Molecular alterations associated with aneurysmal remodeling are localized in the high hemodynamic stress region of a created carotid bifurcation

scientific article published on July 2009

Molecular alterations associated with aneurysmal remodeling are localized in the high hemodynamic stress region of a created carotid bifurcation is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1227/01.NEU.0000343541.85713.01
P932PMC publication ID2754173
P698PubMed publication ID19574839

P50authorJohn KolegaQ37372228
Daniel D SwartzQ57729188
Elad LevyQ64740425
J. MoccoQ87846362
P2093author name stringLing Gao
Hui Meng
Zhijie Wang
Yiemeng Hoi
P2860cites workNitric oxide and peroxynitrite in health and diseaseQ24645400
Endothelial nitric oxide synthase in vascular disease: from marvel to menaceQ28305279
Molecular mechanisms of iNOS induction by IL-1 beta and IFN-gamma in rat aortic smooth muscle cellsQ28574444
Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and uglyQ29547442
Structural fragility and inflammatory response of ruptured cerebral aneurysms. A comparative study between ruptured and unruptured cerebral aneurysmsQ30726132
Expression of inducible nitric oxide synthase after endothelial denudation of the rat carotid artery: role of plateletsQ33504491
Nitric oxide and infectious diseasesQ33734476
Nitric oxide and the proliferation of vascular smooth muscle cellsQ33847601
Genesis of cerebral aneurysms--an updateQ34324725
Toward functional genomics of flow-induced outward remodeling of resistance arteriesQ36038066
Nitric oxide and cell proliferation.Q36480540
Mechanotransduction and endothelial cell homeostasis: the wisdom of the cellQ36650981
Nitric oxide-dependent stimulation of endothelial cell proliferation by sustained high flow.Q36844691
Cerebral aneurysms arising at nonbranching sites. An experimental StudyQ36847411
Nascent aneurysm formation at the basilar terminus induced by hemodynamics.Q36919762
Complex hemodynamics at the apex of an arterial bifurcation induces vascular remodeling resembling cerebral aneurysm initiation.Q37272479
Reactive oxygen species produced by macrophage-derived foam cells regulate the activity of vascular matrix metalloproteinases in vitro. Implications for atherosclerotic plaque stabilityQ37361893
A model system for mapping vascular responses to complex hemodynamics at arterial bifurcations in vivoQ37367891
Endothelial nitric oxide synthase activity is linked to its presence at cell-cell contactsQ40759918
Apoptosis of medial smooth muscle cells in the development of saccular cerebral aneurysms in ratsQ40871800
The vascular biology of nitric oxide and its role in atherogenesisQ40960152
Early changes of experimentally induced cerebral aneurysms in rats. Light-microscopic studyQ42050979
p47phox-dependent NADPH oxidase regulates flow-induced vascular remodelingQ46658437
Identification of a serum gelatinase associated with the occurrence of cerebral aneurysms as pro-matrix metalloproteinase-2.Q47675736
High flow drives vascular endothelial cell proliferation during flow-induced arterial remodeling associated with the expression of vascular endothelial growth factorQ47792919
Analysis of the effect of disturbed flow on monocytic adhesion to endothelial cellsQ51798668
Matrix metalloproteinase-9 in cerebral aneurysms.Q52527315
Impaired progression of cerebral aneurysms in interleukin-1beta-deficient mice.Q52568473
Hemodynamics and the focal origin of atherosclerosis: a spatial approach to endothelial structure, gene expression, and function.Q53981889
Macrophage-derived matrix metalloproteinase-2 and -9 promote the progression of cerebral aneurysms in rats.Q54570193
Vascular endothelium responds to fluid shear stress gradientsQ67570891
Pathophysiology of development and rupture of cerebral aneurysmsQ68894280
Intracranial aneurysmsQ71908767
Shear stress induces iNOS expression in cultured smooth muscle cells: role of oxidative stressQ73190943
Prevention of rat cerebral aneurysm formation by inhibition of nitric oxide synthaseQ73834420
Shear level influences resistance artery remodeling: wall dimensions, cell density, and eNOS expressionQ74403736
Effects of disturbed flow on endothelial cellsQ74802764
Vascular extracellular matrix remodeling in cerebral aneurysmsQ77180718
Histopathology of cerebral aneurysmsQ79644640
Impact of IL-1beta on flow-induced outward arterial remodelingQ80427653
Endothelial injury and inflammatory response induced by hemodynamic changes preceding intracranial aneurysm formation: experimental study in ratsQ80788995
Pathogenesis, natural history, and treatment of unruptured intracranial aneurysmsQ81131259
P4510describes a project that usesImageJQ1659584
P433issue1
P407language of work or nameEnglishQ1860
P921main subjecthemodynamicsQ1642137
P304page(s)169-77; discussion 177-8
P577publication date2009-07-01
P1433published inNeurosurgeryQ7002693
P1476titleMolecular alterations associated with aneurysmal remodeling are localized in the high hemodynamic stress region of a created carotid bifurcation
P478volume65

Reverse relations

cites work (P2860)
Q38052432"Sit back, observe, and wait." Or is there a pharmacologic preventive treatment for cerebral aneurysms?
Q34974232A comparative review of the hemodynamics and pathogenesis of cerebral and abdominal aortic aneurysms: lessons to learn from each other
Q92023931Aneurysm Formation, Growth, and Rupture: The Biology and Physics of Cerebral Aneurysms
Q40213926Arterial wall degeneration plus hemodynamic insult cause arterial wall remodeling and nascent aneurysm formation at specific sites in dogs
Q38709966Basic Principles of Hemodynamics and Cerebral Aneurysms
Q36211346Biology of intracranial aneurysms: role of inflammation
Q33356519CFD: computational fluid dynamics or confounding factor dissemination? The role of hemodynamics in intracranial aneurysm rupture risk assessment
Q34035707Characterization of critical hemodynamics contributing to aneurysmal remodeling at the basilar terminus in a rabbit model
Q88147610Computational Fluid Dynamics of Vascular Disease in Animal Models
Q34175309Curvature effect on hemodynamic conditions at the inner bend of the carotid siphon and its relation to aneurysm formation.
Q39372802Daughter Sac Formation Related to Blood Inflow Jet in an Intracranial Aneurysm
Q44932973De novo cerebral aneurysm formation associated with proximal stenosis.
Q37234596Differential gene expression by endothelial cells under positive and negative streamwise gradients of high wall shear stress
Q35900684Endothelial cells express a unique transcriptional profile under very high wall shear stress known to induce expansive arterial remodeling
Q38168729Factors affecting formation and rupture of intracranial saccular aneurysms
Q88515524Hemodynamic Stress, Inflammation, and Intracranial Aneurysm Development and Rupture: A Systematic Review
Q57728730Hemodynamic vascular biomarkers for initiation of paraclinoid internal carotid artery aneurysms using patient-specific computational fluid dynamic simulation based on magnetic resonance imaging
Q39784094Hemodynamics of cerebral aneurysm initiation: the role of wall shear stress and spatial wall shear stress gradient.
Q39546243High fluid shear stress and spatial shear stress gradients affect endothelial proliferation, survival, and alignment
Q36800232High wall shear stress and spatial gradients in vascular pathology: a review
Q48106770Identification of vortex structures in a cohort of 204 intracranial aneurysms.
Q58715416Increased MMP activity in curved geometries disrupts the endothelial cell glycocalyx creating a proinflammatory environment
Q38693096Intercorrelations of morphology with hemodynamics in intracranial aneurysms in computational fluid dynamics
Q43979148Intracranial stents being modeled as a porous medium: flow simulation in stented cerebral aneurysms
Q83862487Intracranial stents for aneurysms: mere scaffold or hemodynamic therapy?
Q50929808Morphological and Hemodynamic Differences Between Aneurysmal Middle Cerebral Artery Bifurcation and Contralateral Nonaneurysmal Anatomy.
Q55024984NF-κB-Mediated Inflammation in the Pathogenesis of Intracranial Aneurysm and Subarachnoid Hemorrhage. Does Autophagy Play a Role?
Q88563464One-stage Stent-assisted Coil Embolization for Rupture-side-unknown Bilateral Vertebral Artery Dissecting Aneurysms in an Acute Stage: A Case Report
Q92069295Potential Therapeutic Strategies for Intracranial Aneurysms Targeting Aneurysm Pathogenesis
Q87625004Proximal stenosis may induce initiation of cerebral aneurysms by increasing wall shear stress and wall shear stress gradient
Q61446471Real-time Imaging of an Experimental Intracranial Aneurysm in Rats
Q43808301Report of two cases of a rare cause of subarachnoid hemorrhage including unusual presentation and an emerging and effective treatment option
Q26830831Review of cerebral aneurysm formation, growth, and rupture
Q37802519Role of hemodynamic shear stress in cardiovascular disease
Q35771077Statistical wall shear stress maps of ruptured and unruptured middle cerebral artery aneurysms
Q53143741Stent-assisted coil embolization and computational fluid dynamics simulations of bilateral vertebral artery dissecting aneurysms presenting with subarachnoid hemorrhage: case report.
Q34479255The development and the use of experimental animal models to study the underlying mechanisms of CA formation.
Q42560358The effects of aortic coarctation on cerebral hemodynamics and its importance in the etiopathogenesis of intracranial aneurysms
Q37423992The expression of SIRT1 in articular cartilage of patients with knee osteoarthritis and its correlation with disease severity
Q47397565Timing and size of flow impingement in a giant intracranial aneurysm at the internal carotid artery

Search more.