Is the histidine triad nucleotide-binding protein 1 (HINT1) gene a candidate for schizophrenia?

scientific article published on 16 September 2008

Is the histidine triad nucleotide-binding protein 1 (HINT1) gene a candidate for schizophrenia? is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.SCHRES.2008.08.006
P932PMC publication ID2729541
P698PubMed publication ID18799291
P5875ResearchGate publication ID23263289

P50authorKenneth KendlerQ6390313
Xiangning ChenQ67446541
Dermot WalshQ113000839
P2093author name stringQi Chen
Xu Wang
Francis A O'Neill
P2860cites workCharacterization of PKCI and comparative studies with FHIT, related members of the HIT protein familyQ22003944
Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophreniaQ24306904
A note on exact tests of Hardy-Weinberg equilibriumQ24531633
Genome scan meta-analysis of schizophrenia and bipolar disorder, part II: SchizophreniaQ24532517
Domain-wide regulation of gene expression in the human genomeQ24676961
Statistical significance for genomewide studiesQ24681264
Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT MethodQ25938999
The structure of haplotype blocks in the human genomeQ27860500
Haploview: analysis and visualization of LD and haplotype mapsQ27860955
Reduction of nucleoside diphosphate kinase B, Rab GDP-dissociation inhibitor beta and histidine triad nucleotide-binding protein in fetal Down syndrome brainQ28214304
Molecular genetic studies of schizophreniaQ28242041
Making the case for a candidate vulnerability gene in schizophrenia: Convergent evidence for regulator of G-protein signaling 4 (RGS4)Q28253496
Haplotypes spanning SPEC2, PDZ-GEF2 and ACSL6 genes are associated with schizophreniaQ28267685
Maximum-likelihood estimation of molecular haplotype frequencies in a diploid populationQ29614401
Hint1 inhibits growth and activator protein-1 activity in human colon cancer cells.Q30157975
Likelihood-based association analysis for nuclear families and unrelated subjects with missing genotype dataQ31151241
Association study of CSF2RB with schizophrenia in Irish family and case - control samplesQ33668594
A test for linkage and association in general pedigrees: the pedigree disequilibrium testQ34141820
Sex-specific association between bipolar affective disorder in women and GPR50, an X-linked orphan G protein-coupled receptorQ34353797
The histidine triad protein Hint1 interacts with Pontin and Reptin and inhibits TCF-beta-catenin-mediated transcriptionQ34433483
Why sex matters for neuroscienceQ34524235
Estrogen and cytokines production - the possible cause of gender differences in neurological diseases.Q36074614
Association between the neuregulin 1 gene and schizophrenia: a systematic reviewQ36219044
Is the dysbindin gene (DTNBP1) a susceptibility gene for schizophrenia?Q36258629
An update on the genetics of schizophreniaQ36448169
Transcription and chromatin organization of a housekeeping gene cluster containing an integrated beta-globin locus control regionQ36491900
Making connections: boundaries and insulators in DrosophilaQ36955157
A highly significant association between a COMT haplotype and schizophrenia.Q37203703
Gene expression of metabolic enzymes and a protease inhibitor in the prefrontal cortex are decreased in schizophreniaQ38340511
Microarray analysis of gene expression in the prefrontal cortex in schizophrenia: a preliminary studyQ38362304
The role of gender differences in the reduction of etiologic heterogeneity in schizophreniaQ40834511
Support for a possible schizophrenia vulnerability locus in region 5q22-31 in Irish familiesQ44618632
Clinical features of schizophrenia and linkage to chromosomes 5q, 6p, 8p, and 10p in the Irish Study of High-Density Schizophrenia FamiliesQ44869167
Genome-wide scans of three independent sets of 90 Irish multiplex schizophrenia families and follow-up of selected regions in all families provides evidence for multiple susceptibility genesQ44889063
FP-TDI SNP scoring by manual and statistical procedures: a study of error rates and typesQ44892987
Interleukin 3 and schizophrenia: the impact of sex and family historyQ44925637
Supersensitivity to amphetamine in protein kinase-C interacting protein/HINT1 knockout miceQ48319544
Gender-specific association of insertion/deletion polymorphisms in the nogo gene and chronic schizophreniaQ48856990
Pedigree disequilibrium tests for multilocus haplotypes.Q52010978
Implementing a unified approach to family-based tests of association.Q52072093
Probing long-distance regulatory interactions in the Drosophila melanogaster bithorax complex using Dam identification.Q52669864
A genome-wide autosomal screen for schizophrenia susceptibility loci in 71 families with affected siblings: support for loci on chromosome 10p and 6Q59791687
Evidence suggestive of a locus on chromosome 5q31 contributing to susceptibility for schizophrenia in German and Israeli families by multipoint affected sib-pair linkage analysisQ73230984
Allelic discrimination using fluorogenic probes and the 5' nuclease assayQ74618454
P433issue2-3
P407language of work or nameEnglishQ1860
P921main subjectschizophreniaQ41112
P304page(s)200-207
P577publication date2008-09-16
P1433published inSchizophrenia ResearchQ7431607
P1476titleIs the histidine triad nucleotide-binding protein 1 (HINT1) gene a candidate for schizophrenia?
P478volume106

Reverse relations

cites work (P2860)
Q27671245A new crystal form of human histidine triad nucleotide-binding protein 1 (hHINT1) in complex with adenosine 5′-monophosphate at 1.38 Å resolution
Q44977420Acute behavioral effects of nicotine in male and female HINT1 knockout mice
Q33498943Apoptotic engulfment pathway and schizophrenia
Q33816462Association of the histidine-triad nucleotide-binding protein-1 (HINT1) gene variants with nicotine dependence
Q30239953Axonal neuropathy with neuromyotonia: there is a HINT.
Q42872711Cannabinoid receptors couple to NMDA receptors to reduce the production of NO and the mobilization of zinc induced by glutamate.
Q36189837Convergent functional genomics of schizophrenia: from comprehensive understanding to genetic risk prediction.
Q48874499Differential expression of HINT1 in schizophrenia brain tissue
Q42517534Effects of Hint1 deficiency on emotional-like behaviors in mice under chronic immobilization stress.
Q42317501Endocannabinoid control of glutamate NMDA receptors: the therapeutic potential and consequences of dysfunction
Q43105205Expression, purification, crystallization and preliminary X-ray crystallographic analysis of human histidine triad nucleotide-binding protein 2 (hHINT2).
Q34820601Germline polymorphisms discovered via a cell-based, genome-wide approach predict platinum response in head and neck cancers
Q47204896HINT1 in Neuropsychiatric Diseases: A Potential Neuroplastic Mediator
Q36948351Hint1 gene deficiency enhances the supraspinal nociceptive sensitivity in mice.
Q28506405Histidine triad nucleotide-binding protein 1 (HINT1) regulates Ca(2+) signaling in mouse fibroblasts and neuronal cells via store-operated Ca(2+) entry pathway
Q33927060Identification of novel schizophrenia loci by homozygosity mapping using DNA microarray analysis
Q41572995Interactions between the Kynurenine and the Endocannabinoid System with Special Emphasis on Migraine
Q41912346Kinetic mechanism of human histidine triad nucleotide binding protein 1.
Q38432031Post-translational modification of HINT1 mediates activation of MITF transcriptional activity in human melanoma cells.
Q90662958Second messenger Ap4A polymerizes target protein HINT1 to transduce signals in FcεRI-activated mast cells
Q38153348Sex differences in the genetic risk for schizophrenia: history of the evidence for sex-specific and sex-dependent effects
Q42701910Social isolation induces schizophrenia-like behavior potentially associated with HINT1, NMDA receptor 1, and dopamine receptor 2.
Q38262682The ON:OFF switch, σ1R-HINT1 protein, controls GPCR-NMDA receptor cross-regulation: implications in neurological disorders
Q51750311The calcium-sensitive Sigma-1 receptor prevents cannabinoids from provoking glutamate NMDA receptor hypofunction: implications in antinociception and psychotic diseases.
Q34659000The cannabinoid receptor 1 associates with NMDA receptors to produce glutamatergic hypofunction: implications in psychosis and schizophrenia.