Kindred S thyroid hormone receptor is an active and constitutive silencer and a repressor for thyroid hormone and retinoic acid responses

scientific article published on November 15, 1992

Kindred S thyroid hormone receptor is an active and constitutive silencer and a repressor for thyroid hormone and retinoic acid responses is …
instance of (P31):
scholarly articleQ13442814

External links are
P819ADS bibcode1992PNAS...8910633B
P356DOI10.1073/PNAS.89.22.10633
P953full work available at URLhttps://europepmc.org/articles/PMC50395
https://europepmc.org/articles/PMC50395?pdf=render
P932PMC publication ID50395
P698PubMed publication ID1359543
P5875ResearchGate publication ID21795253

P50authorBert W. O'MalleyQ827492
Ming-Jer TsaiQ90840739
Sophia Y TsaiQ90840742
P2093author name stringM. J. Tsai
A. Baniahmad
P2860cites workRegulation of two c-erbA messenger ribonucleic acids in rat GH3 cells by thyroid hormoneQ69924070
Syndromes of thyroid hormone resistanceQ72948360
A transferable silencing domain is present in the thyroid hormone receptor, in the v-erbA oncogene product and in the retinoic acid receptorQ24555696
A base mutation of the C-erbA beta thyroid hormone receptor in a kindred with generalized thyroid hormone resistance. Molecular heterogeneity in two other kindredsQ24624938
The protein Id: a negative regulator of helix-loop-helix DNA binding proteinsQ28237471
A homozygous deletion in the c-erbA beta thyroid hormone receptor gene in a patient with generalized thyroid hormone resistance: isolation and characterization of the mutant receptorQ28302131
Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin D3 receptorsQ29615768
Trans-activation by thyroid hormone receptors: functional parallels with steroid hormone receptors.Q33855825
Familial syndrome combining deaf-mutism, stuppled epiphyses, goiter and abnormally high PBI: possible target organ refractoriness to thyroid hormoneQ34203456
v-erbA oncogene activation entails the loss of hormone-dependent regulator activity of c-erbA.Q35000459
Molecular diagnosis and characterization of thyroid hormone resistance syndromesQ36474441
Ontogeny of the v-erbA oncoprotein from the thyroid hormone receptor: an alteration in the DNA binding domain plays a role crucial for v-erbA functionQ36684411
Transcriptional repression in eukaryotesQ37941786
Modular structure of a chicken lysozyme silencer: involvement of an unusual thyroid hormone receptor binding siteQ38340913
Requirement for the C-terminal domain of the v-erbA oncogene protein for biological function and transcriptional repressionQ38341818
Transcriptional repression of eukaryotic promotersQ38365817
Thyroid hormone resistance syndrome. Inhibition of normal receptor function by mutant thyroid hormone receptorsQ40348625
Activity of two different silencer elements of the chicken lysozyme gene can be compensated by enhancer elementsQ41347641
Tight linkage between the syndrome of generalized thyroid hormone resistance and the human c-erbA beta geneQ41348118
Regulation of progesterone receptor-mediated transcription by phosphorylationQ41710148
The thyroid hormone receptor binds with opposite transcriptional effects to a common sequence motif in thyroid hormone and estrogen response elementsQ43679715
Functional domains of the human glucocorticoid receptorQ43734761
Protein encoded by v-erbA functions as a thyroid-hormone receptor antagonistQ44537287
Identification of a thyroid hormone receptor that is pituitary-specificQ44748833
Familial generalized resistance to thyroid hormones: report of three kindreds and correlation of patterns of affected tissues with the binding of [125I] triiodothyronine to fibroblast nucleiQ45046838
Dual regulatory role for thyroid-hormone receptors allows control of retinoic-acid receptor activityQ45217737
Homozygosity for a Dominant Negative Thyroid Hormone Receptor Gene Responsible for Generalized Resistance to Thyroid Hormone*Q45760645
v-erbA Oncogene function in neoplasia correlates with its ability to repress retinoic acid receptor actionQ46122290
The v-erb A oncogene causes repression of erythrocyte-specific genes and an immature, aberrant differentiation phenotype in normal erythroid progenitors.Q53505031
Variable transcriptional activity and ligand binding of mutant beta 1 3,5,3'-triiodothyronine receptors from four families with generalized resistance to thyroid hormone.Q54276254
Expression of the v-erbA product, an altered nuclear hormone receptor, is sufficient to transform erythrocytic cells in vitro.Q54348884
A mechanism for synergistic activation of a mammalian gene by GAL4 derivatives.Q54713263
Repression of transcription mediated at a thyroid hormone response element by the v-erb-A oncogene productQ59098062
Mutations that alter both localization and production of a yeast nuclear proteinQ61631665
P433issue22
P407language of work or nameEnglishQ1860
P921main subjecttretinoinQ29417
transcriptionQ177900
P304page(s)10633-10637
P577publication date1992-11-01
1992-11-15
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleKindred S thyroid hormone receptor is an active and constitutive silencer and a repressor for thyroid hormone and retinoic acid responses
P478volume89

Reverse relations

cites work (P2860)
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Q35885778A composite intragenic silencer domain exhibits negative and positive transcriptional control of the bone-specific osteocalcin gene: promoter and cell type requirements
Q33844628A highly selective, label-free, homogenous luminescent switch-on probe for the detection of nanomolar transcription factor NF-kappaB.
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