Ethanol inhibits L1 cell adhesion molecule tyrosine phosphorylation and dephosphorylation and activation of pp60(src).

scientific article published on 03 May 2009

Ethanol inhibits L1 cell adhesion molecule tyrosine phosphorylation and dephosphorylation and activation of pp60(src). is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/J.1471-4159.2009.06143.X
P932PMC publication ID2730836
P698PubMed publication ID19457108
P5875ResearchGate publication ID24441343

P50authorVance P. LemmonQ37374728
Cynthia BearerQ46530986
P2093author name stringMin He
Mary Ann O'Riordan
Ningfeng Tang
Natalie K Yeaney
Alfred T Malouf
P2860cites workActivation of the MAPK signal cascade by the neural cell adhesion molecule L1 requires L1 internalizationQ27863662
Recycling of the cell adhesion molecule L1 in axonal growth cones.Q27863668
A MAP kinase-signaling pathway mediates neurite outgrowth on L1 and requires Src-dependent endocytosis.Q27863669
The neural cell adhesion molecule L1 interacts with the AP-2 adaptor and is endocytosed via the clathrin-mediated pathwayQ27867713
Inhibition of insulin-like growth factor-I signaling by ethanol in neuronal cellsQ28212749
Phosphorylation of c-Cbl protooncogene product following ethanol administration in rat cerebellum: possible involvement of Fyn kinaseQ28567054
Decreased insulin-dependent glucose transport by chronic ethanol feeding is associated with dysregulation of the Cbl/TC10 pathway in rat adipocytesQ28574527
Scaffolding of Fyn kinase to the NMDA receptor determines brain region sensitivity to ethanolQ28577315
Ethanol inhibits L1 cell adhesion molecule activation of mitogen-activated protein kinasesQ28578167
A series of normal stages in the development of the chick embryoQ29037347
Signal-dependent membrane protein trafficking in the endocytic pathwayQ29622948
Preferential addition of newly synthesized membrane protein at axonal growth conesQ30465140
Migration of nerve growth cones requires detergent-resistant membranes in a spatially defined and substrate-dependent manner.Q30720712
A review of the neuroanatomical findings in children with fetal alcohol syndrome or prenatal exposure to alcohol.Q32064418
L1-mediated branching is regulated by two ezrin-radixin-moesin (ERM)-binding sites, the RSLE region and a novel juxtamembrane ERM-binding region.Q33814235
A neuronal form of the cell adhesion molecule L1 contains a tyrosine-based signal required for sorting to the axonal growth cone.Q34022650
Neural adhesion molecule L1 as a member of the immunoglobulin superfamily with binding domains similar to fibronectinQ34178138
Mechanisms of brain injury: L1 cell adhesion molecule as a target for ethanol-induced prenatal brain injury.Q34314431
Ethanol inhibits L1-mediated neurite outgrowth in postnatal rat cerebellar granule cellsQ34342439
An L1-like molecule, the 8D9 antigen, is a potent substrate for neurite extensionQ34361199
Tyrosine phosphorylation at a site highly conserved in the L1 family of cell adhesion molecules abolishes ankyrin binding and increases lateral mobility of neurofascinQ34426198
L1 endocytosis is controlled by a phosphorylation-dephosphorylation cycle stimulated by outside-in signaling by L1.Q36324600
Ankyrin binding mediates L1CAM interactions with static components of the cytoskeleton and inhibits retrograde movement of L1CAM on the cell surfaceQ36325097
Uncovering multiple axonal targeting pathways in hippocampal neurons.Q36325518
The Arg-Gly-Asp motif in the cell adhesion molecule L1 promotes neurite outgrowth via interaction with the alphavbeta3 integrinQ38610535
Ethanol alters trafficking and functional N-methyl-D-aspartate receptor NR2 subunit ratio via H-Ras.Q40398957
Ethanol alters cellular activation and CD14 partitioning in lipid rafts.Q40422089
Tyrosine 981, a novel ret autophosphorylation site, binds c-Src to mediate neuronal survivalQ40591766
In vitro comparison of the effects of ethanol and acetaldehyde on dorsal root ganglion neuronsQ40970494
A nonneuronal isoform of cell adhesion molecule L1: tissue-specific expression and functional analysisQ41197102
The role of cell adhesion molecules in neurite outgrowth on Müller cellsQ41242258
Ethanol inhibits neural cell-cell adhesionQ41479804
Ankyrin binding activity shared by the neurofascin/L1/NrCAM family of nervous system cell adhesion moleculesQ42695486
Ethanol-induced Cas tyrosine phosphorylation and Fyn kinase activation in rat brainQ44116412
Tyrosine dephosphorylation and ethanol inhibition of N-Methyl-D-aspartate receptor functionQ44283752
Acute ethanol affects phosphorylation state of the NMDA receptor complex: implication of tyrosine phosphatases and protein kinase A.Q44489637
Phospholipase D2 functions as a downstream signaling molecule of MAP kinase pathway in L1-stimulated neurite outgrowth of cerebellar granule neurons.Q44804968
Acute ethanol treatment modulates Toll-like receptor-4 association with lipid raftsQ46909234
Impaired neurite outgrowth of src-minus cerebellar neurons on the cell adhesion molecule L1.Q48153530
Molecular cloning of cDNA encoding the rat neural cell adhesion molecule L1. Two L1 isoforms in the cytoplasmic region are produced by differential splicingQ48211051
L1 knockout mice show dilated ventricles, vermis hypoplasia and impaired exploration patterns.Q48451285
Errors in corticospinal axon guidance in mice lacking the neural cell adhesion molecule L1.Q48502944
How much alcohol should I use in my experiments?Q49147015
The role of dietary fat in alcohol's prenatal effects.Q52170879
Growth cones are actively influenced by substrate-bound adhesion moleculesQ72334896
Ethanol inhibits insulin receptor tyrosine kinaseQ73352321
Pathological missense mutations of neural cell adhesion molecule L1 affect neurite outgrowth and branching on an L1 substrateQ81038302
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectcell adhesionQ187640
phosphorylationQ242736
P1104number of pages12
P304page(s)779-790
P577publication date2009-05-03
P1433published inJournal of NeurochemistryQ6295643
P1476titleEthanol inhibits L1 cell adhesion molecule tyrosine phosphorylation and dephosphorylation and activation of pp60(src).
P478volume110

Reverse relations

cites work (P2860)
Q33859015Alcoholism and alternative splicing of candidate genes
Q99555476Bilirubin inhibits lipid raft dependent functions of L1 cell adhesion molecule in rat pup cerebellar granule neurons
Q34574004Choline partially prevents the impact of ethanol on the lipid raft dependent functions of l1 cell adhesion molecule
Q27015114Connecting teratogen-induced congenital heart defects to neural crest cells and their effect on cardiac function
Q28740550Effects of ethanol and NAP on cerebellar expression of the neural cell adhesion molecule L1
Q30523977Electro-optical BLM chips enabling dynamic imaging of ordered lipid domains.
Q22241225Ethanol and cognition: indirect effects, neurotoxicity and neuroprotection: a review
Q28578158Ethanol causes the redistribution of L1 cell adhesion molecule in lipid rafts
Q28727027Ethanol disrupts axon outgrowth stimulated by netrin-1, GDNF, and L1 by blocking their convergent activation of Src family kinase signaling
Q38222885Ethanol neurotoxicity in the developing cerebellum: underlying mechanisms and implications
Q37129198Fetal alcohol spectrum disorders: research challenges and opportunities
Q36528326L1 cell adhesion molecule signaling is inhibited by ethanol in vivo
Q34104464L1CAM malfunction in the nervous system and human carcinomas
Q47837860Maternal supplementation of nucleotides improves the behavioral development of prenatal ethanol-exposed mice
Q34191211Molecular and behavioral aspects of the actions of alcohol on the adult and developing brain
Q36179616Persistent dose-dependent changes in brain structure in young adults with low-to-moderate alcohol exposure in utero
Q44488943The interaction between cell adhesion molecule L1, matrix metalloproteinase 14, and adenine nucleotide translocator at the plasma membrane regulates L1-mediated neurite outgrowth of murine cerebellar neurons.
Q37056376Toluene disruption of the functions of L1 cell adhesion molecule at concentrations associated with occupational exposures
Q34963477Two alcohol binding residues interact across a domain interface of the L1 neural cell adhesion molecule and regulate cell adhesion.
Q51537975Visualizing the growth and dynamics of liquid-ordered domains during lipid bilayer folding in a microfluidic chip.

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