New evidence-based adaptive clinical trial methods for optimally integrating predictive biomarkers into oncology clinical development programs

scientific article published on 15 March 2013

New evidence-based adaptive clinical trial methods for optimally integrating predictive biomarkers into oncology clinical development programs is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.5732/CJC.012.10248
P8608Fatcat IDrelease_k2oppnaex5bjzo63ljrjb7t37m
P932PMC publication ID3845554
P698PubMed publication ID23489587
P5875ResearchGate publication ID236045596

P2093author name stringCong Chen
Robert A Beckman
P2860cites workIntegrating predictive biomarkers and classifiers into oncology clinical development programmesQ37940788
Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic diseaseQ40630247
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Biomarkers in phase I oncology trials: signal, noise, or expensive distraction?Q79843510
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Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancerQ28271324
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Randomized clinical trials with biomarkers: design issuesQ34024227
Pharmacogenetics and pharmacogenomics in oncology therapeutic antibody development.Q34461037
Cancer biomarkers--an invitation to the tableQ34530963
Use of archived specimens in evaluation of prognostic and predictive biomarkersQ35007222
Genetic instability in cancer: theory and experimentQ36206964
Surrogate end points for median overall survival in metastatic colorectal cancer: literature-based analysis from 39 randomized controlled trials of first-line chemotherapy.Q36944493
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Efficiency of carcinogenesis: is the mutator phenotype inevitable?Q37799101
P433issue5
P921main subjectbiomarkerQ864574
P304page(s)233-241
P577publication date2013-03-15
P1433published inChinese Journal of CancerQ15760211
P1476titleNew evidence-based adaptive clinical trial methods for optimally integrating predictive biomarkers into oncology clinical development programs
P478volume32

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cites work (P2860)
Q90754603A systems approach to clinical oncology uses deep phenotyping to deliver personalized care
Q42732448Molecular targeted agents--where we are and where we are going
Q41356511Targeted therapy: resistance and re-sensitization

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