LECT2 drives haematopoietic stem cell expansion and mobilization via regulating the macrophages and osteolineage cells.

scientific article published on 06 September 2016

LECT2 drives haematopoietic stem cell expansion and mobilization via regulating the macrophages and osteolineage cells. is …
instance of (P31):
scholarly articleQ13442814

External links are
P819ADS bibcode2016NatCo...712719L
P356DOI10.1038/NCOMMS12719
P932PMC publication ID5025878
P698PubMed publication ID27596364

P50authorXin-Jiang LuQ88268016
P2093author name stringQiang Chen
Jiong Chen
Chao-Hui Yu
Hui-Ying Wang
Shun Zhang
Ye-Jing Rong
Yu-Hong Shi
Chang-Hong Li
Guan-Jun Yang
Ning-Yi Xu
P2860cites workHematopoietic stem cell transplantation for HIV cureQ36515124
LECT2 protects mice against bacterial sepsis by activating macrophages via the CD209a receptorQ36547685
PAR1 signaling regulates the retention and recruitment of EPCR-expressing bone marrow hematopoietic stem cellsQ36647485
Therapeutic targeting and rapid mobilization of endosteal HSC using a small molecule integrin antagonistQ36698963
Intrinsic and extrinsic control of haematopoietic stem-cell self-renewalQ37164036
Mesenchymal cell contributions to the stem cell nicheQ38369890
Heparan sulfate/heparin oligosaccharides protect stromal cell-derived factor-1 (SDF-1)/CXCL12 against proteolysis induced by CD26/dipeptidyl peptidase IV.Q40528868
G-CSF induces stem cell mobilization by decreasing bone marrow SDF-1 and up-regulating CXCR4.Q40724468
Hepatocyte growth factor is secreted by osteoblasts and cooperatively permits the survival of haematopoietic progenitors.Q40828878
Bone Marrow Macrophages Contribute to Diabetic Stem Cell Mobilopathy by Producing Oncostatin M.Q41169174
Identification and characterization of an inhibitor of haemopoietic stem cell proliferation.Q41740025
Tumor necrosis factor restricts hematopoietic stem cell activity in mice: involvement of two distinct receptorsQ42018205
Megakaryocytes maintain homeostatic quiescence and promote post-injury regeneration of hematopoietic stem cells.Q42775682
Haematopoietic ESL-1 enables stem cell proliferation in the bone marrow by limiting TGFβ availabilityQ43065235
IFNalpha activates dormant haematopoietic stem cells in vivo.Q44358922
Characterization and outcomes of renal leukocyte chemotactic factor 2-associated amyloidosisQ46108501
LECT2 makes the amyloid listQ46239329
An endotoxin-induced serum factor that causes necrosis of tumorsQ24564406
Inflammatory modulation of HSCs: viewing the HSC as a foundation for the immune responseQ27003372
Proinflammatory signaling regulates hematopoietic stem cell emergence.Q27324011
The hematopoietic stem cell niche in homeostasis and diseaseQ28082775
Purification and primary amino acid sequence of a novel neutrophil chemotactic factor LECT2Q28115395
How I treat patients who mobilize hematopoietic stem cells poorlyQ28245316
Targeted disruption of the biglycan gene leads to an osteoporosis-like phenotype in miceQ28281780
Five mouse homologues of the human dendritic cell C-type lectin, DC-SIGNQ28589720
Osteoblastic cells regulate the haematopoietic stem cell nicheQ29615007
Signalling pathways of the TNF superfamily: a double-edged swordQ29616428
S1P promotes murine progenitor cell egress and mobilization via S1P1-mediated ROS signaling and SDF-1 releaseQ33595777
Quantitative assay for totipotent reconstituting hematopoietic stem cells by a competitive repopulation strategyQ33888454
Rhythmic modulation of the hematopoietic niche through neutrophil clearance.Q34026142
CD34 expression by murine hematopoietic stem cells. Developmental changes and kinetic alterationsQ34084180
Downregulation of Prdm16 mRNA is a specific antileukemic mechanism during HOXB4-mediated HSC expansion in vivoQ34170361
Rapid mobilization of hematopoietic progenitors by AMD3100 and catecholamines is mediated by CXCR4-dependent SDF-1 release from bone marrow stromal cellsQ34246928
Bone marrow CD169+ macrophages promote the retention of hematopoietic stem and progenitor cells in the mesenchymal stem cell nicheQ34577717
Expression of the G-CSF receptor in monocytic cells is sufficient to mediate hematopoietic progenitor mobilization by G-CSF in miceQ34577738
Microbial stimulation fully differentiates monocytes to DC-SIGN/CD209(+) dendritic cells for immune T cell areas.Q35148879
IP3 3-kinase B controls hematopoietic stem cell homeostasis and prevents lethal hematopoietic failure in miceQ35560031
Diabetes Limits Stem Cell Mobilization Following G-CSF but Not PlerixaforQ35881779
The bone marrow niche for haematopoietic stem cellsQ35887876
Critical role of macrophages in the marginal zone in the suppression of immune responses to apoptotic cell-associated antigensQ35901015
Clinical strategies for expansion of haematopoietic stem cellsQ35934167
Human osteoblasts support hematopoiesis through the production of granulocyte colony-stimulating factor.Q36363179
A dominant complement fixation pathway for pneumococcal polysaccharides initiated by SIGN-R1 interacting with C1q.Q51808487
The tumor suppressor function of LECT2 in human hepatocellular carcinoma makes it a potential therapeutic target.Q53262009
Fms-like tyrosine kinase 3 (Flt3) ligand depletes erythroid island macrophages and blocks medullar erythropoiesis in the mouse.Q53263838
Strontium can increase some osteoblasts without increasing hematopoietic stem cells.Q53519157
LECT2 functions as a hepatokine that links obesity to skeletal muscle insulin resistance.Q54381103
Bone marrow macrophages maintain hematopoietic stem cell (HSC) niches and their depletion mobilizes HSCs.Q54415335
Monocytes-macrophages that express α-smooth muscle actin preserve primitive hematopoietic cells in the bone marrow.Q54483270
CD34 Expression by Murine Hematopoietic Stem CellsQ56551909
Diphtheria toxin receptor–mediated conditional and targeted cell ablation in transgenic miceQ60017797
Leukocyte cell-derived chemotaxin 2 antagonizes MET receptor activation to suppress hepatocellular carcinoma vascular invasion by protein tyrosine phosphatase 1B recruitmentQ62559525
Reversible expression of CD34 by murine hematopoietic stem cellsQ73070185
Cell surface peptidase CD26/DPPIV mediates G-CSF mobilization of mouse progenitor cellsQ78952597
Modulation of hematopoietic stem cell homing and engraftment by CD26Q80450248
Impact of different strategies of second-line stem cell harvest on the outcome of autologous transplantation in poor peripheral blood stem cell mobilizersQ81093833
Genetic regulation of hematopoietic stem cell exhaustion during development and growthQ81330310
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P304page(s)12719
P577publication date2016-09-06
P1433published inNature CommunicationsQ573880
P1476titleLECT2 drives haematopoietic stem cell expansion and mobilization via regulating the macrophages and osteolineage cells
P478volume7

Reverse relations

cites work (P2860)
Q38788608CXCR3.1 and CXCR3.2 Differentially Contribute to Macrophage Polarization in Teleost Fish
Q34547149Cellular players of hematopoietic stem cell mobilization in the bone marrow niche.
Q90069593Cytokine-induced hematopoietic stem and progenitor cell mobilization: unraveling interactions between stem cells and their niche
Q39003470Extracellular molecules in hematopoietic stem cell mobilisation
Q39155573Latest perspectives on macrophages in bone homeostasis.
Q91918478Leukocyte cell-derived chemotaxin 2 inhibits development of atherosclerosis in mice
Q36380978Molecular characterization of mudskipper (Boleophthalmus pectinirostris) hypoxia-inducible factor-1α (HIF-1α) and analysis of its function in monocytes/macrophages

Search more.