5-Lipoxygenase-mediated endogenous DNA damage.

scientific article published on 23 April 2009

5-Lipoxygenase-mediated endogenous DNA damage. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M109.011841
P8608Fatcat IDrelease_cj63qiqerbgn3gugjwsd23i3bi
P932PMC publication ID2719316
P698PubMed publication ID19390118

P50authorSeon Hwa LeeQ44225348
P2093author name stringIan A Blair
Michelle V Williams
Wenying Jian
P2860cites work5-lipoxygenase and 5-lipoxygenase-activating protein are localized in the nuclear envelope of activated human leukocytesQ24320095
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Evidence for 5-lipoxygenase activity in human B cell lines. A possible role for arachidonic acid metabolites during B cell signal transductionQ41739498
Vitamin C-induced decomposition of lipid hydroperoxides to endogenous genotoxinsQ43642026
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The 5-lipoxygenase pathway promotes pathogenesis of hyperlipidemia-dependent aortic aneurysm.Q45025551
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Relationship of arachidonic acid metabolizing enzyme expression in epithelial cancer cell lines to the growth effect of selective biochemical inhibitors.Q53423897
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Expression of 5-lipoxygenase (5-LOX) in T lymphocytes.Q53555004
MK886, a potent and specific leukotriene biosynthesis inhibitor blocks and reverses the membrane association of 5-lipoxygenase in ionophore-challenged leukocytesQ67267224
Bacterial expression, purification and partial characterization of recombinant rabbit reticulocyte 15-lipoxygenaseQ70742571
Stereochemistry of oxygenation of linoleic acid catalyzed by prostaglandin-endoperoxide H synthase-2Q74113814
15-Lipoxygenation of phospholipids may precede the sn-2 cleavage by phospholipases A2: reaction specificities of secretory and cytosolic phospholipases A2 towards native and 15-lipoxygenated arachidonoyl phospholipidsQ77318013
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5-Lipoxygenase and leukotriene B(4) receptor are expressed in human pancreatic cancers but not in pancreatic ducts in normal tissueQ24685466
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Cyclooxygenase-2-mediated DNA damageQ28181042
Targeted chiral lipidomics analysisQ28187185
Expanding expression of the 5-lipoxygenase pathway within the arterial wall during human atherogenesisQ28205296
Accumulation of 8-oxo-deoxyguanosine in cardiovascular tissues with the development of hypertensionQ28571663
Lipoxygenase-5 is overexpressed in prostate adenocarcinomaQ32159450
Protein adducts generated from products of lipid oxidation: focus on HNE and one.Q33265402
Targeted lipidomics using electron capture atmospheric pressure chemical ionization mass spectrometryQ33430358
Unexpected formation of etheno-2'-deoxyguanosine adducts from 5(S)-hydroperoxyeicosatetraenoic acid: evidence for a bis-hydroperoxide intermediateQ33433071
Targeted chiral lipidomics analysis by liquid chromatography electron capture atmospheric pressure chemical ionization mass spectrometry (LC-ECAPCI/MS).Q33438378
Lipoxygenase inhibitors as potential cancer chemopreventivesQ33647970
Elevated levels of oxidative DNA damage and DNA repair enzymes in human atherosclerotic plaquesQ34145177
Lipid hydroperoxide-mediated DNA damageQ34348782
Oxidative DNA damage and cardiovascular diseaseQ34423098
Micronutrients: dietary intake v. supplement use.Q34470904
The phospholipase A2 superfamily and its group numbering systemQ34566140
Cyclooxygenase-2-mediated metabolism of arachidonic acid to 15-oxo-eicosatetraenoic acid by rat intestinal epithelial cellsQ34696777
Leukotriene B4 receptor antagonists as therapeutics for inflammatory disease: preclinical and clinical developmentsQ34718549
Regulation of enzymatic lipid peroxidation: the interplay of peroxidizing and peroxide reducing enzymesQ34727520
Vitamin C antagonizes the cytotoxic effects of antineoplastic drugsQ34842453
Mammalian arachidonate 15-lipoxygenases structure, function, and biological implicationsQ34997971
Coronary atherosclerosis and somatic mutations: an overview of the contributive factors for oxidative DNA damage.Q35037752
Biological significance of phospholipid hydroperoxide glutathione peroxidase (PHGPx, GPx4) in mammalian cellsQ35042904
5-Lipoxygenase and atherosclerosisQ35539445
5-Lipoxygenase: Cellular Biology and Molecular PharmacologyQ35560651
Lipoxygenase pathways in atherogenesisQ35840304
Arachidonic acid signaling in pathogenesis of allergy: therapeutic implications.Q36107615
The role of leukotrienes in allergic rhinitisQ36177570
The 5-lipoxygenase pathway in arterial wall biology and atherosclerosisQ36218949
The role of leukotrienes in the pathophysiology of inflammatory disorders: is there a case for revisiting leukotrienes as therapeutic targets?Q36533935
Five-lipoxygenase pathway of arachidonic acid metabolism in carcino-genesis and cancer chemopreventionQ36651760
COX-2/5-LOX dual acting anti-inflammatory drugs in cancer chemotherapy.Q36737980
P433issue25
P407language of work or nameEnglishQ1860
P921main subjectDNA damageQ5205747
P304page(s)16799-16807
P577publication date2009-04-23
P1433published inJournal of Biological ChemistryQ867727
P1476title5-Lipoxygenase-mediated endogenous DNA damage
P478volume284

Reverse relations

cites work (P2860)
Q3498747115-oxo-Eicosatetraenoic acid, a metabolite of macrophage 15-hydroxyprostaglandin dehydrogenase that inhibits endothelial cell proliferation
Q360763645-lipoxygenase mediates docosahexaenoyl ethanolamide and N-arachidonoyl-L-alanine-induced reactive oxygen species production and inhibition of proliferation of head and neck squamous cell carcinoma cells
Q37187622A broad-spectrum lipidomics screen of antiinflammatory drug combinations in human blood
Q34225293Cyclooxygenase- and lipoxygenase-mediated DNA damage
Q33747062Stable-isotope dilution LC–MS for quantitative biomarker analysis
Q38222606Targeted chiral analysis of bioactive arachidonic Acid metabolites using liquid-chromatography-mass spectrometry
Q33443229Targeted chiral lipidomics analysis of bioactive eicosanoid lipids in cellular systems

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