The anti-tumor effect and increased tregs infiltration mediated by rAAV-SLC vector

scientific article published on October 2013

The anti-tumor effect and increased tregs infiltration mediated by rAAV-SLC vector is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S11033-013-2663-7
P932PMC publication ID3824217
P698PubMed publication ID24078089
P5875ResearchGate publication ID257206225

P2093author name stringLong Chen
Yinkun Liu
Binbin Zhou
Heng Hu
Huiying Ma
Chunmin Liang
Rilun Li
P2860cites workSecondary lymphoid-tissue chemokine is a functional ligand for the CC chemokine receptor CCR7Q24318384
Molecular cloning of a novel human CC chemokine secondary lymphoid-tissue chemokine that is a potent chemoattractant for lymphocytes and mapped to chromosome 9p13Q24319684
A chemokine expressed in lymphoid high endothelial venules promotes the adhesion and chemotaxis of naive T lymphocytesQ24681916
6-C-kine (SLC), a lymphocyte adhesion-triggering chemokine expressed by high endothelium, is an agonist for the MIP-3beta receptor CCR7Q24683114
SLC/CCL21-mediated anti-tumor responses require IFNgamma, MIG/CXCL9 and IP-10/CXCL10Q24797335
Control of regulatory T cell development by the transcription factor Foxp3Q27860489
Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseasesQ28131652
Role for CCR7 ligands in the emigration of newly generated T lymphocytes from the neonatal thymusQ28204211
CCR7-mediated physiological lymphocyte homing involves activation of a tyrosine kinase pathwayQ28209767
Roles of SLC/CCL21 and CCR7 in human kidney for mesangial proliferation, migration, apoptosis, and tissue homeostasisQ28215582
Isolation and characterization of Exodus-2, a novel C-C chemokine with a unique 37-amino acid carboxyl-terminal extensionQ28249290
Secondary lymphoid organ chemokine reduces pulmonary tumor burden in spontaneous murine bronchoalveolar cell carcinomaQ28584799
CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organsQ28594485
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Specific and nonspecific immunity in the prevention of spontaneous tumoursQ33702133
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Gene delivery to skeletal muscle results in sustained expression and systemic delivery of a therapeutic proteinQ35943644
The CC chemokine 6Ckine binds the CXC chemokine receptor CXCR3Q36172008
Mice lacking expression of the chemokines CCL21-ser and CCL19 (plt mice) demonstrate delayed but enhanced T cell immune responsesQ36369047
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Combined chemokine and cytokine gene transfer enhances antitumor immunityQ71607043
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The CC chemokine receptor-7 ligands 6Ckine and macrophage inflammatory protein-3 beta are potent chemoattractants for in vitro- and in vivo-derived dendritic cellsQ77320320
A ligand for the chemokine receptor CCR7 can influence the homeostatic proliferation of CD4 T cells and progression of autoimmunityQ77337846
CCR7 ligands, SLC/6Ckine/Exodus2/TCA4 and CKbeta-11/MIP-3beta/ELC, are chemoattractants for CD56(+)CD16(-) NK cells and late stage lymphoid progenitorsQ77380589
Secondary lymphoid-tissue chemokine (SLC) is chemotactic for mature dendritic cellsQ77785419
The lymphoid chemokine CCL21 costimulates naive T cell expansion and Th1 polarization of non-regulatory CD4+ T cellsQ81789751
CCR7 is critically important for migration of dendritic cells in intestinal lamina propria to mesenteric lymph nodesQ82176277
Certified professionals: CD4(+)CD25(+) suppressor T cellsQ36369181
CD4+ CD25+ regulatory T cells control T helper cell type 1 responses to foreign antigens induced by mature dendritic cells in vivoQ36371316
Antigenic cancer cells grow progressively in immune hosts without evidence for T cell exhaustion or systemic anergyQ36380365
Immune surveillance against a solid tumor fails because of immunological ignoranceQ37178041
Adeno-associated viral vector delivers cardiac-specific and hypoxia-inducible VEGF expression in ischemic mouse heartsQ37610441
Regulatory T cells prevent CD8 T cell maturation by inhibiting CD4 Th cells at tumor sites.Q40073121
Enhancement of immunity by a DNA melanoma vaccine against TRP2 with CCL21 as an adjuvant.Q40383031
Intratumoral administration of dendritic cells overexpressing CCL21 generates systemic antitumor responses and confers tumor immunity.Q40564039
Synergistic antitumor effect by coexpression of chemokine CCL21/SLC and costimulatory molecule LIGHT.Q40582098
Long-term expression of angiostatin suppresses metastatic liver cancer in miceQ40585480
Antitumor effects of the mouse chemokine 6Ckine/SLC through angiostatic and immunological mechanismsQ40864365
RANTES secretion by gene-modified tumor cells results in loss of tumorigenicity in vivo: role of immune cell subpopulationsQ41174063
Secondary lymphoid tissue chemokine mediates T cell-dependent antitumor responses in vivoQ41732041
Mice lacking expression of secondary lymphoid organ chemokine have defects in lymphocyte homing and dendritic cell localizationQ42064511
Long-term gene expression and phenotypic correction using adeno-associated virus vectors in the mammalian brainQ42280576
Herpes simplex virus (HSV) amplicon-mediated codelivery of secondary lymphoid tissue chemokine and CD40L results in augmented antitumor activityQ43416597
T cell-dependent antitumor immunity mediated by secondary lymphoid tissue chemokine: augmentation of dendritic cell-based immunotherapy.Q43561148
Combined HSV-TK/GCV and secondary lymphoid tissue chemokine gene therapy inhibits tumor growth and elicits potent antitumor CTL response in tumor-bearing miceQ43996182
Remission in models of type 1 diabetes by gene therapy using a single-chain insulin analogueQ45872828
Long-term modifications of blood pressure in normotensive and spontaneously hypertensive rats by gene delivery of rAAV-mediated cytochrome P450 arachidonic acid hydroxylaseQ45887484
In vivo expression of therapeutic human genes for dopamine production in the caudates of MPTP-treated monkeys using an AAV vectorQ45889326
Secondary lymphoid-tissue chemokine (SLC) stimulates integrin alpha 4 beta 7-mediated adhesion of lymphocytes to mucosal addressin cell adhesion molecule-1 (MAdCAM-1) under flow.Q46224027
Intrapulmonary administration of CCL21 gene-modified dendritic cells reduces tumor burden in spontaneous murine bronchoalveolar cell carcinomaQ46356356
The chemokine SLC is expressed in T cell areas of lymph nodes and mucosal lymphoid tissues and attracts activated T cells via CCR7.Q47915773
A lymphocyte-specific CC chemokine, secondary lymphoid tissue chemokine (SLC), is a highly efficient chemoattractant for B cells and activated T cellsQ48035864
P275copyright licenseCreative Commons Attribution 2.0 GenericQ19125117
P6216copyright statuscopyrightedQ50423863
P433issue10
P304page(s)5615-5623
P577publication date2013-10-01
P1433published inMolecular Biology ReportsQ15752755
P1476titleThe anti-tumor effect and increased tregs infiltration mediated by rAAV-SLC vector
P478volume40

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cites work (P2860)
Q27026177Adeno-associated virus-mediated cancer gene therapy: current status
Q30744724Subtumoral analysis of PRINT nanoparticle distribution reveals targeting variation based on cellular and particle properties

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