Milk oligosaccharide sialyl(α2,3)lactose activates intestinal CD11c+ cells through TLR4

scientific article published on 07 October 2013

Milk oligosaccharide sialyl(α2,3)lactose activates intestinal CD11c+ cells through TLR4 is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2013PNAS..11017444K
P356DOI10.1073/PNAS.1306322110
P932PMC publication ID3808656
P698PubMed publication ID24101501
P5875ResearchGate publication ID257531323

P50authorLubor BorsigQ39051976
Gerhard RoglerQ64750687
P2093author name stringMartin Hausmann
Thierry Hennet
Ekaterina Kurakevich
P2860cites workIncreasing Incidence and Prevalence of the Inflammatory Bowel Diseases With Time, Based on Systematic ReviewQ22250934
Sialic acid utilization by bacterial pathogensQ28244449
TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cellsQ28296956
Mycobacteria target DC-SIGN to suppress dendritic cell functionQ28616857
Interleukin-10-deficient mice develop chronic enterocolitisQ29547881
A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanismQ29614266
Genetics and pathogenesis of inflammatory bowel diseaseQ29616350
Intestinal epithelial cell up-regulation of LY6 molecules during colitis results in enhanced chemokine secretionQ33322650
Sialyltransferase ST3Gal-IV operates as a dominant modifier of hemostasis by concealing asialoglycoprotein receptor ligandsQ33343091
Toll-like receptors activate innate and adaptive immunity by using dendritic cell-intrinsic and -extrinsic mechanismsQ33762668
Dietary modulation of the human colonic microbiota: updating the concept of prebioticsQ34015209
The human milk oligosaccharide disialyllacto-N-tetraose prevents necrotising enterocolitis in neonatal ratsQ34090141
TLR signaling in the gut in health and diseaseQ34409408
Milk sialyllactose influences colitis in mice through selective intestinal bacterial colonization.Q34420808
Intestinal lamina propria dendritic cell subsets have different origin and functions.Q35001346
Host-derived sialic acid is incorporated into Haemophilus influenzae lipopolysaccharide and is a major virulence factor in experimental otitis mediaQ35171126
Inflammation switches the differentiation program of Ly6Chi monocytes from antiinflammatory macrophages to inflammatory dendritic cells in the colon.Q35679555
Dendritic cells in intestinal immune regulation.Q37171796
Role of mucosal dendritic cells in inflammatory bowel diseaseQ37263002
Role of diet in the development of inflammatory bowel diseaseQ37492475
Human milk oligosaccharides: prebiotics and beyondQ37631126
Current trends in the structure-activity relationships of sialyltransferasesQ37811693
Glycan recognition at the interface of the intestinal immune system: target for immune modulation via dietary components.Q37911574
Campylobacter jejuni lipooligosaccharides modulate dendritic cell-mediated T cell polarization in a sialic acid linkage-dependent mannerQ38335835
TLR4-mediated sensing of Campylobacter jejuni by dendritic cells is determined by sialylationQ39696457
Population-based cases control study of inflammatory bowel disease risk factors.Q39914957
Intestinal CD103+, but not CX3CR1+, antigen sampling cells migrate in lymph and serve classical dendritic cell functions.Q42138485
The schistosome oligosaccharide lacto-N-neotetraose expands Gr1(+) cells that secrete anti-inflammatory cytokines and inhibit proliferation of naive CD4(+) cells: a potential mechanism for immune polarization in helminth infectionsQ43427795
Rectal prolapse and fecal incontinence.Q50537791
An independent subset of TLR expressing CCR2-dependent macrophages promotes colonic inflammation.Q54427475
Intestinal Tolerance Requires Gut Homing and Expansion of FoxP3+ Regulatory T Cells in the Lamina PropriaQ57339886
P433issue43
P407language of work or nameEnglishQ1860
P921main subjectoligosaccharideQ320607
toll-like receptorQ408004
P1104number of pages6
P304page(s)17444-17449
P577publication date2013-10-07
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleMilk oligosaccharide sialyl(α2,3)lactose activates intestinal CD11c+ cells through TLR4
P478volume110

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cites work (P2860)
Q35951256Annotation of porcine milk oligosaccharides throughout lactation by hydrophilic interaction chromatography coupled with quadruple time of flight tandem mass spectrometry.
Q34421404Carbohydrate intake in the etiology of Crohn's disease and ulcerative colitis
Q50320976Cow's Milk and Immune Function in the Respiratory Tract: Potential Mechanisms
Q40206940Dietary Human Milk Oligosaccharides but Not Prebiotic Oligosaccharides Increase Circulating Natural Killer Cell and Mesenteric Lymph Node Memory T Cell Populations in Noninfected and Rotavirus-Infected Neonatal Piglets
Q27011839Food allergies: the basics
Q38211778Functional role and mechanisms of sialyllactose and other sialylated milk oligosaccharides
Q37585321Handling stress may confound murine gut microbiota studies
Q38698319Human Milk Components Modulate Toll-Like Receptor-Mediated Inflammation
Q39095261Human Milk Oligosaccharides Influence Neonatal Mucosal and Systemic Immunity.
Q92549726Human milk oligosaccharides promote immune tolerance via direct interactions with human dendritic cells
Q64915671Immunological Effects of Human Milk Oligosaccharides.
Q95840991Immunomodulation by Human Milk Oligosaccharides: The Potential Role in Prevention of Allergic Diseases
Q35684219In Vitro Evidence for Immune-Modulatory Properties of Non-Digestible Oligosaccharides: Direct Effect on Human Monocyte Derived Dendritic Cells
Q49557750Induction of human tolerogenic dendritic cells by 3'-sialyllactose via TLR4 is explained by LPS contamination.
Q52714627Lactose Induces Phenotypic and Functional Changes of Neutrophils and Macrophages to Alleviate Acute Pancreatitis in Mice.
Q34553668Lactose inhibits regulatory T-cell-mediated suppression of effector T-cell interferon-γ and IL-17 production
Q33799038Milk oligosaccharides over time of lactation from different dog breeds
Q47276804Prebiotic Oligosaccharides Potentiate Host Protective Responses against L. Monocytogenes Infection
Q35754002Sialic acid catabolism drives intestinal inflammation and microbial dysbiosis in mice.
Q64260228Sialylated Oligosaccharides and Glycoconjugates of Human Milk. The Impact on Infant and Newborn Protection, Development and Well-Being
Q64890583Synthesis and Characterization of Sialylated Lactose- and Lactulose-Derived Oligosaccharides by Trypanosoma cruzi Trans-sialidase.
Q26783621The Role of Immunonutrients in the Prevention of Necrotizing Enterocolitis in Preterm Very Low Birth Weight Infants
Q89498378The oligosaccharides 6'-sialyllactose, 2'-fucosyllactose or galactooligosaccharides do not directly modulate human dendritic cell differentiation or maturation
Q36514964Urine Metabolite Profiles Predictive of Human Kidney Allograft Status

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