Role of NADPH oxidase-mediated reactive oxygen species in podocyte injury

scientific article

Role of NADPH oxidase-mediated reactive oxygen species in podocyte injury is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.1155/2013/839761
P932PMC publication ID3844218
P698PubMed publication ID24319690
P5875ResearchGate publication ID259250258

P2093author name stringChun Zhang
Shan Chen
Xian-Fang Meng
P2860cites workSelective albuminuria via podocyte albumin transport in puromycin nephrotic rats is attenuated by an inhibitor of NADPH oxidaseQ50436171
Podocyte as the target for aldosterone: roles of oxidative stress and Sgk1.Q51089166
Calcium entry via TRPC6 mediates albumin overload-induced endoplasmic reticulum stress and apoptosis in podocytes.Q52616889
Mesangial medium from IgA nephropathy patients induces podocyte epithelial-to-mesenchymal transition through activation of the phosphatidyl inositol-3-kinase/Akt signaling pathway.Q53167554
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NAD(P)H oxidase activity in cultured human podocytes: effects of adenosine triphosphateQ74326563
Oxidative stress and glomerular filtration barrier injury: role of the renin-angiotensin system in the Ren2 transgenic ratQ79760771
Glomerular epithelial cells transform to myofibroblasts: early but not late removal of TGF-beta1 reverses transformationQ80180555
Salt-induced nephropathy in obese spontaneously hypertensive rats via paradoxical activation of the mineralocorticoid receptor: role of oxidative stressQ81310501
NADPH oxidase-mediated upregulation of connexin43 contributes to podocyte injuryQ84603341
The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiologyQ27860991
Homocysteine enhances TIMP-1 expression and cell proliferation associated with NADH oxidase in rat mesangial cellsQ28565638
RNA silencing in vivo reveals role of p22phox in rat angiotensin slow pressor responseQ28566049
Characterization of renin-angiotensin system enzyme activities in cultured mouse podocytesQ33281856
A novel and specific NADPH oxidase-1 (Nox1) small-molecule inhibitor blocks the formation of functional invadopodia in human colon cancer cellsQ33660799
Comparative effect of direct renin inhibition and AT1R blockade on glomerular filtration barrier injury in the transgenic Ren2 ratQ33727755
Protection of podocytes from hyperhomocysteinemia-induced injury by deletion of the gp91phox geneQ33729668
Redox signaling via lipid raft clustering in homocysteine-induced injury of podocytesQ33733309
Reactive oxygen species as mediators of angiotensin II signalingQ34019811
NADPH oxidases regulate CD44 and hyaluronic acid expression in thrombin-treated vascular smooth muscle cells and in atherosclerosis.Q34074465
NMDA receptor-mediated activation of NADPH oxidase and glomerulosclerosis in hyperhomocysteinemic ratsQ34222583
Comparative pharmacology of chemically distinct NADPH oxidase inhibitorsQ34269250
AMP-activated protein kinase (AMPK) negatively regulates Nox4-dependent activation of p53 and epithelial cell apoptosis in diabetes.Q34333672
Effect of chenodeoxycholic acid on fibrosis, inflammation and oxidative stress in kidney in high-fructose-fed Wistar ratsQ34403105
Inhibition of integrin-linked kinase blocks podocyte epithelial-mesenchymal transition and ameliorates proteinuriaQ34729973
Inhibition of mineralocorticoid receptor is a renoprotective effect of the 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor pitavastatin.Q34759691
Immunosuppressive and anti-inflammatory mechanisms of triptolide, the principal active diterpenoid from the Chinese medicinal herb Tripterygium wilfordii Hook. f.Q35060172
Acid sphingomyelinase gene deficiency ameliorates the hyperhomocysteinemia-induced glomerular injury in miceQ35474438
Reversal by growth hormone of homocysteine-induced epithelial-to-mesenchymal transition through membrane raft-redox signaling in podocytesQ35564803
Roles of oxidative stress and antioxidant therapy in chronic kidney disease and hypertensionQ35748416
Insulin increases surface expression of TRPC6 channels in podocytes: role of NADPH oxidases and reactive oxygen speciesQ35780729
Epithelial-to-mesenchymal transition in podocytes mediated by activation of NADPH oxidase in hyperhomocysteinemiaQ35821693
Protective effects of leukemia inhibitory factor against oxidative stress during high glucose-induced apoptosis in podocytesQ36010534
The NOX toolbox: validating the role of NADPH oxidases in physiology and diseaseQ36060782
Nox2 is a mediator of chronic CsA nephrotoxicityQ36131113
Nox4 involvement in TGF-beta and SMAD3-driven induction of the epithelial-to-mesenchymal transition and migration of breast epithelial cells.Q36252551
Sustained activation of N-methyl-D-aspartate receptors in podoctyes leads to oxidative stress, mobilization of transient receptor potential canonical 6 channels, nuclear factor of activated T cells activation, and apoptotic cell deathQ36294421
Matrix compliance regulates Rac1b localization, NADPH oxidase assembly, and epithelial-mesenchymal transitionQ36312242
Hereditary proteinuria syndromes and mechanisms of proteinuriaQ36435101
The podocyte's response to injury: role in proteinuria and glomerulosclerosisQ36474870
Oxidants in chronic kidney diseaseQ36682519
NADPH oxidase-mediated triggering of inflammasome activation in mouse podocytes and glomeruli during hyperhomocysteinemiaQ36731427
Membranous nephropathyQ36844203
Aldosterone and glomerular podocyte injuryQ37101361
Activation of Nod-like receptor protein 3 inflammasomes turns on podocyte injury and glomerular sclerosis in hyperhomocysteinemiaQ37121306
Genetic deficiency of NADPH oxidase does not diminish, but rather enhances, LPS-induced acute inflammatory responses in vivoQ37136614
Contribution of guanine nucleotide exchange factor Vav2 to hyperhomocysteinemic glomerulosclerosis in ratsQ37151470
Mechanisms of podocyte injury in diabetes: role of cytochrome P450 and NADPH oxidasesQ37163466
Mineralocorticoid receptor antagonism attenuates glomerular filtration barrier remodeling in the transgenic Ren2 rat.Q37190283
Attenuation of NADPH oxidase activation and glomerular filtration barrier remodeling with statin treatmentQ37196829
Fulvene-5 potently inhibits NADPH oxidase 4 and blocks the growth of endothelial tumors in mice.Q37286610
NADPH oxidase is the primary source of superoxide induced by NMDA receptor activationQ37353163
NADPH oxidase-derived reactive oxygen species: involvement in vascular physiology and pathologyQ37807273
NADPH oxidase 1 overexpression enhances invasion via matrix metalloproteinase-2 and epithelial-mesenchymal transition in melanoma cellsQ39362677
The roles of connective tissue growth factor and integrin-linked kinase in high glucose-induced phenotypic alterations of podocytesQ39474702
First in Class, Potent, and Orally Bioavailable NADPH Oxidase Isoform 4 (Nox4) Inhibitors for the Treatment of Idiopathic Pulmonary FibrosisQ39645010
Triptolide reduces proteinuria in experimental membranous nephropathy and protects against C5b-9-induced podocyte injury in vitro.Q39717376
Metformin induces suppression of NAD(P)H oxidase activity in podocytes.Q39745297
Expression of functional CCR and CXCR chemokine receptors in podocytesQ40726391
Nebivolol reduces proteinuria and renal NADPH oxidase-generated reactive oxygen species in the transgenic Ren2 rat.Q41896349
The origins and drivers of insulin resistanceQ42274713
NADPH oxidase-derived ROS contributes to upregulation of TRPC6 expression in puromycin aminonucleoside-induced podocyte injuryQ43243103
Accumulation of advanced oxidation protein products induces podocyte apoptosis and deletion through NADPH-dependent mechanismsQ43281714
Losartan metabolite EXP3179 blocks NADPH oxidase-mediated superoxide production by inhibiting protein kinase C: potential clinical implications in hypertensionQ43290562
Reactive oxygen species alter gene expression in podocytes: induction of granulocyte macrophage-colony-stimulating factorQ43829973
Increased expression of NAD(P)H oxidase subunits, NOX4 and p22phox, in the kidney of streptozotocin-induced diabetic rats and its reversibity by interventive insulin treatmentQ44589042
Role of Oxidative Stress in Endothelial Dysfunction and Enhanced Responses to Angiotensin II of Afferent Arterioles from Rabbits Infused with Angiotensin IIQ44625397
Abrogation of oxidative stress improves insulin sensitivity in the Ren-2 rat model of tissue angiotensin II overexpressionQ45115249
Triptolide protects podocytes from puromycin aminonucleoside induced injury in vivo and in vitroQ46570250
Glucose-induced reactive oxygen species cause apoptosis of podocytes and podocyte depletion at the onset of diabetic nephropathyQ46870214
Insulin resistance, oxidative stress, and podocyte injury: role of rosuvastatin modulation of filtration barrier injury.Q46968473
P275copyright licenseCreative Commons Attribution 3.0 UnportedQ14947546
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P921main subjectpodocyteQ138912
reactive oxygen speciesQ424361
proteinuriaQ570197
renin–angiotensin systemQ898218
NADPH oxidasesQ97651124
P304page(s)839761
P577publication date2013-11-11
P1433published inBioMed Research InternationalQ17509958
P1476titleRole of NADPH oxidase-mediated reactive oxygen species in podocyte injury
P478volume2013

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cites work (P2860)
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