Nitroxyl (HNO): the Cinderella of the nitric oxide story

scientific article published on October 2008

Nitroxyl (HNO): the Cinderella of the nitric oxide story is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1016/J.TIPS.2008.08.005
P698PubMed publication ID18835046

P2093author name stringRebecca H Ritchie
Jennifer C Irvine
Karen L Andrews
Barbara K Kemp-Harper
Joanne L Favaloro
Robert E Widdop
P433issue12
P304page(s)601-608
P577publication date2008-10-01
P1433published inTrends in Pharmacological SciencesQ2451474
P1476titleNitroxyl (HNO): the Cinderella of the nitric oxide story
P478volume29

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cites work (P2860)
Q51647897A FRET-based ratiometric two-photon fluorescent probe for dual-channel imaging of nitroxyl in living cells and tissues.
Q64927542A Mononuclear, Nonheme FeII-Piloty's Acid (PhSO2NHOH) Adduct: An Intermediate in the Production of {FeNO}7/8 Complexes from Piloty's Acid.
Q38693298A Phase 2a dose-escalation study of the safety, tolerability, pharmacokinetics and haemodynamic effects of BMS-986231 in hospitalized patients with heart failure with reduced ejection fraction.
Q26824749A critical review of pharmacological significance of Hydrogen Sulfide in hypertension
Q39000913A fast-response, highly sensitive and selective fluorescent probe for the ratiometric imaging of nitroxyl in living cells
Q46725818A near-infrared fluorescent probe for the selective detection of HNO in living cells and in vivo
Q42116696A novel role for HNO in local and spreading vasodilatation in rat mesenteric resistance arteries.
Q88956991A recent history of nitroxyl chemistry, pharmacology and therapeutic potential
Q37255292A role for nitroxyl (HNO) as an endothelium-derived relaxing and hyperpolarizing factor in resistance arteries.
Q41839668A selective phosphine-based fluorescent probe for nitroxyl in living cells
Q27002433A tale of two gases: NO and H2S, foes or friends for life?
Q58205578A thermally stable {FeNO}8complex: properties and biological reactivity of reduced MNO systems
Q34586679Acyloxy nitroso compounds as nitroxyl (HNO) donors: kinetics, reactions with thiols, and vasodilation properties
Q38959942Agents with vasodilator properties in acute heart failure
Q38613516Angeli's Salt, a nitroxyl anion donor, reverses endothelin-1 mediated vascular dysfunction in murine aorta
Q41903293Aorta from angiotensin II hypertensive mice exhibit preserved nitroxyl anion mediated relaxation responses
Q43239804Arylazoamidoximes and related compounds as NO-modulators.
Q37851240Cardiac inotropes: current agents and future directions
Q42720847Comparison of Reductive Ligation-Based Detection Strategies for Nitroxyl (HNO) and S-Nitrosothiols
Q36301582Design and Synthesis of Near-infrared Fluorescent Probes for Imaging of Biological Nitroxyl.
Q42681487Direct and nitroxyl (HNO)-mediated reactions of acyloxy nitroso compounds with the thiol-containing proteins glyceraldehyde 3-phosphate dehydrogenase and alkyl hydroperoxide reductase subunit C.
Q40434222Direct detection of nitroxyl in aqueous solution using a tripodal copper(II) BODIPY complex
Q38597441Discriminative EPR detection of NO and HNO by encapsulated nitronyl nitroxides.
Q37728969Endothelium-derived hyperpolarising factors and associated pathways: a synopsis
Q37438138Enzymatic generation of the NO/HNO-releasing IPA/NO anion at controlled rates in physiological media using β-galactosidase
Q52646346Evaluation of nitroxyl donors' effect on mycobacteria.
Q88955948Extension of C. elegans lifespan using the ·NO-delivery dinitrosyl iron complexes
Q43755565HNO/cGMP-dependent antihypertrophic actions of isopropylamine-NONOate in neonatal rat cardiomyocytes: potential therapeutic advantages of HNO over NO.
Q42957349Hydrogen sulfide interacts with nitric oxide in the heart: possible involvement of nitroxyl
Q39234570Hydroxylamine acutely activates glucose uptake in L929 fibroblast cells
Q55039748Influences of the heme-lysine crosslink in cytochrome P460 over redox catalysis and nitric oxide sensitivity.
Q59726944Kinetic and Mechanistic Studies on the Reactions of the Reduced Vitamin B12 Complex Cob(I)alamin with Nitrite and Nitrate
Q50763935Mechanistic studies of the reactions of the reduced vitamin B12 derivatives with the HNO donor Piloty's acid: further evidence for oxidation of cob(I)alamin by (H)NO.
Q48047879Modeling of S-Nitrosothiol-Thiol Reactions of Biological Significance: HNO Production by S-Thiolation Requires a Proton Shuttle and Stabilization of Polar Intermediates
Q47669705NO and HNO donors, nitrones, and nitroxides: Past, present, and future
Q36011399New acyloxy nitroso compounds with improved water solubility and nitroxyl (HNO) release kinetics and inhibitors of platelet aggregation
Q51308937New dinitrosyl iron complexes bound with physiologically active dipeptide carnosine.
Q37887771Nitric oxide: a guardian for vascular grafts?
Q39425650Nitroxyl (HNO) acutely activates the glucose uptake activity of GLUT1.
Q34738088Nitroxyl (HNO) reacts with molecular oxygen and forms peroxynitrite at physiological pH. Biological Implications.
Q34233761Nitroxyl (HNO) stimulates soluble guanylyl cyclase to suppress cardiomyocyte hypertrophy and superoxide generation
Q26771830Nitroxyl (HNO): A Reduced Form of Nitric Oxide with Distinct Chemical, Pharmacological, and Therapeutic Properties
Q43097999Nitroxyl anion--the universal signalling partner of endogenously produced nitric oxide?
Q39995085Nitroxyl as a ligand in ruthenium tetraammine systems: a density functional theory study
Q37142767Nitroxyl donors retain their depressor effects in hypertension.
Q33925515Nitroxyl inhibits overt pain-like behavior in mice: role of cGMP/PKG/ATP-sensitive potassium channel signaling pathway
Q41283236Nitroxyl, redox switches, cardiac myofilaments, and heart failure: a prequel to novel therapeutics?
Q49739561Nitroxyl, the novel redox sibling of NO, suppresses cerebrovascular NADPH oxidase.
Q46241410NitroxylFluor: A Thiol-Based Fluorescent Probe for Live-Cell Imaging of Nitroxyl.
Q26765793Novel Perspectives in Redox Biology and Pathophysiology of Failing Myocytes: Modulation of the Intramyocardial Redox Milieu for Therapeutic Interventions-A Review Article from the Working Group of Cardiac Cell Biology, Italian Society of Cardiology
Q62390869O2-Functionalized Methylamine Diazeniumdiolates: Evidence for E ⇄ Z Equilibration in an Acyclic System
Q36573243Pharmacological characterization of 1-nitrosocyclohexyl acetate, a long-acting nitroxyl donor that shows vasorelaxant and antiaggregatory effects.
Q37233345Potential biological chemistry of hydrogen sulfide (H2S) with the nitrogen oxides
Q34160436Proton-induced reactivity of NO⁻ from a {CoNO}⁸ complex
Q39340228Ratiometric Fluorescent Probes for the Detection of Reactive Oxygen Species
Q34030551Reactions of HNO with heme proteins: new routes to HNO-heme complexes and insight into physiological effects.
Q37010822Recent advances in the chemical biology of nitroxyl (HNO) detection and generation
Q46104588Redox variants of NO (NO⋅ and HNO) elicit vasorelaxation of resistance arteries via distinct mechanisms
Q36351009Ring expansions of acyloxy nitroso compounds
Q58766337Role of Nitric Oxide in the Cardiovascular and Renal Systems
Q38227299Ruthenium complexes as NO donors for vascular relaxation induction
Q84524033S-nitrosothiol chemistry at the single-molecule level
Q37767680Sickle cell anemia and vascular dysfunction: the nitric oxide connection
Q28833738Signaling and stress: The redox landscape in NOS2 biology
Q38843402Stem cells and diabetic cardiomyopathy: from pathology to therapy
Q39037342Sulfonimidamides in Medicinal and Agricultural Chemistry
Q41877565Synthesis of Nitric Oxide Donors Derived from Piloty's Acid and Study of Their Effects on Dopamine Secretion from PC12 Cells
Q38935734The chemical biology of HNO signaling
Q35040403The chemistry of nitroxyl-releasing compounds
Q37665613The concomitant coronary vasodilator and positive inotropic actions of the nitroxyl donor Angeli's salt in the intact rat heart: contribution of soluble guanylyl cyclase-dependent and -independent mechanisms.
Q37281633The effects of nitroxyl (HNO) on H₂O₂ metabolism and possible mechanisms of HNO signaling
Q33580106The nitric oxide-cGKII system relays death and survival signals during embryonic retinal development via AKT-induced CREB1 activation
Q36884713The nitroxyl donor, Angeli's salt, inhibits inflammatory hyperalgesia in rats
Q42365805The nitroxyl donor, Angeli's salt, reduces chronic constriction injury-induced neuropathic pain
Q93551245The novel NO redox sibling, nitroxyl (HNO), prevents cardiomyocyte hypertrophy and superoxide generation via cGMP
Q38827338Therapeutic Potential of Nitroxyl (HNO) Donors in the Management of Acute Decompensated Heart Failure
Q37725077Vascular dysfunction in cerebrovascular disease: mechanisms and therapeutic intervention
Q39722744Vasorelaxant and antiaggregatory actions of the nitroxyl donor isopropylamine NONOate are maintained in hypercholesterolemia
Q38950500Visualization of nitroxyl (HNO) in vivo via a lysosome-targetable near-infrared fluorescent probe
Q42403629Water soluble acyloxy nitroso compounds: HNO release and reactions with heme and thiol containing proteins
Q37276166cGMP does not activate two-pore domain K+ channels in cerebrovascular smooth muscle

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