scholarly article | Q13442814 |
P356 | DOI | 10.3390/MD11103802 |
P8608 | Fatcat ID | release_yr6sp5kxivewpe2evqmbzhfj7i |
P932 | PMC publication ID | 3826136 |
P698 | PubMed publication ID | 24152558 |
P5875 | ResearchGate publication ID | 258038281 |
P50 | author | Kirsten Benkendorff | Q47159752 |
Martin R Johnston | Q56949145 | ||
Catherine Anne Abbott | Q39188539 | ||
P2093 | author name string | Babak Esmaeelian | |
P2860 | cites work | Global cancer statistics | Q22241238 |
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GSK-3-selective inhibitors derived from Tyrian purple indirubins | Q27642879 | ||
Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008 | Q27860674 | ||
Indirubin and indigo are potent aryl hydrocarbon receptor ligands present in human urine | Q28203680 | ||
Sulforaphane, a naturally occurring isothiocyanate, induces cell cycle arrest and apoptosis in HT29 human colon cancer cells | Q73574350 | ||
A natural peptide, dolastatin 15, induces G2/M cell cycle arrest and apoptosis of human multiple myeloma cells | Q80286682 | ||
Marine natural products | Q85775737 | ||
Sex-specific Tyrian purple genesis: precursor and pigment distribution in the reproductive system of the marine mollusc, Dicathais orbita. | Q46853794 | ||
Inhibition of heat shock protein 90 function by 17-allylamino-17-demethoxy-geldanamycin in Hodgkin's lymphoma cells down-regulates Akt kinase, dephosphorylates extracellular signal-regulated kinase, and induces cell cycle arrest and cell death | Q46905283 | ||
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Tyrian Purple: 6,6’-Dibromoindigo and Related Compounds | Q56138636 | ||
The endogenous oxindoles 5-hydroxyoxindole and isatin are antiproliferative and proapoptotic | Q73006132 | ||
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Innovative agents in cancer prevention. | Q30349981 | ||
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Molluscan biological and chemical diversity: secondary metabolites and medicinal resources produced by marine molluscs | Q33526826 | ||
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Caspase structure, proteolytic substrates, and function during apoptotic cell death | Q33782479 | ||
Use of multiple assay endpoints to investigate the effects of incubation time, dose of toxin, and plating density in cell-based cytotoxicity assays | Q34314238 | ||
Direct activation of the apoptosis machinery as a mechanism to target cancer cells | Q35145998 | ||
Marine compounds selectively induce apoptosis in female reproductive cancer cells but not in primary-derived human reproductive granulosa cells | Q35759919 | ||
Molecular mechanisms of indirubin and its derivatives: novel anticancer molecules with their origin in traditional Chinese phytomedicine | Q35876121 | ||
Marine natural products as anticancer drugs | Q36043234 | ||
Overview of cell death signaling pathways | Q36051647 | ||
Antitumor activity of new substituted 3-(5-imidazo[2,1-b]thiazolylmethylene)-2-indolinones and study of their effect on the cell cycle | Q36233471 | ||
A death-promoting role for extracellular signal-regulated kinase | Q36519679 | ||
Gastrointestinal and hepatotoxicity assessment of an anticancer extract from muricid molluscs | Q36838178 | ||
Natural product research in the Australian marine invertebrate Dicathais orbita | Q36994269 | ||
Natural products and colon cancer: current status and future prospects | Q37136990 | ||
Cytotoxic and anticancer activities of isatin and its derivatives: a comprehensive review from 2000-2008. | Q37481467 | ||
Importance of influx and efflux systems and xenobiotic metabolizing enzymes in intratumoral disposition of anticancer agents | Q37580931 | ||
A potent indole-3-carbinol derived antitumor agent with pleiotropic effects on multiple signaling pathways in prostate cancer cells. | Q40093765 | ||
In vitro cytotoxicity evaluation of some substituted isatin derivatives. | Q40211510 | ||
Indirubin enhances tumor necrosis factor-induced apoptosis through modulation of nuclear factor-kappa B signaling pathway. | Q40265640 | ||
Modification of MTT assay conditions to examine the cytotoxic effects of amitraz on the human lymphoblastoid cell line, WIL2NS. | Q40381015 | ||
A-432411, a novel indolinone compound that disrupts spindle pole formation and inhibits human cancer cell growth | Q40435914 | ||
A novel cdk2-selective inhibitor, SU9516, induces apoptosis in colon carcinoma cells | Q40785882 | ||
Anti-mitotic properties of indirubin-3'-monoxime, a CDK/GSK-3 inhibitor: induction of endoreplication following prophase arrest | Q40794493 | ||
Indirubin, the active constituent of a Chinese antileukaemia medicine, inhibits cyclin-dependent kinases | Q40918567 | ||
Bioactivity of the Murex Homeopathic Remedy and of Extracts from an Australian Muricid Mollusc against Human Cancer Cells | Q41951957 | ||
Enhanced acute apoptotic response to azoxymethane-induced DNA damage in the rodent colonic epithelium by Tyrian purple precursors: a potential colorectal cancer chemopreventative | Q43164583 | ||
Indirubins inhibit glycogen synthase kinase-3 beta and CDK5/p25, two protein kinases involved in abnormal tau phosphorylation in Alzheimer's disease. A property common to most cyclin-dependent kinase inhibitors? | Q43507724 | ||
Geraniol, a component of plant essential oils, sensitizes human colonic cancer cells to 5-Fluorouracil treatment | Q43964624 | ||
To arrest or not to G(2)-M Cell-cycle arrest : commentary re: A. K. Tyagi et al., Silibinin strongly synergizes human prostate carcinoma DU145 cells to doxorubicin-induced growth inhibition, G(2)-M arrest, and apoptosis. Clin. cancer res., 8: 3512-3 | Q44214945 | ||
Transient induction of cytochromes P450 1A1 and 1B1 in MCF-7 human breast cancer cells by indirubin | Q44668644 | ||
Sulforaphane-induced G2/M phase cell cycle arrest involves checkpoint kinase 2-mediated phosphorylation of cell division cycle 25C. | Q44836647 | ||
From the insoluble dye indirubin towards highly active, soluble CDK2-inhibitors | Q45293374 | ||
Disorders of folliculogenesis are associated with abnormal expression of peripheral benzodiazepine receptors in granulosa cells | Q46234766 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 10 | |
P921 | main subject | colorectal cancer | Q188874 |
Dicathais orbita | Q737213 | ||
apoptotic process | Q14599311 | ||
colorectal carcinoma | Q25493920 | ||
P304 | page(s) | 3802-3822 | |
P577 | publication date | 2013-10-11 | |
P1433 | published in | Marine Drugs | Q2122804 |
P1476 | title | Purified brominated indole derivatives from Dicathais orbita induce apoptosis and cell cycle arrest in colorectal cancer cell lines | |
P478 | volume | 11 |
Q37566156 | 6-bromoisatin found in muricid mollusc extracts inhibits colon cancer cell proliferation and induces apoptosis, preventing early stage tumor formation in a colorectal cancer rodent model. |
Q52881957 | Allyl-isatin suppresses cell viability, induces cell cycle arrest, and promotes cell apoptosis in hepatocellular carcinoma HepG2 cells. |
Q33744128 | Anti-Inflammatory Activity and Structure-Activity Relationships of Brominated Indoles from a Marine Mollusc. |
Q37566258 | Apoptogenic metabolites in fractions of the Benthic diatom Cocconeis scutellum parva. |
Q26795884 | Are the Traditional Medical Uses of Muricidae Molluscs Substantiated by Their Pharmacological Properties and Bioactive Compounds? |
Q28088279 | Biological Activity of Recently Discovered Halogenated Marine Natural Products |
Q47143811 | Brominated indoles from a marine mollusc inhibit inflammation in a murine model of acute lung injury |
Q64963419 | Bromoperoxidase Producing Bacillus spp. Isolated from the Hypobranchial Glands of a Muricid Mollusc Are Capable of Tyrian Purple Precursor Biogenesis. |
Q35816225 | Characterization of Bacterial Communities Associated with the Tyrian Purple Producing Gland in a Marine Gastropod. |
Q35649627 | Combined Effects of Muricid Extract and 5-Fluorouracil on Intestinal Toxicity in Rats. |
Q51084134 | Extraction and Quantification of Bioactive Tyrian Purple Precursors: A Comparative and Validation Study from the Hypobranchial Gland of a Muricid Dicathais orbita. |
Q64236328 | Induction of Apoptosis by Extract of Persian Gulf Marine Mollusk, through the ROS-Mediated Mitochondrial Targeting on Human Epithelial Ovarian Cancer Cells |
Q92882970 | Mapping insoluble indole metabolites in the gastrointestinal environment of a murine colorectal cancer model using desorption/ionisation on porous silicon imaging |
Q43239058 | Marine Compounds and Cancer: Where Do We Stand? |
Q33834080 | Marine Mollusk-Derived Agents with Antiproliferative Activity as Promising Anticancer Agents to Overcome Chemotherapy Resistance. |
Q38851937 | Simultaneous Assessment of the Efficacy and Toxicity of Marine Mollusc-Derived Brominated Indoles in an In Vivo Model for Early Stage Colon Cancer. |
Q35228238 | Solvent separating secondary metabolites directly from biosynthetic tissue for surface-assisted laser desorption ionisation mass spectrometry |
Q36083549 | Transcriptome of the Australian Mollusc Dicathais orbita Provides Insights into the Biosynthesis of Indoles and Choline Esters. |
Q90706223 | Upregulation of DLC-1 inhibits pancreatic cancer progression: Studies with clinical samples and a pancreatic cancer model |
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