| P2093 | author name string | Xia Li | |
| | Athina Markou | |
| | Svetlana Semenova | |
| | Astrid K Stoker | |
| | Manoranjan S D'Souza | |
| P2860 | cites work | The effect of N-acetylcysteine in the nucleus accumbens on neurotransmission and relapse to cocaine | Q24631216 |
| | The mGluR2 positive allosteric modulator BINA decreases cocaine self-administration and cue-induced cocaine-seeking and counteracts cocaine-induced enhancement of brain reward function in rats | Q24631402 |
| | Positive modulation of GABA(B) receptors decreased nicotine self-administration and counteracted nicotine-induced enhancement of brain reward function in rats | Q24647023 |
| | Neurocircuitry of addiction | Q24647156 |
| | Metabotropic glutamate 5 receptor (mGluR5) antagonists decrease nicotine seeking, but do not affect the reinforcement enhancing effects of nicotine | Q24655916 |
| | Ceftriaxone restores glutamate homeostasis and prevents relapse to cocaine seeking | Q24656626 |
| | Reduced inhibitory action of a GABAB receptor agonist on [3H]-dopamine release from rat ventral tegmental area in vitro after chronic nicotine administration | Q24792017 |
| | Update on pharmacologic options for smoking cessation treatment | Q37110429 |
| | Further evidence for an association between the gamma-aminobutyric acid receptor A, subunit 4 genes on chromosome 4 and Fagerström Test for Nicotine Dependence | Q37121556 |
| | NMDA receptors regulate nicotine-enhanced brain reward function and intravenous nicotine self-administration: role of the ventral tegmental area and central nucleus of the amygdala | Q37125141 |
| | Genome-wide association study of smoking initiation and current smoking | Q37156043 |
| | A prospective examination of distress tolerance and early smoking lapse in adult self-quitters | Q37164796 |
| | Effects of baclofen on conditioned rewarding and discriminative stimulus effects of nicotine in rats | Q37185374 |
| | Role of the glutamatergic system in nicotine dependence : implications for the discovery and development of new pharmacological smoking cessation therapies | Q37242594 |
| | The relevance and treatment of cue-induced cravings in tobacco dependence | Q37248093 |
| | Effects of the beta-lactam antibiotic ceftriaxone on nicotine withdrawal and nicotine-induced reinstatement of preference in mice | Q37291940 |
| | Multiple motivational forces contribute to nicotine dependence. | Q37327397 |
| | Dopamine signaling differences in the nucleus accumbens and dorsal striatum exploited by nicotine | Q37344627 |
| | Glutamate and reinstatement | Q37373960 |
| | The neuronal pathways mediating the behavioral and addictive properties of nicotine | Q37382310 |
| | A systematic review of the effectiveness of smoking relapse prevention interventions for abstinent smokers. | Q37775077 |
| | Electrophysiology of GABAA and GABAB receptor subtypes | Q38198238 |
| | GABAB receptors and their significance in mammalian pharmacology | Q38321088 |
| | Redox modulatory site of the NMDA receptor-channel complex: regulation by oxidized glutathione | Q39243254 |
| | Induction of Nrf2 and xCT are involved in the action of the neuroprotective antibiotic ceftriaxone in vitro. | Q39810412 |
| | Behavioral evaluation of mice deficient in GABA(B(1)) receptor isoforms in tests of unconditioned anxiety. | Q40462255 |
| | The scientific case that nicotine is addictive. | Q40510452 |
| | Animal models of drug craving | Q40601523 |
| | Fear-potentiated startle: a neural and pharmacological analysis | Q40729201 |
| | Abuse liability and pharmacodynamic characteristics of intravenous and inhaled nicotine | Q41500106 |
| | Upregulation of ionotropic glutamate receptor subunits within specific mesocorticolimbic regions during chronic nicotine self-administration | Q41619159 |
| | Reward and somatic changes during precipitated nicotine withdrawal in rats: centrally and peripherally mediated effects. | Q41721406 |
| | Preferential increase of extracellular dopamine in the rat nucleus accumbens shell as compared to that in the core during acquisition and maintenance of intravenous nicotine self-administration | Q42488958 |
| | Activation of metabotropic glutamate receptor 5 has direct excitatory effects and potentiates NMDA receptor currents in neurons of the subthalamic nucleus. | Q42495060 |
| | Nicotine-induced conditioned place preference in rats: sex differences and the role of mGluR5 receptors | Q43260721 |
| | Effects of a single dose of baclofen on self-reported subjective effects and tobacco smoking | Q43638196 |
| | The nicotinic antagonist methyllycaconitine has differential effects on nicotine self-administration and nicotine withdrawal in the rat. | Q43788914 |
| | The mGluR5 antagonist MPEP reduces the conditioned rewarding effects of cocaine but not other drugs of abuse. | Q43888946 |
| | Nicotine potentiation of brain stimulation reward reversed by DH beta E and SCH 23390, but not by eticlopride, LY 314582 or MPEP in rats | Q43893928 |
| | Systemic administration of 1R,4S-4-amino-cyclopent-2-ene-carboxylic acid, a reversible inhibitor of GABA transaminase, blocks expression of conditioned place preference to cocaine and nicotine in rats | Q43916637 |
| | Synaptic mechanisms underlie nicotine-induced excitability of brain reward areas | Q43925474 |
| | Increased GABA neurotransmission via administration of gamma-vinyl GABA decreased nicotine self-administration in the rat. | Q43976828 |
| | The effects of the mGluR5 receptor antagonist 6-methyl-2-(phenylethynyl)-pyridine (MPEP) on the stimulation of dopamine release evoked by nicotine in the rat brain | Q44138590 |
| | Selective blockade of drug-induced place preference conditioning by ACPC, a functional NDMA-receptor antagonist. | Q44216533 |
| | Response of nicotine self-administration in the rat to manipulations of mu-opioid and gamma-aminobutyric acid receptors in the ventral tegmental area | Q44331544 |
| | Group II metabotropic and alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA)/kainate glutamate receptors regulate the deficit in brain reward function associated with nicotine withdrawal in rats | Q44477400 |
| | The GABA B receptor agonists baclofen and CGP44532 decreased nicotine self-administration in the rat | Q44650861 |
| | Metabotropic glutamate 5 receptor antagonist MPEP decreased nicotine and cocaine self-administration but not nicotine and cocaine-induced facilitation of brain reward function in rats | Q44698847 |
| | Nicotine-induced dopamine release in the nucleus accumbens is inhibited by the novel AMPA antagonist ZK200775 and the NMDA antagonist CGP39551. | Q44847053 |
| | Construct validity of a self-stimulation threshold paradigm: Effects of reward and performance manipulations | Q44979706 |
| | Repeated administration of the GABAB receptor agonist CGP44532 decreased nicotine self-administration, and acute administration decreased cue-induced reinstatement of nicotine-seeking in rats | Q44987790 |
| | Efficacy and tolerability of an mGlu2/3 agonist in the treatment of generalized anxiety disorder | Q28241583 |
| | A role for nucleus accumbens glutamate transmission in the relapse to cocaine-seeking behavior | Q28373340 |
| | Conditional knockout of NMDA receptors in dopamine neurons prevents nicotine-conditioned place preference | Q28472422 |
| | Subunit composition of functional nicotinic receptors in dopaminergic neurons investigated with knock-out mice | Q28506626 |
| | A pharmacologic strategy for the treatment of nicotine addiction | Q28569945 |
| | Unveiling the functions of presynaptic metabotropic glutamate receptors in the central nervous system | Q28579812 |
| | Baclofen antagonizes nicotine-, cocaine-, and morphine-induced dopamine release in the nucleus accumbens of rat | Q28583983 |
| | Acetylcholine receptors containing the beta2 subunit are involved in the reinforcing properties of nicotine | Q28589593 |
| | Novel genes identified in a high-density genome wide association study for nicotine dependence | Q28943515 |
| | Forced Abstinence Model of Relapse to Study Pharmacological Treatments of Substance Use Disorder | Q28972223 |
| | The reinstatement model of drug relapse: history, methodology and major findings | Q29616241 |
| | Recent advances in the phencyclidine model of schizophrenia | Q29618917 |
| | Orally active metabotropic glutamate subtype 2 receptor positive allosteric modulators: structure-activity relationships and assessment in a rat model of nicotine dependence | Q30446806 |
| | Significant association of glutamate receptor, ionotropic N-methyl-D-aspartate 3A (GRIN3A), with nicotine dependence in European- and African-American smokers | Q30449945 |
| | Nicotine withdrawal increases threat-induced anxiety but not fear: neuroadaptation in human addiction. | Q30473722 |
| | Potentiated startle as a measure of the negative affective consequences of repeated exposure to nicotine in rats | Q30481574 |
| | Anxiety sensitivity and anxiety and depressive symptoms in the prediction of early smoking lapse and relapse during smoking cessation treatment | Q30486877 |
| | Subtypes of nicotinic acetylcholine receptors in nicotine reward, dependence, and withdrawal: evidence from genetically modified mice. | Q30487079 |
| | Spontaneous nicotine withdrawal potentiates the effects of stress in rats | Q30487853 |
| | Affective and somatic aspects of spontaneous and precipitated nicotine withdrawal in C57BL/6J and BALB/cByJ mice | Q30489401 |
| | Fear-potentiated startle to threat, and prepulse inhibition among young adult nonsmokers, abstinent smokers, and nonabstinent smokers | Q30492715 |
| | Comparison of the effects of the GABAB receptor positive modulator BHF177 and the GABAB receptor agonist baclofen on anxiety-like behavior, learning, and memory in mice | Q30539539 |
| | Subregion-specific role of glutamate receptors in the nucleus accumbens on drug context-induced reinstatement of cocaine-seeking behavior in rats | Q30635363 |
| | Glutamate and synaptic plasticity systems and smoking behavior: results from a genetic association study | Q31066470 |
| | Involvement of metabotropic glutamate receptor 5 in brain reward deficits associated with cocaine and nicotine withdrawal and somatic signs of nicotine withdrawal | Q33566228 |
| | Corticotropin-releasing factor-1 receptor activation mediates nicotine withdrawal-induced deficit in brain reward function and stress-induced relapse | Q33656596 |
| | Nicotine withdrawal in U.S. smokers with current mood, anxiety, alcohol use, and substance use disorders | Q33716576 |
| | The GABA B agonist baclofen reduces cigarette consumption in a preliminary double-blind placebo-controlled smoking reduction study. | Q33757216 |
| | Nicotinic receptors in the brain: correlating physiology with function | Q33763401 |
| | Varenicline's effects on acute smoking behavior and reward and their association with subsequent abstinence | Q33824199 |
| | Efficacy of varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, vs placebo or sustained-release bupropion for smoking cessation: a randomized controlled trial | Q33997418 |
| | Therapeutic potential of NMDA receptor antagonists in the treatment of alcohol and substance use disorders | Q34075093 |
| | Neural mechanisms underlying nicotine addiction: acute positive reinforcement and withdrawal | Q34079795 |
| | Synaptic plasticity and nicotine addiction | Q34087642 |
| | Redox modulation of the NMDA receptor | Q34090491 |
| | Role of α7- and β4-containing nicotinic acetylcholine receptors in the affective and somatic aspects of nicotine withdrawal: studies in knockout mice | Q35831006 |
| | Alpha7 nicotinic acetylcholine receptors modulate motivation to self-administer nicotine: implications for smoking and schizophrenia | Q35837691 |
| | mGluR5 receptors in the basolateral amygdala and nucleus accumbens regulate cue-induced reinstatement of ethanol-seeking behavior | Q35846295 |
| | DeltaFosB: a molecular switch for long-term adaptation in the brain | Q35974744 |
| | Ionotropic and metabotropic glutamate receptor structure and pharmacology | Q36054635 |
| | CRF-CRF1 system activation mediates withdrawal-induced increases in nicotine self-administration in nicotine-dependent rats | Q36089365 |
| | Psychostimulant withdrawal as an inducing condition in animal models of depression. | Q36127593 |
| | Neuronal nicotinic acetylcholine receptors: neuroplastic changes underlying alcohol and nicotine addictions | Q36137598 |
| | Critical assessment of how to study addiction and its treatment: human and non-human animal models | Q36267496 |
| | Complex interactions between nicotine and nonpharmacological stimuli reveal multiple roles for nicotine in reinforcement. | Q36293008 |
| | Prediction of lapse from associations between smoking and situational antecedents assessed by ecological momentary assessment | Q36462579 |
| | Metabotropic glutamate receptors. | Q36539070 |
| | Development of novel pharmacotherapeutics for tobacco dependence: progress and future directions | Q36727844 |
| | GABA levels in the dorsal anterior cingulate cortex associated with difficulty ignoring smoking-related cues in tobacco-dependent volunteers. | Q36775258 |
| | Animal models and treatments for addiction and depression co-morbidity | Q36797967 |
| | Effects of pregabalin on smoking behavior, withdrawal symptoms, and cognitive performance in smokers | Q36845975 |
| | The role of negative affect in risk for early lapse among low distress tolerance smokers | Q36944989 |
| | N-acetylcysteine decreased nicotine self-administration and cue-induced reinstatement of nicotine seeking in rats: comparison with the effects of N-acetylcysteine on food responding and food seeking | Q36971440 |
| | Review. Neurobiology of nicotine dependence | Q37024161 |
| | Unraveling the neurobiology of nicotine dependence using genetically engineered mice | Q37076206 |
| | Neurobiological substrates for the dark side of compulsivity in addiction | Q37088658 |
| | Altered response to benzodiazepine anxiolytics in mice lacking GABA B(1) receptors | Q45024856 |
| | Dramatic decreases in brain reward function during nicotine withdrawal. | Q45931115 |
| | Baclofen prevents drug-induced reinstatement of extinguished nicotine-seeking behaviour and nicotine place preference in rodents | Q46105225 |
| | Regulation of cocaine-induced reinstatement by group II metabotropic glutamate receptors in the ventral tegmental area | Q46230643 |
| | Metabotropic glutamate 2/3 receptor activation induced reward deficits but did not aggravate brain reward deficits associated with spontaneous nicotine withdrawal in rats | Q46331107 |
| | Nicotine dependence, depression, and gender: characterizing phenotypes based on withdrawal discomfort, response to smoking, and ability to abstain | Q46417098 |
| | Metabotropic glutamate 2/3 receptors in the ventral tegmental area and the nucleus accumbens shell are involved in behaviors relating to nicotine dependence. | Q46450372 |
| | Prolonged nicotine exposure does not alter GABA(B) receptor-mediated regulation of brain reward function. | Q46591239 |
| | Gamma-aminobutyric acid receptor genes and nicotine dependence: evidence for association from a case-control study | Q46594088 |
| | Differential involvement of glutamatergic mechanisms in the cognitive and subjective effects of smoking. | Q46640365 |
| | Glutamate release in the nucleus accumbens core is necessary for heroin seeking. | Q46691821 |
| | Smoking and alcoholism target genes associated with plasticity and glutamate transmission in the human ventral tegmental area | Q46956901 |
| | The mGluR5 antagonist 2-methyl-6-(phenylethynyl)-pyridine (MPEP) potentiates conditioned place preference induced by various addictive and non-addictive drugs in rats | Q48152436 |
| | Systemic nicotine-induced dopamine release in the rat nucleus accumbens is regulated by nicotinic receptors in the ventral tegmental area | Q48207895 |
| | GABAB receptor-positive modulation-induced blockade of the rewarding properties of nicotine is associated with a reduction in nucleus accumbens DeltaFosB accumulation | Q48313805 |
| | Antagonism of CRF receptors prevents the deficit in brain reward function associated with precipitated nicotine withdrawal in rats | Q48432702 |
| | A unique role for striatal serotonergic systems in the withdrawal from adolescent nicotine administration | Q48443421 |
| | Acute behavioural responses to nicotine and nicotine withdrawal syndrome are modified in GABA(B1) knockout mice | Q48462484 |
| | Altered anxiety and depression-related behaviour in mice lacking GABAB(2) receptor subunits. | Q48498588 |
| | N-methyl-D-aspartate receptor antagonism in the ventral tegmental area diminishes the systemic nicotine-induced dopamine release in the nucleus accumbens | Q48522936 |
| | Reduced dopamine output in the nucleus accumbens but not in the medial prefrontal cortex in rats displaying a mecamylamine-precipitated nicotine withdrawal syndrome | Q48528650 |
| | Behavioural and biochemical adaptations to nicotine in rats: influence of MK801, an NMDA receptor antagonist | Q48586006 |
| | Signs and symptoms of tobacco withdrawal | Q49016637 |
| | Smoking relapse situations: a preliminary typology. | Q51224685 |
| | Self-administered nicotine activates the mesolimbic dopamine system through the ventral tegmental area. | Q51627333 |
| | mGlu1 receptor blockade attenuates cue- and nicotine-induced reinstatement of extinguished nicotine self-administration behavior in rats. | Q52007218 |
| | Nicotine as a reinforcer in human subjects and laboratory animals. | Q52278630 |
| | A genomic scan for habitual smoking in families of alcoholics: common and specific genetic factors in substance dependence. | Q52285242 |
| | Intracellular cysteine and glutathione delivery systems. | Q54435685 |
| | Efficacy of N-Acetylcysteine in the Treatment of Nicotine Dependence: A Double-Blind Placebo-Controlled Pilot Study | Q63361711 |
| | Rodent model of nicotine abstinence syndrome | Q67591174 |
| | Changes after quitting cigarette smoking | Q71140714 |
| | Effects of nicotine withdrawal on central dopaminergic systems | Q71675491 |
| | Nicotine enhancement of fast excitatory synaptic transmission in CNS by presynaptic receptors | Q71768164 |
| | Putative role of presynaptic alpha7* nicotinic receptors in nicotine stimulated increases of extracellular levels of glutamate and aspartate in the ventral tegmental area | Q73109938 |
| | Dissociation of physical abstinence signs from changes in extracellular dopamine in the nucleus accumbens and in the prefrontal cortex of nicotine dependent rats | Q73434121 |
| | Systemic nicotine stimulates dopamine release in nucleus accumbens: re-evaluation of the role of N-methyl-D-aspartate receptors in the ventral tegmental area | Q74016621 |
| | Ability of baclofen to prevent somatic manifestations and neurochemical changes during nicotine withdrawal | Q84512723 |
| | Allosteric binding sites on cell-surface receptors: novel targets for drug discovery | Q34139176 |
| | The mGluR5 antagonist MPEP decreased nicotine self-administration in rats and mice | Q34189168 |
| | Anxiolytic effects of a novel group II metabotropic glutamate receptor agonist (LY354740) in the fear-potentiated startle paradigm in humans | Q34192256 |
| | Neuronal mechanisms underlying development of nicotine dependence: implications for novel smoking-cessation treatments. | Q34224871 |
| | Shape of the relapse curve and long-term abstinence among untreated smokers | Q34284019 |
| | MGS0039: a potent and selective group II metabotropic glutamate receptor antagonist with antidepressant-like activity. | Q34299925 |
| | Genetic and pharmacological evidence of a role for GABA(B) receptors in the modulation of anxiety- and antidepressant-like behavior. | Q34308231 |
| | Behavioral characterization of the novel GABAB receptor-positive modulator GS39783 (N,N'-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine): anxiolytic-like activity without side effects associated with baclofen or benzodiazepines | Q34317012 |
| | The metabotropic glutamate receptor 5 antagonist MPEP decreased break points for nicotine, cocaine and food in rats | Q34379752 |
| | Beta-lactam antibiotics offer neuroprotection by increasing glutamate transporter expression. | Q34382218 |
| | Nicotine induces conditioned place preferences over a large range of doses in rats. | Q34402486 |
| | Psychotogenicity and N-methyl-D-aspartate receptor antagonism: implications for neuroprotective pharmacotherapy. | Q34415261 |
| | Metabotropic glutamate receptor (mGluR5) antagonist MPEP attenuated cue- and schedule-induced reinstatement of nicotine self-administration behavior in rats. | Q34434438 |
| | Ionotropic and metabotropic glutamate receptor antagonism attenuates cue-induced cocaine seeking | Q34445929 |
| | A metabotropic glutamate 2/3 receptor antagonist, MGS0039, increases extracellular dopamine levels in the nucleus accumbens shell. | Q34460773 |
| | Cue dependency of nicotine self-administration and smoking. | Q34498025 |
| | Assessing antidepressant activity in rodents: recent developments and future needs | Q34635853 |
| | Effects of GABA(B) receptor antagonist, agonists and allosteric positive modulator on the cocaine-induced self-administration and drug discrimination | Q34663012 |
| | Both GABA(B) receptor activation and blockade exacerbated anhedonic aspects of nicotine withdrawal in rats | Q34696292 |
| | Evaluation of the anxiolytic-like profile of the GABAB receptor positive modulator CGP7930 in rodents | Q34760168 |
| | Repeated administration of the GABAB receptor positive modulator BHF177 decreased nicotine self-administration, and acute administration decreased cue-induced reinstatement of nicotine seeking in rats | Q34770872 |
| | Nicotine-mediated activation of dopaminergic neurons in distinct regions of the ventral tegmental area | Q34797496 |
| | A 'crash' course on psychostimulant withdrawal as a model of depression | Q34942884 |
| | A role for glutamate in subjective response to smoking and its action on inhibitory control | Q35035848 |
| | Group II metabotropic glutamate receptors (mGlu2/3) in drug addiction | Q35154064 |
| | The metabotropic glutamate 2/3 receptor agonist LY379268 blocked nicotine-induced increases in nucleus accumbens shell dopamine only in the presence of a nicotine-associated context in rats | Q35171303 |
| | Effects of mGluR1 antagonism in the dorsal hippocampus on drug context-induced reinstatement of cocaine-seeking behavior in rats | Q35239835 |
| | Metabotropic glutamate receptor 5 antagonist 2-methyl-6-(phenylethynyl)pyridine (MPEP) microinfusions into the nucleus accumbens shell or ventral tegmental area attenuate the reinforcing effects of nicotine in rats | Q35291239 |
| | Withdrawal from chronic nicotine exposure alters dopamine signaling dynamics in the nucleus accumbens | Q35583364 |
| | Interactive effects of the mGlu5 receptor antagonist MPEP and the mGlu2/3 receptor antagonist LY341495 on nicotine self-administration and reward deficits associated with nicotine withdrawal in rats | Q35647607 |
| | Allosteric modulation of G-protein coupled receptors. | Q35681406 |
| | Genetic linkage to chromosome 22q12 for a heavy-smoking quantitative trait in two independent samples | Q35752604 |
| | The ups and downs of addiction: role of metabotropic glutamate receptors | Q35761628 |
| P921 | main subject | nicotine | Q12144 |
| | pharmacotherapy | Q701216 |
| | nicotine dependence | Q18553444 |
| P1104 | number of pages | 12 | |
| P304 | page(s) | 554-565 | |
| P577 | publication date | 2013-06-07 | |
| P1433 | published in | Neuropharmacology | Q15332439 |
| P1476 | title | Involvement of glutamatergic and GABAergic systems in nicotine dependence: Implications for novel pharmacotherapies for smoking cessation | |
| P478 | volume | 76 Pt B | |