Pretargeting CD45 enhances the selective delivery of radiation to hematolymphoid tissues in nonhuman primates

scientific article published on 10 June 2009

Pretargeting CD45 enhances the selective delivery of radiation to hematolymphoid tissues in nonhuman primates is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1182/BLOOD-2009-03-210344
P932PMC publication ID2723017
P698PubMed publication ID19515724
P5875ResearchGate publication ID26281923

P2093author name stringOliver W Press
Yukang Lin
D Scott Wilbur
Donald K Hamlin
Ajay K Gopal
John M Pagel
Joseph G Rajendran
Aimee Kenoyer
Damian J Green
Darrell R Fisher
Steven I Park
Anastasia Pantelias
Eneida R Nemecek
P2860cites workInternal dosimetry for systemic radiation therapyQ33869348
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131I-anti-CD45 antibody plus busulfan and cyclophosphamide before allogeneic hematopoietic cell transplantation for treatment of acute myeloid leukemia in first remission.Q35849468
Comparison of a tetravalent single-chain antibody-streptavidin fusion protein and an antibody-streptavidin chemical conjugate for pretargeted anti-CD20 radioimmunotherapy of B-cell lymphomasQ35849837
Combining yttrium 90-labeled ibritumomab tiuxetan with high-dose chemotherapy and stem cell support in patients with relapsed non-Hodgkin's lymphoma.Q35924871
Human homologue of murine T200 glycoprotein.Q36344070
Eradication of disseminated leukemia in a syngeneic murine leukemia model using pretargeted anti-CD45 radioimmunotherapy.Q36445890
Rituximab blocks binding of radiolabeled anti-CD20 antibodies (Ab) but not radiolabeled anti-CD45 Ab.Q36787584
Pretargeted radioimmunotherapy using anti-CD45 monoclonal antibodies to deliver radiation to murine hematolymphoid tissues and human myeloid leukemia.Q37036289
Cure of human carcinoma xenografts by a single dose of pretargeted yttrium-90 with negligible toxicityQ37118311
A genetically engineered anti-CD45 single-chain antibody-streptavidin fusion protein for pretargeted radioimmunotherapy of hematologic malignancies.Q40296288
A phase 1B trial of humanized monoclonal antibody M195 (anti-CD33) in myeloid leukemia: specific targeting without immunogenicityQ40702351
Treatment approaches to the low-grade lymphomasQ40716421
CD45 (leucocyte common antigen) expression in T and B lymphocyte subsetsQ40983534
Localization of radiolabeled antimyeloid antibodies in a human acute leukemia xenograft tumor modelQ41647059
Expression of leukocyte common antigen (CD45) on various human leukemia/lymphoma cell linesQ41746312
Preclinical evaluation of a humanized NR-LU-10 antibody-streptavidin fusion protein for pretargeted cancer therapyQ43625794
Pretargeting radioimmunotherapy of a murine model of adult T-cell leukemia with the alpha-emitting radionuclide, bismuth 213.Q44031707
Radiolabeled-Antibody Therapy of B-Cell Lymphoma with Autologous Bone Marrow SupportQ44080136
Comparison of anti-CD20 and anti-CD45 antibodies for conventional and pretargeted radioimmunotherapy of B-cell lymphomas.Q44225929
Comparison of immunoscintigraphy, efficacy, and toxicity of conventional and pretargeted radioimmunotherapy in CD20-expressing human lymphoma xenografts.Q44350601
Combination therapy with Pretarget CC49 radioimmunotherapy and gemcitabine prolongs tumor doubling time in a murine xenograft model of colon cancer more effectively than either monotherapyQ44594055
Pretargeted radioimmunotherapy (PRIT) for treatment of non-Hodgkin's lymphoma (NHL): initial phase I/II study resultsQ44870094
Radiolabeled anti-CD45 monoclonal antibodies target lymphohematopoietic tissue in the macaqueQ45104917
A tetravalent single-chain antibody-streptavidin fusion protein for pretargeted lymphoma therapyQ47807458
Phase 1 trial of a novel anti-CD20 fusion protein in pretargeted radioimmunotherapy for B-cell non-Hodgkin lymphomaQ48010246
A quantitative analysis of tumor specific monoclonal antibody uptake by human melanoma xenografts: effects of antibody immunological properties and tumor antigen expression levelsQ67720697
Selective radiation of hematolymphoid tissue delivered by anti-CD45 antibodyQ68052741
Monoclonal antibody 1F5 (anti-CD20) serotherapy of human B cell lymphomasQ68812167
Antibody-radionuclide conjugates as part of a myeloablative preparative regimen for marrow transplantationQ69506136
Treatment of refractory non-Hodgkin's lymphoma with radiolabeled MB-1 (anti-CD37) antibodyQ69520763
Endocytosis and degradation of monoclonal antibodies targeting human B-cell malignanciesQ69522036
Experimental radioimmunotherapy of murine lymphoma with 131I-labeled anti-T-cell antibodiesQ69660072
Radiometal labeling of immunoproteins: covalent linkage of 2-(4-isothiocyanatobenzyl)diethylenetriaminepentaacetic acid ligands to immunoglobulinQ70290393
Development of a marrow transplant regimen for acute leukemia using targeted hematopoietic irradiation delivered by 131I-labeled anti-CD45 antibody, combined with cyclophosphamide and total body irradiationQ72529067
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The use of paired labeling in the determination of tumor-localizing antibodiesQ74642184
Follow-up of relapsed B-cell lymphoma patients treated with iodine-131-labeled anti-CD20 antibody and autologous stem-cell rescueQ77435841
Phase I study of (131)I-anti-CD45 antibody plus cyclophosphamide and total body irradiation for advanced acute leukemia and myelodysplastic syndromeQ78102284
Radioimmunotherapy: is avidin-biotin pretargeting the preferred choice among pretargeting methods?Q78948018
Biodistribution of yttrium-90-labeled anti-CD45 antibody in a nonhuman primate modelQ81383380
P433issue6
P407language of work or nameEnglishQ1860
P304page(s)1226-1235
P577publication date2009-06-10
P1433published inBloodQ885070
P1476titlePretargeting CD45 enhances the selective delivery of radiation to hematolymphoid tissues in nonhuman primates
P478volume114

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cites work (P2860)
Q37675882A preclinical model of CD38-pretargeted radioimmunotherapy for plasma cell malignancies.
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Q34039426Affinity enhancement pretargeting: synthesis and testing of a 99mTc-labeled bivalent MORF
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Q37720850Antibody vectors for imaging
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Q38799356Comparative Analysis of Bispecific Antibody and Streptavidin-Targeted Radioimmunotherapy for B-cell Cancers
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Q38096058Radioimmunotherapy for hematopoietic cell transplantation
Q93079994Therapeutic Applications of Pretargeting
Q36438435Two-Step Delivery: Exploiting the Partition Coefficient Concept to Increase Intratumoral Paclitaxel Concentrations In vivo Using Responsive Nanoparticles

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