Mechanisms underlying prorenin actions on hypothalamic neurons implicated in cardiometabolic control

scientific article published on 04 August 2016

Mechanisms underlying prorenin actions on hypothalamic neurons implicated in cardiometabolic control is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.MOLMET.2016.07.010
P932PMC publication ID5034613
P698PubMed publication ID27688999

P50authorYumei FengQ61731773
P2093author name stringJavier E Stern
Soledad Pitra
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(Pro)renin receptor mediates both angiotensin II-dependent and -independent oxidative stress in neuronal cellsQ34629536
Leptin activates oxytocin neurons of the hypothalamic paraventricular nucleus in both control and diet-induced obese rodentsQ34635349
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Subnuclei in the rat hypothalamic paraventricular nucleus: a cytoarchitectural, horseradish peroxidase and immunocytochemical analysisQ71374069
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Adipocyte (Pro)Renin-Receptor Deficiency Induces Lipodystrophy, Liver Steatosis and Increases Blood Pressure in Male MiceQ36989385
Intracerebroventricular infusion of the (Pro)renin receptor antagonist PRO20 attenuates deoxycorticosterone acetate-salt-induced hypertensionQ36992645
Hypothalamic inflammation: marker or mechanism of obesity pathogenesis?Q37031049
Enhanced NMDA receptor-mediated intracellular calcium signaling in magnocellular neurosecretory neurons in heart failure ratsQ37323514
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Dendritic peptide release mediates interpopulation crosstalk between neurosecretory and preautonomic networks.Q37448680
Neuron-specific (pro)renin receptor knockout prevents the development of salt-sensitive hypertensionQ37626138
Segregation of calcium signalling mechanisms in magnocellular neurones and terminals.Q37990198
Hormones and diet, but not body weight, control hypothalamic microglial activityQ38311585
Impact of the prorenin/renin receptor on the development of obesity and associated cardiometabolic risk factorsQ42205259
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Exposure to a high-fat diet alters leptin sensitivity and elevates renal sympathetic nerve activity and arterial pressure in rabbits.Q43145688
Nucleus of the solitary tract (pro)renin receptor-mediated antihypertensive effect involves nuclear factor-κB-cytokine signaling in the spontaneously hypertensive rat.Q43418066
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Activation of the systemic and adipose renin-angiotensin system in rats with diet-induced obesity and hypertensionQ44932414
Blockade of the renin-angiotensin system decreases adipocyte size with improvement in insulin sensitivityQ45054457
Transgenic expression of enhanced green fluorescent protein enables direct visualization for physiological studies of vasopressin neurons and isolated nerve terminals of the rat.Q45064074
Excitability of paraventricular nucleus neurones that project to the rostral ventrolateral medulla is regulated by small-conductance Ca2+-activated K+ channels.Q45937879
An osmosensitive voltage-gated K+ current in rat supraoptic neurons.Q45985994
Enhancement of calcium-dependent afterpotentials in oxytocin neurons of the rat supraoptic nucleus during lactationQ46477250
Reduced outward K+ conductances generate depolarizing after-potentials in rat supraoptic nucleus neuronesQ46542968
(Pro)renin receptor-mediated activation of mitogen-activated protein kinases in human vascular smooth muscle cellsQ46771469
Prorenin and renin-induced extracellular signal-regulated kinase 1/2 activation in monocytes is not blocked by aliskiren or the handle-region peptideQ46796595
Effect of central angiotensin II on body weight gain in young ratsQ47174575
Effect of intracerebroventricular angiotensin II on body weight and food intake in adult ratsQ47421077
Enhanced adipose afferent reflex contributes to sympathetic activation in diet-induced obesity hypertensionQ48126287
Components of after-hyperpolarization in magnocellular neurones of the rat supraoptic nucleus in vitro.Q48355543
Calcium-dependent potassium conductance in rat supraoptic nucleus neurosecretory neurons.Q48429416
Neural projections from paraventricular nucleus that subserve vasomotor functions.Q48515937
Electrophysiological and morphological properties of pre-autonomic neurones in the rat hypothalamic paraventricular nucleus.Q48710885
Angiotensin synthesis in the brain and increased turnover in hypertensive rats.Q48758370
Angiotensinogen levels and obesity in four black populations. ICSHIB Investigators.Q50658384
Adipose depot-specific modulation of angiotensinogen gene expression in diet-induced obesityQ58656685
M-currents and other potassium currents in bullfrog sympathetic neuronesQ67247604
Incidence and precursors of hypertension in young adults: the Framingham Offspring StudyQ69038435
Intracellular calcium directly inhibits potassium M channels in excised membrane patches from rat sympathetic neuronsQ70901383
P4510describes a project that usesImageJQ1659584
P433issue10
P304page(s)858-868
P577publication date2016-08-04
P1433published inMolecular MetabolismQ27724805
P1476titleMechanisms underlying prorenin actions on hypothalamic neurons implicated in cardiometabolic control
P478volume5

Reverse relations

cites work (P2860)
Q46348355A-type K+ channels contribute to the prorenin increase of firing activity in hypothalamic vasopressin neurosecretory neurons
Q92525882The (pro)renin receptor in health and disease
Q47443231The Prorenin Receptor in the Cardiovascular System and Beyond
Q58562702The renin-angiotensin system in cardiovascular autonomic control: recent developments and clinical implications

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