Expression of ENaC subunits, chloride channels, and aquaporins in ovine fetal lung: ontogeny of expression and effects of altered fetal cortisol concentrations

scientific article published on 10 June 2009

Expression of ENaC subunits, chloride channels, and aquaporins in ovine fetal lung: ontogeny of expression and effects of altered fetal cortisol concentrations is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1152/AJPREGU.00127.2009
P932PMC publication ID2724229
P698PubMed publication ID19515987
P5875ResearchGate publication ID26282180

P2093author name stringCharles E Wood
Elaine M Richards
Maureen Keller-Wood
Xiaodi Feng
Jarret McCartney
Nathan M Jesse
P2860cites workThe alpha-subunit of the epithelial sodium channel is an aldosterone-induced transcript in mammalian collecting ducts, and this transcriptional response is mediated via distinct cis-elements in the 5'-flanking region of the geneQ28206546
Amiloride-sensitive epithelial Na+ channel is made of three homologous subunitsQ28249570
Increased airway epithelial Na+ absorption produces cystic fibrosis-like lung disease in miceQ28255797
Oxygen-evoked Na+ transport in rat fetal distal lung epithelial cellsQ28361725
Steroid and oxygen effects on eIF4F complex, mTOR, and ENaC translation in fetal lung epitheliaQ28594930
Aquaporins in complex tissues. I. Developmental patterns in respiratory and glandular tissues of ratQ28640252
Epithelial sodium channel regulated by aldosterone-induced protein sgk.Q30650629
Developmental expression of the epithelial Na+ channel in kidney and uroepithelia.Q31913371
Developmental regulation of epithelial sodium channel subunit mRNA expression in rat colon and lungQ31960142
Expression of highly selective sodium channels in alveolar type II cells is determined by culture conditionsQ32127966
Pulmonary and circulatory changes in conscious sheep exposed to 100% O2 at 1 ATA.Q33482126
Sodium channels in alveolar epithelial cells: molecular characterization, biophysical properties, and physiological significanceQ33547262
The heterotetrameric architecture of the epithelial sodium channel (ENaC).Q33888043
Aldosterone induces rapid apical translocation of ENaC in early portion of renal collecting system: possible role of SGK.Q33938102
Pharmacological and functional characterization of human mineralocorticoid and glucocorticoid receptor ligands.Q34347790
SGK1: aldosterone-induced relay of Na+ transport regulation in distal kidney nephron cellsQ35089677
Noncoordinate regulation of ENaC: paradigm lost?Q35553555
Localization of cystic fibrosis transmembrane conductance regulator mRNA in human fetal lung tissue by in situ hybridizationQ35605644
Developmental regulation of lung liquid transportQ35672494
Regulation of Na+ channels in lung alveolar type II epithelial cells.Q36236724
Physiology of fetal lung fluid clearance and the effect of laborQ36426164
Developmental Aspects of the Pituitary-Adrenal Axis Response to Hemorrhagic Stress in Lamb Fetuses In UteroQ37050961
Is the fetal lung a mineralocorticoid receptor target organ? Induction of cortisol-regulated genes in the ovine fetal lung, kidney and small intestineQ37125632
Some assembly required: putting the epithelial sodium channel togetherQ37247436
Aquaporin-1 water channel protein in lung: ontogeny, steroid-induced expression, and distribution in rat.Q37354860
Assessment of the CFTR and ENaC associationQ37373358
Blockade of estrogen receptors decreases CNS and pituitary prostaglandin synthase expression in fetal sheepQ37475423
Regulation of expression of the lung amiloride-sensitive Na+ channel by steroid hormonesQ37631862
Induction of aquaporin 1 by dexamethasone in lipid rafts in immortalized brain microvascular endothelial cellsQ40214214
Role of Nedd4-2 and polyubiquitination in epithelial sodium channel degradation in untransfected renal A6 cells expressing endogenous ENaC subunits.Q40446280
Distinct pools of epithelial sodium channels are expressed at the plasma membraneQ40507820
Aquaporin gene expression and regulation in the ovine fetal lungQ40579815
Glucocorticoid-stimulated lung epithelial Na(+) transport is associated with regulated ENaC and sgk1 expressionQ40746673
Non-coordinate regulation of endogenous epithelial sodium channel (ENaC) subunit expression at the apical membrane of A6 cells in response to various transporting conditionsQ40856181
Glucocorticoid induction of epithelial sodium channel expression in lung and renal epithelia occurs via trans-activation of a hormone response element in the 5'-flanking region of the human epithelial sodium channel alpha subunit geneQ40959289
Regional expression of CFTR in developing human respiratory tissuesQ41038968
Number of subunits comprising the epithelial sodium channelQ41689667
Immunocytochemical and immunoelectron microscopic localization of alpha-, beta-, and gamma-ENaC in rat kidneyQ43607662
The gamma-subunit of ENaC is more important for channel surface expression than the beta-subunitQ44279076
Pharmacology and physiology of ovine corticosteroid receptorsQ44354104
Mineralocorticoid receptor expression in late-gestation ovine fetal lungQ45253535
Temporal regulation of CFTR expression during ovine lung development: implications for CF gene therapyQ45882885
Oxygen and glucocorticoids modulate alphaENaC mRNA translation in fetal distal lung epitheliumQ46740257
Glucocorticoid regulation of epithelial sodium channel genes in human fetal lungQ48047681
Early death due to defective neonatal lung liquid clearance in alpha-ENaC-deficient miceQ49019201
Lung epithelial Na channel subunits are differentially regulated during development and by steroids.Q52206392
Sensitivity of cortisol-induced inhibition of ACTH and renin in fetal sheepQ70139378
A morphologic and morphometric analysis of fetal lung development in the sheepQ71104260
Ontogeny of 11 beta-hydroxysteroid dehydrogenase in ovine fetal kidney and lungQ71632468
Epithelial Na(+) channel (ENaC) expression in the developing normal and abnormal human perinatal lungQ73675067
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectcortisolQ190875
P304page(s)R453-61
P577publication date2009-06-10
P1433published inAmerican Journal of Physiology - Regulatory, Integrative and Comparative PhysiologyQ2201819
P1476titleExpression of ENaC subunits, chloride channels, and aquaporins in ovine fetal lung: ontogeny of expression and effects of altered fetal cortisol concentrations
P478volume297

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cites work (P2860)
Q35095101A role for mineralocorticoid receptors in the physiology of the ovine fetus: effects on ACTH and lung liquid composition
Q47816769Differential effects of late gestation maternal overnutrition on the regulation of surfactant maturation in fetal and postnatal life
Q47736599Factors relating caesarean section to persistent pulmonary hypertension of the newborn
Q50422408Lack of cystic fibrosis transmembrane conductance regulator disrupts fetal airway development in pigs.
Q47945482Maternal chronic hypoxia increases expression of genes regulating lung liquid movement and surfactant maturation in male fetuses in late gestation.
Q34297457Mineralocorticoid effects in the late gestation ovine fetal lung
Q37411044The fetal sheep lung does not respond to cortisol infusion during the late canalicular phase of development
Q51116795The interaction of glucocorticoids and progesterone distinctively affects epithelial sodium transport.

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