Whole-genome sequencing for rapid susceptibility testing of M. tuberculosis

scientific article published on July 2013

Whole-genome sequencing for rapid susceptibility testing of M. tuberculosis is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1056/NEJMC1215305
P932PMC publication ID3836233
P698PubMed publication ID23863072

P50authorJulian ParkhillQ16773696
Marc A. Martí‐RenomQ37840429
Claudio U KöserQ42421440
Sharon PeacockQ44172566
Estee TorokQ56550582
Josephine M BryantQ56815996
Matthew J EllingtonQ93060687
Jennifer BecqQ114726638
P2093author name stringAndrew J Carmichael
Geoffrey P Smith
P2860cites workRoutine use of microbial whole genome sequencing in diagnostic and public health microbiologyQ28728617
The future of molecular diagnostics for drug-resistant tuberculosisQ30455525
Whole-genome sequencing to delineate Mycobacterium tuberculosis outbreaks: a retrospective observational studyQ31107101
Microevolution of extensively drug-resistant tuberculosis in RussiaQ35864738
Importance of improved TB diagnostics in addressing the extensively drug-resistant TB crisisQ40066961
P433issue3
P407language of work or nameEnglishQ1860
P921main subjecttuberculosisQ12204
Mycobacterium tuberculosisQ130971
whole genome sequencingQ2068526
P304page(s)290-292
P577publication date2013-07-01
P1433published inThe New England Journal of MedicineQ582728
P1476titleWhole-genome sequencing for rapid susceptibility testing of M. tuberculosis
P478volume369

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cites work (P2860)
Q26999868A microbiological revolution meets an ancient disease: improving the management of tuberculosis with genomics
Q28068503Antimicrobial Stewardship: How the Microbiology Laboratory Can Right the Ship
Q37833917Bacterial genome sequencing in clinical microbiology: a pathogen-oriented review
Q86852508Bacterial genome sequencing in the clinic: bioinformatic challenges and solutions
Q42656497Bacterial whole-genome sequencing revisited: portable, scalable, and standardized analysis for typing and detection of virulence and antibiotic resistance genes
Q91706429Beyond multidrug resistance: Leveraging rare variants with machine and statistical learning models in Mycobacterium tuberculosis resistance prediction
Q35311983Capturing the cloud of diversity reveals complexity and heterogeneity of MRSA carriage, infection and transmission
Q34968760Characterizing the genetic basis of bacterial phenotypes using genome-wide association studies: a new direction for bacteriology
Q38268747Classical and new assays for detecting drug resistance in tuberculosis
Q35455573Clinical application of whole-genome sequencing to inform treatment for multidrug-resistant tuberculosis cases
Q92434251Clinical challenges in the era of multiple and extensively drug-resistant tuberculosis
Q30207754Clinical laboratory response to a mock outbreak of invasive bacterial infections: a preparedness study.
Q38901011Clinical metagenomics for the management of hospital- and healthcare-acquired pneumonia.
Q40097858Clinical metagenomics of bone and joint infections: a proof of concept study.
Q26752636Clinical use of whole genome sequencing for Mycobacterium tuberculosis
Q28607255Collaborative Effort for a Centralized Worldwide Tuberculosis Relational Sequencing Data Platform
Q42737698Comment on: characterization of the embB gene in Mycobacterium tuberculosis isolates from Barcelona and rapid detection of main mutations related to ethambutol resistance using a low-density DNA array
Q28546999Comparative Evaluation of Sloppy Molecular Beacon and Dual-Labeled Probe Melting Temperature Assays to Identify Mutations in Mycobacterium tuberculosis Resulting in Rifampin, Fluoroquinolone and Aminoglycoside Resistance
Q90100518Comparative fitness analysis of D-cycloserine resistant mutants reveals both fitness-neutral and high-fitness cost genotypes
Q35915975Comparison of Sample Preparation Methods Used for the Next-Generation Sequencing of Mycobacterium tuberculosis
Q45926221Complex genetics of drug resistance in Mycobacterium tuberculosis.
Q46589487Cryptic Microheteroresistance Explains Mycobacterium tuberculosis Phenotypic Resistance
Q21128711Culture-independent detection and characterisation of Mycobacterium tuberculosis and M. africanum in sputum samples using shotgun metagenomics on a benchtop sequencer
Q92180644Deciphering drug resistance in Mycobacterium tuberculosis using whole-genome sequencing: progress, promise, and challenges
Q36071093Deep Whole-Genome Sequencing to Detect Mixed Infection of Mycobacterium tuberculosis
Q28547220Detection of Low-Level Mixed-Population Drug Resistance in Mycobacterium tuberculosis Using High Fidelity Amplicon Sequencing
Q38682808Diagnosis of Tuberculosis in HIV Co-infected Individuals: Current Status, Challenges and Opportunities for the Future
Q26752536Diagnostic 'omics' for active tuberculosis
Q39524649Differences in T-cell responses between Mycobacterium tuberculosis and Mycobacterium africanum-infected patients
Q92667180Direct transmission of within-host Mycobacterium tuberculosis diversity to secondary cases can lead to variable between-host heterogeneity without de novo mutation: A genomic investigation
Q28551469Discordance across Phenotypic and Molecular Methods for Drug Susceptibility Testing of Drug-Resistant Mycobacterium tuberculosis Isolates in a Low TB Incidence Country
Q54205199Dissecting whole-genome sequencing-based online tools for predicting resistance in Mycobacterium tuberculosis: can we use them for clinical decision guidance?
Q34930530Diversity and evolution of Mycobacterium tuberculosis: moving to whole-genome-based approaches
Q40957415Draft Genome Sequence of a Drug-Susceptible New Zealand Isolate of Mycobacterium tuberculosis Lineage 3.
Q41895871Draft Genome Sequence of a Multidrug-Resistant New Zealand Isolate of Mycobacterium tuberculosis Lineage 3.
Q41765905Draft Genome Sequence of the First Isolate of Extensively Drug-Resistant Mycobacterium tuberculosis in Ireland
Q33584660Draft Genome Sequence of the First Isolate of Extensively Drug-Resistant Mycobacterium tuberculosis in New Zealand
Q38179033Drug resistance to Mycobacterium tuberculosis: from the traditional Chinese view to modern systems biology
Q64234748Drug susceptibility testing and mortality in patients treated for tuberculosis in high-burden countries: a multicentre cohort study
Q92890791Epidemiological cut-offs for Sensititre susceptibility testing of Mycobacterium tuberculosis: interpretive criteria cross validated with whole genome sequencing
Q31148646Evaluation of Machine Learning and Rules-Based Approaches for Predicting Antimicrobial Resistance Profiles in Gram-negative Bacilli from Whole Genome Sequence Data
Q92668753Evolution of Mycobacterium tuberculosis complex lineages and their role in an emerging threat of multidrug resistant tuberculosis in Bamako, Mali
Q47632774Evolution of Phenotypic and Molecular Drug Susceptibility Testing
Q27016579Evolution of drug resistance in tuberculosis: recent progress and implications for diagnosis and therapy
Q60925773First insights on the genetic diversity of MDR Mycobacterium tuberculosis in Lebanon
Q38999525Genetic Determinants of Drug Resistance in Mycobacterium tuberculosis and Their Diagnostic Value
Q42714470Genetic diversity within Mycobacterium tuberculosis complex impacts on the accuracy of genotypic pyrazinamide drug-susceptibility assay
Q36826330Genetic signatures of Mycobacterium tuberculosis Nonthaburi genotype revealed by whole genome analysis of isolates from tuberculous meningitis patients in Thailand.
Q40936781Genome sequencing reveals novel deletions associated with secondary resistance to pyrazinamide in MDR Mycobacterium tuberculosis
Q48190673Genome-wide analysis of multi- and extensively drug-resistant Mycobacterium tuberculosis
Q58493506Genomic Analysis of Bacterial Outbreaks
Q35676292Genomic Context of Azole Resistance Mutations in Aspergillus fumigatus Determined Using Whole-Genome Sequencing
Q36844683Genomic and functional analyses of Mycobacterium tuberculosis strains implicate ald in D-cycloserine resistance.
Q38987535Genomic and functional techniques to mine the microbiome for novel antimicrobials and antimicrobial resistance genes
Q38808071Genomics and the evolution of antibiotic resistance
Q42213160Health care: Bring microbial sequencing to hospitals
Q37733149High risk and rapid appearance of multidrug resistance during tuberculosis treatment in Moldova
Q59806888Highlights on the Application of Genomics and Bioinformatics in the Fight Against Infectious Diseases: Challenges and Opportunities in Africa
Q41927847Identification of novel mutations associated with cycloserine resistance in Mycobacterium tuberculosis
Q35193200Integration of whole-genome sequencing into infection control practices: the potential and the hurdles
Q38225730Isoniazid-resistant tuberculosis in Birmingham, United Kingdom, 1999-2010.
Q34340287KvarQ: targeted and direct variant calling from fastq reads of bacterial genomes.
Q35157830Long term effect of gut microbiota transfer on diabetes development
Q41566433Magnitude and sources of bias in the detection of mixed strain M. tuberculosis infection
Q28389409Methodological and Clinical Aspects of the Molecular Epidemiology of Mycobacterium tuberculosis and Other Mycobacteria
Q41599957Microbial sequencing to improve individual and population health
Q49332451Molecular Diagnosis of Tuberculosis.
Q91737856More than merely drug resistance
Q38829192Mycobacterium tuberculosis resistance prediction and lineage classification from genome sequencing: comparison of automated analysis tools
Q35293726New methods for identifying infectious diseases.
Q60907631Next-Generation Whole Genome Sequencing: Opportunities and Challenges
Q38210363Novel diagnostics and therapeutics for drug-resistant tuberculosis
Q41452335Novel laboratory diagnostic tests for tuberculosis and their potential role in an integrated and tiered laboratory network
Q51574982Personalizing therapy for multidrug resistant TB: the potential of Rapid Whole Genome Sequencing.
Q30927278PhyResSE: a Web Tool Delineating Mycobacterium tuberculosis Antibiotic Resistance and Lineage from Whole-Genome Sequencing Data
Q38863350Phylogenetic polymorphisms in antibiotic resistance genes of the Mycobacterium tuberculosis complex
Q55260133Prevalence and patterns of rifampicin and isoniazid resistance conferring mutations in Mycobacterium tuberculosis isolates from Uganda.
Q37546274Pyrosequencing for rapid detection of extensively drug-resistant Mycobacterium tuberculosis in clinical isolates and clinical specimens
Q35933217Pyrosequencing on a glass surface
Q37132034Rapid Drug Susceptibility Testing of Drug-Resistant Mycobacterium tuberculosis Isolates Directly from Clinical Samples by Use of Amplicon Sequencing: a Proof-of-Concept Study
Q35757756Rapid Whole-Genome Sequencing of Mycobacterium tuberculosis Isolates Directly from Clinical Samples
Q27342229Rapid antibiotic-resistance predictions from genome sequence data for Staphylococcus aureus and Mycobacterium tuberculosis
Q35644365Rapid determination of anti-tuberculosis drug resistance from whole-genome sequences
Q36875446Rapid diagnosis of MDR and XDR tuberculosis with the MeltPro TB assay in China
Q35076491Rapid single-colony whole-genome sequencing of bacterial pathogens
Q28603336Rapid, comprehensive, and affordable mycobacterial diagnosis with whole-genome sequencing: a prospective study
Q37434270Real-Time Genome Sequencing of Resistant Bacteria Provides Precision Infection Control in an Institutional Setting.
Q39014173Recent developments in genomics, bioinformatics and drug discovery to combat emerging drug-resistant tuberculosis
Q41991754Role of alanine racemase mutations in Mycobacterium tuberculosis D-cycloserine resistance
Q27004697Systematic review of mutations in pyrazinamidase associated with pyrazinamide resistance in Mycobacterium tuberculosis clinical isolates
Q74434471TB resistance revealed
Q30585056The MedSeq Project: a randomized trial of integrating whole genome sequencing into clinical medicine
Q30235074The epidemiology, pathogenesis, transmission, diagnosis, and management of multidrug-resistant, extensively drug-resistant, and incurable tuberculosis
Q40483822The essential mycobacterial amidotransferase GatCAB is a modulator of specific translational fidelity.
Q39402027The past decade in bench research into pulmonary infectious diseases: What do clinicians need to know?
Q38210265Totally drug-resistant tuberculosis and adjunct therapies.
Q35661922Tracking a tuberculosis outbreak over 21 years: strain-specific single-nucleotide polymorphism typing combined with targeted whole-genome sequencing
Q35868609Transmitted Extended-Spectrum Extensively Drug-Resistant Tuberculosis in Beijing, China, with Discordant Whole-Genome Sequencing Analysis Results
Q57235679Tuberculosis
Q36325978Use of whole-genome sequencing to distinguish relapse from reinfection in a completed tuberculosis clinical trial
Q41431442Validation of β-lactam minimum inhibitory concentration predictions for pneumococcal isolates with newly encountered penicillin binding protein (PBP) sequences
Q46319545What Is Resistance? Impact of Phenotypic versus Molecular Drug Resistance Testing on Therapy for Multi- and Extensively Drug-Resistant Tuberculosis.
Q28547769Whole Genome Sequencing Investigation of a Tuberculosis Outbreak in Port-au-Prince, Haiti Caused by a Strain with a "Low-Level" rpoB Mutation L511P - Insights into a Mechanism of Resistance Escalation
Q91837162Whole genome enrichment approach for rapid detection of Mycobacterium tuberculosis and drug resistance-associated mutations from direct sputum sequencing
Q64117158Whole genome sequencing for drug resistance determination in Mycobacterium tuberculosis
Q50098804Whole genome sequencing for the management of drug-resistant TB in low income high TB burden settings: Challenges and implications
Q34465192Whole genome sequencing in clinical and public health microbiology
Q38828639Whole genome sequencing of Mycobacterium tuberculosis for detection of recent transmission and tracing outbreaks: A systematic review.
Q38317473Whole genome sequencing: a new paradigm in the surveillance and control of human tuberculosis
Q37833994Whole-Genome Enrichment Using RNA Probes and Sequencing of Chlamydia trachomatis Directly from Clinical Samples
Q28553483Whole-Genome Sequencing Analysis of Serially Isolated Multi-Drug and Extensively Drug Resistant Mycobacterium tuberculosis from Thai Patients
Q37611856Whole-Genome Sequencing of Mycobacterium tuberculosis Provides Insight into the Evolution and Genetic Composition of Drug-Resistant Tuberculosis in Belarus.
Q36084640Whole-genome sequencing for prediction of Mycobacterium tuberculosis drug susceptibility and resistance: a retrospective cohort study
Q41677504Whole-genome sequencing illuminates the evolution and spread of multidrug-resistant tuberculosis in Southwest Nigeria.
Q37229528Whole-genome sequencing of multidrug-resistant Mycobacterium tuberculosis isolates from Myanmar
Q34142073Whole-genome sequencing to control antimicrobial resistance
Q36333485Within patient microevolution of Mycobacterium tuberculosis correlates with heterogeneous responses to treatment

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