Parstatin: a cryptic peptide involved in cardioprotection after ischaemia and reperfusion injury

scientific article published on 20 April 2009

Parstatin: a cryptic peptide involved in cardioprotection after ischaemia and reperfusion injury is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/CVR/CVP122
P932PMC publication ID2701720
P698PubMed publication ID19380418
P5875ResearchGate publication ID24311275

P2093author name stringAnna Hsu
Jennifer L Strande
Jidong Su
John E Baker
Michael E Widlansky
JingLi Wang
Kasi V Routhu
Nikos E Tsopanoglou
P2860cites workNitric oxide directly activates calcium-dependent potassium channels in vascular smooth muscle.Q50773580
Opening of mitochondrial K(ATP) channels triggers the preconditioned state by generating free radicals.Q52024504
Preconditioning in immature rabbit hearts: role of KATP channels.Q52035110
Myogenic activation of canine small renal arteries after nonchemical removal of the endotheliumQ72101555
Increased tolerance of the chronically hypoxic immature heart to ischemia. Contribution of the KATP channelQ73120322
Ischemic preconditioning activates MAPKAPK2 in the isolated rabbit heart: evidence for involvement of p38 MAPKQ73427282
Phosphorylation of tyrosine 182 of p38 mitogen-activated protein kinase correlates with the protection of preconditioning in the rabbit heartQ73702803
Protease-activated receptor (PAR) 1 but not PAR2 or PAR4 mediates endothelium-dependent relaxation to thrombin and trypsin in human pulmonary arteriesQ74160974
Parstatin, the cleaved peptide on proteinase-activated receptor 1 activation, is a potent inhibitor of angiogenesisQ79802753
Ischemic preconditioning protects by activating prosurvival kinases at reperfusionQ80546877
Protease-activated receptor-2 activation causes EDHF-like coronary vasodilation: selective preservation in ischemia/reperfusion injury: involvement of lipoxygenase products, VR1 receptors, and C-fibersQ28580965
Hypoxia-induced preconditioning in adult stimulated cardiomyocytes is mediated by the opening and trafficking of sarcolemmal KATP channelsQ33201591
3'Phosphoinositide-dependent kinase-1 is essential for ischemic preconditioning of the myocardium.Q33262306
Inhibiting protease-activated receptor 4 limits myocardial ischemia/reperfusion injury in rat hearts by unmasking adenosine signalingQ34108989
NO stimulation of ATP-sensitive potassium channels: Involvement of Ras/mitogen-activated protein kinase pathway and contribution to neuroprotection.Q34337942
cGMP and S-nitrosylation: two routes for modulation of neuronal excitability by NO.Q34831503
The levosimendan metabolite OR-1896 elicits vasodilation by activating the K(ATP) and BK(Ca) channels in rat isolated arteriolesQ35546222
Impaired endothelium-dependent relaxation of dog coronary arteries after myocardial ischaemia and reperfusion: prevention by amlodipine, propranolol and allopurinolQ35872144
AMP-activated protein kinase mediates preconditioning in cardiomyocytes by regulating activity and trafficking of sarcolemmal ATP-sensitive K(+) channelsQ36247802
Reperfusion injury salvage kinase signalling: taking a RISK for cardioprotection.Q36836773
SCH 79797, a selective PAR1 antagonist, limits myocardial ischemia/reperfusion injury in rat heartsQ37617543
Protective effects of adenosine in the reversibly injured heartQ40484139
Acetylcholine leads to free radical production dependent on K(ATP) channels, G(i) proteins, phosphatidylinositol 3-kinase and tyrosine kinaseQ40713421
Potentiation by nitric oxide of the ATP-sensitive K+ current induced by K+ channel openers in guinea-pig ventricular cellsQ43170437
Levosimendan increases diastolic coronary flow in isolated guinea-pig heart by opening ATP-sensitive potassium channelsQ43573741
Relationship between no reflow and infarct size as influenced by the duration of ischemia and reperfusionQ43852730
The relative order of mK(ATP) channels, free radicals and p38 MAPK in preconditioning's protective pathway in rat heartQ44088321
Mechanism of thrombin-induced vasodilation in human coronary arteriolesQ44321359
Cardioprotective effects of acute and chronic opioid treatment are mediated via different signaling pathwaysQ44330669
Bradykinin induces mitochondrial ROS generation via NO, cGMP, PKG, and mitoKATP channel opening and leads to cardioprotectionQ44575126
Exogenous NO triggers preconditioning via a cGMP- and mitoKATP-dependent mechanismQ44814393
Phosphatidylinositol-3-kinase signaling is required for erythropoietin-mediated acute protection against myocardial ischemia/reperfusion injuryQ44875207
Cross-talk between the survival kinases during early reperfusion: its contribution to ischemic preconditioningQ44974883
Acetylcholine and bradykinin trigger preconditioning in the heart through a pathway that includes Akt and NOS.Q45032159
A role for thrombin receptor signaling in endothelial cells during embryonic developmentQ46345481
Inotropic, vasodilating and preconditioning actions of levosimendan in the heartQ46351998
Localizing extracellular signal-regulated kinase (ERK) in pharmacological preconditioning's trigger pathwayQ46800668
Protein S-nitrosylation: a role of nitric oxide signaling in cardiac ischemic preconditioning.Q46947186
Pertussis toxin abolishes the cardioprotective effect of ischemic preconditioning in intact rat heartQ47769993
The p38 MAPK inhibitor, SB203580, abrogates ischaemic preconditioning in rat heart but timing of administration is critical.Q50506897
Endotoxin-induced nonendothelial nitric oxide activates the Ca(2+)-activated K+ channel in cultured vascular smooth muscle cells.Q50768353
P433issue2
P921main subjectreperfusion injuryQ1413991
P304page(s)325-334
P577publication date2009-04-20
P1433published inCardiovascular ResearchQ4642329
P1476titleParstatin: a cryptic peptide involved in cardioprotection after ischaemia and reperfusion injury
P478volume83

Reverse relations

cites work (P2860)
Q37685882Anti-Parstatin Promotes Angiogenesis and Ameliorates Left Ventricular Dysfunction during Pressure Overload
Q34082171Cardioprotection from ischemia-reperfusion injury by near-infrared light in rats
Q41987407Nerve growth factor reduces myocardial ischemia/reperfusion injury in rat hearts.
Q30513467Nitric oxide synthase-dependent vasodilation of human subcutaneous arterioles correlates with noninvasive measurements of endothelial function
Q44305776Parstatin prevents renal injury following ischemia/reperfusion and radiocontrast administration.
Q33824563Parstatin, a novel protease-activated receptor 1-derived inhibitor of angiogenesis
Q35064542Protease-activated receptors and myocardial infarction
Q52888065The protease-activated receptor 1 possesses a functional and cleavable signal peptide which is necessary for receptor expression.