Tumoricidal effects of activated macrophages in a mouse model of chronic lymphocytic leukemia

scientific article published on June 2009

Tumoricidal effects of activated macrophages in a mouse model of chronic lymphocytic leukemia is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.4049/JIMMUNOL.0801847
P932PMC publication ID2712940
P698PubMed publication ID19454672
P5875ResearchGate publication ID24439337

P2093author name stringErik A Ranheim
Paul M Sondel
Qing-Li Wu
Alexander L Rakhmilevich
Ilia N Buhtoiarov
P2860cites workCutting edge: role of Toll-like receptor 1 in mediating immune response to microbial lipoproteinsQ24300005
Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathwayQ28216760
The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptorsQ28512624
CD40-ligand (CD154) gene therapy for chronic lymphocytic leukemiaQ33334835
Latent sensitivity to Fas-mediated apoptosis after CD40 ligation may explain activity of CD154 gene therapy in chronic lymphocytic leukemiaQ34020828
Human chronic lymphocytic leukemia modeled in mouse by targeted TCL1 expressionQ34068006
Activated T cells induce expression of B7/BB1 on normal or leukemic B cells through a CD40-dependent signalQ36361532
Infectious complications of chronic lymphocytic leukemiaQ36449680
Gene transfer of CD40-ligand induces autologous immune recognition of chronic lymphocytic leukemia B cellsQ37378914
Immunoregulatory cell dysfunction in chronic B-cell leukemiasQ37997489
Endosomal translocation of CpG-oligodeoxynucleotides inhibits DNA-PKcs-dependent IL-10 production in macrophagesQ38294773
TLR-9 activation of marginal zone B cells in lupus mice regulates immunity through increased IL-10 production.Q38329839
IL-12p70-dependent Th1 induction by human B cells requires combined activation with CD40 ligand and CpG DNA.Q38346264
Fas ligation induces apoptosis of CD40-activated human B lymphocytesQ39018355
L-NAME inhibits tumor cell progression and pulmonary metastasis of r/m HM-SFME-1 cells by decreasing NO from tumor cells and TNF-alpha from macrophagesQ40005831
Synergistic activation of macrophages via CD40 and TLR9 results in T cell independent antitumor effectsQ40338312
Preclinical antilymphoma activity of a humanized anti-CD40 monoclonal antibody, SGN-40.Q40372837
CD40 ligation activates murine macrophages via an IFN-gamma-dependent mechanism resulting in tumor cell destruction in vitroQ40425600
Intratumor CpG-Oligodeoxynucleotide Injection Induces Protective Antitumor T Cell ImmunityQ40628602
Role of nitric oxide in tumour progression: lessons from human tumoursQ41051336
CD40 activation does not protect chronic lymphocytic leukemia B cells from apoptosis induced by cytotoxic T lymphocytesQ41740503
CD154 induces p73 to overcome the resistance to apoptosis of chronic lymphocytic leukemia cells lacking functional p53.Q41953887
Innate defence functions of macrophages can be biased by nano-sized ceramic and metallic particles.Q42472435
Nitric oxide-dependent downregulation of adipocyte UCP-2 expression by tumor necrosis factor-alphaQ42795889
Transforming growth factor beta as endogenous growth inhibitor of chronic lymphocytic leukemia B cellsQ42942217
Suppression of pro-inflammatory cytokine release by selective inhibition of inducible nitric oxide synthase in mucosal explants from patients with ulcerative colitisQ44392036
Toll-like receptors stimulate human neutrophil functionQ44493366
Inducible nitric oxide synthase inhibitors prolonged the survival of skin xenografts through selective down-regulation of pro-inflammatory cytokine and CC-chemokine expressions.Q44612917
Expression of CD27 and its ligand, CD70, on chronic lymphocytic leukemia B cells.Q46065498
Anti-CD40 monoclonal antibody therapy in combination with irradiation results in a CD8 T-cell-dependent immunity to B-cell lymphomaQ48986235
Monoclonal antibody therapy of B cell lymphoma: signaling activity on tumor cells appears more important than recruitment of effectors.Q49094344
T cell progenitors emerge earlier than B cell progenitors in the murine fetal liver.Q51081086
Influence of adjuvant hormone therapy and chemotherapy on the immune system analysed in the bone marrow of patients with breast cancer.Q52008378
T cell immunity to lymphoma following treatment with anti-CD40 monoclonal antibodyQ56904563
Abnormal T-cell subpopulation function in CLL: excessive suppressor (T gamma) and deficient helper (T mu) activity with respect to B-cell proliferationQ70538883
Impaired natural killer activity in patients with chronic lymphocytic leukemia is associated with a deficiency of azurophilic cytoplasmic granules in putative NK cellsQ71000366
Immunostimulatory CpG-oligonucleotides cause proliferation, cytokine production, and an immunogenic phenotype in chronic lymphocytic leukemia B cellsQ73386737
Strategies for phenotyping apoptotic peripheral human lymphocytes comparing ISNT, annexin-V and 7-AAD cytofluorometric staining methodsQ74166415
CD40 antibody evokes a cytotoxic T-cell response that eradicates lymphoma and bypasses T-cell helpQ77402954
Conversion of tumor-specific CD4+ T-cell tolerance to T-cell priming through in vivo ligation of CD40Q77966184
Protective role of carnitine in breast cancer via decreasing arginase activity and increasing nitric oxideQ80773411
Tumoristatic effects of anti-CD40 mAb-activated macrophages involve nitric oxide and tumour necrosis factor-alphaQ83984890
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectlymphocyteQ715347
macrophageQ184204
leukemiaQ29496
chronic lymphocytic leukemiaQ1088156
P304page(s)6771-6778
P577publication date2009-06-01
P1433published inJournal of ImmunologyQ3521441
P1476titleTumoricidal effects of activated macrophages in a mouse model of chronic lymphocytic leukemia
P478volume182

Reverse relations

cites work (P2860)
Q39637537Anti-tumour synergy of cytotoxic chemotherapy and anti-CD40 plus CpG-ODN immunotherapy through repolarization of tumour-associated macrophages
Q26863784Functional Relationship between Tumor-Associated Macrophages and Macrophage Colony-Stimulating Factor as Contributors to Cancer Progression
Q36825411Immunomodulatory effects of interferons in malignancies
Q47153253Investigation of factors affecting the efficacy of 3C23K, a human monoclonal antibody targeting MISIIR.
Q34329242Macrophages in multiple myeloma: emerging concepts and therapeutic implications
Q34822571Microglia/macrophages promote glioma progression
Q36010202RhoH is critical for cell-microenvironment interactions in chronic lymphocytic leukemia in mice and humans
Q26773053TCL1 transgenic mouse model as a tool for the study of therapeutic targets and microenvironment in human B-cell chronic lymphocytic leukemia
Q43428464Th1 cytokines are more effective than Th2 cytokines at licensing anti-tumour functions in CD40-activated human macrophages in vitro
Q28751751The novel deacetylase inhibitor AR-42 demonstrates pre-clinical activity in B-cell malignancies in vitro and in vivo
Q36610868Tumor-associated myeloid cells can be activated in vitro and in vivo to mediate antitumor effects
Q35925252Tumoricidal Effects of Macrophage-Activating Immunotherapy in a Murine Model of Relapsed/Refractory Multiple Myeloma
Q90749110iNOS Interacts with Autophagy Receptor p62 and is Degraded by Autophagy in Macrophages

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