IGF-1R contributes to stress-induced hepatocellular damage in experimental cholestasis

scientific article published on 23 July 2009

IGF-1R contributes to stress-induced hepatocellular damage in experimental cholestasis is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.2353/AJPATH.2009.081081
P932PMC publication ID2716962
P698PubMed publication ID19628767
P5875ResearchGate publication ID26692052

P50authorColette ReyQ127464857
François TroncheQ130272213
P2093author name stringMartin Holzenberger
Chantal Housset
Dominique Wendum
Axelle Cadoret
Khaldoun Elriz
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A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axisQ28280037
Insulin-like growth factor 1 and oestradiol promote cell proliferation of MCF-7 breast cancer cells: new insights into their synergistic effectsQ28365959
Regulated translation initiation controls stress-induced gene expression in mammalian cellsQ28506388
Targeted disruption of the Chop gene delays endoplasmic reticulum stress-mediated diabetesQ28506402
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Crosstalk between steroid receptors and the c-Src-receptor tyrosine kinase pathways: implications for cell proliferationQ30434843
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Hepatocyte proliferation during liver regeneration is impaired in mice with liver-specific IGF-1R knockoutQ82581005
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Bile acids up-regulate death receptor 5/TRAIL-receptor 2 expression via a c-Jun N-terminal kinase-dependent pathway involving Sp1.Q38349203
Insulin-like growth factor-I protects cells from ER stress-induced apoptosis via enhancement of the adaptive capacity of endoplasmic reticulum.Q39988254
Fibrosis correlates with a ductular reaction in hepatitis C: roles of impaired replication, progenitor cells and steatosisQ42991520
Hepatocyte-specific expression of Cre recombinaseQ43604415
Bile system morphogenesis defects and liver dysfunction upon targeted deletion of HNF1beta.Q43948844
Role of farnesoid X receptor in determining hepatic ABC transporter expression and liver injury in bile duct-ligated miceQ44569549
Protective effect of IGF-1 on experimental liver cirrhosis-induced common bile duct ligation.Q44706857
Determination of malonaldehyde precursor in tissues by thiobarbituric acid testQ44764466
Multidrug resistance-associated protein 4 is up-regulated in liver but down-regulated in kidney in obstructive cholestasis in the rat.Q44805394
Gefitinib, an EGFR inhibitor, prevents hepatocellular carcinoma development in the rat liver with cirrhosisQ45231150
Liver transduction with a simian virus 40 vector encoding insulin-like growth factor I reduces hepatic damage and the development of liver cirrhosisQ45411464
Low doses of insulin-like growth factor-I induce mitochondrial protection in aging ratsQ46752594
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Superoxide anions and hydrogen peroxide induce hepatocyte death by different mechanisms: involvement of JNK and ERK MAP kinasesQ46822908
CHOP deficiency attenuates cholestasis-induced liver fibrosis by reduction of hepatocyte injuryQ46823993
Fibroblasts from long-lived Snell dwarf mice are resistant to oxygen-induced in vitro growth arrestQ46915360
IGF-I induces DNA synthesis and apoptosis in rat liver hepatic stellate cells (HSC) but DNA synthesis and proliferation in rat liver myofibroblasts (rMF).Q47446541
Expression of the insulin-like growth factor I receptor C terminus as a myristylated protein leads to induction of apoptosis in tumor cells.Q48544609
Hepatocyte apoptosis after bile duct ligation in the mouse involves Fas.Q50517174
Alpha-1 antitrypsin Z protein (PiZ) increases hepatic fibrosis in a murine model of cholestasis.Q50684835
Adaptative bile duct proliferative response in experimental bile duct ischemia.Q50776604
Progressive fibrosis in nonalcoholic steatohepatitis: association with altered regeneration and a ductular reaction.Q53540807
Multiplex stress resistance in cells from long-lived dwarf mice.Q53925947
Expression of the bile salt export pump is maintained after chronic cholestasis in the rat.Q54067686
c-myc-induced hepatocarcinogenesis in the absence of IGF-I receptor.Q54688528
A targeted partial invalidation of the insulin-like growth factor I receptor gene in mice causes a postnatal growth deficitQ56901705
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Role of glutathione, lipid peroxidation and antioxidants on acute bile-duct obstruction in the ratQ73207429
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)627-635
P577publication date2009-07-23
P1433published inThe American Journal of PathologyQ4744259
P1476titleIGF-1R contributes to stress-induced hepatocellular damage in experimental cholestasis
P478volume175

Reverse relations

cites work (P2860)
Q42824021A protective role for CD154 in hepatic steatosis in mice
Q50546416Deleting IGF-1 receptor from forebrain neurons confers neuroprotection during stroke and upregulates endocrine somatotropin.
Q38114062Targeted therapies in the treatment of advanced hepatocellular carcinoma

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