Growth hormone prevents the development of autoimmune diabetes

scientific article

Growth hormone prevents the development of autoimmune diabetes is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2013PNAS..110E4619V
P356DOI10.1073/PNAS.1314985110
P8608Fatcat IDrelease_e3ksuiczr5f3vg6jdwm7guyt4m
P932PMC publication ID3845149
P698PubMed publication ID24218587
P5875ResearchGate publication ID258446207

P50authorRicardo VillaresQ64437871
Dimitri KakabadseQ86706204
Mario MelladoQ40325581
P2093author name stringCarlos Martínez-A
Rosa P Gomariz
Yasmina Juarranz
P2860cites workT helper 17 cell heterogeneity and pathogenicity in autoimmune diseaseQ24609737
The neurosurvival factor Humanin inhibits beta-cell apoptosis via signal transducer and activator of transcription 3 activation and delays and ameliorates diabetes in nonobese diabetic miceQ24619125
T helper 17 cells promote cytotoxic T cell activation in tumor immunityQ24646584
Growth hormone mitigates against lethal irradiation and enhances hematologic and immune recovery in mice and nonhuman primatesQ27325260
Bovine growth hormone transgenic mice are resistant to diet-induced obesity but develop hyperphagia, dyslipidemia, and diabetes on a high-fat diet.Q45147939
Pancreatic remodeling: beta-cell apoptosis, proliferation and neogenesis, and the measurement of beta-cell mass and of individual beta-cell size.Q45979032
Recombinant human growth hormone modulates Th1 and Th2 cytokine response in burned miceQ47816193
Growth hormone receptors and immunocompetent cellsQ47966541
Insulin-like growth factors prevent cytokine-mediated cell death in isolated islets of Langerhans from pre-diabetic non-obese diabetic mice.Q50519404
Targeted expression of placental lactogen in the beta cells of transgenic mice results in beta cell proliferation, islet mass augmentation, and hypoglycemia.Q51556341
Suppression of SOCS3 expression in the pancreatic beta-cell leads to resistance to type 1 diabetes.Q53547433
B lymphocytes are critical antigen-presenting cells for the initiation of T cell-mediated autoimmune diabetes in nonobese diabetic mice.Q54120741
A comprehensive genetic map of the mouse genome.Q54223711
Beta cell proliferation and growth factors.Q54334153
Deficiency in NOD antigen-presenting cell function may be responsible for suboptimal CD4+CD25+ T-cell-mediated regulation and type 1 diabetes development in NOD mice.Q54594961
Regulatory T-cell functions are subverted and converted owing to attenuated Foxp3 expressionQ59048389
Expanded T cells from pancreatic lymph nodes of type 1 diabetic subjects recognize an insulin epitopeQ59060541
Immunologic disparity in the hypopituitary dwarf mouseQ68053179
Immunologic and hematologic effects of neuroendocrine hormones. Studies on DW/J dwarf miceQ68148407
Recombinant human growth hormone stimulates B cell immunoglobulin synthesis and proliferation in serum-free mediumQ68231110
Enterotoxin septic shock protection and deficient T helper 2 cytokine production in growth hormone transgenic miceQ71687730
Effects of bovine growth hormone (bGH) transgene expression or bGH treatment on reproductive functions in female miceQ71936380
Direct effects of rat growth hormone in rat islets of langerhans in tissues cultureQ72152553
Glucose metabolism in transgenic mice containing a chimeric P-enolpyruvate carboxykinase/bovine growth hormone geneQ72829677
Growth hormone stimulates the proliferation of activated mouse T lymphocytesQ73251501
Abnormalities in dendritic cell and macrophage accumulation in the pancreas of nonobese diabetic (NOD) mice during the early neonatal periodQ77969660
Dynamics of pathogenic and suppressor T cells in autoimmune diabetes developmentQ79125427
STAT5 activity in pancreatic beta-cells influences the severity of diabetes in animal models of type 1 and 2 diabetesQ79143532
Cyclophosphamide-induced type-1 diabetes in the NOD mouse is associated with a reduction of CD4+CD25+Foxp3+ regulatory T cellsQ79326703
Upregulation of Foxp3 expression in mouse and human Treg is IL-2/STAT5 dependent: implications for the NOD STAT5B mutation in diabetes pathogenesisQ79386860
IL-17 plays an important role in the development of experimental autoimmune encephalomyelitisQ79755041
The role of STAT3 in antigen-IgG inducing regulatory CD4(+)Foxp3(+)T cellsQ80794020
Alternative activation of macrophagesQ27860939
Regulation of signal transducer and activator of transcription (STAT) 5b activation by the temporal pattern of growth hormone stimulationQ28564645
Macrophage activation and polarizationQ29616353
APC activation restores functional CD4(+)CD25(+) regulatory T cells in NOD mice that can prevent diabetes developmentQ33384634
The incidence of type-1 diabetes in NOD mice is modulated by restricted flora not germ-free conditionsQ33833767
IGF-I and GH post-receptor signaling mechanisms for pancreatic beta-cell replicationQ33928187
Primer-BLAST: a tool to design target-specific primers for polymerase chain reactionQ34307627
Prime role for an insulin epitope in the development of type 1 diabetes in NOD miceQ34345367
TGF-beta and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain T(H)-17 cell-mediated pathologyQ34712326
Immunoregulatory pathways controlling progression of autoimmunity in NOD miceQ34920085
A multivalent vaccine for type 1 diabetes skews T cell subsets to Th2 phenotype in NOD mice.Q35004055
Growth hormone receptor regulates β cell hyperplasia and glucose-stimulated insulin secretion in obese miceQ35015695
Tumour necrosis factor alpha blockade induces an anti-inflammatory growth hormone signalling pathway in experimental colitis.Q35761249
Gender differences in autoimmunity associated with exposure to environmental factorsQ35827986
Full restoration of peripheral Foxp3+ regulatory T cell pool by radioresistant host cells in scurfy bone marrow chimerasQ35829151
Cutting edge: IL-10-mediated tristetraprolin induction is part of a feedback loop that controls macrophage STAT3 activation and cytokine productionQ36179832
Preferential recruitment of CCR6-expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its animal model.Q36229199
The interactions of dendritic cells with antigen-specific, regulatory T cells that suppress autoimmunityQ36392364
Intrinsic regulators of pancreatic beta-cell proliferationQ36528824
Environmental factors in the development of Type 1 diabetesQ36699160
IL-17 stimulates differentiation of human anti-inflammatory macrophages and phagocytosis of apoptotic neutrophils in response to IL-10 and glucocorticoids.Q36916386
The defect in T-cell regulation in NOD mice is an effect on the T-cell effectorsQ37018786
Highly purified Th17 cells from BDC2.5NOD mice convert into Th1-like cells in NOD/SCID recipient miceQ37111353
Mouse models for the study of autoimmune type 1 diabetes: a NOD to similarities and differences to human diseaseQ37737987
Developmental regulation and tissue-specific expression of a chimaeric phosphoenolpyruvate carboxykinase/bovine growth hormone gene in transgenic animalsQ37964120
TH17 Cells in Autoimmunity and Immunodeficiency: Protective or Pathogenic?Q38016854
Influence of glucocorticoids and growth hormone on insulin sensitivity in humansQ38091130
Autoimmune islet destruction in spontaneous type 1 diabetes is not beta-cell exclusive.Q38358439
Inhibition of autoimmune diabetes by TLR2 toleranceQ39458253
Role of STAT3 in CD4+CD25+FOXP3+ regulatory lymphocyte generation: implications in graft-versus-host disease and antitumor immunityQ40048350
Tumor necrosis factor alpha blockade restores growth hormone signaling in murine colitisQ40424076
Growth hormone modulates thymocyte development in vivo through a combined action of laminin and CXC chemokine ligand 12.Q40433848
Enhancement of human granulopoiesis in vitro by biosynthetic insulin-like growth factor I/somatomedin C and human growth hormoneQ41016804
The somatogenic hormones and insulin-like growth factor-1: stimulators of lymphopoiesis and immune functionQ41430668
Target cell expression of suppressor of cytokine signaling-1 prevents diabetes in the NOD mouse.Q44631808
Human anti-inflammatory macrophages induce Foxp3+ GITR+ CD25+ regulatory T cells, which suppress via membrane-bound TGFbeta-1.Q44823001
P433issue48
P407language of work or nameEnglishQ1860
P304page(s)E4619-27
P577publication date2013-11-11
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleGrowth hormone prevents the development of autoimmune diabetes
P478volume110

Reverse relations

cites work (P2860)
Q36268429Beneficial effects of growth hormone-releasing hormone agonists on rat INS-1 cells and on streptozotocin-induced NOD/SCID mice
Q61812304Dexamethasone during pregnancy impairs maternal pancreatic β-cell renewal during lactation
Q37001887Growth hormone treatment of premature ovarian failure in a mouse model via stimulation of the Notch-1 signaling pathway
Q92096745Growth hormone-mediated reprogramming of macrophage transcriptome and effector functions
Q54951184Inhibitory Role of Growth Hormone in the Induction and Progression Phases of Collagen-Induced Arthritis.
Q55337327Interactions Between the Neuroendocrine System and T Lymphocytes in Diabetes.
Q35871156Recombinant human growth hormone in treatment of diabetes: report of three cases and review of relative literature
Q36119029The Relationship between Metabolic Control and Growth in Children with Type I Diabetes Mellitus in Southwest of Iran
Q41662753The beneficial effect of growth hormone treatment on islet mass in streptozotocin-treated mice
Q30413135The role of macrophage polarization in infectious and inflammatory diseases

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