Factor Xa activation of factor V is of paramount importance in initiating the coagulation system: lessons from a tick salivary protein

scientific article published on July 2013

Factor Xa activation of factor V is of paramount importance in initiating the coagulation system: lessons from a tick salivary protein is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1161/CIRCULATIONAHA.113.003191
P932PMC publication ID3826089
P698PubMed publication ID23817575
P5875ResearchGate publication ID244481605

P50authorGerry A F NicolaesQ87766074
Erol FikrigQ28355961
Sirlei DaffreQ47815368
Tom van der PollQ63136192
P2093author name stringTim J Schuijt
Joost C M Meijers
Kamran Bakhtiari
Cornelis van 't Veer
Rodney M Camire
Simone J H Wielders
Matthew W Bunce
Joppe W Hovius
Kathleen Deponte
J Arnoud Marquart
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The contribution of bovine Factor V and Factor Va to the activity of prothrombinaseQ28249212
The role of phospholipids and factor Va in the prothrombinase complexQ28281889
Cofactor proteins in the assembly and expression of blood clotting enzyme complexesQ28289123
The initiation phase--a review of old (clotting-) timesQ80541033
NOTE ON THE ADSORPTION OF THROMBIN ON FIBRINQ81007721
Phylogeny of hard- and soft-tick taxa (Acari: Ixodida) based on mitochondrial 16S rDNA sequencesQ28775933
Salivating for knowledge: potential pharmacological agents in tick salivaQ33319614
Identification and characterization of Ixodes scapularis antigens that elicit tick immunity using yeast surface displayQ33796652
Factor V and thrombotic disease: description of a janus-faced proteinQ34123469
AN ENZYME CASCADE IN THE BLOOD CLOTTING MECHANISM, AND ITS FUNCTION AS A BIOCHEMICAL AMPLIFIER.Q34257237
WATERFALL SEQUENCE FOR INTRINSIC BLOOD CLOTTING.Q34257361
Mutation in blood coagulation factor V associated with resistance to activated protein C.Q34340007
The molecular basis of factor V and VIII procofactor activationQ34358555
Protein S stimulates inhibition of the tissue factor pathway by tissue factor pathway inhibitorQ34479961
Factor XI activation in a revised model of blood coagulationQ34500136
A tick mannose-binding lectin inhibitor interferes with the vertebrate complement cascade to enhance transmission of the lyme disease agentQ35207953
Disruption of Ixodes scapularis anticoagulation by using RNA interferenceQ36016860
A bipartite autoinhibitory region within the B-domain suppresses function in factor VQ36122255
The role of thrombin exosites I and II in the activation of human coagulation factor V.Q36538501
Tick anti-hemostatics: targets for future vaccines and therapeuticsQ36893118
The pleiotropic role of the fibrinogen gamma' chain in hemostasisQ37581345
Lyme borreliosis vaccination: the facts, the challenge, the futureQ37769326
The molecular structure of fibrinogenQ39868072
Nematode anticoagulant protein c2 reveals a site on factor Xa that is important for macromolecular substrate binding to human prothrombinaseQ40732079
Factor Xa is highly protected from antithrombin-fondaparinux and antithrombin-enoxaparin when incorporated into the prothrombinase complexQ44518771
Recombinant factor VIIa reverses the anticoagulant effect of the long-acting pentasaccharide idraparinux in healthy volunteersQ44761447
Activation of human factor V by meizothrombin.Q47855618
The factor V activation paradoxQ50335791
A model for the stoichiometric regulation of blood coagulation.Q52044713
Factor VIIa/tissue factor generates a form of factor V with unchanged specific activity, resistance to activation by thrombin, and increased sensitivity to activated protein C.Q54104793
Activation of human factor V by factor Xa and thrombinQ68747564
A model for the tissue factor pathway to thrombin. I. An empirical studyQ72181568
Regulation of tissue factor initiated thrombin generation by the stoichiometric inhibitors tissue factor pathway inhibitor, antithrombin-III, and heparin cofactor-IIQ73039117
Cleavage requirements for activation of factor V by factor XaQ73568234
Ultrasensitive fluorogenic substrates for serine proteasesQ73866804
Regions remote from the site of cleavage determine macromolecular substrate recognition by the prothrombinase complexQ74465618
Inhibition of thrombin generation in plasma by fibrin formation (Antithrombin I)Q74658343
Regulation of prothrombinase activity by protein SQ78155532
P4510describes a project that usesImageJQ1659584
P433issue3
P407language of work or nameEnglishQ1860
P304page(s)254-266
P577publication date2013-07-01
P1433published inCirculationQ578091
P1476titleFactor Xa activation of factor V is of paramount importance in initiating the coagulation system: lessons from a tick salivary protein
P478volume128

Reverse relations

cites work (P2860)
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Q36250499Identification and anticoagulant activity of a novel Kunitz-type protein HA11 from the salivary gland of the tick Hyalomma asiaticum
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Q88234691Reduced Prothrombinase Inhibition by Tissue Factor Pathway Inhibitor Contributes to the Factor V Leiden Hypercoagulable State
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Q93052249Salp15, a Multifunctional Protein From Tick Saliva With Potential Pharmaceutical Effects
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