From dual binding site acetylcholinesterase inhibitors to multi-target-directed ligands (MTDLs): a step forward in the treatment of Alzheimer's disease

scientific article published on September 2008

From dual binding site acetylcholinesterase inhibitors to multi-target-directed ligands (MTDLs): a step forward in the treatment of Alzheimer's disease is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.2174/138955708785740652
P698PubMed publication ID18782050

P50authorAnna MinariniQ57078501
P2093author name stringMaria Laura Bolognesi
Carlo Melchiorre
Michela Rosini
Vincenzo Tumiatti
P433issue10
P921main subjectAlzheimer's diseaseQ11081
P304page(s)960-967
P577publication date2008-09-01
P1433published inMini-Reviews in Medicinal ChemistryQ3314982
P1476titleFrom dual binding site acetylcholinesterase inhibitors to multi-target-directed ligands (MTDLs): a step forward in the treatment of Alzheimer's disease
P478volume8

Reverse relations

cites work (P2860)
Q92327129Alzheimer's Disease Pharmacotherapy in Relation to Cholinergic System Involvement
Q43172090Chemotherapeutic potential of 9-phenyl acridine: biophysical studies on its binding to DNA.
Q38022265Clinical utility of neuroprotective agents in neurodegenerative diseases: current status of drug development for Alzheimer's, Parkinson's and Huntington's diseases, and amyotrophic lateral sclerosis.
Q53182177Design, Synthesis and Evaluation of Hesperetin Derivatives as Potential Multifunctional Anti-Alzheimer Agents.
Q36004978Exploration of a Library of 3,4-(Methylenedioxy)aniline-Derived Semicarbazones as Dual Inhibitors of Monoamine Oxidase and Acetylcholinesterase: Design, Synthesis, and Evaluation.
Q42917723Inhibition of acetylcholinesterase by chromophore-linked fluorophosphonates
Q28820783Memoquin: a multi-target-directed ligand as an innovative therapeutic opportunity for Alzheimer's disease
Q38184970Multi-target design strategies in the context of Alzheimer's disease: acetylcholinesterase inhibition and NMDA receptor antagonism as the driving forces
Q43151006Nantenine as an acetylcholinesterase inhibitor: SAR, enzyme kinetics and molecular modeling investigations.
Q47253553Synthesis and bioevaluation of new tacrine-cinnamic acid hybrids as cholinesterase inhibitors against Alzheimer's disease.
Q52643231Tacrine(10)-hupyridone, a dual-binding acetylcholinesterase inhibitor, potently attenuates scopolamine-induced impairments of cognition in mice.
Q50859830The bivalent ligand approach as a tool for improving the in vitro anti-Alzheimer multitarget profile of dimebon.

Search more.