmembrane conductance regulator with an adeno-associated virus vector | Q36663364 | ||
Involvement of unique leucine-zipper motif of PSD-Zip45 (Homer 1c/vesl-1L) in group 1 metabotropic glutamate receptor clustering | Q36702025 | ||
Adaptive plasticity of NMDA receptors and dendritic spines: implications for enhanced vulnerability of the adolescent brain to alcohol addiction | Q36732795 | ||
Molecular basis of genetic neuropsychiatric disorders | Q36846974 | ||
A recombinant plasmid from which an infectious adeno-associated virus genome can be excised in vitro and its use to study viral replication | Q36919184 | ||
Accumbens Homer2 overexpression facilitates alcohol-induced neuroplasticity in C57BL/6J mice | Q37398767 | ||
Woodchuck hepatitis virus contains a tripartite posttranscriptional regulatory element. | Q39580820 | ||
A key role for diacylglycerol lipase-alpha in metabotropic glutamate receptor-dependent endocannabinoid mobilization. | Q40116679 | ||
Homer 1 mediates store- and inositol 1,4,5-trisphosphate receptor-dependent translocation and retrieval of TRPC3 to the plasma membrane. | Q40247997 | ||
Adeno-associated virus vectors serotyped with AAV8 capsid are more efficient than AAV-1 or -2 serotypes for widespread gene delivery to the neonatal mouse brain | Q40329324 | ||
AAV-mediated hippocampal expression of short and long Homer 1 proteins differentially affect cognition and seizure activity in adult rats. | Q40462041 | ||
Hepatocyte growth factor receptor is a coreceptor for adeno-associated virus type 2 infection. | Q40726384 | ||
Homer-1c/Vesl-1L modulates the cell surface targeting of metabotropic glutamate receptor type 1alpha: evidence for an anchoring function | Q40901767 | ||
Enhanced expression of transgenes from adeno-associated virus vectors with the woodchuck hepatitis virus posttranscriptional regulatory element: implications for gene therapy | Q40924169 | ||
Co-expression of metabotropic glutamate receptor type 1alpha with homer-1a/Vesl-1S increases the cell surface expression of the receptor | Q40940136 | ||
The role of excitatory amino acids in behavioral sensitization to psychomotor stimulants | Q41749963 | ||
Generation and characterization of chimeric recombinant AAV vectors | Q41869331 | ||
The endocannabinoid system controls key epileptogenic circuits in the hippocampus | Q42065383 | ||
Ca2+ signaling in microdomains: Homer1 mediates the interaction between RyR2 and Cav1.2 to regulate excitation-contraction coupling | Q42170028 | ||
Long-term gene expression and phenotypic correction using adeno-associated virus vectors in the mammalian brain | Q42280576 | ||
Select overexpression of homer1a in dorsal hippocampus impairs spatial working memory | Q42401422 | ||
Chronic ethanol exposure leads to a selective enhancement of N-methyl-D-aspartate receptor function in cultured hippocampal neurons. | Q42448189 | ||
Homeostatic plasticity during alcohol exposure promotes enlargement of dendritic spines | Q42506908 | ||
HOMER2 binds MYO18B and enhances its activity to suppress anchorage independent growth | Q42829829 | ||
Characterization of a metabotropic glutamate receptor type 5-green fluorescent protein chimera (mGluR5-GFP): pharmacology, surface expression, and differential effects of Homer-1a and Homer-1c | Q43759581 | ||
Repeated cocaine administration attenuates group I metabotropic glutamate receptor-mediated glutamate release and behavioral activation: a potential role for Homer. | Q43792467 | ||
P433 | issue | 5-6 | |
P921 | main subject | lessons learned | Q1673259 |
P304 | page(s) | 485-500 | |
P577 | publication date | 2008-09-01 | |
P1433 | published in | Behavioural Pharmacology | Q15754239 |
P1476 | title | Targeting Homer genes using adeno-associated viral vector: lessons learned from behavioural and neurochemical studies | |
P478 | volume | 19 |
Q42826242 | AAV-Mediated Overexpression of the CB1 Receptor in the mPFC of Adult Rats Alters Cognitive Flexibility, Social Behavior, and Emotional Reactivity |
Q42402795 | Accumbens Homer2-mediated signaling: a factor contributing to mouse strain differences in alcohol drinking? |
Q42645980 | Altered surface mGluR5 dynamics provoke synaptic NMDAR dysfunction and cognitive defects in Fmr1 knockout mice. |
Q45998144 | Behavioral and Neurochemical Phenotyping of Mice Incapable of Homer1a Induction. |
Q37386920 | Binge drinking upregulates accumbens mGluR5-Homer2-PI3K signaling: functional implications for alcoholism |
Q44783539 | Cannabinoid exposure in pubertal rats increases spontaneous ethanol consumption and NMDA receptor associated protein levels. |
Q30367006 | Ethanol-Associated Changes in Glutamate Reward Neurocircuitry: A Minireview of Clinical and Preclinical Genetic Findings. |
Q36918187 | Functional regulation of PI3K-associated signaling in the accumbens by binge alcohol drinking in male but not female mice |
Q89824747 | Genomic analyses reveal distinct genetic architectures and selective pressures in buffaloes |
Q35142914 | Homer protein-metabotropic glutamate receptor binding regulates endocannabinoid signaling and affects hyperexcitability in a mouse model of fragile X syndrome. |
Q46468898 | Homer2 within the central nucleus of the amygdala modulates withdrawal-induced anxiety in a mouse model of binge-drinking |
Q36012581 | Homer2 within the nucleus accumbens core bidirectionally regulates alcohol intake by both P and Wistar rats |
Q42143920 | Homers at the Interface between Reward and Pain |
Q30447403 | Imbalances in prefrontal cortex CC-Homer1 versus CC-Homer2 expression promote cocaine preference |
Q39150830 | Methamphetamine Addiction Vulnerability: The Glutamate, the Bad, and the Ugly |
Q38267957 | MicroRNAs in Schizophrenia: Implications for Synaptic Plasticity and Dopamine-Glutamate Interaction at the Postsynaptic Density. New Avenues for Antipsychotic Treatment Under a Theranostic Perspective. |
Q46080683 | Nerve injury-induced changes in Homer/glutamate receptor signaling contribute to the development and maintenance of neuropathic pain |
Q27322939 | Overexpression of Homer1a in the basal and lateral amygdala impairs fear conditioning and induces an autism-like social impairment |
Q37923872 | Signaling pathways mediating alcohol effects. |
Q36084355 | Strong selection for behavioural resilience in Australian stock working dogs identified by selective sweep analysis |
Q30575221 | Synaptic depression via mGluR1 positive allosteric modulation suppresses cue-induced cocaine craving. |
Q39689904 | The pre-synaptic metabotropic glutamate receptor 7 "mGluR7" is a critical modulator of ethanol sensitivity in mice |
Q89964542 | Transgenic Analyses of Homer2 Function Within Nucleus Accumbens Subregions in the Regulation of Methamphetamine Reward and Reinforcement in Mice |
Q26864720 | Virogenetic and optogenetic mechanisms to define potential therapeutic targets in psychiatric disorders |
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