The paradoxical patterns of expression of indoleamine 2,3-dioxygenase in colon cancer

scientific article published on 20 August 2009

The paradoxical patterns of expression of indoleamine 2,3-dioxygenase in colon cancer is …
instance of (P31):
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1014802447
P356DOI10.1186/1479-5876-7-71
P932PMC publication ID2736158
P698PubMed publication ID19695096
P5875ResearchGate publication ID26755610

P2093author name stringXing Zhang
Yi-Xin Zeng
Jiang Li
Rui-Qing Peng
Xiao-Shi Zhang
Ya Ding
De-Sen Wan
Xiao-Jun Wu
Zhi-Zhong Pan
Yan-Fang Gao
P2860cites workExosomes as a tumor immune escape mechanism: possible therapeutic implicationsQ21245472
Prevention of allogeneic fetal rejection by tryptophan catabolismQ24336018
rIFN-gamma-mediated growth suppression of platinum-sensitive and -resistant ovarian tumor cell lines not dependent upon arginase inhibitionQ24805224
The changes of CD4+CD25+/CD4+ proportion in spleen of tumor-bearing BALB/c miceQ24805327
Progress and controversies in developing cancer vaccinesQ24810256
Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenaseQ28204166
Biochemical and medical aspects of the indoleamine 2,3-dioxygenase-initiated L-tryptophan metabolismQ28273442
Inhibition of indoleamine 2,3-dioxygenase in dendritic cells by stereoisomers of 1-methyl-tryptophan correlates with antitumor responsesQ28283999
IDO expression by dendritic cells: tolerance and tryptophan catabolismQ29614752
Inhibition of indoleamine 2,3-dioxygenase, an immunoregulatory target of the cancer suppression gene Bin1, potentiates cancer chemotherapy.Q34394487
Immune escape as a fundamental trait of cancer: focus on IDO.Q34758085
Inhibition of experimental asthma by indoleamine 2,3-dioxygenaseQ35835456
Expression of indoleamine 2,3-dioxygenase by plasmacytoid dendritic cells in tumor-draining lymph nodes.Q35835489
Plasmacytoid dendritic cells from mouse tumor-draining lymph nodes directly activate mature Tregs via indoleamine 2,3-dioxygenaseQ35925641
Indoleamine 2,3-dioxygenase, tumor-induced tolerance and counter-regulationQ36388171
Tumor-infiltrating macrophages and dendritic cells in human colorectal cancer: relation to local regulatory T cells, systemic T-cell response against tumor-associated antigens and survivalQ36402098
Regulatory T cells, tumour immunity and immunotherapyQ36430144
Immune resistance orchestrated by the tumor microenvironmentQ36593747
The tumor-draining lymph node as an immune-privileged siteQ36593753
Indoleamine 2,3-dioxygenase is a novel prognostic indicator for endometrial cancerQ36612457
Molecules in focus: indoleamine 2,3-dioxygenase.Q36744423
Tryptophan catabolism in IDO+ plasmacytoid dendritic cells.Q36789443
Role of indoleamine 2,3-dioxygenase in antimicrobial defence and immuno-regulation: tryptophan depletion versus production of toxic kynurenines.Q36789457
Indoleamine 2,3-dioxygenase and tumor-induced toleranceQ36809762
Tumor immune escape mediated by indoleamine 2,3-dioxygenaseQ36888330
Is IDO a key enzyme bridging the gap between tumor escape and tolerance induction?Q37026760
Uveal melanoma expression of indoleamine 2,3-deoxygenase: establishment of an immune privileged environment by tryptophan depletionQ37224538
T cell regulatory plasmacytoid dendritic cells expressing indoleamine 2,3 dioxygenaseQ37334065
Inhibitors of indoleamine-2,3-dioxygenase for cancer therapy: can we see the wood for the trees?Q37492248
Foxp3 expression in human cancer cells.Q38524958
A novel cancer therapy by skin delivery of indoleamine 2,3-dioxygenase siRNA.Q39894586
Critical role of indoleamine 2,3-dioxygenase in tumor resistance to repeated treatments with targeted IFNgammaQ39906069
Overexpression of indoleamine 2,3-dioxygenase in human endometrial carcinoma cells induces rapid tumor growth in a mouse xenograft modelQ39916520
Tumor-induced CD11b+Gr-1+ myeloid cells suppress T cell sensitization in tumor-draining lymph nodesQ39949096
Expression of indoleamine 2,3-dioxygenase in metastatic pancreatic ductal adenocarcinoma recruits regulatory T cells to avoid immune detectionQ39983492
Expression and prognosis role of indoleamine 2,3-dioxygenase in hepatocellular carcinomaQ39988114
Expression of indoleamine 2,3-dioxygenase in tumor endothelial cells correlates with long-term survival of patients with renal cell carcinomaQ40041177
Indoleamine 2,3-dioxygenase (IDO) expression in lung cancerQ40093637
Reinstalling antitumor immunity by inhibiting tumor-derived immunosuppressive molecule IDO through RNA interferenceQ40224792
Prognostic value of indoleamine 2,3-dioxygenase expression in colorectal cancer: effect on tumor-infiltrating T cells.Q40314157
Indoleamine 2,3-dioxygenase activity and L-tryptophan transport in human breast cancer cellsQ40589307
Mechanisms of local immunosuppression in cutaneous melanoma.Q41808459
More insights into the immunosuppressive potential of tumor exosomes.Q43237241
Indoleamine 2,3-dioxygenase expression in transplanted NOD Islets prolongs graft survival after adoptive transfer of diabetogenic splenocytes.Q43867525
Inverse correlation between tumoral indoleamine 2,3-dioxygenase expression and tumor-infiltrating lymphocytes in endometrial cancer: its association with disease progression and survivalQ44776511
Expression of indoleamine 2,3-dioxygenase in carcinoma of human endometrium and uterine cervix.Q44943815
Indoleamine 2,3-dioxygenase as a new target for malignant glioma therapy. Laboratory investigation.Q46130460
The immunoregulatory role of IDO-producing human dendritic cells revisitedQ46889954
Enhancement of dendritic cell-tumor fusion vaccine potency by indoleamine-pyrrole 2,3-dioxygenase inhibitor, 1-MT.Q46971502
CD25 and indoleamine 2,3-dioxygenase are up-regulated by prostaglandin E2 and expressed by tumor-associated dendritic cells in vivo: additional mechanisms of T-cell inhibitionQ46979779
Suppression of islet allogeneic immune response by indoleamine 2,3 dioxygenase-expressing fibroblasts.Q50685823
Metastatic tumour cells favour the generation of a tolerogenic milieu in tumour draining lymph node in patients with early cervical cancer.Q51959038
Effect of melanoma on immune function in the regional lymph node basin.Q54548294
Increased synthesis of indoleamine-2,3-dioxygenase protein is positively associated with impaired survival in patients with serous-type, but not with other types of, ovarian cancerQ56786153
THE role of indoleamine 2,3-dioxygenase in the anti-tumour activity of human interferon-γin vivoQ61819257
Ep-CAM overexpression in breast cancer as a predictor of survivalQ73328477
P304page(s)71
P577publication date2009-08-20
P1433published inJournal of Translational MedicineQ15716664
P1476titleThe paradoxical patterns of expression of indoleamine 2,3-dioxygenase in colon cancer
P478volume7

Reverse relations

cites work (P2860)
Q35604318Accumulation of an endogenous tryptophan-derived metabolite in colorectal and breast cancers
Q35653808Clinicopathological significance of indoleamine 2,3-dioxygenase 1 expression in colorectal cancer
Q39308620Concordance of immune checkpoints within tumor immune contexture and their prognostic significance in gastric cancer.
Q35406476Expression and function analysis of indoleamine 2 and 3-dioxygenase in bladder urothelial carcinoma
Q33684895Expression of CXCR-4 and IDO in human colorectal cancer: An immunohistochemical approach
Q24609433Expression of calreticulin is associated with infiltration of T-cells in stage IIIB colon cancer
Q42484093High expression of indoleamine 2,3-dioxygenase in the tumour is associated with medullary features and favourable outcome in basal-like breast carcinoma.
Q37042990IDO1 metabolites activate β-catenin signaling to promote cancer cell proliferation and colon tumorigenesis in mice
Q95660974IDO1+ Paneth cells promote immune escape of colorectal cancer
Q37137360Immune suppression in tumors as a surmountable obstacle to clinical efficacy of cancer vaccines
Q27025063Indoleamine 2,3 dioxygenase in intestinal disease
Q36866163Indoleamine 2,3-dioxygenase activity and clinical outcome following induction chemotherapy and concurrent chemoradiation in Stage III non-small cell lung cancer
Q37362632Indoleamine 2,3-dioxygenase: is it an immune suppressor?
Q54968700Indoleamine-2,3-dioxygenase 1/cyclooxygenase 2 expression prediction for adverse prognosis in colorectal cancer.
Q90176765Inflammation-Induced Tryptophan Breakdown is Related With Anemia, Fatigue, and Depression in Cancer
Q50138585Inflammatory Reprogramming with IDO1 Inhibitors: Turning Immunologically Unresponsive 'Cold' Tumors 'Hot'.
Q42089828Inhibition of indoleamine 2,3-dioxygenase 1 expression alters immune response in colon tumor microenvironment in mice.
Q39623446Interaction of coagulation factors and tumor-associated macrophages mediates migration and invasion of gastric cancer
Q36551083Mast Cells in Adjacent Normal Colon Mucosa rather than Those in Invasive Margin are Related to Progression of Colon Cancer
Q48306002Modulating Tumor Immunology by Inhibiting Indoleamine 2,3-Dioxygenase (IDO): Recent Developments and First Clinical Experiences.
Q35082013No relationship between the distribution of mast cells and the survival of stage IIIB colon cancer patients
Q55351202Peritumoral endothelial indoleamine 2, 3-dioxygenase expression is an early independent marker of disease relapse in colorectal cancer and is influenced by DNA mismatch repair profile.
Q38718929Prevention and treatment of cancers by immune modulating nutrients.
Q53249720Prognostic implications of immunosuppressive protein expression in tumors as well as immune cell infiltration within the tumor microenvironment in gastric cancer.
Q38406396Strong Correlation of Indoleamine 2,3-Dioxygenase 1 Expression with Basal-Like Phenotype and Increased Lymphocytic Infiltration in Triple-Negative Breast Cancer
Q36753355T and NK cells: two sides of tumor immunoevasion
Q33737094The density of macrophages in the invasive front is inversely correlated to liver metastasis in colon cancer
Q36117580The potential role of indoleamine 2,3 dioxygenase (IDO) as a predictive and therapeutic target for diabetes treatment: a mythical truth
Q60442132The role of plasma IDO activity as a diagnostic marker of patients with colorectal cancer
Q38571347Therapeutic targeting of inflammation and tryptophan metabolism in colon and gastrointestinal cancer.
Q52873461Tumor-Associated Fibroblasts and Microvessels Contribute to the Expression of Immunosuppressive Factor Indoleamine 2, 3-Dioxygenase in Human Esophageal Cancers.
Q92480951miR-448 targets IDO1 and regulates CD8+ T cell response in human colon cancer