E2F1-induced upregulation of long noncoding RNA LINC00668 predicts a poor prognosis of gastric cancer and promotes cell proliferation through epigenetically silencing of CKIs

scientific article published on 23 December 2015

E2F1-induced upregulation of long noncoding RNA LINC00668 predicts a poor prognosis of gastric cancer and promotes cell proliferation through epigenetically silencing of CKIs is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.18632/ONCOTARGET.6745
P932PMC publication ID5029621
P698PubMed publication ID27036039

P2093author name stringZhi Xu
Dandan Yin
Wenming Chen
Liang Han
Jinfei Chen
Renhua Guo
Dongying Gu
Wei De
Rui Xia
Tongpeng Xu
Xuezhi He
Xinxin Si
Erbao Zhang
P2860cites workFinishing the euchromatic sequence of the human genomeQ22122488
A noncoding RNA is a potential marker of cell fate during mammary gland developmentQ24541606
Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasisQ24607308
A long noncoding RNA controls muscle differentiation by functioning as a competing endogenous RNAQ24630341
Long non-coding RNA ANRIL is required for the PRC2 recruitment to and silencing of p15(INK4B) tumor suppressor geneQ24632383
A coding-independent function of gene and pseudogene mRNAs regulates tumour biologyQ24632651
Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expressionQ24654249
Long noncoding RNAs in mouse embryonic stem cell pluripotency and differentiationQ24655701
Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAsQ24673619
Role of histone H3 lysine 27 methylation in Polycomb-group silencingQ28131795
SUZ12 is required for both the histone methyltransferase activity and the silencing function of the EED-EZH2 complexQ28269256
Cdks, cyclins and CKIs: roles beyond cell cycle regulationQ28294632
The Polycomb complex PRC2 and its mark in lifeQ29547358
Sibling rivalry in the E2F familyQ29615056
CDKN1C (p57) is a direct target of EZH2 and suppressed by multiple epigenetic mechanisms in breast cancer cellsQ33425892
Lnc RNA HOTAIR functions as a competing endogenous RNA to regulate HER2 expression by sponging miR-331-3p in gastric cancerQ33613022
Long noncoding RNA ANRIL indicates a poor prognosis of gastric cancer and promotes tumor growth by epigenetically silencing of miR-99a/miR-449aQ33688606
P53-regulated long non-coding RNA TUG1 affects cell proliferation in human non-small cell lung cancer, partly through epigenetically regulating HOXB7 expressionQ33720351
Signatures of polycomb repression and reduced H3K4 trimethylation are associated with p15INK4b DNA methylation in AML.Q33805966
Noncoding RNA in developmentQ34014009
A functional genomic approach identifies FAL1 as an oncogenic long noncoding RNA that associates with BMI1 and represses p21 expression in cancerQ34041980
The noncoding RNA MALAT1 is a critical regulator of the metastasis phenotype of lung cancer cellsQ34317898
Functional characterization of the TERRA transcriptome at damaged telomeres.Q34687678
EZH2-dependent suppression of a cellular senescence phenotype in melanoma cells by inhibition of p21/CDKN1A expressionQ34803805
The RB and p53 pathways in cancerQ34804764
Computational prediction of associations between long non-coding RNAs and proteinsQ34996482
Transcriptome sequencing across a prostate cancer cohort identifies PCAT-1, an unannotated lincRNA implicated in disease progressionQ35154249
Histone deacetylase HDAC4 promotes gastric cancer SGC-7901 cells progression via p21 repression.Q35181361
EZH2-mediated epigenetic suppression of long noncoding RNA SPRY4-IT1 promotes NSCLC cell proliferation and metastasis by affecting the epithelial-mesenchymal transitionQ36179615
The p53-induced lincRNA-p21 derails somatic cell reprogramming by sustaining H3K9me3 and CpG methylation at pluripotency gene promotersQ36293410
Long non-coding RNA ANRIL (CDKN2B-AS) is induced by the ATM-E2F1 signaling pathwayQ36910674
Polycomb protein Ezh2 regulates pancreatic beta-cell Ink4a/Arf expression and regeneration in diabetes mellitus.Q37175962
Long non-coding RNAs and chromatin modifiers: their place in the epigenetic codeQ37591534
Epidemiology of gastrointestinal and liver tumors.Q37760164
No-nonsense functions for long noncoding RNAsQ37865710
Cis-acting noncoding RNAs: friends and foesQ38058250
Cell cycle regulation by long non-coding RNAsQ38123666
Polycomb protein EZH2 regulates E2F1-dependent apoptosis through epigenetically modulating Bim expressionQ38349096
Long noncoding RNA GAPLINC regulates CD44-dependent cell invasiveness and associates with poor prognosis of gastric cancerQ38951043
Long noncoding RNA associated with microvascular invasion in hepatocellular carcinoma promotes angiogenesis and serves as a predictor for hepatocellular carcinoma patients' poor recurrence-free survival after hepatectomyQ39329786
MiR-196a is upregulated in gastric cancer and promotes cell proliferation by downregulating p27(kip1).Q39394939
Up-regulation of activation-induced cytidine deaminase causes genetic aberrations at the CDKN2b-CDKN2a in gastric cancerQ39679248
Centromere protein H is a novel prognostic marker for human nonsmall cell lung cancer progression and overall patient survivalQ39890752
microRNA-29 can regulate expression of the long non-coding RNA gene MEG3 in hepatocellular cancerQ41830068
The polycomb group gene product Ezh2 regulates proliferation and differentiation of murine hepatic stem/progenitor cells.Q43098140
LncRNA expression profile reveals the potential role of lncRNAs in gastric carcinogenesis.Q53222426
The STAT3-Binding Long Noncoding RNA lnc-DC Controls Human Dendritic Cell DifferentiationQ61645724
Expression of the E2F family in human gastrointestinal carcinomasQ77392025
Aberrant methylation in promoter regions of cyclin-dependent kinase inhibitor genes in adenoid cystic carcinoma of the salivary glandQ80645919
P433issue17
P407language of work or nameEnglishQ1860
P304page(s)23212-23226
P577publication date2015-12-23
P1433published inOncotargetQ1573155
P1476titleE2F1-induced upregulation of long noncoding RNA LINC00668 predicts a poor prognosis of gastric cancer and promotes cell proliferation through epigenetically silencing of CKIs
P478volume7

Reverse relations

cites work (P2860)
Q920740427-lncRNA Assessment Model for Monitoring and Prognosis of Breast Cancer Patients: Based on Cox Regression and Co-expression Analysis
Q38830087A novel lncRNA, GASL1, inhibits cell proliferation and restricts E2F1 activity.
Q94215728A novel long non-coding RNA NFIA-AS1 is down-regulated in gastric cancer and inhibits proliferation of gastric cancer cells
Q58709660CDCA3 mediates p21-dependent proliferation by regulating E2F1 expression in colorectal cancer
Q90705910Cancer-related long noncoding RNAs show aberrant expression profiles and competing endogenous RNA potential in esophageal adenocarcinoma
Q37699208Comprehensive analysis of aberrantly expressed profiles of lncRNAs and miRNAs with associated ceRNA network in muscle-invasive bladder cancer
Q37497564Differential transcription profiles of long non-coding RNAs in primary human brain microvascular endothelial cells in response to meningitic Escherichia coli
Q41242612Differentially Expressed lncRNAs in Gastric Cancer Patients: A Potential Biomarker for Gastric Cancer Prognosis
Q55255678Epigenetic regulation of long non-coding RNAs in gastric cancer.
Q36313998From big data to diagnosis and prognosis: gene expression signatures in liver hepatocellular carcinoma
Q52721971Genetic and Epigenetic Control of CDKN1C Expression: Importance in Cell Commitment and Differentiation, Tissue Homeostasis and Human Diseases.
Q92738235Genome‑wide investigation of the clinical implications and molecular mechanism of long noncoding RNA LINC00668 and protein‑coding genes in hepatocellular carcinoma
Q37696211Helicobacter pylori infection related long noncoding RNA (lncRNA) AF147447 inhibits gastric cancer proliferation and invasion by targeting MUC2 and up-regulating miR-34c
Q89967048Linc00668 Promotes Invasion and Stem Cell-Like Properties of Breast Cancer Cells by Interaction With SND1
Q92354568LncRNA LINC00668 promotes the progression of breast cancer by inhibiting apoptosis and accelerating cell cycle
Q47601811Long Non Coding RNA Expression Intersecting Cancer and Spermatogenesis: A Systematic Review
Q49678630Long non-coding RNA Lucat1 is a poor prognostic factor and demonstrates malignant biological behavior in clear cell renal cell carcinoma.
Q91608059Long non-coding RNA MIF-AS1 promotes gastric cancer cell proliferation and reduces apoptosis to upregulate NDUFA4
Q47950205Long non-coding RNA SNHG17 is an unfavourable prognostic factor and promotes cell proliferation by epigenetically silencing P57 in colorectal cancer
Q28072366Long non-coding RNAs in anti-cancer drug resistance
Q28078143Long non-coding RNAs in the regulation of myeloid cells
Q90482033Long noncoding RNA, LINC00460, as a prognostic biomarker in head and neck squamous cell carcinoma (HNSCC)
Q97518944Long noncoding RNAs in gastric cancer: From molecular dissection to clinical application
Q49568166MicroRNA-122-3p inhibits tumor cell proliferation and induces apoptosis by targeting Forkhead box O in A549 cells.
Q91689722Ophiopogonin-B Suppresses Epithelial-mesenchymal Transition in Human Lung Adenocarcinoma Cells via the Linc00668/miR-432-5p/EMT Axis
Q58781877Prognostic value of long noncoding RNAs in gastric cancer: a meta-analysis
Q64055609Sodium new houttuyfonate suppresses metastasis in NSCLC cells through the Linc00668/miR-147a/slug axis
Q93383012Targeting LINC00673 expression triggers cellular senescence in lung cancer
Q42056934The novel long non-coding RNA TALNEC2, regulates tumor cell growth and the stemness and radiation response of glioma stem cells
Q47131652Transcription factor E2F1 promotes EMT by regulating ZEB2 in small cell lung cancer
Q49536537Upregulation of LncRNA BCYRN1 promotes tumor progression and enhances EpCAM expression in gastric carcinoma.

Search more.