Advances in oncolytic virus therapy for glioma

scientific article published on January 2009

Advances in oncolytic virus therapy for glioma is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.2174/157488909787002573
P932PMC publication ID2720101
P698PubMed publication ID19149710
P5875ResearchGate publication ID23796808

P2093author name stringChristopher Alvarez-Breckenridge
Abhik Ray Chaudhury
Balveen Kaur
Amy Haseley
P2860cites workSelective in vitro replication of herpes simplex virus type 1 (HSV-1) ICP34.5 null mutants in primary human CNS tumours--evaluation of a potentially effective clinical therapyQ24679781
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The potential for efficacy of the modified (ICP 34.5(-)) herpes simplex virus HSV1716 following intratumoural injection into human malignant glioma: a proof of principle studyQ34124333
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Treatment of intracranial gliomas in immunocompetent mice using herpes simplex viruses that express murine interleukinsQ34463480
A phase I study of OncoVEXGM-CSF, a second-generation oncolytic herpes simplex virus expressing granulocyte macrophage colony-stimulating factor.Q34583808
Multimutated herpes simplex virus g207 is a potent inhibitor of angiogenesis.Q34928710
Cyclophosphamide enhances glioma virotherapy by inhibiting innate immune responsesQ35036505
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Myxoma virus expressing human interleukin-12 does not induce myxomatosis in European rabbitsQ36315458
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Targeted cancer gene therapy using a hypoxia inducible factor dependent oncolytic adenovirus armed with interleukin-4Q36488714
Gene therapeutics: the future of brain tumor therapy?Q36532106
ICP34.5 mutants of herpes simplex virus type 1 strain 17syn+ are attenuated for neurovirulence in mice and for replication in confluent primary mouse embryo cell culturesQ36618750
Clinical trial results with oncolytic virotherapy: a century of promise, a decade of progressQ36720873
Herpes simplex virus type 1-induced ribonucleotide reductase activity is dispensable for virus growth and DNA synthesis: isolation and characterization of an ICP6 lacZ insertion mutantQ36826076
Reovirus and tumor oncolysis.Q36873392
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Intratumoral coadministration of hyaluronidase enzyme and oncolytic adenoviruses enhances virus potency in metastatic tumor modelsQ39971666
Effect of tumor microenvironment modulation on the efficacy of oncolytic virus therapyQ40043828
Matrix metalloproteinases-1 and -8 improve the distribution and efficacy of an oncolytic virusQ40050687
Examination of the therapeutic potential of Delta-24-RGD in brain tumor stem cells: role of autophagic cell deathQ40082305
Relaxin-expressing, fiber chimeric oncolytic adenovirus prolongs survival of tumor-bearing miceQ40136491
A new recombinant vaccinia with targeted deletion of three viral genes: its safety and efficacy as an oncolytic virusQ40176322
VEGF-specific short hairpin RNA-expressing oncolytic adenovirus elicits potent inhibition of angiogenesis and tumor growth.Q40181533
Oncolytic HSV and erlotinib inhibit tumor growth and angiogenesis in a novel malignant peripheral nerve sheath tumor xenograft modelQ40181544
Angiogenic response caused by oncolytic herpes simplex virus-induced reduced thrombospondin expression can be prevented by specific viral mutations or by administering a thrombospondin-derived peptideQ40181756
Effects of intravenously administered recombinant vesicular stomatitis virus (VSV(deltaM51)) on multifocal and invasive gliomas.Q40213652
Oncolytic HSV armed with platelet factor 4, an antiangiogenic agent, shows enhanced efficacy.Q40219504
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Development of a rapid method to generate multiple oncolytic HSV vectors and their in vivo evaluation using syngeneic mouse tumor modelsQ40327891
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RAD001 (everolimus) improves the efficacy of replicating adenoviruses that target colon cancerQ40390369
Stability of lentiviral vector-mediated transgene expression in the brain in the presence of systemic antivector immune responsesQ40413612
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Phase I/II trial of intravenous NDV-HUJ oncolytic virus in recurrent glioblastoma multiformeQ40495113
Angiogenesis inhibition by an oncolytic herpes virus expressing interleukin 12.Q40538206
Low-dose vaccinia virus-mediated cytokine gene therapy of gliomaQ40824587
Vesicular stomatitis virus (VSV) therapy of tumorsQ40826109
Evaluation of combined vaccinia virus-mediated antitumor gene therapy with p53, IL-2, and IL-12 in a glioma modelQ40835797
Therapeutic efficiency of IL-2 gene transduced tumor vaccine for head and neck carcinomaQ40885287
Oncolytic activity of vesicular stomatitis virus is effective against tumors exhibiting aberrant p53, Ras, or myc function and involves the induction of apoptosisQ40906922
Intraperitoneal delivery of hrR3 and ganciclovir prolongs survival in mice with disseminated pancreatic cancerQ40917912
Therapy of a murine model of pediatric brain tumors using a herpes simplex virus type-1 ICP34.5 mutant and demonstration of viral replication within the CNS.Q41148859
Treatment of malignant gliomas using ganciclovir-hypersensitive, ribonucleotide reductase-deficient herpes simplex viral mutantQ41451279
A phase I open-label, dose-escalation, multi-institutional trial of injection with an E1B-Attenuated adenovirus, ONYX-015, into the peritumoral region of recurrent malignant gliomas, in the adjuvant setting.Q42639115
Defective translational control facilitates vesicular stomatitis virus oncolysisQ42831942
Use of viral fusogenic membrane glycoproteins as novel therapeutic transgenes in gliomasQ43599287
Oncolysis by viral replication and inhibition of angiogenesis by a replication-conditional herpes simplex virus that expresses mouse endostatinQ44110160
Combined treatment of pediatric high-grade glioma with the oncolytic viral strain MTH-68/H and oral valproic acidQ44135421
Preclinical Characterization of the Antiglioma Activity of a Tropism-Enhanced Adenovirus Targeted to the Retinoblastoma PathwayQ44432093
Mapping of herpes simplex virus-1 neurovirulence to gamma 134.5, a gene nonessential for growth in cultureQ44460699
Use of Newcastle disease virus vaccine (MTH-68/H) in a patient with high-grade glioblastomaQ44685850
Pretreatment with protease is a useful experimental strategy for enhancing adenovirus-mediated cancer gene therapyQ45180665
Oncolytic herpes virus with defective ICP6 specifically replicates in quiescent cells with homozygous genetic mutations in p16.Q45396446
Degradation of fibrillar collagen in a human melanoma xenograft improves the efficacy of an oncolytic herpes simplex virus vectorQ45419303
Use of a vaccine strain of measles virus genetically engineered to produce carcinoembryonic antigen as a novel therapeutic agent against glioblastoma multiformeQ45723594
Viral shedding and biodistribution of G207, a multimutated, conditionally replicating herpes simplex virus type 1, after intracerebral inoculation in aotus.Q45739296
Systemic antitumor immunity in experimental brain tumor therapy using a multimutated, replication-competent herpes simplex virusQ45745964
Vaccinia virus-mediated expression of wild-type p53 suppresses glioma cell growth and induces apoptosis.Q45750082
Evaluation of radiation effects against C6 glioma in combination with vaccinia virus-p53 gene therapyQ45753459
Complete regression of human neuroblastoma xenografts in athymic mice after local Newcastle disease virus therapyQ45780980
Pre-treatment with elastase improves the efficiency of percutaneous adenovirus-mediated gene transfer to the arterial mediaQ45858154
Relaxin expression from tumor-targeting adenoviruses and its intratumoral spread, apoptosis induction, and efficacyQ45863191
Newcastle disease virus selectively kills human tumor cellsQ45865340
Treatment of metastatic renal cancer with capsid-modified oncolytic adenovirusesQ45871953
HSV1716 persistence in primary human glioma cells in vitroQ45888466
Glioma virotherapy: effects of innate immune suppression and increased viral replication capacityQ48643464
ICOVIR-5 shows E2F1 addiction and potent antiglioma effect in vivo.Q52291792
A mutant oncolytic adenovirus targeting the Rb pathway produces anti-glioma effect in vivo.Q52537791
MTH-68/H oncolytic viral treatment in human high-grade gliomas.Q53347956
A phase I trial of intratumoral administration of reovirus in patients with histologically confirmed recurrent malignant gliomas.Q55467147
Oncolytic activity of the E1B-55 kDa-deleted adenovirus ONYX-015 is independent of cellular p53 status in human malignant glioma xenografts.Q55473726
Therapeutic role of measles vaccine in Hodgkin's diseaseQ72720992
HSV-1 therapy of primary tumors reduces the number of metastases in an immune-competent model of metastatic breast cancerQ79124523
Oncolytic HSV exerts direct antiangiogenic activity in ovarian carcinomaQ81859838
P433issue1
P921main subjectoncolytic virusQ1560099
P304page(s)1-13
P577publication date2009-01-01
P1433published inRecent patents on CNS drug discoveryQ26842296
P1476titleAdvances in oncolytic virus therapy for glioma
P478volume4

Reverse relations

cites work (P2860)
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