Ang II and Ang IV: unraveling the mechanism of action on synaptic plasticity, memory, and epilepsy

scientific article published on January 2008

Ang II and Ang IV: unraveling the mechanism of action on synaptic plasticity, memory, and epilepsy is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1111/J.1755-5949.2008.00057.X
P932PMC publication ID6494056
P698PubMed publication ID19040556

P50authorIlse SmoldersQ72992945
Dimitri De BundelQ56863107
P2093author name stringYvette Michotte
Patrick Vanderheyden
P2860cites workA synaptic model of memory: long-term potentiation in the hippocampusQ22337276
Purification, characterization, and cloning of a cytosolic aspartyl aminopeptidaseQ24308332
GLUT-1 deficiency syndrome caused by haploinsufficiency of the blood-brain barrier hexose carrierQ24309065
Human placental leucine aminopeptidase/oxytocinase. A new member of type II membrane-spanning zinc metallopeptidase familyQ24315214
Long-lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant pathQ24538964
Pathology and pathophysiology of the amygdala in epileptogenesis and epilepsyQ24650174
Expression of placental leucine aminopeptidase/oxytocinase in neuronal cells and its action on neuronal peptidesQ28199101
The V1a vasopressin receptor is necessary and sufficient for normal social recognition: a gene replacement studyQ28267455
2-Deoxy-D-glucose reduces epilepsy progression by NRSF-CtBP-dependent metabolic regulation of chromatin structureQ28268494
Role of hippocampal Cav1.2 Ca2+ channels in NMDA receptor-independent synaptic plasticity and spatial memoryQ28511894
Cloning and characterization of a novel insulin-regulated membrane aminopeptidase from Glut4 vesiclesQ28569814
Involvement of the somatostatin-2 receptor in the anti-convulsant effect of angiotensin IV against pilocarpine-induced limbic seizures in ratsQ28570454
Involvement of D1 dopamine receptors in the cognitive effects of angiotensin IV and des-Phe6 angiotensin IVQ28573288
Spatial memory formation and memory-enhancing effect of glucose involves activation of the tuberous sclerosis complex-Mammalian target of rapamycin pathwayQ28575179
Distribution and cellular localization of insulin-regulated aminopeptidase in the rat central nervous systemQ28579048
The effects of angiotensin IV analogs on long-term potentiation within the CA1 region of the hippocampus in vitroQ28579223
Signaling by hepatocyte growth factor in neurons is induced by pharmacological stimulation of synaptic activityQ28583624
Learning induces long-term potentiation in the hippocampusQ29619482
Decreases in rat extracellular hippocampal glucose concentration associated with cognitive demand during a spatial taskQ30305450
Vasopressin is a physiological substrate for the insulin-regulated aminopeptidase IRAP.Q30444206
Hippocampal acetylcholine release during memory testing in rats: augmentation by glucoseQ30453913
Protective effect of anti-hypertensive treatment on cognitive function in essential hypertension: analysis of published clinical dataQ30744678
Characterization of a recombinant soluble form of human placental leucine aminopeptidase/oxytocinase expressed in Chinese hamster ovary cellsQ30827800
Characterization and signaling of the AT(4) receptor in human proximal tubule epithelial (HK-2) cellsQ31961569
Distribution of angiotensin IV binding sites (AT4 receptor) in the human forebrain, midbrain and pons as visualised by in vitro receptor autoradiography.Q32025740
Role of nitric oxide in angiotensin IV-induced increases in cerebral blood flowQ32036552
Therapeutic targeting of insulin-regulated aminopeptidase: heads and tails?Q33300628
Role of vasopressin in learning and memory in the hippocampusQ33540677
Brain somatostatin: a candidate inhibitory role in seizures and epileptogenesis.Q33785713
Angiotensin IV stimulates plasminogen activator inhibitor-1 expression in proximal tubular epithelial cellsQ33869866
A rapamycin-sensitive signaling pathway contributes to long-term synaptic plasticity in the hippocampusQ33898132
Neuromodulation of memory in the hippocampus by vasopressinQ34060981
The human hippocampus and spatial and episodic memoryQ34145961
The brain renin-angiotensin system: location and physiological roles.Q34188368
Angiotensin III: a central regulator of vasopressin release and blood pressure.Q34214360
The angiotensin IV/AT4 receptor.Q34368921
AT4 receptor activation increases intracellular calcium influx and induces a non-N-methyl-D-aspartate dependent form of long-term potentiation.Q34475220
Hypertension and angiotensin II hypersensitivity in aminopeptidase A-deficient mice.Q34520314
Fear conditioning occludes LTP-induced presynaptic enhancement of synaptic transmission in the cortical pathway to the lateral amygdalaQ34522595
Long-term potentiation in the amygdala: a cellular mechanism of fear learning and memoryQ34558801
A double leucine within the GLUT4 glucose transporter COOH-terminal domain functions as an endocytosis signalQ72196778
Further evidence for the interactions between angiotensin II and GABAergic transmission in pentylenetetrazol kindling seizures in miceQ72227279
AT4 receptor binding characteristics: D-amino acid- and glycine-substituted peptidesQ72714925
The major protein of GLUT4-containing vesicles, gp160, has aminopeptidase activityQ72863799
Elucidation of a specific binding site for angiotensin II(3-8), angiotensin IV, in mammalian heart membranesQ72888964
Central angiotensin IV binding sites: distribution and specificity in guinea pig brainQ72922615
Structure-binding studies of the adrenal AT4 receptor: analysis of position two- and three-modified angiotensin IV analogsQ73034958
Behavioural activity of angiotensin II (3-7)4Phe--analogue of natural fragment 3-7 of angiotensin IIQ73040034
Drug-induced changes in cerebral glucose consumption in bifrontal epilepsyQ73766333
Aminopeptidase N/CD13 is directly linked to signal transduction pathways in monocytesQ73777327
Important role for angiotensin III and IV in the brain renin-angiotensin systemQ73881047
Location of renin-angiotensin system components in the hypoglossal nucleus of the ratQ74338116
Characterization of AT4 receptor from bovine aortic endothelium with photosensitive analogues of angiotensin IVQ74378067
Differential kinetics of circulating angiotensin IV and II after treatment with angiotensin II type 1 receptor antagonist and their plasma levels in patients with chronic renal failureQ74590081
Characterization of angiotensin IV-degrading enzymes and receptors on rat mesangial cellsQ77355294
Structural analysis of angiotensin IV receptor (AT4) from selected bovine tissuesQ77362773
Characterization and purification of the bovine adrenal angiotensin IV receptor (AT4) using [125I]benzoylphenylalanine-angiotensin IV as a specific photolabelQ77387940
Adenosine-angiotensin II interactions in pentylenetetrazol seizure threshold in miceQ77982381
Combination of non-hypotensive doses of valsartan and enalapril improves survival of spontaneously hypertensive rats with endothelial dysfunctionQ77985786
Ang II and Ang III modulate PTZ seizure threshold in non-stressed and stressed mice: possible involvement of noradrenergic mechanismQ79256729
Nano-LC-MS/MS for the monitoring of angiotensin IV in rat brain microdialysates: limitations and possibilitiesQ80771358
The brain as an endocrine target for Peptide hormonesQ81065665
Glial-specific ablation of angiotensinogen lowers arterial pressure in renin and angiotensinogen transgenic miceQ81084463
Synaptic mechanisms in the kindled epileptic focus: a speculative synthesisQ39440396
The central effects of the renin-angiotensin systemQ39633203
Sub-cellular localization of insulin-regulated membrane aminopeptidase, IRAP to vesicles in neuronsQ40132721
Involvement of insulin-regulated aminopeptidase and/or aminopeptidase N in the angiotensin IV-induced effect on dopamine release in the striatum of the rat.Q40196455
Conformational induction is the key process for activation of the AT1 receptorQ40341077
Location and secretion of brain angiotensinogenQ40465215
The angiotensin IV system: functional implicationsQ40537981
Hematopoietic differentiation antigens that are membrane-associated enzymes: cutting is the key!Q40711842
Evidence that the angiotensin IV (AT(4)) receptor is the enzyme insulin-regulated aminopeptidase.Q40768845
Characterization of the AT(4) receptor in a human neuroblastoma cell line (SK-N-MC).Q40819711
Characterization and function of the bovine kidney epithelial angiotensin receptor subtype 4 using angiotensin IV and divalinal angiotensin IV as receptor ligandsQ40917544
Amygdala role in conditioned associative learningQ40929772
A globin fragment, LVV-hemorphin-7, induces [3H]thymidine incorporation in a neuronal cell line via the AT4 receptorQ40945054
Brain angiotensin receptor subtypes AT1, AT2, and AT4 and their functionsQ40955661
Enhanced angiotensin converting enzyme binding in arteries from spontaneously hypertensive ratsQ41087594
Behavioral consequences of intracerebral vasopressin and oxytocin: focus on learning and memoryQ41176049
Angiotensin IV receptors and signaling in opossum kidney cellsQ41279017
Quantification of renin mRNA in various mouse tissues by a novel solution hybridization assayQ41284468
Expression of the renin gene in extra-renal tissues of the rat.Q42164047
Angiotensin and renin in rat and dog brainQ42257445
Immunocytochemical localization of the insulin-responsive glucose transporter 4 (Glut4) in the rat central nervous system.Q42461232
Mitogen-activated protein kinase upregulates the dendritic translation machinery in long-term potentiation by controlling the mammalian target of rapamycin pathwayQ42513430
Characterization of the insulin-regulated membrane aminopeptidase in 3T3-L1 adipocytesQ42517117
Participation of angiotensin II in learning and memory. I. Interaction of angiotensin II with saralasinQ48463004
Identification of an AII(3-8) [AIV] binding site in guinea pig hippocampus.Q48467453
Membrane Localization of Endopeptidase‐24.11 and Peptidyl Dipeptidase A (Angiotensin Converting Enzyme) in the Pig Brain: A Study Using Subcellular Fractionation and Electron Microscopic ImmunocytochemistryQ48478626
Angiotensin II blocks hippocampal long-term potentiationQ48608093
Excitatory action of angiotensins II and IV on hippocampal neuronal activity in urethane anesthetized ratsQ48682751
The globin fragment LVV-hemorphin-7 is an endogenous ligand for the AT4 receptor in the brainQ48701785
The long and winding road to memory consolidationQ48723995
Intrahippocampal injections of somatostatin dissociate acquisition from the flexible use of place responsesQ48794686
The effect of angiotensin II and its fragments on post-alcohol impairment of learning and memoryQ48822233
The effect on drinking of peptide precursors and of shorter chain peptide fragments of angiotensin II injected into the rat's diencephalonQ48833033
Drinking induced by injection of angiotensin into the rain of the rat.Q48900874
Angiotensin II-(3-8)-hexapeptide affects motor activity, performance of passive avoidance and a conditioned avoidance response in ratsQ48934009
Distribution of AT4 receptors in the Macaca fascicularis brainQ49055335
Behavioral effects of angiotensin II microinjected into CA1 hippocampal area.Q51105897
Effects of the selective angiotensin II receptor antagonists losartan and PD123177 in animal models of anxiety and memory.Q51112004
Interactions between angiotensin II, diazepam, clonazepam and di-n-propylacetate in pentylenetetrazol kindling seizures in mice.Q51714736
Interactions between angiotensin II, GABA and diazepam in convulsive seizures.Q51809554
Effect of chronic angiotensin converting enzyme inhibition on spatial memory and anxiety-like behaviours in rats.Q51978955
Cognitive effects attributed to angiotensin II may result from its conversion to angiotensin IV.Q52002341
Identification of angiotensin IV binding sites in the mouse brain by a fluorescent binding study.Q52023364
Lateralized learning and memory effects of angiotensin II microinjected into the rat CA1 hippocampal area.Q52027260
Dynorphin A-(1-13) and (2-13) improve beta-amyloid peptide-induced amnesia in mice.Q52028333
Long-term inhibition of renin-angiotensin system sustains memory function in aged Dahl rats.Q52032035
Losartan improves the performance of ethanol-intoxicated rats in an eight-arm radial maze.Q52041633
CGP 42112A abolishes facilitation of recognition caused by angiotensin II and angiotensin II(3-7) in rats.Q52044669
Losartan influences behavioural effects of angiotensin II in rats.Q52046502
Effects of LY231617 and angiotensin IV on ischemia-induced deficits in circular water maze and passive avoidance performance in rats.Q52048507
Somatostatin alleviates impairment of working memory induced by hippocampal muscarinic M1 receptor blockade in rats.Q52055540
Attenuation of scopolamine-induced spatial memory deficits in the rat by cholinomimetic and non-cholinomimetic drugs using a novel task in the 12-arm radial maze.Q52068549
Interactions between angiotensin II and baclofen in shuttle-box and passive avoidance performance.Q52121193
Effect of angiotensin II and saralasin on motor activity and the passive avoidance behavior of ratsQ52123912
Attenuation of scopolamine-induced spatial learning impairments by an angiotensin IV analog.Q52185174
The contribution of AT1 and AT2 angiotensin receptors to its cognitive effects.Q52203718
Impaired retention by angiotensin II mediated by the AT1 receptor.Q52211161
Effect of angiotensin II and vasopressin on acquisition and extinction of conditioned avoidance in rats.Q52217759
Dopaminergic influence on the effects of angiotensin II in behavioural reactions.Q52270882
ACE inhibitors and the kidney.Q53773106
Angiotensin IV Activates the Nuclear Transcription Factor-κB and Related Proinflammatory Genes in Vascular Smooth Muscle CellsQ61854944
Adaptive changes in the effects of angiotensin II on the convulsive-seizure threshold in cases of altered sensitivity of dopamine receptorsQ68455462
Angiotensin II in the hippocampus. A histochemical and electrophysiological studyQ70681508
Dose and time dependency of angiotensin II inhibition of hippocampal long-term potentiationQ70813999
The carboxyl terminus of GLUT4 contains a serine-leucine-leucine sequence that functions as a potent internalization motif in Chinese hamster ovary cellsQ71246222
Angiotensin II blockade of long-term potentiation at the perforant path--granule cell synapse in vitroQ71524337
Autoradiographic identification of brain angiotensin IV binding sites and differential c-Fos expression following intracerebroventricular injection of angiotensin II and IV in ratsQ71725922
Effects of non-peptide angiotensin II-receptor antagonists on pentylenetetrazol kindling in miceQ71788061
Angiotensin III and IV activation of the brain AT1 receptor subtype in cardiovascular functionQ71911932
AT4 receptor structure-binding relationship: N-terminal-modified angiotensin IV analoguesQ72120113
GLUT1 deficiency syndrome--2007 updateQ34667235
Neuronal apoptosis after brief and prolonged seizures.Q34763745
Functional and morphological changes in the hippocampal neuronal circuits associated with epileptic seizuresQ34970027
On the Role of Somatostatin in Seizure Control: Clues from the HippocampusQ35545445
Resistance to excitotoxin-induced seizures and neuronal death in mice lacking the preprotachykinin A geneQ35733687
Brain angiotensin II and synaptic transmissionQ35883454
Oxytocin, vasopressin, and social recognition in mammalsQ35890733
Angiotensin peptides modulatory system: how is it implicated in the control of seizure susceptibility?Q35988212
Endogenous dynorphins inhibit excitatory neurotransmission and block LTP induction in the hippocampus.Q36174208
Parahippocampal networks, intractability, and the chronic epilepsy of kindling.Q36355836
Wide distribution of immunoreactive renin in nerve cells of human brainQ36407017
The role of postsynaptic calcium in the induction of long-term potentiationQ36472942
Aminopeptidase A inhibitors as potential central antihypertensive agentsQ36675846
Angiotensin IV Reverses the Acute Cerebral Blood Flow Reduction after Experimental Subarachnoid Hemorrhage in the RatQ36676246
Serotonin and epilepsyQ36703063
Electrical stimulation protocols for hippocampal synaptic plasticity and neuronal hyper-excitability: are they effective or relevant?Q36720349
Adenosine-based cell therapy approaches for pharmacoresistant epilepsies.Q36788952
Enzymatic pathways of the brain renin-angiotensin system: unsolved problems and continuing challenges.Q36817565
Characterization of the binding properties and physiological action of divalinal-angiotensin IV, a putative AT4 receptor antagonistQ36837133
Angiotensin II- and IV-induced changes in cerebral blood flow. Roles of AT1, AT2, and AT4 receptor subtypesQ36854986
Neuropsychological correlates of hypertension: review and methodologic considerationsQ36858700
Epileptogenesis in the dentate gyrus: a critical perspectiveQ36926926
Toward an integrative perspective on hippocampal function: from the rapid encoding of experience to adaptive behaviorQ37003959
The basic science of memory as it applies to epilepsyQ37019193
Angiotensin receptor subtype mediated physiologies and behaviors: new discoveries and clinical targetsQ37045324
Brain angiotensin receptors and binding proteinsQ37049094
The significance of brain aminopeptidases in the regulation of the actions of angiotensin peptides in the brainQ37054961
Somatostatin: an endogenous antiepilepticQ37067748
Characterization of the TPR-MET oncogene p65 and the MET protooncogene p140 protein-tyrosine kinasesQ37479257
Captopril and enalapril improve cognition and depressed mood in hypertensive patients.Q38421469
Effect of I.C.V. injection of AT4 receptor ligands, NLE1-angiotensin IV and LVV-hemorphin 7, on spatial learning in rats.Q38450522
The cytoplasmic tail of the T cell receptor zeta chain is required for signaling via CD26.Q39255555
Long-lasting enhancement of synaptic excitability of CA1/subiculum neurons of the rat ventral hippocampus by vasopressin and vasopressin(4-8).Q39436110
Trandolapril attenuates acquisition of conditioned avoidance in rats.Q42636579
AT(2) but not AT(1) receptor antagonism abolishes angiotensin II increase of the acquisition of conditioned avoidance responses in rats.Q42669920
The amino terminus of insulin-responsive aminopeptidase causes Glut4 translocation in 3T3-L1 adipocytesQ42795999
Insulin stimulates cell surface aminopeptidase activity toward vasopressin in adipocytesQ42802101
Characterization of the insulin-regulated endocytic recycling mechanism in 3T3-L1 adipocytes using a novel reporter moleculeQ42805489
Potentiation of cholinergic transmission in the rat hippocampus by angiotensin IV and LVV-hemorphin-7.Q43543037
Comparative studies on the memory-enhancing actions of captopril and losartan in mice using inhibitory shock avoidance paradigmQ43602969
Interaction between angiotensin IV and adenosine A(1) receptor related drugs in passive avoidance conditioning in ratsQ43620962
AT1 receptor antagonist telmisartan administered peripherally inhibits central responses to angiotensin II in conscious rats.Q43641852
Angiotensin IV enhances LTP in rat dentate gyrus in vivoQ43713596
Effects of angiotensin III and angiotensin IV on pentylenetetrazol seizure susceptibility (threshold and kindling): interaction with adenosine A(1) receptorsQ43796454
A role for the angiotensin AT4 receptor subtype in overcoming scopolamine-induced spatial memory deficitsQ43814000
Interaction of angiotensin II and III with adenosine A(1) receptor-related drugs in passive avoidance conditioning in ratsQ43865380
Heightened seizure severity in somatostatin knockout miceQ43873850
Angiotensin IV is a potent agonist for constitutive active human AT1 receptors. Distinct roles of the N-and C-terminal residues of angiotensin II during AT1 receptor activationQ43990144
Tonin expression in the rat brain and tonin-mediated central production of angiotensin II.Q44014470
Oxytocin induces long-term depression on the rat dentate gyrus: possible ATPase and ectoprotein kinase mediationQ44070619
Role of AT2 receptor in the brain in regulation of blood pressure and water intakeQ44185525
Expression of insulin-responsive glucose transporter GLUT4 mRNA in the rat brain and spinal cord: an in situ hybridization studyQ44198241
Genetic disruption of cortical interneuron development causes region- and GABA cell type-specific deficits, epilepsy, and behavioral dysfunction.Q44281916
Effects of arginine-vasopressin (AVP) on long-term potentiation in intact anesthetized ratsQ44308093
The effects of sarmesin, an Angiotensin II analogue on seizure susceptibility, memory retention and nociceptionQ44332885
Endogenous dynorphin in epileptogenesis and epilepsy: anticonvulsant net effect via kappa opioid receptorsQ44334254
Hippocampal dynorphin B injections impair spatial learning in rats: a kappa-opioid receptor-mediated effectQ44349020
The renin-angiotensin system is upregulated in the cortex and hippocampus of patients with temporal lobe epilepsy related to mesial temporal sclerosis.Q44361362
Inhibition of L-type voltage dependent calcium channels causes impairment of long-term potentiation in the hippocampal CA1 region in vivoQ44371592
Ethanol-induced suppression of LTP can be attenuated with an angiotensin IV analogQ44397760
Discovery of a distinct binding site for angiotensin II (3-8), a putative angiotensin IV receptorQ44413571
The Study on Cognition and Prognosis in the Elderly (SCOPE): principal results of a randomized double-blind intervention trialQ44417511
Effects of angiotensin II and its receptor antagonists on motor activity and anxiety in ratsQ44495613
Angiotensin AT4 ligands are potent, competitive inhibitors of insulin regulated aminopeptidase (IRAP).Q44518988
Perindopril pROtection aGainst REcurrent Stroke Study (PROGRESS): interpretation and implementation.Q44550250
Effect of angiotensin IV on the acquisition of the water maze task and ryanodine channel function.Q44588430
Influence of losartan and atenolol on memory function in very elderly hypertensive patientsQ44632352
Activation of long-term synaptic plasticity causes suppression of epileptiform activity in rat hippocampal slicesQ44730127
Effects of valsartan compared with enalapril on blood pressure and cognitive function in elderly patients with essential hypertensionQ44745545
Epilepsy duration, febrile seizures, and cerebral glucose metabolismQ44792016
Norleucine1-Angiotensin IV alleviates mecamylamine-induced spatial memory deficitsQ44828738
Chronic production of angiotensin IV in the brain leads to hypertension that is reversible with an angiotensin II AT1 receptor antagonistQ44875167
Anticonvulsant action of hippocampal dopamine and serotonin is independently mediated by D and 5-HT receptorsQ44893909
Attenuation of scopolamine-induced learning deficits by LVV-hemorphin-7 in rats in the passive avoidance and water maze paradigmsQ45012094
Metabolism of angiotensin II is required for its in vivo effect on dopamine release in the striatum of the rat.Q45018901
Hepatocyte growth factor improved learning and memory dysfunction of microsphere-embolized ratsQ45076516
Hepatocyte growth factor as an enhancer of nmda currents and synaptic plasticity in the hippocampusQ45079676
Down-regulation of dopamine D1 and D2 receptors in the basal ganglia of PTZ kindling model of epilepsy: effects of angiotensin IV.Q45080789
Differential modulation of baroreflex control of heart rate by neuron- vs. glia-derived angiotensin II.Q45092023
Angiotensin II blocks memory consolidation through an AT2 receptor-dependent mechanism.Q45155033
The enhancing effects of hippocampal infusions of glucose are not restricted to spatial working memoryQ45275001
Alleviation of Abeta-induced cognitive impairment by ultrasound-mediated gene transfer of HGF in a mouse modelQ45875353
Candesartan and cognitive decline in older patients with hypertension: a substudy of the SCOPE trial.Q46204112
Effect of losartan and enalapril on cognitive deficit caused by Goldblatt induced hypertension.Q46426608
In vivo modulatory action of extracellular glutamate on the anticonvulsant effects of hippocampal dopamine and serotoninQ46536791
Secretory vesicle aminopeptidase B related to neuropeptide processing: molecular identification and subcellular localization to enkephalin- and NPY-containing chromaffin granulesQ46537906
Somatostatin depresses long-term potentiation and Ca2+ signaling in mouse dentate gyrusQ46549980
Brain and peripheral angiotensin II type 1 receptors mediate renal vasoconstrictor and blood pressure responses to angiotensin IV in the rat.Q46656502
Induction and maintenance of late-phase long-term potentiation in isolated dendrites of rat hippocampal CA1 pyramidal neuronesQ46658286
Direct enhancement of hippocampal dopamine or serotonin levels as a pharmacodynamic measure of combined antidepressant-anticonvulsant action.Q46672872
Effect of D(3) dopamine receptors blockade on the cognitive effects of angiotensin IV in rats.Q46688100
Glutamatergic regulation of the p70S6 kinase in primary mouse neuronsQ46720415
Disruption of interneuron developmentQ46733519
Valsartan abolishes most of the memory-improving effects of intracerebroventricular angiotensin II in rats.Q46816577
Effect of telmisartan/hydrochlorothiazide vs lisinopril/hydrochlorothiazide combination on ambulatory blood pressure and cognitive function in elderly hypertensive patientsQ46819242
Dynorphin A (2-13) improves mecamylamine-induced learning impairment accompanied by reversal of reductions in acetylcholine release in ratsQ46824669
Angiotensin IV enhances phosphorylation of 4EBP1 by multiple signaling events in lung endothelial cellsQ46846204
Evidence supporting a functional role for intracellular renin in the brainQ46919174
CCKB-receptor activation augments the long-term potentiation in guinea pig hippocampal slicesQ46966538
Intracerebroventricular effects of angiotensin II on a step-through passive avoidance task in rats.Q47326003
Hepatocyte growth factor attenuates cerebral ischemia-induced learning dysfunctionQ47351828
Localization of components of the renin-angiotensin system in the suprachiasmatic nucleus of normotensive Sprague-Dawley rats: part B. angiotensin II (AT1)-receptors, a light and electron microscopic studyQ47598998
Localization of components of the renin-angiotensin system in the suprachiasmatic nucleus of normotensive Sprague-Dawley rats: part A. angiotensin I/II, a light and electron microscopic studyQ47599012
Angiotensin II inhibits long-term potentiation within the lateral nucleus of the amygdala through AT1 receptorsQ47698919
Involvement of dopamine receptors in beneficial effects of tachykinins on scopolamine-induced impairment of alternation performance in miceQ47771462
V1a receptor knockout mice exhibit impairment of spatial memory in an eight-arm radial mazeQ47907446
Inhibition by [Arg8]-vasopressin of long term potentiation in guinea pig hippocampal sliceQ47931436
Cholecystokinin (CCK-8S) prolongs 'unsaturated' theta-pulse induced long-term potentiation in rat hippocampal CA1 in vitroQ48115959
The 140-kDa protein of blood-brain barrier-associated pericytes is identical to aminopeptidase N.Q48118260
Hepatocyte growth factor-induced enhancement of dendritic branching is blocked by inhibitors of N-methyl-D-aspartate receptors and calcium/calmodulin-dependent kinasesQ48122008
Localization of renin expressing cells in the brain, by use of a REN-eGFP transgenic modelQ48140732
Central pressor actions of aminopeptidase-resistant angiotensin II analogs: challenging the angiotensin III hypothesisQ48182833
PC18, a specific aminopeptidase N inhibitor, induces vasopressin release by increasing the half-life of brain angiotensin III.Q48199745
Psychotropic effects of angiotensin II and III in rats: locomotor and exploratory vs cognitive behaviourQ48208370
Contributions of the brain angiotensin IV-AT4 receptor subtype system to spatial learningQ48218315
Angiotensin AII AT1 receptor mediates ethanol-diazepam inhibition of hippocampal LTP.Q48228448
Learning and anxiety in angiotensin-deficient miceQ48231386
Use of a structural analogue versus a stable isotope labeled internal standard for the quantification of angiotensin IV in rat brain dialysates using nano-liquid chromatography/tandem mass spectrometryQ48258707
Role of angiotensin II and AT1 receptors in hippocampal LTP.Q48276912
Angiotensin II suppresses long-term depression in the lateral amygdala of mice via L-type calcium channelsQ48278805
Opposite effects of angiotensin II and IV in the lateral nucleus of the amygdalaQ48306989
An examination of the relations between hippocampal long-term potentiation, kindling, afterdischarge, and place learning in the water mazeQ48314345
Localization of immunoreactive glutamyl aminopeptidase in rat brain. II. Distribution and correlation with angiotensin II.Q48318272
Localization of immunoreactive glutamyl aminopeptidase in rat brain. I. Association with cerebral microvesselsQ48318283
In vitro effect of angiotensin II on GABA release in rat hippocampusQ48333660
Conservation of total synaptic weight through balanced synaptic depression and potentiationQ48346111
Participation of angiotensin II in learning and memory. II. Interactions of angiotensin II with dopaminergic drugsQ48358655
High-performance liquid chromatographic analysis of 'specifically bound' label after [125I]angiotensin II binding to rat brain membranesQ48364722
Angiotensin II(3-8) (ANG IV) hippocampal binding: potential role in the facilitation of memoryQ48381985
Oxytocin improves long-lasting spatial memory during motherhood through MAP kinase cascadeQ48382169
Differential behavioral effects of angiotensin II microinjected unilaterally into the CA1 hippocampal areaQ48407930
Angiotensin II disrupts inhibitory avoidance memory retrievalQ48447208
D2 dopamine receptor blockade prevents cognitive effects of Ang IV and des-Phe6 Ang IV.Q48447385
P433issue4
P921main subjectsynaptic plasticityQ1551556
P304page(s)315-339
P577publication date2008-01-01
P1433published inCNS Neuroscience & TherapeuticsQ5013184
P1476titleAng II and Ang IV: unraveling the mechanism of action on synaptic plasticity, memory, and epilepsy
P478volume14

Reverse relations

cites work (P2860)
Q36098738AGTR1 gene variation: association with depression and frontotemporal morphology
Q49721288Brain Renin-Angiotensin System Blockade Attenuates Methamphetamine-Induced Hyperlocomotion and Neurotoxicity
Q37091405Central administration of angiotensin IV rapidly enhances novel object recognition among mice
Q38461657Cerebroprotective effects of RAS inhibitors: Beyond their cardio-renal actions.
Q34543485Discovery of inhibitors of insulin-regulated aminopeptidase as cognitive enhancers.
Q46799226Enalapril enhances the anticonvulsant activity of lamotrigine in the test of maximal electroshock
Q94353827Erratum
Q30530935Evaluation of metabolically stabilized angiotensin IV analogs as procognitive/antidementia agents
Q24635261Facilitation of hippocampal synaptogenesis and spatial memory by C-terminal truncated Nle1-angiotensin IV analogs
Q36415423Importance of the brain Angiotensin system in Parkinson's disease
Q36241932International Union of Basic and Clinical Pharmacology. XCIX. Angiotensin Receptors: Interpreters of Pathophysiological Angiotensinergic Stimuli [corrected].
Q34413859Neuropeptides as targets for the development of anticonvulsant drugs.
Q38217456Neuropeptides: metabolism to bioactive fragments and the pharmacology of their receptors
Q46322831Physiological and pathophysiological functions of different angiotensins in the brain
Q46316918Renin-angiotensin system as a potential target for new therapeutic approaches in Parkinson's disease
Q64274255Role of the Angiotensin Pathway and its Target Therapy in Epilepsy Management
Q36520049The Angiotensin II Type 2 Receptor in Brain Functions: An Update
Q38005611The brain renin-angiotensin system: a diversity of functions and implications for CNS diseases
Q50679867The effects of valsartan on cognitive deficits induced by aluminum trichloride and d-galactose in mice.
Q35928365The role of insulin-regulated aminopeptidase in MHC class I antigen presentation

Search more.