Crystallization and preliminary crystallographic studies of the single-chain variable fragment of antibody chA21 in complex with an N-terminal fragment of ErbB2.

scientific article published on 27 June 2009

Crystallization and preliminary crystallographic studies of the single-chain variable fragment of antibody chA21 in complex with an N-terminal fragment of ErbB2. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1107/S1744309109020107
P932PMC publication ID2705636
P698PubMed publication ID19574641
P5875ResearchGate publication ID26338148

P2093author name stringYang Liu
Maikun Teng
Jing Liu
Yongxiang Gao
Liwen Niu
Juanjuan Zhu
Huihao Zhou
P2860cites workInhibition of tumor growth by a monoclonal antibody reactive with an oncogene-encoded tumor antigenQ24628627
Structure of the extracellular region of HER2 alone and in complex with the Herceptin FabQ27640593
The crystal structure of a truncated ErbB2 ectodomain reveals an active conformation, poised to interact with other ErbB receptorsQ27640631
Epitope mapping and structural analysis of an anti-ErbB2 antibody A21: Molecular basis for tumor inhibitory mechanismQ27648036
Cell signaling by receptor tyrosine kinasesQ27860474
The CCP4 suite: programs for protein crystallographyQ27861090
An open-and-shut case? Recent insights into the activation of EGF/ErbB receptorsQ28207289
Purification and characterization of a single-chain chimeric anti-p185 antibody expressed by CHO-GS systemQ33213443
Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complexQ34314489
The ErbB receptors and their role in cancer progression.Q35089324
Receptor tyrosine kinases: mechanisms of activation and signalingQ36738608
Interaction of antibodies with ErbB receptor extracellular regionsQ37320814
Characterization and utilization of two novel anti-erbB-2 monoclonal antibodies in detection of soluble ErbB-2 for breast cancer prognosisQ42802846
The neu oncogene encodes an epidermal growth factor receptor-related proteinQ42812960
A survey of protein-protein complex crystallizationsQ44412407
Construction, expression and characterization of the engineered antibody against tumor surface antigen, p185(c-erbB-2).Q51838845
[Soluble expression and characterization of disulfide bond-rich subdomains of membrane protein p185 in Escherichia coli].Q54478621
Development of herceptinQ81353905
P433issuePt 7
P304page(s)692-694
P577publication date2009-06-27
P1433published inActa Crystallographica Section F: Structural Biology CommunicationsQ1924863
P1476titleCrystallization and preliminary crystallographic studies of the single-chain variable fragment of antibody chA21 in complex with an N-terminal fragment of ErbB2.
P478volume65

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cites work (P2860)
Q34128501Augmented inhibition of angiogenesis by combination of HER2 antibody chA21 and trastuzumab in human ovarian carcinoma xenograft
Q39630334In vivo activity of novel anti-ErbB2 antibody chA21 alone and with Paclitaxel or Trastuzumab in breast and ovarian cancer xenograft models
Q27670462Structural Insights into the Down-regulation of Overexpressed p185her2/neu Protein of Transformed Cells by the Antibody chA21

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