An intrastrand d(GpG) platinum crosslink in duplex M13 DNA is refractory to repair by human cell extracts (scientific article published on November 15, 1992)

Transcription by eucaryotic and procaryotic RNA polymerases of DNA modified at a d(GG) or a d(AG) site by the antitumor drug cis-diamminedichloroplatinum(II)

Q68183300

Differential repair of platinum-DNA adducts in human bladder and testicular tumor continuous cell lines

Q68343885

Reevaluation of interaction of cis-dichloro(ethylenediamine)platinum(II) with DNA

Q69586643

In vivo effects of cis- and trans-diamminedichloroplatinum(II) on SV40 chromosomes: differential repair, DNA-protein cross-linking, and inhibition of replication

Q70126283

Increased DNA repair as a mechanism of acquired resistance to cis-diamminedichloroplatinum (II) in human ovarian cancer cell lines

Q70404759

Adducts of the antitumor drug cis-diamminedichloroplatinum(II) with DNA: formation, identification, and quantitation

Q93607580

Isolation and characterization of human cDNA clones encoding a high mobility group box protein that recognizes structural distortions to DNA caused by binding of the anticancer agent cisplatin

Q24562722

Isolation of cDNAs encoding a human protein that binds selectively to DNA modified by the anticancer drug cis-diamminedichloroplatinum(II)

Q24604428

Xeroderma pigmentosum group E cells lack a nuclear factor that binds to damaged DNA

Q28292106

Drugs five years later. Cisplatin

Q34257493

Complementation of DNA repair in xeroderma pigmentosum group A cell extracts by a protein with affinity for damaged DNA.

Q35935973

Sites of termination of in vitro DNA synthesis on cis-diamminedichloroplatinum(II) treated single-stranded DNA: a comparison between E. coli DNA polymerase I and eucaryotic DNA polymerases alpha

Q36005271

Human nucleotide excision nuclease removes thymine dimers from DNA by incising the 22nd phosphodiester bond 5' and the 6th phosphodiester bond 3' to the photodimer

Q36968114

Sequence-dependent termination of in vitro DNA synthesis by cis- and trans-diamminedichloroplatinum (II).

Q37523234

Replication inhibition and translesion synthesis on templates containing site- specifically placed cis-diamminedichloroplatinum(II) DNA adducts

Q38329239

Specific binding of chromosomal protein HMG1 to DNA damaged by the anticancer drug cisplatin

Q38329454

DNA unwinding produced by site-specific intrastrand cross-links of the antitumor drug cis-diamminedichloroplatinum(II).

Q38333904

Characterization of a DNA damage-recognition protein from mammalian cells that binds specifically to intrastrand d(GpG) and d(ApG) DNA adducts of the anticancer drug cisplatin

Q38340395

Substrate overlap and functional competition between human nucleotide excision repair and Escherichia coli photolyase and (a)BC excision nuclease

Q38340400

Bending studies of DNA site-specifically modified by cisplatin, trans-diamminedichloroplatinum(II) and cis-[Pt(NH3)2(N3-cytosine)Cl]+.

Q38341322

Chemical and biological studies of the major DNA adduct of cis-diamminedichloroplatinum(II), cis-[Pt(NH3)2(d(GpG]], built into a specific site in a viral genome

Q38347089

Human nucleotide excision repair in vitro: repair of pyrimidine dimers, psoralen and cisplatin adducts by HeLa cell-free extract.

Q40450557

Reactions of the UVRABC excision nuclease with DNA damaged by diamminedichloroplatinum(II).

Q40472204

Complementation of the xeroderma pigmentosum DNA repair synthesis defect with Escherichia coli UvrABC proteins in a cell-free system

Q40513521

Repair synthesis by human cell extracts in DNA damaged by cis- and trans-diamminedichloroplatinum(II).

Q40538207

Effect of the antitumor drug cis-diamminedichloroplatinum(II) and related platinum complexes on eukaryotic DNA replication

Q41202176

Excision repair of cis-diamminedichloroplatinum(II)-induced damage to DNA of Chinese hamster cells

Q41487235

Gene-specific formation and repair of cisplatin intrastrand adducts and interstrand cross-links in Chinese hamster ovary cells

Q41687395

Enhanced DNA repair and tolerance of DNA damage associated with resistance to cis-diammine-dichloroplatinum (II) after in vitro exposure of a human teratoma cell line to fractionated X-irradiation.

Q41728494

Localization of DNA repair synthesis by human cell extracts to a short region at the site of a lesion.

Q41757759

Identification of inducible damage-recognition proteins that are overexpressed in HeLa cells resistant to cis-diamminedichloroplatinum (II).

Q41881603

Formation and repair of cisplatin-induced adducts to DNA in cultured normal and repair-deficient human fibroblasts.

Q43484172

DNA excision repair in cell extracts from human cell lines exhibiting hypersensitivity to DNA-damaging agents

Q44551787

Enhanced DNA repair as a mechanism of resistance to cis-diamminedichloroplatinum(II).

Q52832659

Efficient synthesis of a supercoiled M13 DNA molecule containing a site specifically placed psoralen adduct and its use as a substrate for DNA replication.

Q54235179

Role of carrier ligand in platinum resistance in L1210 cells.

Q54313675

Effect of the diaminocyclohexane carrier ligand on platinum adduct formation, repair, and lethality.

Q54332081

Specific strand loss in N-2-acetylaminofluorene-modified DNA.

Q54767243

Complementation of the xeroderma pigmentosum DNA repair defect in cell-free extracts.

Q55060652

Effect of exogenous DNA fragments on human cell extract-mediated DNA repair synthesis

Q60311339

Requirement for the replication protein SSB in human DMA excision repair

Q60311342

P433

issue

P407

language of work or name

English

Q1860

P921

main subject

platinum

Q880

DNA repair

Q210538

P304

page(s)

10772-10776

P577

publication date

1992-11-01

1992-11-15

P1433

published in

Proceedings of the National Academy of Sciences of the United States of America

Q1146531

P1476

title

An intrastrand d(GpG) platinum crosslink in duplex M13 DNA is refractory to repair by human cell extracts

P478

volume

Reverse relations

cites work (P2860)

Q36785185	A new anticancer platinum compound, (-)-(R)-2-aminomethyl-pyrrolidine(1,1-cyclobutanedicarboxylato) platinum(II): DNA interstrand crosslinking, repair and lethal effects in normal human, Fanconi's anaemia and xeroderma pigmentosum cells
Q33893171	A rationally designed genotoxin that selectively destroys estrogen receptor-positive breast cancer cells
Q39715713	A repair competition assay to assess recognition by human nucleotide excision repair
Q72422002	Accumulation of platinum in the intervertebral discs and vertebrae of ovarian tumor-bearing patients treated with cisplatin
Q36566743	An XPG DNA repair defect causing mutagen hypersensitivity in mouse leukemia L1210 cells
Q28829273	An in vitro method for detecting genetic toxicity based on inhibition of RNA synthesis by DNA lesions
Q36799639	Analysis of incision sites produced by human cell extracts and purified proteins during nucleotide excision repair of a 1,3-intrastrand d(GpTpG)-cisplatin adduct
Q33649960	Biological properties of single chemical-DNA adducts: a twenty year perspective
Q84593041	Cellular uptake and cytoplasm / DNA distribution of cisplatin and oxaliplatin and their liposomal formulation in human colorectal cancer cell HCT116
Q44281098	Changes in endogenous tissue glutathione level in relation to murine ascites tumor growth and the anticancer activity of cisplatin
Q41166774	Chromatin assembly coupled to DNA repair: a new role for chromatin assembly factor I.
Q41423739	Cip1 inhibits DNA replication but not PCNA-dependent nucleotide excision-repair
Q36149816	Cisplatin damage: are DNA repair proteins saviors or traitors to the cell?
Q35518363	Cisplatin-DNA adducts are molecular decoys for the ribosomal RNA transcription factor hUBF (human upstream binding factor).
Q33635353	Current gene expression studies in esophageal carcinoma
Q33601030	DNA damage excision repair in microplate wells with chemiluminescence detection: development and perspectives.
Q37358566	DNA damage tolerance and a web of connections with DNA repair at Yale
Q34625375	Differential human nucleotide excision repair of paired and mispaired cisplatin-DNA adducts
Q54649579	Effects of a single intrastrand d(GpG) platinum adduct on the strand separating activity of the Escherichia coli proteins RecB and RecA.
Q28296085	Formation and repair of interstrand cross-links in DNA
Q35852579	HMG-domain proteins specifically inhibit the repair of the major DNA adduct of the anticancer drug cisplatin by human excision nuclease
Q24561381	High-efficiency bypass of DNA damage by human DNA polymerase Q
Q38340847	High-mobility group 1 protein inhibits helicase catalyzed displacement of cisplatin-damaged DNA.
Q54462984	Human DNA polymerase N (POLN) is a low fidelity enzyme capable of error-free bypass of 5S-thymine glycol.
Q45770163	In vitro bypass replication of the cisplatin-d(GpG) lesion by calf thymus DNA polymerase beta and human immunodeficiency virus type I reverse transcriptase is highly mutagenic
Q53712743	In vitro enhancement of antitumor activity of a water-soluble duocarmycin derivative, KW-2189, by caffeine-mediated DNA-repair inhibition in human lung cancer cells.
Q40997032	Lack of correlation between repair of DNA interstrand cross-links and hypersensitivity of hamster cells towards mitomycin C and cisplatin
Q34282241	Mechanisms of resistance to cisplatin
Q34866688	Molecular aspects of resistance to antitumor platinum drugs.
Q40400417	Mutagenesis in monkey cells of a vector containing a single d(GPG) cis-diamminedichloroplatinum(II) adduct placed on codon 13 of the human H-ras proto-oncogene
Q36591929	Overexpression of cyclin B1 antagonizes chemotherapeutic-induced apoptosis through PTEN/Akt pathway in human esophageal squamous cell carcinoma cells
Q34671647	Particular aspects of platinum compounds used at present in cancer treatment
Q30755683	Photocrosslinking locates a binding site for the large subunit of human replication protein A to the damaged strand of cisplatin-modified DNA
Q33180580	Preclinical perspectives on platinum resistance
Q73502663	Preferential formation and decreased removal of cisplatin–DNA adducts in Chinese hamster ovary cell mitochondrial DNA as compared to nuclear DNA
Q35888670	Rapid gene-specific repair of cisplatin lesions at the human DUG/DHFR locus comprising the divergent upstream gene and dihydrofolate reductase gene during early G1 phase of the cell cycle assayed by using the exonucleolytic activity of T4 DNA polyme
Q41886077	Recognition of DNA alterations by the mismatch repair system
Q36615580	Repair by human cell extracts of single (6-4) and cyclobutane thymine-thymine photoproducts in DNA
Q43875766	Repair of damaged DNA by Arabidopsis cell extract
Q44242635	Review of Cisplatin and Oxaliplatin in Current Immunogenic and Monoclonal Antibodies Perspective
Q28082382	Review of Cisplatin and oxaliplatin in current immunogenic and monoclonal antibody treatments
Q35009287	Role of the human ERCC-1 gene in gene-specific repair of cisplatin-induced DNA damage
Q34625095	Selective recognition of a cisplatin-DNA adduct by human mismatch repair proteins.
Q40707413	Studying nucleotide excision repair of mammalian DNA in a cell-free system
Q54266410	Synthesis, Characterization, and Repair of a Flexible O(6) -2'-Deoxyguanosine-alkylene-O(6) -2'-deoxyguanosine Intrastrand Cross-Link.
Q58318854	Transcription factor b (TFIIH) is required during nucleotide-excision repair in yeast
Q33878705	Up-regulation of Fas reverses cisplatin resistance of human small cell lung cancer cells
Q39936122	Vanillins--a novel family of DNA-PK inhibitors
Q24320768	XPG endonuclease makes the 3' incision in human DNA nucleotide excision repair

P819	ADS bibcode	1992PNAS...8910772S
P356	DOI	10.1073/PNAS.89.22.10772
P953	full work available at URL	https://europepmc.org/articles/PMC50424
		https://europepmc.org/articles/PMC50424?pdf=render
P932	PMC publication ID	50424
P698	PubMed publication ID	1438274
P5875	ResearchGate publication ID	21717992