| scholarly article | Q13442814 |
| P819 | ADS bibcode | 2013PNAS..11018168P |
| P356 | DOI | 10.1073/PNAS.1311382110 |
| P932 | PMC publication ID | 3831490 |
| P698 | PubMed publication ID | 24145437 |
| P5875 | ResearchGate publication ID | 258064157 |
| P50 | author | Ronald Hay | Q21165834 |
| Viviana Galimberti | Q33275494 | ||
| Domenico Mattoscio | Q58883986 | ||
| Archana Varadaraj | Q78799358 | ||
| P2093 | author name string | Ellis G Jaffray | |
| Massimo Tommasino | |||
| Susanna Chiocca | |||
| Claudia Miccolo | |||
| Maria Elena Pozzebon | |||
| P2860 | cites work | The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis | Q22009936 |
| HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing | Q24291102 | ||
| General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia | Q24315006 | ||
| Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1 | Q24316075 | ||
| Twenty proteins containing a C-terminal SOCS box form five structural classes | Q24317684 | ||
| VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases | Q24322407 | ||
| Inhibition of Transcription Elongation by the VHL Tumor Suppressor Protein | Q24336629 | ||
| Binding of the von Hippel-Lindau Tumor Suppressor Protein to Elongin B and C | Q24336712 | ||
| Synthetic peptides define critical contacts between elongin C, elongin B, and the von Hippel-Lindau protein | Q24563543 | ||
| The von Hippel-Lindau tumor-suppressor gene product forms a stable complex with human CUL-2, a member of the Cdc53 family of proteins | Q24564802 | ||
| The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation | Q24654107 | ||
| Hepatitis C Virus Stabilizes Hypoxia-Inducible Factor 1 and Stimulates the Synthesis of Vascular Endothelial Growth Factor | Q27481487 | ||
| The ubiquitin system | Q27860803 | ||
| Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation | Q27860876 | ||
| Function and regulation of cullin-RING ubiquitin ligases | Q28131707 | ||
| Induction of APOBEC3G Ubiquitination and Degradation by an HIV-1 Vif-Cul5-SCF Complex | Q28210666 | ||
| Identification of Elongin C and Skp1 sequences that determine Cullin selection | Q28274516 | ||
| A mechanism for inhibiting the SUMO pathway | Q28293640 | ||
| Degradation of p53 by adenovirus E4orf6 and E1B55K proteins occurs via a novel mechanism involving a Cullin-containing complex | Q29041391 | ||
| Ubiquitination of hypoxia-inducible factor requires direct binding to the beta-domain of the von Hippel-Lindau protein | Q29615928 | ||
| Identification of the von Hippel-Lindau disease tumor suppressor gene | Q29618644 | ||
| Regulation of angiogenesis by hypoxia: role of the HIF system | Q29619187 | ||
| EC5S ubiquitin complex is recruited by KSHV latent antigen LANA for degradation of the VHL and p53 tumor suppressors | Q33261811 | ||
| Role of early region 3 (E3) in pathogenesis of adenovirus disease | Q33858906 | ||
| Heat shock protein 72 is associated with the hepatitis C virus replicase complex and enhances viral RNA replication | Q34107435 | ||
| Ubiquitin/SUMO Modification Regulates VHL Protein Stability and Nucleocytoplasmic Localization | Q34115236 | ||
| Epstein-Barr virus latent membrane protein 1 induces synthesis of hypoxia-inducible factor 1 alpha | Q34346992 | ||
| Loss of VHL confers hypoxia-inducible factor (HIF)-dependent resistance to vesicular stomatitis virus: role of HIF in antiviral response | Q35139337 | ||
| The von Hippel-Lindau tumor suppressor protein is a component of an E3 ubiquitin-protein ligase activity | Q35201819 | ||
| The Elongin BC complex interacts with the conserved SOCS-box motif present in members of the SOCS, ras, WD-40 repeat, and ankyrin repeat families | Q35211894 | ||
| Interactions of HPV E6 and E7 oncoproteins with tumour suppressor gene products | Q35230893 | ||
| Persistent activation of STAT3 by latent Kaposi's sarcoma-associated herpesvirus infection of endothelial cells. | Q35784707 | ||
| Human papillomavirus type 16 E7 oncoprotein associates with the cullin 2 ubiquitin ligase complex, which contributes to degradation of the retinoblastoma tumor suppressor | Q36098917 | ||
| Elongin BC complex prevents degradation of von Hippel-Lindau tumor suppressor gene products | Q37230912 | ||
| The SOCS box encodes a hierarchy of affinities for Cullin5: implications for ubiquitin ligase formation and cytokine signalling suppression | Q37289267 | ||
| The heat shock protein inhibitor Quercetin attenuates hepatitis C virus production | Q37354782 | ||
| Both BC-box motifs of adenovirus protein E4orf6 are required to efficiently assemble an E3 ligase complex that degrades p53. | Q37574153 | ||
| Hepatitis B virus X protein induces angiogenesis by stabilizing hypoxia-inducible factor-1alpha | Q38518574 | ||
| The von Hippel-Lindau Protein pVHL Inhibits Ribosome Biogenesis and Protein Synthesis | Q39161612 | ||
| The adenovirus E4orf6 E3 ubiquitin ligase complex assembles in a novel fashion | Q40157700 | ||
| Role of STAT3 in type I interferon responses. Negative regulation of STAT1-dependent inflammatory gene activation | Q40298486 | ||
| The adenovirus protein Gam1 interferes with sumoylation of histone deacetylase 1. | Q40399035 | ||
| Selective assembly of HIV-1 Vif-Cul5-ElonginB-ElonginC E3 ubiquitin ligase complex through a novel SOCS box and upstream cysteines | Q40485825 | ||
| Activation of heat-shock response by an adenovirus is essential for virus replication. | Q40853100 | ||
| Hypoxia enhances the antiviral activity of interferons | Q41563181 | ||
| The von Hippel-Lindau Tumor Suppressor Protein Is Destabilized by Src: Implications for Tumor Angiogenesis and Progression | Q41612038 | ||
| Insulin induces transcription of target genes through the hypoxia-inducible factor HIF-1alpha /ARNT | Q41954036 | ||
| Histone deacetylase 1 inactivation by an adenovirus early gene product. | Q43950174 | ||
| Germline mutations in the von Hippel-Lindau disease tumor suppressor gene: correlations with phenotype | Q44847029 | ||
| Cutting edge: role of STAT1, STAT3, and STAT5 in IFN-alpha beta responses in T lymphocytes | Q45059138 | ||
| Hypoxia-inducible factor-1alpha is a key regulator of metastasis in a transgenic model of cancer initiation and progression. | Q46042294 | ||
| Overexpression of human papillomavirus type 16 oncoproteins enhances hypoxia-inducible factor 1 alpha protein accumulation and vascular endothelial growth factor expression in human cervical carcinoma cells | Q46198800 | ||
| Targeting SUMO E1 to Ubiquitin Ligases | Q56777120 | ||
| Carbonic anhydrase (CA IX) expression, a potential new intrinsic marker of hypoxia: correlations with tumor oxygen measurements and prognosis in locally advanced carcinoma of the cervix | Q59139010 | ||
| Adenovirus E4orf6 assembles with Cullin5-ElonginB-ElonginC E3 ubiquitin ligase through an HIV/SIV Vif-like BC-box to regulate p53 | Q64377210 | ||
| P4510 | describes a project that uses | ImageJ | Q1659584 |
| P433 | issue | 45 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 18168-18173 | |
| P577 | publication date | 2013-10-21 | |
| P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
| P1476 | title | BC-box protein domain-related mechanism for VHL protein degradation | |
| P478 | volume | 110 |
| Q36295602 | Autophagy regulates UBC9 levels during viral-mediated tumorigenesis. |
| Q53703943 | COX-2/PGE2 Axis Regulates HIF-2α Activity to Promote Hepatocellular Carcinoma Hypoxic Response and Reduce the Sensitivity of Sorafenib Treatment |
| Q59842331 | CRL4 targets Elongin C for ubiquitination and degradation to modulate CRL5 signaling |
| Q35449374 | Expression and in vitro functional analyses of recombinant Gam1 protein |
| Q93166949 | Human Papilloma Virus Increases ΔNp63α Expression in Head and Neck Squamous Cell Carcinoma |
| Q99546534 | Identification of a cullin5-RING E3 ligase transcriptome signature in glioblastoma multiforme |
| Q99371079 | Integrating cullin2-RING E3 ligase as a potential biomarker for glioblastoma multiforme prognosis and radiosensitivity profiling |
| Q38728290 | Newcastle disease virus degrades HIF-1α through proteasomal pathways independent of VHL and p53. |
| Q92390135 | Regulation of Stem Cells by Cullin-RING Ligase |
| Q38881445 | Regulation of cancer stem cells by RING finger ubiquitin ligases |
| Q28305355 | SUMO Ubc9 enzyme as a viral target |
| Q40639013 | Socs36E limits STAT signaling via Cullin2 and a SOCS-box independent mechanism in the Drosophila egg chamber |
| Q35619352 | The SUMO conjugating enzyme UBC9 as a biomarker for cervical HPV infections. |
| Q33602673 | The chicken adenovirus Gam1 protein, an inhibitor of the sumoylation pathway, partially complements ICP0-null mutant herpes simplex virus 1 |
| Q37645058 | USP9X destabilizes pVHL and promotes cell proliferation |
| Q35570286 | VHL negatively regulates SARS coronavirus replication by modulating nsp16 ubiquitination and stability |
| Q49175511 | WSB1 overcomes oncogene-induced senescence by targeting ATM for degradation |
| Q36286769 | WSB1 promotes tumor metastasis by inducing pVHL degradation |
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