Epigallocatechin-3-gallate prevents oxidative stress-induced cellular senescence in human mesenchymal stem cells via Nrf2

scientific article published on August 2016

Epigallocatechin-3-gallate prevents oxidative stress-induced cellular senescence in human mesenchymal stem cells via Nrf2 is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.3892/IJMM.2016.2694
P932PMC publication ID5029951
P698PubMed publication ID27498709

P50authorJoo-Hyun ShinQ88299532
P2093author name stringJihye Park
Mi-Sook Chang
Hyo-Jin Jeon
P2860cites workNegative control of p53 by Sir2alpha promotes cell survival under stressQ24291828
hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylaseQ24291829
Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescenceQ24297146
The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinasesQ24319848
Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domainQ24609907
The Nrf2-antioxidant response element signaling pathway and its activation by oxidative stressQ24648021
Multilineage potential of adult human mesenchymal stem cellsQ27860737
WAF1, a potential mediator of p53 tumor suppressionQ27861121
The hallmarks of agingQ28131641
Cellular senescence: when bad things happen to good cellsQ29615561
Phase I pharmacokinetic study of tea polyphenols following single-dose administration of epigallocatechin gallate and polyphenon E.Q32014801
Stem cell aging: mechanisms, regulators and therapeutic opportunitiesQ34159765
The essence of senescenceQ34288983
Tea catechins and polyphenols: health effects, metabolism, and antioxidant functionsQ35066981
Redox-sensitive transcription factors as prime targets for chemoprevention with anti-inflammatory and antioxidative phytochemicalsQ36326604
Preventive effects of epigallocatechin-3-O-gallate against replicative senescence associated with p53 acetylation in human dermal fibroblastsQ36424772
Acetylation of p53 augments its site-specific DNA binding both in vitro and in vivoQ36601373
Inhibition of nuclear factor-erythroid 2-related factor (Nrf2) by caveolin-1 promotes stress-induced premature senescenceQ36926609
Sublethal oxidative stress induces the premature senescence of human mesenchymal stem cells derived from endometriumQ37156197
NRF2 and KEAP1 mutations: permanent activation of an adaptive response in cancerQ37423465
Moving from the laboratory bench to patients' bedside: considerations for effective therapy with stem cells.Q37949680
Transcription factor Nrf2 maintains the basal expression of Mdm2: An implication of the regulation of p53 signaling by Nrf2.Q39611422
Evidence that transcriptional activation by p53 plays a direct role in the induction of cellular senescence.Q41150575
Bypass of senescence after disruption of p21CIP1/WAF1 gene in normal diploid human fibroblastsQ42815554
Green tea catechins partially protect DNA from (.)OH radical-induced strand breaks and base damage through fast chemical repair of DNA radicalsQ43686239
Keap1, the sensor for electrophiles and oxidants that regulates the phase 2 response, is a zinc metalloprotein.Q46467626
Polyphenols suppress hydrogen peroxide-induced oxidative stress in human bone-marrow derived mesenchymal stem cellsQ48571010
Oxidative stress induces senescence in human mesenchymal stem cells.Q54384642
Real-time imaging of transcriptional activation in live cells reveals rapid up-regulation of the cyclin-dependent kinase inhibitor gene CDKN1A in replicative cellular senescenceQ79369075
Silent information regulator 2 (SIRT1) attenuates oxidative stress-induced mesangial cell apoptosis via p53 deacetylationQ79753759
P4510describes a project that usesImageJQ1659584
P433issue4
P921main subjectcellular senescenceQ9075999
P304page(s)1075-1082
P577publication date2016-08-01
P1433published inInternational Journal of Molecular MedicineQ6051492
P1476titleEpigallocatechin-3-gallate prevents oxidative stress-induced cellular senescence in human mesenchymal stem cells via Nrf2
P478volume38

Reverse relations

cites work (P2860)
Q39402253Antioxidants Mediate Both Iron Homeostasis and Oxidative Stress
Q47640793Caveolin‑1 regulates oxidative stress‑induced senescence in nucleus pulposus cells primarily via the p53/p21 signaling pathway in vitro
Q60952216Combination of Epigallocatechin Gallate and Sulforaphane Counteracts In Vitro Oxidative Stress and Delays Stemness Loss of Amniotic Fluid Stem Cells
Q52331716Inducers of Senescence, Toxic Compounds, and Senolytics: The Multiple Faces of Nrf2-Activating Phytochemicals in Cancer Adjuvant Therapy.
Q94672685Looking for immortality: Review of phytotherapy for stem cell senescence
Q64764624N-acetyl-cysteine blunts 6-hydroxydopamine- and L-buthionine-sulfoximine-induced apoptosis in human mesenchymal stromal cells
Q59133558Nectar Supplementation Reduced Biomarkers of Oxidative Stress, Muscle Damage, and Improved Psychological Response in Highly Trained Young Handball Players
Q92921747Preclinical Pharmacological Activities of Epigallocatechin-3-gallate in Signaling Pathways: An Update on Cancer
Q47982699Protective effects of a green tea polyphenol, epigallocatechin-3-gallate, against sevoflurane-induced neuronal apoptosis involve regulation of CREB/BDNF/TrkB and PI3K/Akt/mTOR signalling pathways in neonatal mice

Search more.