Combination of active specific immunotherapy or adoptive antibody or lymphocyte immunotherapy with chemotherapy in the treatment of cancer

scientific article published on 17 October 2008

Combination of active specific immunotherapy or adoptive antibody or lymphocyte immunotherapy with chemotherapy in the treatment of cancer is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1007/S00262-008-0598-Y
P932PMC publication ID2762732
P698PubMed publication ID18925393
P5875ResearchGate publication ID23388934

P50authorDorothee HerlynQ119728705
P2093author name stringTianqian Zhang
P2860cites workAdoptive cell transfer therapy following non-myeloablative but lymphodepleting chemotherapy for the treatment of patients with refractory metastatic melanomaQ24548019
Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytesQ24676216
A randomized phase II study of concurrent docetaxel plus vaccine versus vaccine alone in metastatic androgen-independent prostate cancerQ24684241
Doxorubicin and paclitaxel enhance the antitumor efficacy of vaccines directed against HER 2/neu in a murine mammary carcinoma modelQ24805875
Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2.Q27824766
Randomized phase II trial of the efficacy and safety of trastuzumab combined with docetaxel in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer administered as first-line treatment: the M77001 study groupQ27824835
Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancerQ27824847
Efficacy and safety of gemtuzumab ozogamicin in patients with CD33-positive acute myeloid leukemia in first relapseQ28204295
Calreticulin exposure dictates the immunogenicity of cancer cell deathQ28280438
Inhibitory effects of combinations of HER-2/neu antibody and chemotherapeutic agents used for treatment of human breast cancersQ28375856
Epidermal growth factor receptor blockade with C225 plus gemcitabine results in regression of human pancreatic carcinoma growing orthotopically in nude mice by antiangiogenic mechanismsQ73803447
Epidermal growth factor receptor-targeted therapy with C225 and cisplatin in patients with head and neck cancerQ73877537
In vivo depletion of B cells using a combination of high-dose cytosine arabinoside/mitoxantrone and rituximab for autografting in patients with non-Hodgkin's lymphomaQ74121696
Pilot trial of trastuzumab starting with or after the doxorubicin component of a doxorubicin plus paclitaxel regimen for women with HER2-positive advanced breast cancerQ79367332
Combination of chemotherapy and immunotherapy for cancer: a paradigm revisitedQ79464087
Necrotic tumor cell death in vivo impairs tumor-specific immune responsesQ79609715
Cancer immunotherapyQ80066933
Disseminated intravascular B-cell lymphoma: clinicopathological features and outcome of three cases treated with anthracycline-based immunochemotherapyQ80209418
Immunological evaluation of personalized peptide vaccination in combination with a 5-fluorouracil derivative (TS-1) for advanced gastric or colorectal carcinoma patientsQ80216646
Combination of transient lymphodepletion with busulfan and fludarabine and peptide vaccination in a phase I clinical trial for patients with advanced melanomaQ80243204
Potent and specific antitumor efficacy of CMC-544, a CD22-targeted immunoconjugate of calicheamicin, against systemically disseminated B-cell lymphomaQ81208645
Immunotherapy and chemotherapy--a practical partnershipQ81703535
Synergistic effects of combined therapy using paclitaxel and [90Y-DOTA]776.1 on growth of OVCAR-3 ovarian carcinoma xenograftsQ82359485
Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancerQ29616112
Phase II study of rituximab in combination with chop chemotherapy in patients with previously untreated, aggressive non-Hodgkin's lymphomaQ32034092
Trastuzumab in combination with metronomic cyclophosphamide and methotrexate in patients with HER-2 positive metastatic breast cancerQ33257718
A phase I study of nonmyeloablative chemotherapy and adoptive transfer of autologous tumor antigen-specific T lymphocytes in patients with metastatic melanomaQ33342339
Antibody-targeted chemotherapy of older patients with acute myeloid leukemia in first relapse using Mylotarg (gemtuzumab ozogamicin).Q33343994
Cetuximab, a monoclonal antibody targeting the epidermal growth factor receptor, in combination with gemcitabine for advanced pancreatic cancer: a multicenter phase II TrialQ33361488
Immunological evaluation of personalized peptide vaccination with gemcitabine for pancreatic cancerQ33374300
Synergistic anti-tumor effect of recombinant chicken fibroblast growth factor receptor-1-mediated anti-angiogenesis and low-dose gemcitabine in a mouse colon adenocarcinoma modelQ34098565
Photodynamic therapy and anti-tumour immunity.Q34105703
Antibody-targeted chemotherapy with CMC-544: a CD22-targeted immunoconjugate of calicheamicin for the treatment of B-lymphoid malignanciesQ34276476
Biological treatment in acute myelogenous leukaemia: how should T-cell targeting immunotherapy be combined with intensive chemotherapy?Q34452706
Phase I studies of anti-epidermal growth factor receptor chimeric antibody C225 alone and in combination with cisplatin.Q34507119
Enhanced antitumor activity of anti-epidermal growth factor receptor monoclonal antibody IMC-C225 in combination with irinotecan (CPT-11) against human colorectal tumor xenograftsQ34523090
Chemo-immunotherapy and chemo-adoptive immunotherapy of cancerQ34574205
Immunochemotherapy in indolent non-Hodgkin's lymphomaQ34662952
Rituximab in combination with CHOP improves survival in elderly patients with aggressive non-Hodgkin's lymphomaQ34662961
The combination of chemotherapy and systemic immunotherapy and the concept of cure in murine leukemia and lymphomaQ35047632
Immunotherapy: new options in breast cancer treatmentQ35160235
Immunotherapy as part of combinations for the treatment of cancerQ35177544
Immunomodulation in cancer therapeuticsQ35177553
Combinations of anticancer drugs and immunotherapyQ35207136
Epigallocatechin-3-gallate enhances CD8+ T cell-mediated antitumor immunity induced by DNA vaccination.Q35234948
Increased intensity lymphodepletion and adoptive immunotherapy--how far can we go?Q35594089
Immunotherapy of malignant diseases. Challenges and strategies.Q35621079
Anticancer therapeutic potential of soy isoflavone, genistein.Q35975993
Breast cancer vaccines: maximizing cancer treatment by tapping into host immunityQ36078972
Monoclonal antibody Po66 uptake by human lung tumours implanted in nude mice: effect of co-administration with doxorubicinQ36081335
Synergy of Taxol and radioimmunotherapy with yttrium-90-labeled chimeric L6 antibody: efficacy and toxicity in breast cancer xenograftsQ36108564
Active specific immunotherapy in colon cancerQ36112295
Continuing challenges in childhood non-Hodgkin's lymphomaQ36228057
Induced sensitization of tumor stroma leads to eradication of established cancer by T cellsQ36228950
Perspectives of immunotherapy in metastatic breast cancer.Q36333747
Cranking the immunologic engine with chemotherapy: using context to drive tumor antigen cross-presentation towards useful antitumor immunity.Q36372880
Caspase-dependent immunogenicity of doxorubicin-induced tumor cell deathQ36403093
Therapeutic lymphoma vaccines: importance of T-cell immunityQ36530231
Combined radioimmunotherapy and chemotherapy of human colon carcinoma grafted in nude mice, advantages and limitationsQ44664828
Immunological evaluation of individualized peptide vaccination with a low dose of estramustine for HLA-A24+ HRPC patientsQ45066205
Inhibition of CD4(+)25+ T regulatory cell function implicated in enhanced immune response by low-dose cyclophosphamideQ45182740
Complete regression of large solid tumors using engineered drug-resistant hematopoietic cells and anti-CD137 immunotherapyQ45862115
Drug-mediated immunogenic changes of virus-induced leukemia in vivoQ45881963
Remission of human breast cancer xenografts on therapy with humanized monoclonal antibody to HER-2 receptor and DNA-reactive drugsQ46227342
Antibody to HER-2/neu receptor blocks DNA repair after cisplatin in human breast and ovarian cancer cells.Q46246951
Combination of low-dose gemcitabine and recombinant quail vascular endothelial growth factor receptor-2 as a vaccine induces synergistic antitumor activitiesQ46641344
Phase II study of receptor-enhanced chemosensitivity using recombinant humanized anti-p185HER2/neu monoclonal antibody plus cisplatin in patients with HER2/neu-overexpressing metastatic breast cancer refractory to chemotherapy treatmentQ46641346
5-fluorouracil-based chemotherapy enhances the antitumor activity of a thymidylate synthase-directed polyepitopic peptide vaccine.Q46735710
Clinical responsiveness of glioblastoma multiforme to chemotherapy after vaccinationQ46859959
Chemoimmunotherapeutic approach to prolonged survival time in combination with immunization and glutamic Acid derivatives with antitumor activity in tumor-bearing mice.Q46867617
Recombinant humanized anti-HER2 antibody (Herceptin) enhances the antitumor activity of paclitaxel and doxorubicin against HER2/neu overexpressing human breast cancer xenograftsQ47854934
Cross-priming by temozolomide enhances antitumor immunity of dendritic cell vaccination in murine brain tumor modelQ48287471
Antitumor immune response induced by i.t. injection of vector-activated dendritic cells and chemotherapy suppresses metastatic breast cancer.Q50718079
2-year follow-up of trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer: a randomised controlled trial.Q53243856
Phase II trial of CHOP chemotherapy followed by tositumomab/iodine I-131 tositumomab for previously untreated follicular non-Hodgkin's lymphoma: five-year follow-up of Southwest Oncology Group Protocol S9911.Q53251676
Vaccination of colorectal cancer patients with modified vaccinia ankara encoding the tumor antigen 5T4 (TroVax) given alongside chemotherapy induces potent immune responses.Q53470311
A chitosan hydrogel-based cancer drug delivery system exhibits synergistic antitumor effects by combining with a vaccinia viral vaccine.Q53561395
Role of antitumor immunity in cyclophosphamide-induced rejection of subcutaneous nonpalpable MOPC-315 tumors.Q54520670
Combined effects of chemotherapy and immunity against leukemia L1210 in DBA-2 mice.Q54591297
Enhanced antitumour immunity by combined use of temozolomide and TAT-survivin pulsed dendritic cells in a murine glioma.Q55467906
Phase II Multicenter Study of the Antiepidermal Growth Factor Receptor Monoclonal Antibody Cetuximab in Combination With Platinum-Based Chemotherapy in Patients With Platinum-Refractory Metastatic and/or Recurrent Squamous Cell Carcinoma of the HeadQ56688854
Antitumor Activity of Combined Blockade of Epidermal Growth Factor Receptor and Protein Kinase AQ57424743
Antigenic changes related to drug actionQ58855462
In vitro generation of primary cytotoxic lymphocytes against L5178Y leukemia antigenically altered by 5-(3,3'-dimethyl-1-triazeno)-imidazole-4-carboxamide in vivoQ58855473
Single administration of low dose cyclophosphamide augments the antitumor effect of dendritic cell vaccineQ61788033
Cutting edge: differential effect of apoptotic versus necrotic tumor cells on macrophage antitumor activitiesQ63197865
Combination of p53 cancer vaccine with chemotherapy in patients with extensive stage small cell lung cancerQ64378051
Antigenic Changes of L5178Y Lymphoma After Treatment With 5-(3,3-Dimethyl-1-triazeno)imidazole-4-carboxamide In Vivo 2Q67440168
Correlations between humoral immunity and successful chemotherapy-immunotherapyQ67493233
Chemotherapy versus chemotherapy with intralymphatic tumor cell vaccine in canine lymphomaQ68322594
Treatment of advanced measurable or evaluable pancreatic carcinoma with 17-1A murine monoclonal antibody alone or in combination with 5-fluorouracil, adriamycin and mitomycin (FAM)Q68895286
Experience with the use of high-dose interleukin-2 in the treatment of 652 cancer patientsQ69548004
Effect of low dose cyclophosphamide on the immune system of cancer patients: depletion of CD4+, 2H4+ suppressor-inducer T-cellsQ69820065
Evaluation of lymphocyte immunity in breast cancer patientsQ70483069
Antitumor effect of anti-epidermal growth factor receptor monoclonal antibodies plus cis-diamminedichloroplatinum on well established A431 cell xenograftsQ70487549
Modification of tumor regression by immunologic meansQ71338053
Some advantages of curing mice bearing a large subcutaneous MOPC-315 tumor with a low dose rather than a high dose of cyclophosphamideQ71733345
Treatment of patients with metastatic melanoma with autologous tumor-infiltrating lymphocytes and interleukin 2Q72052802
Antitumor effects of doxorubicin in combination with anti-epidermal growth factor receptor monoclonal antibodiesQ72856071
Treatment of human lung carcinoma xenografts with a combination of 131I-labelled monoclonal antibody Po66 and doxorubicinQ73048337
Response of prostate cancer to anti-Her-2/neu antibody in androgen-dependent and -independent human xenograft modelsQ73078396
A phase I/II trial of iodine-131-tositumomab (anti-CD20), etoposide, cyclophosphamide, and autologous stem cell transplantation for relapsed B-cell lymphomasQ73119226
CHOP plus rituximab chemoimmunotherapy of indolent B-cell lymphomaQ73181016
CD8+ T cells activated during the course of murine acute myelogenous leukemia elicit therapeutic responses to late B7 vaccines after cytoreductive treatmentQ73235541
Enhanced antitumor activity of combination radioimmunotherapy (131I-labeled monoclonal antibody A33) with chemotherapy (fluorouracil)Q73424522
Addition of cisplatin improves efficacy of 131I-labeled monoclonal antibody 323/A3 in experimental human ovarian cancerQ73516937
Clearance of apoptotic and necrotic cells and its immunological consequencesQ36585103
Evidence accumulating in support of cancer vaccines combined with chemotherapy: a pragmatic review of past and present efforts.Q36590513
Phase I study of the humanised anti-EGFR monoclonal antibody matuzumab (EMD 72000) combined with gemcitabine in advanced pancreatic cancerQ36614598
Current status of immunotherapy in B cell malignanciesQ36638492
Role of immunochemotherapy in the treatment of chronic lymphocytic leukemiaQ36689156
Links between innate and cognate tumor immunityQ36736618
Future strategies for targeted therapies and tailored patient management in pancreatic cancerQ36901260
Immunotherapy for prostate cancer - recent progress in clinical trials.Q36902793
Ecto-calreticulin in immunogenic chemotherapyQ36990570
Immunological aspects of cancer chemotherapyQ37039588
Cancer treatment: the combination of vaccination with other therapiesQ37089001
Cancer chemotherapy: not only a direct cytotoxic effect, but also an adjuvant for antitumor immunityQ37120261
Cancer regression in patients with metastatic melanoma after the transfer of autologous antitumor lymphocytesQ37570109
Enhanced efficacy in anti-tumour activity by combined therapy of recombinant FGFR-1 related angiogenesis and low-dose cytotoxic agentQ39629473
Preclinical evaluation of the interrelationships between cancer chemotherapy and immunityQ39907004
Chemotherapeutic drugs may be used to enhance the killing efficacy of human tumor antigen peptide-specific CTLsQ39982106
Effect of frequently used chemotherapeutic drugs on cytotoxic activity of human cytotoxic T-lymphocytes.Q40006148
A combination of chemoimmunotherapies can efficiently break self-tolerance and induce antitumor immunity in a tolerogenic murine tumor modelQ40099109
Therapeutic potential of CD22-specific antibody-targeted chemotherapy using inotuzumab ozogamicin (CMC-544) for the treatment of acute lymphoblastic leukemiaQ40101776
Chemotherapy enhances CD8(+) T cell-mediated antitumor immunity induced by vaccination with vaccinia virusQ40123387
Different mechanisms for anti-tumor effects of low- and high-dose cyclophosphamide.Q40265244
Antitumor efficacy of a combination of CMC-544 (inotuzumab ozogamicin), a CD22-targeted cytotoxic immunoconjugate of calicheamicin, and rituximab against non-Hodgkin's B-cell lymphomaQ40333268
In vivo and in vitro antitumor activity of oxaliplatin in combination with cetuximab in human colorectal tumor cell lines expressing different level of EGFR.Q40345495
Antibody-targeted chemotherapy of B-cell lymphoma using calicheamicin conjugated to murine or humanized antibody against CD22.Q40461812
Combination of low-dose cisplatin and recombinant xenogeneic endoglin as a vaccine induces synergistic antitumor activities.Q40481100
Treatment of melanoma with 5-fluorouracil or dacarbazine in vitro sensitizes cells to antigen-specific CTL lysis through perforin/granzyme- and Fas-mediated pathwaysQ40575783
Low-dose radioimmunotherapy ((90)Y-PAM4) combined with gemcitabine for the treatment of experimental pancreatic cancerQ40632020
Treatment of patients with low-grade B-cell lymphoma with the combination of chimeric anti-CD20 monoclonal antibody and CHOP chemotherapyQ40634072
Selective ablation of acute myeloid leukemia using antibody-targeted chemotherapy: a phase I study of an anti-CD33 calicheamicin immunoconjugateQ40638371
Antitumor activity of sequential treatment with topotecan and anti-epidermal growth factor receptor monoclonal antibody C225.Q40959114
Changes of the immunogenic properties of a radiation-induced mouse lymphoma following treatment with antitumor drugsQ41069939
B7-1-transfected tumor vaccine counteracts chemotherapy-induced immunosuppression and prolongs the survival of rats bearing highly metastatic osteosarcoma cellsQ41105180
Chimeric anti-CD20 (IDEC-C2B8) monoclonal antibody sensitizes a B cell lymphoma cell line to cell killing by cytotoxic drugsQ41105815
Drug-induced immunogenic changes of murine leukemia cells: dissociation of onset of resistance and emergence of novel immunogenicity.Q41584252
Drug-mediated antigenic changes in murine leukemia cells: antagonistic effects of quinacrine, an antimutagenic compoundQ41610482
A monoclonal antibody against the c-erbB-2 protein enhances the cytotoxicity of cis-diamminedichloroplatinum against human breast and ovarian tumor cell linesQ41668009
Combination therapy with trastuzumab (Herceptin) and cisplatin for chemoresistant metastatic breast cancer: evidence for receptor-enhanced chemosensitivityQ41689760
Vaccination of colorectal cancer patients with TroVax given alongside chemotherapy (5-fluorouracil, leukovorin and irinotecan) is safe and induces potent immune responsesQ42638914
Cyclophosphamide, doxorubicin, and paclitaxel enhance the antitumor immune response of granulocyte/macrophage-colony stimulating factor-secreting whole-cell vaccines in HER-2/neu tolerized mice.Q42829424
Rexpression of HLA class I antigens and restoration of antigen-specific CTL response in melanoma cells following 5-aza-2'-deoxycytidine treatmentQ43773475
Comparative analysis of necrotic and apoptotic tumor cells as a source of antigen(s) in dendritic cell-based immunization.Q43806539
CHOP chemotherapy plus rituximab compared with CHOP alone in elderly patients with diffuse large-B-cell lymphomaQ43864036
Hepatic sinusoidal obstruction after gemtuzumab ozogamicin (Mylotarg) therapyQ43918508
High-dose chemo-radioimmunotherapy with autologous stem cell support for relapsed mantle cell lymphomaQ43966195
Low doses of chemotherapy to inhibit suppressor T cells.Q44116665
Induction of tumor cell apoptosis in vivo increases tumor antigen cross-presentation, cross-priming rather than cross-tolerizing host tumor-specific CD8 T cellsQ44432115
A phase 2 trial of CHOP chemotherapy followed by tositumomab/iodine I 131 tositumomab for previously untreated follicular non-Hodgkin lymphoma: Southwest Oncology Group Protocol S9911Q44435109
Synergy between chemotherapy and immunotherapy in the treatment of established murine solid tumorsQ44542342
P433issue4
P921main subjectantibodyQ79460
immunotherapyQ1427096
lymphocyteQ715347
chemotherapyQ974135
P304page(s)475-492
P577publication date2008-10-17
P1433published inCancer Immunology, ImmunotherapyQ5031409
P1476titleCombination of active specific immunotherapy or adoptive antibody or lymphocyte immunotherapy with chemotherapy in the treatment of cancer
P478volume58

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cites work (P2860)
Q37416204Antitumor effects of anti-CD40/CpG immunotherapy combined with gemcitabine or 5-fluorouracil chemotherapy in the B16 melanoma model
Q43165459Application of nanoparticles on diagnosis and therapy in gliomas.
Q53870991Chemotherapeutic agents in low noncytotoxic concentrations increase immunogenicity of human colon cancer cells.
Q37892600Colorectal cancer vaccines in clinical trials.
Q48283444Comparison of circadian characteristics for cytotoxic lymphocyte subsets in non-small cell lung cancer patients versus controls
Q41115927Cytotoxic T lymphocytes promote cytarabine-induced acute myeloid leukemia cell apoptosis via inhibiting Bcl-2 expression
Q38202569Epidemiology of infections in cancer patients
Q35564075Gene Expression Profiling and Pathway Network Analysis Predicts a Novel Antitumor Function for a Botanical-Derived Drug, PG2
Q39409268Highly potent mRNA based cancer vaccines represent an attractive platform for combination therapies supporting an improved therapeutic effect
Q39144327Immune-Mediated Therapies for Liver Cancer.
Q37891875Immunotherapy of prostate cancer: should we be targeting stem cells and EMT?
Q39616709Mechanisms of T-cell protection from death by IRX-2: a new immunotherapeutic.
Q35837949Optimizing molecular-targeted therapies in ovarian cancer: the renewed surge of interest in ovarian cancer biomarkers and cell signaling pathways
Q33823499Paclitaxel enhances early dendritic cell maturation and function through TLR4 signaling in mice
Q36579336Prospective of colon cancer treatments and scope for combinatorial approach to enhanced cancer cell apoptosis
Q39566639The gene expression profile of unstimulated dendritic cells can be used as a predictor of function.
Q39646317The use of layered double hydroxides as DNA vaccine delivery vector for enhancement of anti-melanoma immune response
Q37765590Unravelling the complexity of cancer-immune system interplay
Q33781142What's the place of immunotherapy in malignant mesothelioma treatments?

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