Antiepileptic effects of silk-polymer based adenosine release in kindled rats.

scientific article published on 19 May 2009

Antiepileptic effects of silk-polymer based adenosine release in kindled rats. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.EXPNEUROL.2009.05.018
P932PMC publication ID2728789
P698PubMed publication ID19460372
P5875ResearchGate publication ID24444531

P50authorTheresa A. LusardiQ43161290
Detlev BoisonQ43161293
David L. KaplanQ61761312
P2093author name stringTianfu Li
Eleanor M Pritchard
Andrew Wilz
Cory Szybala
P2860cites workAdenosine receptors as therapeutic targetsQ24632095
Grafts of adenosine-releasing cells suppress seizures in kindling epilepsyQ28366761
Functionalized silk-based biomaterials for bone formation.Q31565805
Silk coatings on PLGA and alginate microspheres for protein deliveryQ33288412
Kindling: the first decadeQ33539958
Emerging insights into the genesis of epilepsyQ33678164
The role and regulation of adenosine in the central nervous systemQ34205330
Current status and future directions in the pharmacotherapy of epilepsyQ34552599
Cell and gene therapies in epilepsy--promising avenues or blind alleys?Q34737233
In vivo degradation of three-dimensional silk fibroin scaffoldsQ34781676
Silk-based biomaterialsQ34992589
The clinical potential of antiepileptic gene therapyQ35925614
Adenosine and brain functionQ36083482
Actions of adenosine at its receptors in the CNS: insights from knockouts and drugsQ36094581
Kinetic studies of rat liver adenosine kinase. Explanation of exchange reaction between adenosine and AMPQ72050247
Focal treatment for refractory epilepsy: hope for the future?Q79739749
Lentiviral RNAi-induced downregulation of adenosine kinase in human mesenchymal stem cell grafts: a novel perspective for seizure control.Q36391066
The adenosine kinase hypothesis of epileptogenesisQ36515651
Concise review: prospects of stem cell therapy for temporal lobe epilepsy.Q36729233
Adenosine-based cell therapy approaches for pharmacoresistant epilepsies.Q36788952
Silk polymer-based adenosine release: therapeutic potential for epilepsyQ36819103
Cell therapy in models for temporal lobe epilepsyQ36848783
Pharmacotherapy of epilepsy: new armamentarium, new issuesQ36873342
Adenosine dysfunction in astrogliosis: cause for seizure generation?Q36923994
Adenosine as a neuromodulator in neurological diseasesQ36974004
The promise of gene therapy for the treatment of epilepsyQ37021317
Adenosine as a modulator of brain activity.Q37095277
Cell and gene therapies for refractory epilepsy.Q37211817
Neuroprotection by adenosine in the brain: From A(1) receptor activation to A (2A) receptor blockadeQ40722338
Adenosine kinase is a target for the prediction and prevention of epileptogenesis in miceQ41862804
Silk fibroin as an organic polymer for controlled drug deliveryQ42038479
Electrospun silk-BMP-2 scaffolds for bone tissue engineeringQ42038481
Reactions of 1-N6-ethenoadenosine nucleotides with myosin subfragment 1 and acto-subfragment 1 of skeletal and smooth muscle.Q42250275
Adenosine and ATP link PCO2 to cortical excitability via pH.Q42530690
Adeno-associated virus-mediated expression and constitutive secretion of NPY or NPY13-36 suppresses seizure activity in vivoQ43051288
Rat brain expresses serum calcium-decreasing factor (caldecrin).Q43828997
Seizure suppression by adenosine-releasing cells is independent of seizure frequencyQ44103780
Seizure suppression by adenosine A1 receptor activation in a mouse model of pharmacoresistant epilepsyQ44489270
Decrease of adenosine A1 receptor density and of adenosine neuromodulation in the hippocampus of kindled ratsQ44553318
Focally injected adenosine prevents seizures in the rat.Q45142338
Antiepileptogenic effects of conventional anticonvulsants in the kindling model of epilespyQ45284051
Seizure suppression and lack of adenosine A1 receptor desensitization after focal long-term delivery of adenosine by encapsulated myoblastsQ45882674
Silk microspheres for encapsulation and controlled releaseQ46067219
Adenosine A1 receptor knockout mice develop lethal status epilepticus after experimental traumatic brain injuryQ46668123
Suppression of kindling epileptogenesis by adenosine releasing stem cell-derived brain implants.Q48181919
Enhancing GABA(A) receptor alpha 1 subunit levels in hippocampal dentate gyrus inhibits epilepsy development in an animal model of temporal lobe epilepsy.Q48380900
Adenosine A1 receptors are crucial in keeping an epileptic focus localizedQ48512398
Biomaterial coatings by stepwise deposition of silk fibroin.Q51321790
In vitro degradation of silk fibroin.Q51561651
Three-dimensional aqueous-derived biomaterial scaffolds from silk fibroin.Q51570184
Mechanism of silk processing in insects and spiders.Q51830989
Enzymatic degradation behavior of porous silk fibroin sheets.Q52600760
Adenosine measurement by a rapid HPLC-fluorometric method: induced changes of adenosine content in regions of rat brainQ71606735
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)126-135
P577publication date2009-05-19
P1433published inExperimental NeurologyQ5421127
P1476titleAntiepileptic effects of silk-polymer based adenosine release in kindled rats
P478volume219

Reverse relations

cites work (P2860)
Q42020157A silk platform that enables electrophysiology and targeted drug delivery in brain astroglial cells
Q50662920A1 not A2A adenosine receptors play a role in cortical epileptic afterdischarges in immature rats.
Q34073789Adenosine dysfunction and adenosine kinase in epileptogenesis
Q36036212Adenosine dysfunction in epilepsy
Q34788009Adenosine kinase as a target for therapeutic antisense strategies in epilepsy
Q39553867Adenosine prevents kindled seizures--an effect as smooth as silk
Q48170667Adenosine release during seizures attenuates GABAA receptor-mediated depolarization
Q26785351Adenosine-associated delivery systems
Q36643060Adenosinergic signaling in epilepsy
Q34193177Astrocytes derived from fetal neural progenitor cells as a novel source for therapeutic adenosine delivery.
Q57817412Bioenergetic Mechanisms of Seizure Control
Q35594944Candidate drug targets for prevention or modification of epilepsy
Q35956389Comorbidities in Neurology: Is adenosine the common link?
Q90295794Effect of Silk Fibroin on Neuroregeneration After Traumatic Brain Injury
Q30541877Epigenetic changes induced by adenosine augmentation therapy prevent epileptogenesis.
Q54981587Genome Editing in Neuroepithelial Stem Cells to Generate Human Neurons with High Adenosine-Releasing Capacity.
Q36912637Glial adenosine kinase--a neuropathological marker of the epileptic brain
Q64106725Historical and Current Adenosine Receptor Agonists in Preclinical and Clinical Development
Q35072901Homeostatic bioenergetic network regulation - a novel concept to avoid pharmacoresistance in epilepsy
Q43090447Homeostatic control of brain function - new approaches to understand epileptogenesis.
Q36438511Implantable, multifunctional, bioresorbable optics
Q34349134Incorporation of proteinase inhibitors into silk-based delivery devices for enhanced control of degradation and drug release
Q43161211Ketogenic diet prevents epileptogenesis and disease progression in adult mice and rats
Q35552360Local disruption of glial adenosine homeostasis in mice associates with focal electrographic seizures: a first step in epileptogenesis?
Q34220322Materials fabrication from Bombyx mori silk fibroin
Q34154555Methylxanthines, seizures, and excitotoxicity.
Q34842250Modulators of nucleoside metabolism in the therapy of brain diseases.
Q37042980Neural responses to electrical stimulation on patterned silk films.
Q39126886Novel therapeutic approaches for disease-modification of epileptogenesis for curing epilepsy.
Q92114438Research progress on adenosine in central nervous system diseases
Q37978191Review physical and chemical aspects of stabilization of compounds in silk
Q46236063Silk Fibroin Based Porous Materials.
Q37859773Silk fibroin biomaterials for controlled release drug delivery
Q33846966Silk fibroin encapsulated powder reservoirs for sustained release of adenosine
Q38007146Silk materials--a road to sustainable high technology
Q37714025Silk-based delivery systems of bioactive molecules.
Q26752724The Biochemistry and Epigenetics of Epilepsy: Focus on Adenosine and Glycine
Q34997511Therapeutic epilepsy research: from pharmacological rationale to focal adenosine augmentation
Q34606639Uncoupling of astrogliosis from epileptogenesis in adenosine kinase (ADK) transgenic mice

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