Expression of 5-lipoxygenase and 15-lipoxygenase in rheumatoid arthritis synovium and effects of intraarticular glucocorticoids

scientific article published on 04 June 2009

Expression of 5-lipoxygenase and 15-lipoxygenase in rheumatoid arthritis synovium and effects of intraarticular glucocorticoids is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1024671825
P356DOI10.1186/AR2717
P932PMC publication ID2714134
P698PubMed publication ID19497113
P5875ResearchGate publication ID26267357

P50authorHans-Erik ClaessonQ57050325
Olof RådmarkQ64750530
P2093author name stringKarina Roxana Gheorghe
Per-Johan Jakobsson
Marina Korotkova
Anca Irinel Catrina
Linda Backman
Erik af Klint
P2860cites workInteraction of human 15-lipoxygenase-1 with phosphatidylinositol bisphosphates results in increased enzyme activityQ24307726
Specific inflammatory cytokines regulate the expression of human monocyte 15-lipoxygenaseQ24563459
Eoxins are proinflammatory arachidonic acid metabolites produced via the 15-lipoxygenase-1 pathway in human eosinophils and mast cellsQ24648965
Intraarticular corticosteroids decrease synovial RANKL expression in inflammatory arthritisQ57349771
Synovitis reduced by inhibition of leukotriene B4: Carragheenan-induced gonarthritis studied in dogsQ61711836
Zileuton, a 5-lipoxygenase inhibitor in rheumatoid arthritisQ67867727
Leukotriene B4 as a mediator of early and late reactions to antigen in humans: the effect of systemic glucocorticoid treatment in vivoQ69057699
15-Hydroxy-eicosatetraenoic acid (15-HETE) inhibits carrageenan-induced experimental arthritis and reduces synovial fluid leukotriene B4 (LTB4)Q69350027
Anti-inflammatory drugs in experimental atherosclerosis. 7. Spontaneous atherosclerosis in WHHL rabbits and inhibition by cortisone acetateQ69350339
Interleukin 13 suppresses cytokine production and stimulates the production of 15-HETE in PBMC. A comparison between IL-4 and IL-13Q70971532
The presence of interleukin-13 in rheumatoid synovium and its antiinflammatory effects on synovial fluid macrophages from patients with rheumatoid arthritisQ71620541
Leukotriene B4 stimulates osteoclastic bone resorption both in vitro and in vivoQ71773557
Dexamethasone inhibits the production of thromboxane B2 and leukotriene B4 by human alveolar and peritoneal macrophages in cultureQ72396938
Increased serum leukotriene B4 level in the active stage of rheumatoid arthritis in childrenQ73195415
15-Lipoxygenase expression and 15(S)-hydroxyeicoisatetraenoic acid release and reincorporation in induced sputum of asthmatic subjectsQ73651109
Arachidonate 15-lipoxygenase of reticulocyte-type in human rheumatoid arthritis type B synoviocytes and modulation of its activity by proinflammatory cytokinesQ77762605
Inhibited aortic aneurysm formation in BLT1-deficient miceQ80500137
Inhibition by methylprednisolone of zymosan-induced leukotriene synthesis in alveolar macrophagesQ93536217
B lymphocyte autoimmunity in rheumatoid synovitis is independent of ectopic lymphoid neogenesisQ94702098
Functional classes of bronchial mucosa genes that are differentially expressed in asthmaQ24795231
The american rheumatism association 1987 revised criteria for the classification of rheumatoid arthritisQ27860872
Lipoxins and aspirin-triggered 15-epi-lipoxins are the first lipid mediators of endogenous anti-inflammation and resolutionQ28183175
New endogenous anti-inflammatory and proresolving lipid mediators: implications for rheumatic diseasesQ28222356
Induction of 15-lipoxygenase by interleukin-13 in human blood monocytesQ28240849
5-Lipoxygenase metabolites inhibit bone formation in vitroQ28275044
Relationship between leukotriene B4 and immunological parameters in rheumatoid synovial fluidsQ28321995
Lipoxygenation of arachidonic acid as a source of polymorphonuclear leukocyte chemotactic factors in synovial fluid and tissue in rheumatoid arthritis and spondyloarthritisQ28366047
12/15-lipoxygenase regulates intercellular adhesion molecule-1 expression and monocyte adhesion to endothelium through activation of RhoA and nuclear factor-kappaB.Q30438056
High expression of 5-lipoxygenase in normal and malignant mantle zone B lymphocytesQ33398788
Leukotriene B4, a mediator of inflammation present in synovial fluid in rheumatoid arthritisQ33554843
Detection of cytokine producing cells in the synovial membrane from patients with rheumatoid arthritisQ33578241
Inhibition of eicosanoid biosynthesis by glucocorticoids in humansQ33783999
Human alveolar macrophages have 15-lipoxygenase and generate 15(S)-hydroxy-5,8,11-cis-13-trans-eicosatetraenoic acid and lipoxinsQ33903345
Caspase-mediated degradation of human 5-lipoxygenase in B lymphocytic cellsQ33948003
Reduced inflammation and tissue damage in transgenic rabbits overexpressing 15-lipoxygenase and endogenous anti-inflammatory lipid mediatorsQ34282093
The role of leukotrienes in inflammationQ34324567
Corticosteroids: the drugs to beatQ34488032
The two faces of the 15-lipoxygenase in atherosclerosisQ34687589
IL-4 determines eicosanoid formation in dendritic cells by down-regulation of 5-lipoxygenase and up-regulation of 15-lipoxygenase 1 expressionQ35866426
Neutrophil-derived leukotriene B4 is required for inflammatory arthritisQ36228578
Inflammation and immune regulation by 12/15-lipoxygenasesQ36469920
Leukotrienes and other products of the 5-lipoxygenase pathway. Biochemistry and relation to pathobiology in human diseasesQ37888849
Effects of oral prednisolone on biomarkers in synovial tissue and clinical improvement in rheumatoid arthritisQ39702734
Regulation of monocyte chemoattractant protein-1 by the oxidized lipid, 13-hydroperoxyoctadecadienoic acid, in vascular smooth muscle cells via nuclear factor-kappa B (NF-kappa B).Q40567462
5-Lipoxygenase upregulation by dexamethasone in human mast cellsQ40911812
The neutrophil in rheumatoid arthritis.Q40976141
Dexamethasone Increases Expression of 5‐Lipoxygenase and its Activating Protein in Human Monocytes and THP‐1 CellsQ41110058
Stimulation of matrix metalloproteinase‐dependent migration of T cells by eicosanoidsQ41277804
Human B lymphocytes possess 5-lipoxygenase activity and convert arachidonic acid to leukotriene B4.Q41674889
Interleukin 4 induces transcription of the 15-lipoxygenase I gene in human endothelial cellsQ43607825
Antiinflammatory mediator lipoxin A4 and its receptor in synovitis of patients with rheumatoid arthritisQ44391513
Cooperative induction of 15-lipoxygenase in rheumatoid synovial cells by IL-4 and proinflammatory cytokines.Q44740046
Expression of microsomal prostaglandin E synthase 1 in rheumatoid arthritis synoviumQ44930014
Reticulocyte 15-lipoxygenase-I is important in acetylcholine-induced endothelium-dependent vasorelaxation in rabbit aortaQ46766143
Prednisolone in early rheumatoid arthritis: an antiinvasive effectQ46778824
Intraarticular glucocorticoid treatment reduces inflammation in synovial cell infiltrations more efficiently than in synovial blood vesselsQ46829587
Expression of 15-lipoxygenase type-1 in human mast cellsQ50335981
Enhancement of leukotriene A4 biosynthesis in neutrophils from patients with rheumatoid arthritis after a single glucocorticoid dose.Q54015381
P433issue3
P921main subjectrheumatoid arthritisQ187255
P304page(s)R83
P577publication date2009-06-04
P1433published inArthritis Research and TherapyQ15757229
P1476titleExpression of 5-lipoxygenase and 15-lipoxygenase in rheumatoid arthritis synovium and effects of intraarticular glucocorticoids
P478volume11

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cites work (P2860)
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