SAMHD1 restricts herpes simplex virus 1 in macrophages by limiting DNA replication.

scientific article published on 25 September 2013

SAMHD1 restricts herpes simplex virus 1 in macrophages by limiting DNA replication. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/JVI.02291-13
P932PMC publication ID3838123
P698PubMed publication ID24067963

P50authorAlberto Brandariz-NuñezQ39065841
P2093author name stringMatthew D Weitzman
Felipe Diaz-Griffero
Eui Tae Kim
Tommy E White
P2860cites workSAMHD1-deficient CD14+ cells from individuals with Aicardi-Goutières syndrome are highly susceptible to HIV-1 infectionQ21089603
Viperin (cig5), an IFN-inducible antiviral protein directly induced by human cytomegalovirusQ24292060
IFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi Sarcoma-associated herpesvirus infectionQ24302985
Genetic editing of herpes simplex virus 1 and Epstein-Barr herpesvirus genomes by human APOBEC3 cytidine deaminases in culture and in vivoQ24305160
SAMHD1 is a nucleic-acid binding protein that is mislocalized due to aicardi-goutières syndrome-associated mutationsQ24310328
Mutations involved in Aicardi-Goutières syndrome implicate SAMHD1 as regulator of the innate immune responseQ24338296
The restriction factors of human immunodeficiency virusQ24605108
How SAMHD1 changes our view of viral restrictionQ24605899
SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by VpxQ24605940
SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphatesQ24624362
A diverse range of gene products are effectors of the type I interferon antiviral responseQ24626018
Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 proteinQ24635842
Macrophages and cytokines in the early defence against herpes simplex virusQ24815062
HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolaseQ27675416
Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif proteinQ27860488
Intrinsic cellular defenses against human immunodeficiency virusesQ28659575
Tetherin inhibits retrovirus release and is antagonized by HIV-1 VpuQ29547836
Immune evasion and counteraction of restriction factors by HIV-1 and other primate lentivirusesQ30391530
SAMHD1 restricts HIV-1 infection in resting CD4(+) T cells.Q30421200
The RING-CH ligase K5 antagonizes restriction of KSHV and HIV-1 particle release by mediating ubiquitin-dependent endosomal degradation of tetherinQ33564429
The intrinsic antiviral defense to incoming HSV-1 genomes includes specific DNA repair proteins and is counteracted by the viral protein ICP0.Q33941037
Nuclear IFI16 induction of IRF-3 signaling during herpesviral infection and degradation of IFI16 by the viral ICP0 proteinQ34303188
Contribution of SAM and HD domains to retroviral restriction mediated by human SAMHD1.Q34312205
Nuclease activity of the human SAMHD1 protein implicated in the Aicardi-Goutieres syndrome and HIV-1 restriction.Q34325381
The retroviral restriction ability of SAMHD1, but not its deoxynucleotide triphosphohydrolase activity, is regulated by phosphorylationQ34340339
Intrinsic immunity: a front-line defense against viral attackQ34360874
Host factor SAMHD1 restricts DNA viruses in non-dividing myeloid cellsQ34795512
Human immunodeficiency virus type 1 modified to package Simian immunodeficiency virus Vpx efficiently infects macrophages and dendritic cellsQ35077587
Antiretroviral restriction factorsQ35686784
Human cytomegalovirus persistenceQ35899274
Tight interplay among SAMHD1 protein level, cellular dNTP levels, and HIV-1 proviral DNA synthesis kinetics in human primary monocyte-derived macrophagesQ36052320
Role of SAMHD1 nuclear localization in restriction of HIV-1 and SIVmacQ36136752
Herpes simplex viruses: mechanisms of DNA replicationQ36192926
Inactivating intracellular antiviral responses during adenovirus infectionQ36318156
Host restriction factors blocking retroviral replicationQ36687748
Restriction of diverse retroviruses by SAMHD1.Q36707281
Innate immune sensing of HIV-1 by dendritic cellsQ36748027
PML and PML nuclear bodies: implications in antiviral defenceQ36753891
Herpes Simplex Virus Type 1 infection: overview on relevant clinico-pathological featuresQ37058139
Intracellular nucleotide levels and the control of retroviral infectionsQ37244704
Intrinsic cellular defense mechanisms targeting human cytomegalovirusQ37799098
Role of promyelocytic leukemia protein in host antiviral defenseQ37825489
Control of HSV-1 latency in human trigeminal ganglia--current overviewQ37964558
Interplay between human cytomegalovirus and intrinsic/innate host responses: a complex bidirectional relationship.Q38018936
Restrictions to HIV-1 replication in resting CD4+ T lymphocytesQ38111619
Recent issues in herpes simplex encephalitisQ38115149
Phosphorylation of SAMHD1 by cyclin A2/CDK1 regulates its restriction activity toward HIV-1.Q39163475
The ability of primate lentiviruses to degrade the monocyte restriction factor SAMHD1 preceded the birth of the viral accessory protein Vpx.Q39405160
A truncated form of herpes simplex virus type 1 immediate-early protein Vmw110 is expressed in a cell type dependent mannerQ43961133
P433issue23
P407language of work or nameEnglishQ1860
P921main subjectmacrophageQ184204
P304page(s)12949-12956
P577publication date2013-09-25
P1433published inJournal of VirologyQ1251128
P1476titleSAMHD1 restricts herpes simplex virus 1 in macrophages by limiting DNA replication
P478volume87