Aldosterone and dexamethasone stimulate calcineurin activity through a transcription-independent mechanism involving steroid receptor-associated heat shock proteins

scientific article published on March 1997

Aldosterone and dexamethasone stimulate calcineurin activity through a transcription-independent mechanism involving steroid receptor-associated heat shock proteins is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1172/JCI119278
P932PMC publication ID507935
P698PubMed publication ID9077529
P5875ResearchGate publication ID14135804

P2093author name stringC L Smith
C E Swanson
J A Tumlin
J P Lea
J S Someren
S S Edge
P2860cites workAssociation of a 59-kilodalton immunophilin with the glucocorticoid receptor complexQ24292784
Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applicationsQ24561689
Structure and expression of two isoforms of the murine calmodulin-dependent protein phosphatase regulatory subunit (calcineurin B)Q28513944
Aldosterone-induced increase in protein phosphatase activity of toad bladderQ35127978
Regulation by aldosterone of Na+,K+-ATPase mRNAs, protein synthesis, and sodium transport in cultured kidney cellsQ36216120
The immunosuppressive and toxic effects of FK-506 are mechanistically related: pharmacology of a novel antagonist of FK-506 and rapamycinQ36231731
Regulation of the Na-K pump of the rat cortical collecting tubule by aldosteroneQ36435167
FK506 and rapamycin: novel pharmacological probes of the immune responseQ36654786
Binding of heat shock proteins to the avian progesterone receptorQ36760351
Calcineurin mediates alpha-adrenergic stimulation of Na+,K(+)-ATPase activity in renal tubule cellsQ37148260
Transformation of glucocorticoid and progesterone receptors to the DNA-binding stateQ39674276
The role of heat shock proteins in regulating the function, folding, and trafficking of the glucocorticoid receptorQ40863456
Evidence for a functional interaction between calmodulin and the glucocorticoid receptorQ41361080
Potentiation of glucocorticoid receptor-mediated gene expression by the immunophilin ligands FK506 and rapamycinQ41565352
Evidence that the inhibition of Na+/K(+)-ATPase activity by FK506 involves calcineurinQ41663844
Inhibitory effect of okadaic acid on the p-nitrophenyl phosphate phosphatase activity of protein phosphatasesQ42161949
Rapid effects of aldosterone on sodium transport in vascular smooth muscle cellsQ42488772
P59, an hsp 90-binding protein. Cloning and sequencing of its cDNA and preparation of a peptide-directed polyclonal antibodyQ42608880
Expression of Na-K-ATPase alpha- and beta-subunit mRNA and protein isoforms in the rat nephronQ48182766
Stimulation of apical Na permeability and basolateral Na pump of toad urinary bladder by aldosterone.Q52648088
Nongenomic effects of aldosterone on intracellular Ca2+ in vascular smooth muscle cells.Q53856893
Expression of calcineurin activity and alpha-subunit isoforms in specific segments of the rat nephron.Q54162046
Early effects of aldosterone on Na-K pump in rat cortical collecting tubulesQ68469555
Aldose reductase activities in microdissected rat renal tubule segmentsQ69189402
Cytoplasmic 8 S glucocorticoid receptor binds to actin filaments through the 90-kDa heat shock protein moietyQ70146882
Effects of immunosuppressants FK506 and rapamycin on the heterooligomeric form of the progesterone receptorQ71614951
Nephron segment-specific inhibition of Na+/K(+)-ATPase activity by cyclosporin AQ72949491
Purified mammalian HSP-70 KDA activates phosphoprotein phosphatases in vitroQ72968484
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectdexamethasoneQ422252
P304page(s)1217-1223
P577publication date1997-03-01
P1433published inJournal of Clinical InvestigationQ3186904
P1476titleAldosterone and dexamethasone stimulate calcineurin activity through a transcription-independent mechanism involving steroid receptor-associated heat shock proteins
P478volume99

Reverse relations

cites work (P2860)
Q40536291Aldosterone rapidly activates Src kinase in M-1 cells involving the mineralocorticoid receptor and HSP84.
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Q30549880Calcineurin is required in urinary tract mesenchyme for the development of the pyeloureteral peristaltic machinery.
Q35188070Comparison of direct action of thiazolidinediones and glucocorticoids on renal podocytes: protection from injury and molecular effects
Q34279367Cross-talk between glucocorticoid receptor and AP-1.
Q33731974Early aldosterone action: toward filling the gap between transcription and transport
Q41661413Expression and function of calcineurin in the mammalian nephron: physiological roles, receptor signaling, and ion transport
Q34283324Gender differences in autoimmunity: molecular basis for estrogen effects in systemic lupus erythematosus
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Q41755679NFATc1 activity regulates the expression of myocilin induced by dexamethasone
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Q54444599Rapid nongenomic action of aldosterone on protein expressions of Hsp90( α and β ) and pc-Src in rat kidney.
Q57275237Renal ischemia-reperfusion injury is prevented by the mineralocorticoid receptor blocker spironolactone
Q28645766Sodium-potassium-adenosinetriphosphatase-dependent sodium transport in the kidney: hormonal control
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