Cholera toxin inhibits IL-12 production and CD8alpha+ dendritic cell differentiation by cAMP-mediated inhibition of IRF8 function. (scientific article published on June 2009)

In vivo microbial stimulation induces rapid CD40 ligand-independent production of interleukin 12 by dendritic cells and their redistribution to T cell areas

Q24652833

ICSBP is essential for the development of mouse type I interferon-producing cells and for the generation and activation of CD8alpha(+) dendritic cells

Q24672345

Synergistic activation of interleukin-12 p35 gene transcription by interferon regulatory factor-1 and interferon consensus sequence-binding protein

Q28288262

Essential role for ICSBP in the in vivo development of murine CD8alpha + dendritic cells

Q28505356

Interferon consensus sequence binding protein-deficient mice display impaired resistance to intracellular infection due to a primary defect in interleukin 12 p40 induction

Q28513103

Oral administration of recombinant cholera toxin subunit B inhibits IL-12-mediated murine experimental (trinitrobenzene sulfonic acid) colitis

Q32024894

Oral immunization with Toxoplasma gondii antigens in association with cholera toxin induces enhanced protective and cell-mediated immunity in C57BL/6 mice.

Q33597025

Partner-regulated interaction of IFN regulatory factor 8 with chromatin visualized in live macrophages.

Q34063504

Regulation of interleukin-12 production by G-protein-coupled receptors

Q34184407

Intranasal immunization with SAG1 protein of Toxoplasma gondii in association with cholera toxin dramatically reduces development of cerebral cysts after oral infection

Q35498094

Effects of cholera toxin on innate and adaptive immunity and its application as an immunomodulatory agent

Q35619878

Inhibiting cytokines of the interleukin-12 family: recent advances and novel challenges.

Q35684429

Cholera toxin discriminates between T helper 1 and 2 cells in T cell receptor-mediated activation: role of cAMP in T cell proliferation

Q36352052

Cholera toxin suppresses interleukin (IL)-12 production and IL-12 receptor beta1 and beta2 chain expression

Q36367736

Cytokine regulation of immunopathology in toxoplasmosis

Q36709991

IFN-gamma-induced TNF-alpha expression is regulated by interferon regulatory factors 1 and 8 in mouse macrophages

Q39938350

IRF-8/ICSBP and IRF-1 cooperatively stimulate mouse IL-12 promoter activity in macrophages

Q40692173

An IFN-gamma-inducible transcription factor, IFN consensus sequence binding protein (ICSBP), stimulates IL-12 p40 expression in macrophages

Q40872805

Regulation of IFN consensus sequence binding protein expression in murine macrophages

Q40950508

Bordetella pertussis inhibition of interleukin-12 (IL-12) p70 in human monocyte-derived dendritic cells blocks IL-12 p35 through adenylate cyclase toxin-dependent cyclic AMP induction

Q42047758

Adenylate cycalse toxin of Bordetella pertussis inhibits TLR-induced IRF-1 and IRF-8 activation and IL-12 production and enhances IL-10 through MAPK activation in dendritic cells

Q46653871

Simultaneous depletion of CD4+ and CD8+ T lymphocytes is required to reactivate chronic infection with Toxoplasma gondii

Q48464908

ICSBP directs bipotential myeloid progenitor cells to differentiate into mature macrophages.

Q53437189

ICSBP/IRF-8 retrovirus transduction rescues dendritic cell development in vitro

Q56880723

Rapid recruitment of neutrophils containing prestored IL-12 during microbial infection

Q73086237

Phosphorylation events modulate the ability of interferon consensus sequence binding protein to interact with interferon regulatory factors and to bind DNA

Q73201778

Activation of the murine interleukin-12 p40 promoter by functional interactions between NFAT and ICSBP

Q73699662

A murine model of IgE-mediated cow's milk hypersensitivity

Q78016130

Identification of IFN regulatory factor-1 binding site in IL-12 p40 gene promoter

Q78762621

Cutting edge: IFN consensus sequence binding protein/IFN regulatory factor 8 drives the development of type I IFN-producing plasmacytoid dendritic cells

Q78826826

P433

issue

P407

language of work or name

English

Q1860

P921

main subject

cholera

cell differentiation

dendritic cell

page(s)

1227-1235

P577

publication date

2009-06-01

P1433

published in

Journal of Experimental Medicine

Q3186912

P1476

title

Cholera toxin inhibits IL-12 production and CD8alpha+ dendritic cell differentiation by cAMP-mediated inhibition of IRF8 function

P478

volume

206

Reverse relations

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