An integrative and comparative study of pan-cancer transcriptomes reveals distinct cancer common and specific signatures

scientific article published on 16 September 2016

An integrative and comparative study of pan-cancer transcriptomes reveals distinct cancer common and specific signatures is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/SREP33398
P932PMC publication ID5025752
P698PubMed publication ID27633916

P2093author name stringShihua Zhang
Zhen Cao
P2860cites workHallmarks of Cancer: The Next GenerationQ22252312
Cell cycle, CDKs and cancer: a changing paradigmQ24314465
The Cancer Genome Atlas Pan-Cancer analysis projectQ24606808
A scaling normalization method for differential expression analysis of RNA-seq dataQ24628783
Comprehensive molecular characterization of human colon and rectal cancerQ24630415
Comprehensive molecular portraits of human breast tumoursQ24630844
GeneMANIA: a real-time multiple association network integration algorithm for predicting gene functionQ24646439
Nonparametric Estimation from Incomplete ObservationsQ25938997
Integrated genomic analyses of ovarian carcinomaQ27860518
edgeR: a Bioconductor package for differential expression analysis of digital gene expression dataQ27860819
Missing value estimation methods for DNA microarraysQ28200763
Cell cycle kinases as therapeutic targets for cancerQ28250447
Triple-Negative Breast CancerQ29391607
TRANSFAC: transcriptional regulation, from patterns to profilesQ29547394
Evaluation of statistical methods for normalization and differential expression in mRNA-Seq experimentsQ29614452
Supervised risk predictor of breast cancer based on intrinsic subtypesQ29617404
Molecular cytogenetics of renal cell tumorsQ40715328
Independent component analysis uncovers the landscape of the bladder tumor transcriptome and reveals insights into luminal and basal subtypesQ41747556
Pancancer analysis of DNA methylation-driven genes using MethylMixQ42237233
Low methylation levels of the SFRP1 gene are associated with the basal-like subtype of breast cancerQ42435258
HBx gene of hepatitis B virus induces liver cancer in transgenic miceQ45852802
Gene expression analysis identifies global gene dosage sensitivity in cancer.Q48236292
Finding community structure in networks using the eigenvectors of matrices.Q51931750
Comparative pan-cancer DNA methylation analysis reveals cancer common and specific patterns.Q54777296
Renal cell carcinomaQ56019530
BRAF mutations are associated with some histological types of papillary thyroid carcinomaQ60527136
Cancer cachexiaQ68149864
pS2 (TFF1) levels in human breast cancer tumor samples: correlation with clinical and histological prognostic markersQ73207847
The estrogen-regulated protein, TFF1, stimulates migration of human breast cancer cellsQ77835923
limma powers differential expression analyses for RNA-sequencing and microarray studiesQ29617988
Primary liver cancer: worldwide incidence and trendsQ29620133
Intra-tumour heterogeneity: a looking glass for cancer?Q29620149
A comprehensive evaluation of normalization methods for Illumina high-throughput RNA sequencing data analysisQ30567356
Integration of genomic data enables selective discovery of breast cancer drivers.Q30872438
Coexpression analysis of human genes across many microarray data setsQ30936126
GeneMANIA Cytoscape plugin: fast gene function predictions on the desktopQ33711706
Toward a systematic understanding of cancers: a survey of the pan-cancer studyQ33840041
A pan-cancer proteomic perspective on The Cancer Genome Atlas.Q33944976
Multiplatform analysis of 12 cancer types reveals molecular classification within and across tissues of originQ34123261
Identifying multi-layer gene regulatory modules from multi-dimensional genomic dataQ34366411
Weighted frequent gene co-expression network mining to identify genes involved in genome stabilityQ34407753
Novel approaches in the therapy of metastatic renal cell carcinoma.Q34409187
Interaction between TFF1, a gastric tumor suppressor trefoil protein, and TFIZ1, a brichos domain-containing protein with homology to SP-C.Q34422380
DNA methylation signatures identify biologically distinct subtypes in acute myeloid leukemia.Q34433577
Cancer cachexia: mechanisms and clinical implicationsQ34631019
Mammalian cell-cycle regulation: several Cdks, numerous cyclins and diverse compensatory mechanisms.Q34989521
Emerging landscape of oncogenic signatures across human cancersQ35058708
g:Profiler--a web server for functional interpretation of gene lists (2011 update).Q35075627
Deficiency in trefoil factor 1 (TFF1) increases tumorigenicity of human breast cancer cells and mammary tumor development in TFF1-knockout mice.Q35120439
Tumor characterization and stratification by integrated molecular profiles reveals essential pan-cancer featuresQ35684524
Chromosomal imbalances in papillary renal cell carcinoma: genetic differences between histological subtypesQ35754544
Network-based survival-associated module biomarker and its crosstalk with cell death genes in ovarian cancerQ35769650
Subtype and pathway specific responses to anticancer compounds in breast cancerQ35779241
An integrative pan-cancer-wide analysis of epigenetic enzymes reveals universal patterns of epigenomic deregulation in cancerQ35848254
Roles of RAS and BRAF mutations in thyroid carcinogenesis.Q36429261
Molecular bases of cell-cell junctions stability and dynamicsQ37672322
Collagen as a double-edged sword in tumor progressionQ37692855
Molecular pathways of urothelial development and bladder tumorigenesisQ37770779
Origins of aberrant DNA methylation in acute myeloid leukemiaQ38130091
The extracellular matrix modulates the hallmarks of cancerQ38266276
Sp1 and the 'hallmarks of cancer'.Q38267908
Influence of secreted frizzled receptor protein 1 (SFRP1) on neoadjuvant chemotherapy in triple negative breast cancer does not rely on WNT signalingQ38974592
Gene co-expression analysis identifies common modules related to prognosis and drug resistance in cancer cell lines.Q39000867
Pan-cancer analysis of the extent and consequences of intratumor heterogeneity.Q40139573
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that useslimmaQ112236343
edgeRQ113334690
P407language of work or nameEnglishQ1860
P921main subjecttranscriptomeQ252857
P304page(s)33398
P577publication date2016-09-16
P1433published inScientific ReportsQ2261792
P1476titleAn integrative and comparative study of pan-cancer transcriptomes reveals distinct cancer common and specific signatures
P478volume6

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cites work (P2860)
Q90171142Edgetic perturbation signatures represent known and novel cancer biomarkers
Q92000742NCAPG Is a Promising Therapeutic Target Across Different Tumor Types
Q47193672Optimizing prognosis-related key miRNA-target interactions responsible for cancer metastasis
Q52718930Pan-cancer analysis of somatic mutations and transcriptomes reveals common functional gene clusters shared by multiple cancer types.
Q89456670Pathogenic mutations and overall survival in 3,084 patients with cancer: the Hellenic Cooperative Oncology Group Precision Medicine Initiative

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