| scholarly article | Q13442814 |
| P356 | DOI | 10.2217/14622416.9.12.1917 |
| P698 | PubMed publication ID | 19072648 |
| P50 | author | Kohzoh Imai | Q11376649 |
| Minoru Toyota | Q11634024 | ||
| Hiromu Suzuki | Q88076551 | ||
| Yasuhisa Shinomura | Q113985398 | ||
| P2093 | author name string | Takashi Tokino | |
| P2860 | cites work | Phase I and pharmacodynamic trial of the DNA methyltransferase inhibitor decitabine and carboplatin in solid tumors | Q46958949 |
| Expression of the cell death genes BNip3 and NIX in ductal carcinoma in situ of the breast; correlation of BNip3 levels with necrosis and grade | Q47348582 | ||
| Intratumoral hypoxia, radiation resistance, and HIF-1. | Q47601594 | ||
| Distinct methylation patterns of two APC gene promoters in normal and cancerous gastric epithelia | Q47835975 | ||
| Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: miR-34a is a p53 target that induces apoptosis and G1-arrest | Q48078984 | ||
| Genetic and epigenetic profiling in early colorectal tumors and prediction of invasive potential in pT1 (early invasive) colorectal cancers. | Q53338659 | ||
| Targeting polo-like kinase 1 for cancer therapy | Q53348000 | ||
| Alterations and hypermethylation of the p14(ARF) gene in gastric cancer | Q53407245 | ||
| Suppressing cancer: the importance of being senescent | Q53663083 | ||
| RAS oncogenes: the first 30 years. | Q55036584 | ||
| RAF/RAS oncogenes and mismatch-repair status | Q57281056 | ||
| Methylation of the CDH1 promoter as the second genetic hit in hereditary diffuse gastric cancer | Q57591268 | ||
| Epigenetic gene silencing in cancer – a mechanism for early oncogenic pathway addiction? | Q22251049 | ||
| Chfr defines a mitotic stress checkpoint that delays entry into metaphase | Q22254761 | ||
| Sox17 and Sox4 differentially regulate beta-catenin/T-cell factor activity and proliferation of colon carcinoma cells | Q24294207 | ||
| SFRP1 suppressed hepatoma cells growth through Wnt canonical signaling pathway | Q24303537 | ||
| Epigenetic inactivation of the canonical Wnt antagonist SRY-box containing gene 17 in colorectal cancer | Q24321845 | ||
| Comprehensive analysis of CpG islands in human chromosomes 21 and 22 | Q24531622 | ||
| RASSF2, a potential tumour suppressor, is silenced by CpG island hypermethylation in gastric cancer | Q24651245 | ||
| Epigenetic inactivation of CHFR in human tumors | Q24670147 | ||
| AURORA-A amplification overrides the mitotic spindle assembly checkpoint, inducing resistance to Taxol | Q27824792 | ||
| Worms gang up on bacteria | Q27860588 | ||
| Oncomirs - microRNAs with a role in cancer | Q27860773 | ||
| The consensus coding sequences of human breast and colorectal cancers | Q27861035 | ||
| The genomic landscapes of human breast and colorectal cancers | Q27861078 | ||
| Surfing the p53 network | Q28032484 | ||
| Lessons from hereditary colorectal cancer | Q28131788 | ||
| RASSF3 and NORE1: identification and cloning of two human homologues of the putative tumor suppressor gene RASSF1 | Q28215344 | ||
| Control of developmental regulators by Polycomb in human embryonic stem cells | Q28235841 | ||
| Tumor-suppressive miR-34a induces senescence-like growth arrest through modulation of the E2F pathway in human colon cancer cells | Q28249223 | ||
| Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer | Q28251800 | ||
| Cancer genes and the pathways they control | Q28275089 | ||
| 14-3-3sigma is a p53-regulated inhibitor of G2/M progression | Q28276061 | ||
| DKK1, a negative regulator of Wnt signaling, is a target of the beta-catenin/TCF pathway | Q28283034 | ||
| Epigenetic inactivation of the Wnt antagonist DICKKOPF-1 (DKK-1) gene in human colorectal cancer | Q28298475 | ||
| p53 mutations in human cancers | Q28302973 | ||
| A microRNA component of the p53 tumour suppressor network | Q28305330 | ||
| Dnmt3b promotes tumorigenesis in vivo by gene-specific de novo methylation and transcriptional silencing | Q28505145 | ||
| RASSF6 is a novel member of the RASSF family of tumor suppressors | Q28509722 | ||
| Chfr is required for tumor suppression and Aurora A regulation | Q28510913 | ||
| Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis | Q29547575 | ||
| Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions | Q29614512 | ||
| Morphogenetic roles of classic cadherins | Q29614941 | ||
| Secreted antagonists of the Wnt signalling pathway | Q29615521 | ||
| Cancer epigenomics: DNA methylomes and histone-modification maps | Q29615524 | ||
| WNT and beta-catenin signalling: diseases and therapies | Q29616159 | ||
| The history of cancer epigenetics | Q29617273 | ||
| A second canon. Functions and mechanisms of beta-catenin-independent Wnt signaling | Q29619294 | ||
| Convergence of Wnt, beta-catenin, and cadherin pathways | Q29619504 | ||
| Transcriptional activation of miR-34a contributes to p53-mediated apoptosis | Q29619556 | ||
| Epigenetic stem cell signature in cancer | Q29622897 | ||
| Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer | Q29622925 | ||
| Derepression in the desert: the third workshop on clinical translation of epigenetics in cancer therapeutics | Q30436156 | ||
| Epigenetic inactivation of a RAS association domain family protein from the lung tumour suppressor locus 3p21.3. | Q30884723 | ||
| A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing | Q33268624 | ||
| Comparing the DNA hypermethylome with gene mutations in human colorectal cancer | Q33300134 | ||
| Phase I study of epigenetic modulation with 5-azacytidine and valproic acid in patients with advanced cancers | Q33381378 | ||
| Silencing of the E-cadherin invasion-suppressor gene by CpG methylation in human carcinomas | Q34053843 | ||
| Chromosome segregation and cancer: cutting through the mystery | Q34119639 | ||
| A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer | Q34126908 | ||
| Physiological and pathological responses to hypoxia | Q34322819 | ||
| Silencing of the hypoxia-inducible cell death protein BNIP3 in pancreatic cancer | Q34338082 | ||
| Frequent epigenetic inactivation of Wnt inhibitory factor-1 in human gastrointestinal cancers. | Q34432769 | ||
| The Ras effector RASSF2 is a novel tumor-suppressor gene in human colorectal cancer | Q34433428 | ||
| Identification of RASSF8 as a candidate lung tumor suppressor gene | Q34492221 | ||
| The potential role of DFNA5, a hearing impairment gene, in p53-mediated cellular response to DNA damage | Q34555517 | ||
| APC, signal transduction and genetic instability in colorectal cancer | Q34568154 | ||
| E-cadherin germline mutations in familial gastric cancer. | Q34746744 | ||
| DNA hypomethylation leads to elevated mutation rates | Q34752442 | ||
| Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer. | Q34783833 | ||
| Secreted Frizzled-related proteins: searching for relationships and patterns | Q34811402 | ||
| Essential requirement for Wnt signaling in proliferation of adult small intestine and colon revealed by adenoviral expression of Dickkopf-1. | Q35122385 | ||
| Control of gut differentiation and intestinal-type gastric carcinogenesis | Q35190157 | ||
| Expression of the gene encoding the proapoptotic Nip3 protein is induced by hypoxia | Q35195197 | ||
| BRAF as a potential therapeutic target in melanoma and other malignancies | Q35212513 | ||
| High frequency of hypermethylation at the 14-3-3 sigma locus leads to gene silencing in breast cancer | Q35759154 | ||
| The role of hypoxia inducible factor 1 (HIF-1) in hypoxia induced apoptosis | Q35903445 | ||
| CpG island methylation in gastroenterologic neoplasia: a maturing field. | Q35936582 | ||
| Integrated genetic and epigenetic analysis identifies three different subclasses of colon cancer. | Q36276940 | ||
| Oncogene-induced cell senescence--halting on the road to cancer | Q36587198 | ||
| Function and biological roles of the Dickkopf family of Wnt modulators | Q36672665 | ||
| Promoter hypermethylation of the Chfr gene in neoplastic and non-neoplastic gastric epithelia | Q36694133 | ||
| DNA methylation as a therapeutic target in cancer | Q36760984 | ||
| Cytoplasmic RASSF2A is a proapoptotic mediator whose expression is epigenetically silenced in gastric cancer | Q36818078 | ||
| A microRNA DNA methylation signature for human cancer metastasis | Q36861111 | ||
| Mutations in both KRAS and BRAF may contribute to the methylator phenotype in colon cancer | Q36891683 | ||
| A functional genomics approach for the identification of putative tumor suppressor genes: Dickkopf-1 as suppressor of HeLa cell transformation | Q38349343 | ||
| Canonical Wnt signals are essential for homeostasis of the intestinal epithelium | Q39895829 | ||
| Frequent epigenetic inactivation of SFRP genes in hepatocellular carcinoma | Q39966635 | ||
| Exploration of tumor-suppressive microRNAs silenced by DNA hypermethylation in oral cancer | Q39996295 | ||
| The synergistic effect of 5-aza-2'-deoxycytidine and 5-fluorouracil on drug-resistant tumors | Q40095644 | ||
| Frequent epigenetic inactivation of DICKKOPF family genes in human gastrointestinal tumors. | Q40098270 | ||
| p53-mediated activation of miRNA34 candidate tumor-suppressor genes. | Q40102003 | ||
| Frequent epigenetic inactivation of SFRP genes and constitutive activation of Wnt signaling in gastric cancer | Q40171588 | ||
| Identification of DFNA5 as a target of epigenetic inactivation in gastric cancer | Q40212302 | ||
| Synergic antiproliferative effect of DNA methyltransferase inhibitor in combination with anticancer drugs in gastric carcinoma | Q40262211 | ||
| Promoter methylation of the secreted frizzled-related protein 1 gene SFRP1 is frequent in hepatocellular carcinoma | Q40263391 | ||
| The significance of aberrant CHFR methylation for clinical response to microtubule inhibitors in gastric cancer | Q40299123 | ||
| Upregulation of BNIP3 by 5-aza-2'-deoxycytidine sensitizes pancreatic cancer cells to hypoxia-mediated cell death. | Q40412450 | ||
| P14 methylation in human colon cancer is associated with microsatellite instability and wild-type p53. | Q40667147 | ||
| Frequent hypermethylation of CpG islands and loss of expression of the 14-3-3 sigma gene in human hepatocellular carcinoma | Q40842637 | ||
| Hypermethylation of the promoter region of the E-cadherin gene (CDH1) in sporadic and ulcerative colitis associated colorectal cancer | Q42114865 | ||
| Frequent and histological type-specific inactivation of 14-3-3sigma in human lung cancers | Q43955981 | ||
| Wnt inhibitory factor-1 is silenced by promoter hypermethylation in human lung cancer | Q44980772 | ||
| APC promoter hypermethylation contributes to the loss of APC expression in colorectal cancers with allelic loss on 5q. | Q46066378 | ||
| Small interfering RNA-induced CHFR silencing sensitizes oral squamous cell cancer cells to microtubule inhibitors. | Q46670390 | ||
| P433 | issue | 12 | |
| P921 | main subject | DNA methylation | Q874745 |
| P304 | page(s) | 1917-1928 | |
| P577 | publication date | 2008-12-01 | |
| P13046 | publication type of scholarly work | review article | Q7318358 |
| P1433 | published in | Pharmacogenomics | Q15724625 |
| P1476 | title | DNA methylation and cancer pathways in gastrointestinal tumors | |
| P478 | volume | 9 |
| Q33850782 | Aberrant methylation of microRNA-34b/c is a predictive marker of metachronous gastric cancer risk. |
| Q38373884 | Assessment of concordance between fresh-frozen and formalin-fixed paraffin embedded tumor DNA methylation using a targeted sequencing approach |
| Q47221741 | Colorectal cancer cells Caco-2 and HCT116 resist epigenetic effects of isothiocyanates and selenium in vitro |
| Q48214417 | DNA Methylation and the Potential Role of Methyl-Containing Nutrients in Cardiovascular Diseases. |
| Q26998741 | DNA methylation and microRNA dysregulation in cancer |
| Q38528438 | DNA methylation as a molecular biomarker in gastric cancer |
| Q38498718 | Differential DNA methylation status between human preadipocytes and mature adipocytes |
| Q37973293 | Emerging links between epigenetic alterations and dysregulation of noncoding RNAs in cancer |
| Q26771428 | Epigenetic associations in relation to cardiovascular prevention and therapeutics |
| Q36557481 | Epigenetic silencing of NTSR1 is associated with lateral and noninvasive growth of colorectal tumors. |
| Q38951927 | Epigenetic silencing of diacylglycerol kinase gamma in colorectal cancer |
| Q34084251 | Epigenetically regulated MIR941 and MIR1247 target gastric cancer cell growth and migration |
| Q35666522 | Genetic and Epigenetic Alterations in Barrett's Esophagus and Esophageal Adenocarcinoma |
| Q43630715 | Identification of gastric cancer risk markers that are informative in individuals with past H. pylori infection |
| Q38176848 | LncRNAs: new players in gliomas, with special emphasis on the interaction of lncRNAs With EZH2. |
| Q37620965 | Methods for genome-wide analysis of DNA methylation in intestinal tumors |
| Q39647946 | Methylation-associated silencing of microRNA-34b/c in gastric cancer and its involvement in an epigenetic field defect |
| Q35120258 | MiR-132 suppresses the migration and invasion of lung cancer cells via targeting the EMT regulator ZEB2. |
| Q38321676 | Novel target genes and a valid biomarker panel identified for cholangiocarcinoma |
| Q36222404 | On the epigenetics of vascular regulation and disease |
| Q36414391 | Oxidized low-density lipoprotein is a common risk factor for cardiovascular diseases and gastroenterological cancers via epigenomical regulation of microRNA-210 |
| Q34680636 | Plasma Triglyceride Levels May Be Modulated by Gene Expression of IQCJ, NXPH1, PHF17 and MYB in Humans |
| Q38018996 | Potential usefulness of DNA methylation as a risk marker for digestive cancer associated with inflammation |
| Q35609447 | Prognostic significance of aberrant gene methylation in gastric cancer |
| Q37832910 | Role of DNA methylation in the development of diffuse-type gastric cancer |
| Q54244033 | Role of hMLH1 and E-cadherin promoter methylation in gastric cancer progression |
| Q34776216 | The novel colorectal cancer biomarkers CDO1, ZSCAN18 and ZNF331 are frequently methylated across gastrointestinal cancers |
| Q50049729 | The zebrafish: A fintastic model for hematopoietic development and disease. |
| Q45946666 | Wnt antagonist DICKKOPF‐3 (Dkk‐3) induces apoptosis in human renal cell carcinoma |
| Q34769868 | miR-132/212 cluster inhibits the growth of lung cancer xenografts in nude mice. |
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