Myelin injury induces axonal transport impairment but not AD-like pathology in the hippocampus of cuprizone-fed mice

scientific article published on 25 April 2016

Myelin injury induces axonal transport impairment but not AD-like pathology in the hippocampus of cuprizone-fed mice is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.18632/ONCOTARGET.8981
P932PMC publication ID5058659
P698PubMed publication ID27129150

P2093author name stringFeng Bai
Hong Zhou
Zhijun Zhang
Junjun Sun
Qingguo Ren
P2860cites workMutations in the neurofilament light gene linked to Charcot-Marie-Tooth disease cause defects in transportQ24300855
Fractional anisotropy of the fornix and hippocampal atrophy in Alzheimer's diseaseQ26827268
APP processing in Alzheimer's diseaseQ27694738
In vivo MR imaging of hippocampal lesions in multiple sclerosisQ28270287
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Psychopathology in multiple sclerosis: diagnosis, prevalence and treatmentQ28301691
Kinesin and Dynein Superfamily Proteins and the Mechanism of Organelle TransportQ29620418
Promotion of central nervous system remyelination by induced differentiation of oligodendrocyte precursor cellsQ30051733
NGF regulates the expression of axonal LINGO-1 to inhibit oligodendrocyte differentiation and myelinationQ79485750
Extensive hippocampal demyelination in multiple sclerosisQ81098501
Myelination and the trophic support of long axonsQ83162670
Spinophilin: from partners to functionsQ30159786
White matter tract integrity metrics reflect the vulnerability of late-myelinating tracts in Alzheimer's diseaseQ30711356
Hippocampal volume is related to cognitive decline and fornicial diffusion measures in multiple sclerosis.Q33630918
Dementia in MS complicated by coexistent Alzheimer disease: Diagnosis premortem and postmortemQ34000843
The neurotoxicant, cuprizone, as a model to study demyelination and remyelination in the central nervous system.Q34122755
Application of multimodal MR imaging on studying Alzheimer's disease: a surveyQ34899260
Neurofilaments and neurological diseaseQ35091600
Myelin basic protein associates with AβPP, Aβ1-42, and amyloid plaques in cortex of Alzheimer's disease brainQ35576628
LINGO-1 antibody ameliorates myelin impairment and spatial memory deficits in experimental autoimmune encephalomyelitis miceQ36098974
Oligodendroglial modulation of fast axonal transport in a mouse model of hereditary spastic paraplegia.Q36322059
Multiple sclerosis masquerading as Alzheimer-type dementia: Clinical, radiological and pathological findingsQ36730636
White matter in learning, cognition and psychiatric disordersQ36793946
Triple-transgenic Alzheimer's disease mice exhibit region-specific abnormalities in brain myelination patterns prior to appearance of amyloid and tau pathologyQ36976882
Differential hippocampal shapes in posterior cortical atrophy patients: A comparison with control and typical AD subjectsQ37105510
LINGO-1 and its role in CNS repairQ37158658
Local regulation of neurofilament transport by myelinating cellsQ37594141
Myelination and support of axonal integrity by gliaQ37808620
De- and remyelination in the CNS white and grey matter induced by cuprizone: the old, the new, and the unexpectedQ37942523
Axonal transport deficits and neurodegenerative diseasesQ38077679
Is Alzheimer's a disease of the white matter?Q38089525
Cuprizone-Induced Demyelination as a Tool to Study Remyelination and Axonal ProtectionQ38105989
Releasing the brake: restoring fast axonal transport in neurodegenerative disorders.Q38148914
Dynamics and mechanisms of CNS myelination.Q38364753
Differential patterns of memory performance in relapsing, remitting and secondary progressive multiple sclerosisQ38401923
Similar autobiographical memory impairment in long-term secondary progressive multiple sclerosis and Alzheimer's diseaseQ38470033
Cuprizone [bis(cyclohexylidenehydrazide)] is selectively toxic for mature oligodendrocytes.Q39197680
Can Antibodies Against Glial Derived Antigens be Early Biomarkers of Hippocampal Demyelination and Memory Loss in Alzheimer's Disease?Q40507083
Increased A beta peptides and reduced cholesterol and myelin proteins characterize white matter degeneration in Alzheimer's diseaseQ40634928
Demyelination causes synaptic alterations in hippocampi from multiple sclerosis patientsQ41826954
Hyperphosphorylation and aggregation of tau in experimental autoimmune encephalomyelitisQ45115027
The association between California Verbal Learning Test performance and fibre impairment in multiple sclerosis: evidence from diffusion tensor imagingQ46150266
Charcot-Marie-Tooth disease neurofilament mutations disrupt neurofilament assembly and axonal transportQ48462055
Disconnection as a mechanism for cognitive dysfunction in multiple sclerosisQ48863758
Verbal episodic memory impairment in Alzheimer's disease: a combined structural and functional MRI studyQ49015865
A new mechanism of nervous system plasticity: activity-dependent myelinationQ50548732
Multiple white matter tract abnormalities underlie cognitive impairment in RRMSQ50984137
Regional hippocampal atrophy in multiple sclerosis.Q51960814
Substantial archaeocortical atrophy and neuronal loss in multiple sclerosisQ51964603
LINGO-1 antagonist promotes spinal cord remyelination and axonal integrity in MOG-induced experimental autoimmune encephalomyelitisQ57186801
Multiple sclerosis and Alzheimer's diseaseQ61709524
P433issue21
P407language of work or nameEnglishQ1860
P921main subjectpathologyQ7208
cuprizoneQ27262585
P304page(s)30003-30017
P577publication date2016-04-25
P1433published inOncotargetQ1573155
P1476titleMyelin injury induces axonal transport impairment but not AD-like pathology in the hippocampus of cuprizone-fed mice
P478volume7

Reverse relations

cites work (P2860)
Q57300142Age Influences Microglial Activation After Cuprizone-Induced Demyelination
Q102152326DCX+ neuronal progenitors contribute to new oligodendrocytes during remyelination in the hippocampus
Q48503062LINGO-1 antibody ameliorates myelin impairment and spatial memory deficits in the early stage of 5XFAD mice.
Q90418013Neurofilament relates to white matter microstructure in older adults

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