| scholarly article | Q13442814 |
| P50 | author | Roderick H Dashwood | Q92334921 |
| P2093 | author name string | Hui Nian | |
| John T Pinto | |||
| Barbara Delage | |||
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| The determination of enzyme inhibitor constants | Q29618526 | ||
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| Frequent epigenetic inactivation of Wnt inhibitory factor-1 in human gastrointestinal cancers. | Q34432769 | ||
| Acetylation of p53 at lysine 373/382 by the histone deacetylase inhibitor depsipeptide induces expression of p21(Waf1/Cip1). | Q34520098 | ||
| Fruit and vegetable intake and prevalence of colorectal adenoma in a cancer screening trial | Q34585871 | ||
| Histone deacetylase inhibitors prevent oxidative neuronal death independent of expanded polyglutamine repeats via an Sp1-dependent pathway | Q34923735 | ||
| Design of Specific Inhibitors of Angiotensin-Converting Enzyme: New Class of Orally Active Antihypertensive Agents | Q34936463 | ||
| The interaction of histone deacetylase inhibitors and DNA methyltransferase inhibitors in the treatment of human cancer cells. | Q35137797 | ||
| Epigenetic changes in colorectal cancer. | Q35682096 | ||
| Transcriptional signature of histone deacetylase inhibition in multiple myeloma: biological and clinical implications | Q35734509 | ||
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| Histone deacetylase inhibitors open new doors in cancer therapy | Q35864048 | ||
| Signal transduction pathways leading to cell cycle arrest and apoptosis induction in cancer cells by Allium vegetable-derived organosulfur compounds: a review | Q35914361 | ||
| Dietary cancer-chemopreventive compounds: from signaling and gene expression to pharmacological effects | Q36145133 | ||
| Allyl sulfur compounds from garlic modulate aberrant crypt formation | Q36399290 | ||
| Histone deacetylases as targets for dietary cancer preventive agents: lessons learned with butyrate, diallyl disulfide, and sulforaphane | Q36447045 | ||
| Sulforaphane retards the growth of human PC-3 xenografts and inhibits HDAC activity in human subjects. | Q36496614 | ||
| Sulforaphane inhibits histone deacetylase activity in BPH-1, LnCaP and PC-3 prostate epithelial cells | Q36512713 | ||
| Cancer chemoprevention with garlic and its constituents | Q36515649 | ||
| Restoration of wild-type p53 function in human cancer: relevance for tumor therapy. | Q36710840 | ||
| Dietary components impact histone modifications and cancer risk | Q36754379 | ||
| Mechanisms of resistance to histone deacetylase inhibitors and their therapeutic implications | Q37038216 | ||
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| Both Sp1 and Sp3 are responsible for p21waf1 promoter activity induced by histone deacetylase inhibitor in NIH3T3 cells | Q38324898 | ||
| Trichostatin A induces transforming growth factor beta type II receptor promoter activity and acetylation of Sp1 by recruitment of PCAF/p300 to a Sp1.NF-Y complex | Q38332130 | ||
| Expression of p21(WAF1/Cip1) through Sp1 sites by histone deacetylase inhibitor apicidin requires PI 3-kinase-PKC epsilon signaling pathway | Q38350788 | ||
| DNA demethylation and histone deacetylation inhibition co-operate to re-express estrogen receptor beta and induce apoptosis in prostate cancer cell-lines | Q40033345 | ||
| Histone deacetylase inhibitor, suberoylanilide hydroxamic acid (Vorinostat, SAHA) profoundly inhibits the growth of human pancreatic cancer cells | Q40148122 | ||
| Site-specific acetylation of p53 directs selective transcription complex assembly. | Q40205369 | ||
| Effects of histone deacetylase inhibitors on p55CDC/Cdc20 expression in HT29 cell line. | Q40263409 | ||
| c-Jun NH(2)-terminal kinase signaling axis regulates diallyl trisulfide-induced generation of reactive oxygen species and cell cycle arrest in human prostate cancer cells | Q40278650 | ||
| Protective effects of garlic sulfur compounds against DNA damage induced by direct- and indirect-acting genotoxic agents in HepG2 cells | Q40295924 | ||
| Immunohistochemical analysis of acetylation, proliferation, mitosis, and apoptosis in tumor xenografts following administration of a histone deacetylase inhibitor--a pilot study | Q40334140 | ||
| Depletion of mutant p53 and cytotoxicity of histone deacetylase inhibitors | Q40384723 | ||
| Checkpoint kinase 1 regulates diallyl trisulfide-induced mitotic arrest in human prostate cancer cells | Q40408481 | ||
| Novel inhibitors of human histone deacetylases: design, synthesis, enzyme inhibition, and cancer cell growth inhibition of SAHA-based non-hydroxamates. | Q40457501 | ||
| Sp3, but not Sp1, mediates the transcriptional activation of the p21/WAF1/Cip1 gene promoter by histone deacetylase inhibitor. | Q40929256 | ||
| Histone deacetylase 3 (HDAC3) and other class I HDACs regulate colon cell maturation and p21 expression and are deregulated in human colon cancer | Q42492006 | ||
| Induction of histone acetylation in mouse erythroleukemia cells by some organosulfur compounds including allyl isothiocyanate | Q43606512 | ||
| Induction of histone acetylation and inhibition of growth of mouse erythroleukemia cells by S-allylmercaptocysteine | Q44239145 | ||
| Gene expression profiling of multiple histone deacetylase (HDAC) inhibitors: defining a common gene set produced by HDAC inhibition in T24 and MDA carcinoma cell lines | Q44317132 | ||
| Acetylated sp3 is a transcriptional activator | Q44499415 | ||
| Garlic attenuates chrysotile-mediated pulmonary toxicity in rats by altering the phase I and phase II drug metabolizing enzyme system | Q44715773 | ||
| Acetylation of histones associated with the p21WAF1/CIP1 gene by butyrate is not sufficient for p21WAF1/CIP1 gene transcription in human colorectal adenocarcinoma cells | Q44747129 | ||
| Diallyl disulfide (DADS) increases histone acetylation and p21(waf1/cip1) expression in human colon tumor cell lines | Q44771633 | ||
| Thiol-based SAHA analogues as potent histone deacetylase inhibitors | Q44900745 | ||
| Structural snapshots of human HDAC8 provide insights into the class I histone deacetylases | Q44970107 | ||
| A novel mechanism of chemoprotection by sulforaphane: inhibition of histone deacetylase. | Q45020400 | ||
| Induction of detoxifying enzymes by garlic organosulfur compounds through transcription factor Nrf2: effect of chemical structure and stress signals. | Q45100925 | ||
| p21Waf1/Cip1 is a common target induced by short-chain fatty acid HDAC inhibitors (valproic acid, tributyrin and sodium butyrate) in neuroblastoma cells. | Q46471892 | ||
| Modulation of cytochrome P450 enzymes by organosulfur compounds from garlic | Q46586329 | ||
| P433 | issue | 9 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | garlic | Q21546392 |
| P304 | page(s) | 1816-1824 | |
| P577 | publication date | 2008-07-14 | |
| P1433 | published in | Carcinogenesis | Q326022 |
| P1476 | title | Allyl mercaptan, a garlic-derived organosulfur compound, inhibits histone deacetylase and enhances Sp3 binding on the P21WAF1 promoter | |
| P478 | volume | 29 |
| Q37705112 | Allyl sulfur compounds and cellular detoxification system: effects and perspectives in cancer therapy |
| Q33985807 | Alpha-keto acid metabolites of naturally occurring organoselenium compounds as inhibitors of histone deacetylase in human prostate cancer cells |
| Q37281699 | Alpha-keto acid metabolites of organoselenium compounds inhibit histone deacetylase activity in human colon cancer cells |
| Q36727361 | Anabolic and Antiresorptive Modulation of Bone Homeostasis by the Epigenetic Modulator Sulforaphane, a Naturally Occurring Isothiocyanate |
| Q37628348 | Butyrate Inhibits Cancerous HCT116 Colon Cell Proliferation but to a Lesser Extent in Noncancerous NCM460 Colon Cells |
| Q34279875 | Cancer chemoprevention by dietary polyphenols: promising role for epigenetics |
| Q35928052 | Chemoprevention in gastrointestinal physiology and disease. Targeting the progression of cancer with natural products: a focus on gastrointestinal cancer |
| Q34249695 | Chemopreventive mechanisms of α-keto acid metabolites of naturally occurring organoselenium compounds |
| Q95280353 | Design and in silico screening of aryl allyl mercaptan analogs as potential histone deacetylases (HDAC) inhibitors |
| Q38012499 | Developing histone deacetylase inhibitors in the therapeutic armamentarium of pancreatic adenocarcinoma. |
| Q48336312 | Diallyl trisulfides, a natural histone deacetylase inhibitor, attenuate HIF-1α synthesis, and decreases breast cancer metastasis |
| Q26991774 | Dietary factors and epigenetic regulation for prostate cancer prevention |
| Q34898711 | Dietary manipulation of histone structure and function |
| Q84144610 | Dietary manipulation of histone structure and function |
| Q38818485 | Dietary phytochemicals as epigenetic modifiers in cancer: Promise and challenges |
| Q28257534 | Dietary phytochemicals, HDAC inhibition, and DNA damage/repair defects in cancer cells |
| Q21296850 | Dietary, metabolic, and potentially environmental modulation of the lysine acetylation machinery |
| Q39317906 | E-Cadherin/β-Catenin Complex: A Target for Anticancer and Antimetastasis Plants/Plant-derived Compounds |
| Q92113302 | Epigenetic Gene Regulation by Dietary Compounds in Cancer Prevention |
| Q36925753 | Epigenetic Upregulation of Metallothionein 2A by Diallyl Trisulfide Enhances Chemosensitivity of Human Gastric Cancer Cells to Docetaxel Through Attenuating NF-κB Activation |
| Q34180255 | Epigenetic changes induced by curcumin and other natural compounds. |
| Q27022002 | Epigenetic diet: impact on the epigenome and cancer |
| Q33587441 | Epigenetic mechanisms underlying diet-sourced compounds in the prevention and treatment of gastrointestinal cancer |
| Q39281746 | Epigenetic modifications and p21-cyclin B1 nexus in anticancer effect of histone deacetylase inhibitors in combination with silibinin on non-small cell lung cancer cells |
| Q34339224 | Epigenetic regulation by selected dietary phytochemicals in cancer chemoprevention |
| Q38126096 | Epigenetics: a new link between nutrition and cancer |
| Q26823403 | Epigenomics of leukemia: from mechanisms to therapeutic applications |
| Q30358087 | H2S-releasing nanoemulsions: a new formulation to inhibit tumor cells proliferation and improve tissue repair. |
| Q42703854 | HDAC8 and STAT3 repress BMF gene activity in colon cancer cells |
| Q38572921 | Histone and Non-Histone Targets of Dietary Deacetylase Inhibitors |
| Q35214924 | Histone deacetylase inhibitors in clinical studies as templates for new anticancer agents |
| Q64283126 | Histone deacetylase inhibitory and cytotoxic activities of the constituents from the roots of three species of |
| Q36049516 | Histone deacetylase modulators provided by Mother Nature |
| Q30431647 | Histone deacetylase turnover and recovery in sulforaphane-treated colon cancer cells: competing actions of 14-3-3 and Pin1 in HDAC3/SMRT corepressor complex dissociation/reassembly |
| Q47206394 | Mass Spectrometry Imaging of low Molecular Weight Compounds in Garlic (Allium sativum L.) with Gold Nanoparticle Enhanced Target |
| Q35661981 | Metabolism as a key to histone deacetylase inhibition |
| Q37240767 | Modulation of histone deacetylase activity by dietary isothiocyanates and allyl sulfides: studies with sulforaphane and garlic organosulfur compounds |
| Q92129314 | Natural Hydrogen Sulfide Donors from Allium sp. as a Nutraceutical Approach in Type 2 Diabetes Prevention and Therapy |
| Q37114055 | Natural compound-derived epigenetic regulators targeting epigenetic readers, writers and erasers |
| Q34494941 | Nrf2 status affects tumor growth, HDAC3 gene promoter associations, and the response to sulforaphane in the colon |
| Q34271529 | Plant HDAC inhibitor chrysin arrest cell growth and induce p21WAF1 by altering chromatin of STAT response element in A375 cells |
| Q64053408 | Prenatal epigenetics diets play protective roles against environmental pollution |
| Q37618093 | Recent Research Progress on Garlic ( dà suàn) as a Potential Anticarcinogenic Agent Against Major Digestive Cancers. |
| Q38751121 | Reciprocal regulation of BMF and BIRC5 (Survivin) linked to Eomes overexpression in colorectal cancer |
| Q58702666 | Redox Modulation at Work: Natural Phytoprotective Polysulfanes From Based on Redox-Active Sulfur |
| Q36072083 | Targeting the epigenome with bioactive food components for cancer prevention |
| Q36157305 | The histone deacetylase inhibitor trichostatin a decreases lymphangiogenesis by inducing apoptosis and cell cycle arrest via p21-dependent pathways |
| Q37651515 | Therapeutic Role of Functional Components in Alliums for Preventive Chronic Disease in Human Being |
| Q37976694 | When food meets man: the contribution of epigenetics to health. |
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